Topotecan in Treating Patients With Recurrent Brain Tumors
NCT00003372 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 17
Last updated 2020-04-08
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.
PURPOSE: Phase II trial to study the effectiveness of topotecan in treating patients with recurrent brain tumor.
Conditions
Interventions
- DRUG
-
topotecan hydrochloride
Sponsors & Collaborators
-
NCIC Clinical Trials Group
lead NETWORK
Principal Investigators
-
Karl Belanger, MD · CHUM - Hotel Dieu Hospital
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 120 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1997-12-08
- Primary Completion
- 2000-10-05
- Completion
- 2009-12-21
Countries
- Canada
Study Locations
More Related Trials
-
Carboplatin Plus Irinotecan in Treating Patients With Glioblastoma Multiforme
NCT00010036 ·Status: COMPLETED ·Phase: PHASE2
-
Irinotecan in Treating Patients With Progressive or Recurrent Malignant Glioma
NCT00003616 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Topotecan and Thalidomide in Treating Patients With Recurrent or Refractory Malignant Glioma
NCT00014443 ·Status: TERMINATED ·Phase: PHASE2
-
Methotrexate and Thiotepa in Treating Patients With Newly Diagnosed Primary CNS Lymphoma
NCT00045539 ·Status: COMPLETED ·Phase: PHASE2
-
Atrasentan in Treating Patients With Progressive or Recurrent Malignant Glioma
NCT00017264 ·Status: COMPLETED ·Phase: PHASE1
-
Gimatecan in Treating Patients With Recurrent or Progressive Primary Malignant Glioma
NCT00087061 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma
NCT06368817 ·Status: RECRUITING ·Phase: PHASE2
-
ATN-161 and Carboplatin in Treating Patients With Recurrent Malignant Glioma
NCT00352313 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Lapatinib in Treating Patients With Recurrent Glioblastoma Multiforme
NCT00099060 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Topotecan by Intracerebral Clysis for Recurrent Primary Malignant Brain Tumors
NCT00308165 ·Status: COMPLETED ·Phase: PHASE1
-
Combination Chemotherapy for Patients With Brain Cancer
NCT00002814 ·Status: COMPLETED ·Phase: PHASE2
-
COL-3 in Treating Patients With Progressive or Recurrent Brain Tumors
NCT00004147 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Irinotecan in Treating Patients With Recurrent Malignant Glioma
NCT00003301 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Procarbazine in Treating Patients With Recurrent Brain Tumor
NCT00004004 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Acridine Carboxamide in Treating Patients With Recurrent Glioblastoma Multiforme
NCT00004937 ·Status: COMPLETED ·Phase: PHASE2
-
Talampanel in Treating Patients With Recurrent High-Grade Glioma
NCT00064363 ·Status: COMPLETED ·Phase: PHASE2
-
Karenitecin in Treating Patients With Recurrent Malignant Glioma
NCT00014521 ·Status: COMPLETED ·Phase: PHASE1
-
Standard Chemotherapy vs. Chemotherapy Guided by Cancer Stem Cell Test in Recurrent Glioblastoma
NCT03632135 ·Status: COMPLETED ·Phase: PHASE3
-
Safety and Tolerability of Carboxyamidotriazole Orotate (CTO) in Solid Tumors or With Temodar® in Glioblastoma or Other Recurrent Malignant Gliomas or in Combination With Temodar® and Radiation Therapy for Patients With Newly Diagnosed Glioblastoma and Malignant Gliomas
NCT01107522 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Anaplastic Astrocytoma
NCT00003621 ·Status: COMPLETED ·Phase: PHASE2
-
Antineoplaston Therapy in Treating Adult Patients With Anaplastic Astrocytoma
NCT00003537 ·Status: COMPLETED ·Phase: PHASE2
-
Radiation Therapy Plus Carboplatin and Lobradimil in Treating Children With Newly Diagnosed Brain Stem Gliomas
NCT00005602 ·Status: COMPLETED ·Phase: PHASE1
-
Combination Chemotherapy and Radiation Therapy in Treating Patients With Germ Cell Tumors in the Brain
NCT00293358 ·Status: COMPLETED ·Phase: PHASE3
-
Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
NCT00003996 ·Status: COMPLETED ·Phase: PHASE2
-
Antineoplaston Therapy in Treating Patients With Brain Tumors
NCT00003457 ·Status: COMPLETED ·Phase: PHASE2