Treatment of TNFa Naive Patients With Poor Prognosis Rheumatoid Arthritis
NCT00963703 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 15
Last updated 2012-03-20
Summary
The purpose of this study is to determine how well Rituximab works in early stages of disease and the effects it has on an inflamed joint and blood cells.
This will allow the investigators to get a better understanding of how this treatment affects the inflamed joints of rheumatoid arthritis (RA) patients.
Conditions
Interventions
- DRUG
-
Rituximab 1000 mg Intravenously day 1 and day 15
Sponsors & Collaborators
- collaborator INDUSTRY
-
University of Manitoba
lead OTHER
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2007-12-31
- Primary Completion
- 2012-03-31
- Completion
- 2012-03-31
Countries
- Canada
Study Locations
More Related Trials
-
An Observational Study on Patients With Rheumatoid Arthritis Treated With MabThera (Rituximab)
NCT01075477 ·Status: COMPLETED
-
A Study of the Safety of Rituximab in Combination With Other Anti-Rheumatic Drugs in Subjects With Active Rheumatoid Arthritis
NCT00443651 ·Status: COMPLETED ·Phase: PHASE3
-
An Ascending Dose Study of PIT565 in Participants With Rheumatoid Arthritis
NCT07029555 ·Status: RECRUITING ·Phase: PHASE1
-
An Observational Study of MabThera/Rituxan (Rituximab) and Alternative TNF-Inhibitors in Patients With Rheumatoid Arthritis and an Inadequate Response to a Single Previous TNF-Inhibitor
NCT01557348 ·Status: COMPLETED
-
An Observational Quality of Life Study in Participants With Rheumatoid Arthritis Treated With Rituximab
NCT02507752 ·Status: COMPLETED
-
Prospective Validation of a Pharmacological Biomarker for Low-Dose Rituximab in Rheumatoid Arthritis
NCT06933134 ·Status: RECRUITING
-
A Study in Patients With Rheumatoid Arthritis
NCT00966875 ·Status: COMPLETED ·Phase: PHASE2
-
A Pharmacokinetic/Pharmacodynamic Study Comparing PF-05280586 To Rituximab In Subjects With Active Rheumatoid Arthritis With An Inadequate Response To TNF Inhibitors (REFLECTIONS B328-01)
NCT01526057 ·Status: COMPLETED ·Phase: PHASE2
-
Natrunix Versus Methotrexate in Rheumatoid Arthritis
NCT05363917 ·Status: UNKNOWN ·Phase: PHASE2
-
An Observational Study on the Safety and Effectiveness of Rituximab in Patients With Severe Active Rheumatoid Arthritis
NCT01071798 ·Status: COMPLETED
-
A Study of Tocilizumab in Patients With Rheumatoid Arthritis
NCT01187563 ·Status: COMPLETED
-
Study to Assess the Safety and Tolerability of MEDI5117 in Rheumatoid Arthritis Patients
NCT01559103 ·Status: TERMINATED ·Phase: PHASE1
-
A Study of Rituximab (MabThera®/Rituxan®) in Patients With Rheumatoid Arthritis and Inadequate Response to Methotrexate
NCT00578305 ·Status: COMPLETED ·Phase: PHASE3
-
A Retrospective Observational Study on the Use of Biologics in Monotherapy in Patients With Rheumatoid Arthritis
NCT01834807 ·Status: COMPLETED
-
An Efficacy and Safety Study of Infliximab in Participants With Rheumatoid Arthritis
NCT00896168 ·Status: COMPLETED ·Phase: PHASE4
-
A Pilot Study of MabThera (Rituximab) Evaluated by MRI in Patients With Rheumatoid Arthritis.
NCT00502853 ·Status: COMPLETED ·Phase: PHASE4
-
A Study of the Efficacy and Safety of Re-treatments With Rituximab in Patients With Active Rheumatoid Arthritis Who Have Had an Inadequate Response to Anti-tnfa Therapies
NCT02097745 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of PF-06438179 (Infliximab-Pfizer) and Infliximab in Combination With Methotrexate in Subjects With Active Rheumatoid Arthritis (REFLECTIONS B537-02).
NCT02222493 ·Status: COMPLETED ·Phase: PHASE3
-
A Study To Describe The Use Of Tofacitinib After Use Of Rituximab In Patients With Rheumatoid Arthritis In A Real-World Setting
NCT05487703 ·Status: COMPLETED
-
Study of the Articular Microbiota in Rheumatoid Arthritis.
NCT04056234 ·Status: COMPLETED
-
A Study of MabThera (Rituximab) in Patients With Rheumatoid Arthritis Who Have Had an Inadequate Response to a Single Anti-TNF Inhibitor
NCT02079532 ·Status: COMPLETED ·Phase: PHASE3
-
Safety and Efficacy of TAK-715 in Subjects With Rheumatoid Arthritis
NCT00760864 ·Status: COMPLETED ·Phase: PHASE2
-
Extension Study to Assess the Efficacy and Safety of Repeat Treatment With Rituximab (MabThera) in Participants With Active Rheumatoid Arthritis (RA)
NCT02093026 ·Status: COMPLETED ·Phase: PHASE2
-
Rituximab in Rheumatoid Arthritis Lung Disease
NCT00578565 ·Status: COMPLETED ·Phase: PHASE3
-
INCB047986 in Rheumatoid Arthritis
NCT02151474 ·Status: TERMINATED ·Phase: PHASE2