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Genetics of Recurrent Early-Onset Depression

NCT00005914 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 2533

Last updated 2019-04-19

No results posted yet for this study

Summary

This nationwide study will create a DNA collection to permit qualified scientists to search for depression-related genes.

More than 750 families with at least two siblings who have experienced major depression are needed for the study. Participants will be interviewed about psychiatric and family history, and will be asked to provide a small blood specimen. The identification of predisposing genes can lead to greater understanding of the brain mechanisms involved in severe depression which can in turn lead to the discovery of new treatments.

A Certificate of Confidentiality from the federal government ensures that all information will be strictly confidential. Blood specimens are identified only by code number (not by name).

Reimbursement is provided.

Conditions

Sponsors & Collaborators

Principal Investigators

  • Myrna Weissman · Columbia University

  • J R DePaulo · Johns Hopkins University

  • William Scheftner · Rush University Hospital

  • Raymond Crowe · University of Iowa

  • Douglas Levinson · University of Pennsylvania

  • George Zubenko · University of Pittsburgh

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
1999-10-31
Primary Completion
2005-10-31
Completion
2005-10-31

Countries

  • United States

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00005914 on ClinicalTrials.gov