Prinomastat and Combination Chemotherapy in Treating Patients With Metastatic or Recurrent Non-small Cell Lung Cancer
NCT00004199 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL
Last updated 2012-08-08
Summary
RATIONALE: Prinomastat may stop the growth of non-small cell lung cancer by stopping blood flow to the tumor. Drugs used in chemotherapy stop tumor cells from dividing so they stop growing or die.
PURPOSE: Randomized phase III trial to determine the effectiveness of prinomastat plus cisplatin and gemcitabine in treating patients who have metastatic or recurrent non-small cell lung cancer.
Conditions
Interventions
- DRUG
- DRUG
-
gemcitabine hydrochloride
- DRUG
-
prinomastat
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Mary Collier · Agouron Pharmaceuticals
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1999-03-31
- Primary Completion
- 2001-07-31
Countries
- United States
Study Locations
More Related Trials
-
Study of Paclitaxel, Carboplatin, and Gemcitabine Versus Gemcitabine and Vinorelbine for Non-Small Cell Lung Cancer
NCT00193362 ·Status: COMPLETED ·Phase: PHASE3
-
Carboplatin and Paclitaxel With or Without Vorinostat in Treating Patients With Advanced Non-Small Cell Lung Cancer
NCT01413750 ·Status: TERMINATED ·Phase: PHASE2
-
Satraplatin and Paclitaxel in Patients With Advanced Non-small Cell Lung Cancer
NCT00268970 ·Status: COMPLETED ·Phase: PHASE2
-
Pemetrexed Disodium and Cisplatin in Treating Patients Who Are Undergoing Surgery for Stage I, Stage II, or Stage III Non-Small Cell Lung Cancer
NCT00248495 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Pralsetinib Versus Standard of Care for First-Line Treatment of Advanced Non-Small Cell Lung Cancer (NSCLC)
NCT04222972 ·Status: TERMINATED ·Phase: PHASE3
-
S0119: Combination Chemotherapy in Treating Patients With Extensive-Stage Small Cell Lung Cancer
NCT00030433 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of RO5083945 in Combination With Cisplatin and Gemcitabine or Carboplatin and Paclitaxel in Patients With Advanced or Recurrent Non-Small Cell Lung Cancer of Squamous Histology Who Have Not Received Prior Chemotherapy for The Metastatic Disease
NCT01702714 ·Status: WITHDRAWN ·Phase: PHASE1
-
PR104 in Treating Patients With Previously Untreated or Relapsed Small Cell Lung Cancer
NCT00544674 ·Status: TERMINATED ·Phase: PHASE2
-
Standard Therapy Given With or Without Combination Chemotherapy in Treating Patients With Non-small Cell Lung Cancer
NCT00003240 ·Status: UNKNOWN ·Phase: PHASE3
-
A Study of Onartuzumab (MetMAb) Versus Placebo in Combination With Paclitaxel Plus Platinum in Patients With Squamous Non-Small Cell Lung Cancer
NCT01519804 ·Status: COMPLETED ·Phase: PHASE2
-
Neoadjuvant Chemo for Non-metastatic Non-small Cell Lung Cancer
NCT01860040 ·Status: TERMINATED ·Phase: PHASE2
-
Cisplatin, Etoposide, and Cyclophosphamide in Treating Patients With Extensive-Stage Small Cell Lung Cancer
NCT00083161 ·Status: COMPLETED ·Phase: PHASE2
-
Chemotherapy and Radiation in Treating Participants With Stage 3 Non-Small Cell Lung Cancer
NCT00686959 ·Status: COMPLETED ·Phase: PHASE3
-
Paclitaxel and Oxaliplatin in Treating Patients With Recurrent or Advanced Non-small Cell Lung Cancer
NCT00004126 ·Status: COMPLETED ·Phase: PHASE2
-
Nivolumab and Epacadostat With Platinum Doublet Chemotherapy Versus Platinum Doublet Chemotherapy in Non-Small Cell Lung Cancer
NCT03348904 ·Status: TERMINATED ·Phase: PHASE3
-
Combination Chemotherapy in Treating Patients With Extensive-Stage Small Cell Lung Cancer
NCT00006374 ·Status: WITHDRAWN ·Phase: PHASE2
-
Study of Talabostat and Pemetrexed vs. Pemetrexed in Stage IIIB/IV Non-Small Cell Lung Cancer (NSCLC) After Failure of Platinum-Based Chemotherapy
NCT00290017 ·Status: TERMINATED ·Phase: PHASE3
-
Vinorelbine + Cisplatin or No Further Therapy in Non-small Cell Lung Cancer That Has Been Surgically Removed
NCT00002583 ·Status: COMPLETED ·Phase: PHASE3
-
Combination Chemotherapy, Radiation Therapy, and Gefitinib in Treating Patients With Stage III Non-Small Cell Lung Cancer
NCT00040794 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of RO5083945 in Combination With Chemotherapy Versus Chemotherapy Alone in Patients With Advanced or Recurrent Non-Small Cell Lung Cancer
NCT01185847 ·Status: COMPLETED ·Phase: PHASE2
-
Paclitaxel in Treating Patients With Recurrent or Refractory Non-small Cell Lung Cancer
NCT00004265 ·Status: UNKNOWN ·Phase: PHASE2
-
Phase II Anti-PD1 Epigenetic Therapy Study in NSCLC.
NCT01928576 ·Status: COMPLETED ·Phase: PHASE2
-
Etoposide and Cisplatin or Carboplatin as First-Line Chemotherapy With or Without Pravastatin in Treating Patients With Small Cell Lung Cancer
NCT00433498 ·Status: COMPLETED ·Phase: PHASE3
-
Chemotherapy or Observation in Treating Patients With Early Stage Non-Small Cell Lung Cancer
NCT00863512 ·Status: TERMINATED ·Phase: PHASE3
-
Cisplatin Plus Etoposide With or Without Paclitaxel in Treating Patients With Extensive-Stage Small Cell Lung Cancer
NCT00003299 ·Status: COMPLETED ·Phase: PHASE3