Peripheral Stem Cell Transplantation to Prevent Neutropenia in Patients Receiving Chemotherapy for Relapsed or Refractory Non-Hodgkin's Lymphoma
NCT00005787 · Status: TERMINATED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 3
Last updated 2012-06-01
Summary
RATIONALE: Peripheral stem cell transplantation may be able to replace immune cells that were destroyed by chemotherapy used to kill cancer cells. Treating the peripheral stem cells in the laboratory may improve the effectiveness of the transplant.
PURPOSE: Phase I trial to study the effectiveness of peripheral stem cell transplantation in patients who have relapsed or refractory non-Hodgkin's lymphoma and who will be treated with high-dose chemotherapy.
Conditions
Interventions
- BIOLOGICAL
-
epoetin alfa
- BIOLOGICAL
- BIOLOGICAL
-
recombinant flt3 ligand
- BIOLOGICAL
-
recombinant interleukin-3
- BIOLOGICAL
-
sargramostim
- PROCEDURE
-
in vitro-treated peripheral blood stem cell transplantation
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH - lead OTHER
Principal Investigators
-
Jane N. Winter, MD · Robert H. Lurie Cancer Center
Study Design
- Purpose
- SUPPORTIVE_CARE
Eligibility
- Min Age
- 17 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1999-09-30
- Primary Completion
- 2002-01-31
- Completion
- 2002-01-31
Countries
- United States
Study Locations
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