PRECISion medicinE Across the Disease Continuum to Prevent and Treat Rheumatoid Arthritis
NCT04482335 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 500
Last updated 2021-10-06
Summary
The study will recruit patients referred to the Rheumatology Out-patient departments. Patients will be recruited to the study or control groups (healthy or disease controls who will be age and sex-matched) as needed. The study will first open to recruitment at Manchester University Hospitals NHS Foundation Trust and then open at other NHS Trusts. Patients will be asked to participate in longitudinal (clinical/imaging/biosample) data and/or sample collection that will improve our understanding of underlying disease mechanisms and identify improved diagnostic, prognostic and predictive biomarkers to understand progression of disease and drug response or resistance.
Conditions
Interventions
- OTHER
-
No intervention
No intervention
Sponsors & Collaborators
-
University of Manchester
lead OTHER
Eligibility
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2021-05-15
- Primary Completion
- 2025-10-01
- Completion
- 2025-10-01
Countries
- United Kingdom
Study Locations
More Related Trials
-
Post-marketing Observational Study in Subjects With Rheumatoid Arthritis
NCT00234884 ·Status: COMPLETED
-
A Study to Evaluate the Efficacy and Safety of MLTA3698A in Combination With a Disease-Modifying Anti-Rheumatic Drug (DMARD) Compared With Adalimumab in Combination With a DMARD in Patients With Active Rheumatoid Arthritis
NCT01225393 ·Status: COMPLETED ·Phase: PHASE2
-
Study of the Articular Microbiota in Rheumatoid Arthritis.
NCT04056234 ·Status: COMPLETED
-
Clinical Disease Activity and Modulation of Synovial Lymphoid Structures and B Cell Function in Rheumatoid Arthritis
NCT02528292 ·Status: UNKNOWN
-
Optimal Management of Rheumatoid Arthritis Patients Requiring Biologic Therapy
NCT01021735 ·Status: COMPLETED ·Phase: PHASE4
-
Medical Trial: Appraising Medical Trial Experiences of Rheumatoid Arthritis Patients
NCT05398471 ·Status: NOT_YET_RECRUITING
-
Therapeutic Strategy in Patients Treated With Methotrexate for Rheumatoid Arthritis
NCT02288520 ·Status: COMPLETED
-
To Evaluate The Efficacy And Safety Of Sunpharma1505 Compared With Reference1505 In Subjects With Active Rheumatoid Arthritis
NCT02534896 ·Status: TERMINATED ·Phase: PHASE3
-
An Observational Study on Long-Term Efficacy and Safety of RoActemra/Actemra (Tocilizumab) in Patients With Moderate to Severe Rheumatoid Arthritis (FAct)
NCT01483326 ·Status: COMPLETED
-
Study of Arthritis and Related Conditions
NCT00006333 ·Status: COMPLETED
-
Treatment of TNFa Naive Patients With Poor Prognosis Rheumatoid Arthritis
NCT00963703 ·Status: COMPLETED ·Phase: NA
-
Methotrexate Use Improvement in Rheumatoid Arthritis Using Biomarker Feedback
NCT03913728 ·Status: COMPLETED ·Phase: NA
-
A Study to Evaluate BioMarkers in Blood Samples in Subjects With Rheumatoid Arthritis
NCT01209585 ·Status: COMPLETED
-
A Study in Rheumatoid Arthritis
NCT01253265 ·Status: COMPLETED ·Phase: PHASE1
-
Observational Safety Study of Rituximab in Patients Diagnosed With Rheumatoid Arthritis (RA) Who Did Not Respond Adequately to TNF-alpha Blocker
NCT02322801 ·Status: COMPLETED
-
Remission and Joint Damage Progression in Early Rheumatoid Arthritis
NCT00122382 ·Status: COMPLETED ·Phase: PHASE3
-
An Observational, Prospective Study to Assess the Efficacy and Safety of Adalloce in Patients With RA and AS
NCT05835518 ·Status: RECRUITING
-
A Phase 2 Dose-finding Study of Atacicept in Subjects With Rheumatoid Arthritis (AUGUST I)
NCT00430495 ·Status: COMPLETED ·Phase: PHASE2
-
A Long Term Roll-over Study to Investigate the Efficacy and Safety of Adalimumab Given Long-term to Patients With Rheumatoid Arthritis
NCT00233571 ·Status: COMPLETED ·Phase: PHASE3
-
Quality of Life Study With Adalimumab in Rheumatoid Arthritis
NCT00234936 ·Status: COMPLETED ·Phase: PHASE3
-
An Global Comparative Observational Study of RoActemra/Actemra (Tocilizumab) in Patients With Rheumatoid Arthritis
NCT01543503 ·Status: COMPLETED
-
Open Label Study to Assess the Predictability of Early Response to Certolizumab Pegol in Patients With Rheumatoid Arthritis
NCT01443364 ·Status: COMPLETED ·Phase: PHASE4
-
Safety and Efficacy of ACZ885 in Adult Patients With Established Rheumatoid Arthritis
NCT00504595 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluation of the Condition of Rheumatoid Arthritis After Treatment
NCT02157012 ·Status: UNKNOWN ·Phase: PHASE4
-
Study Evaluating Multiple Doses Of ATN-103 In Subjects With Active Rheumatoid Arthritis
NCT00959036 ·Status: COMPLETED ·Phase: PHASE1/PHASE2