Alanosine in Treating Patients With Progressive or Recurrent Malignant Gliomas
NCT00075894 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 18
Last updated 2009-01-13
Summary
RATIONALE: Drugs used in chemotherapy, such as alanosine, use different ways to stop tumor cells from dividing so they stop growing or die.
PURPOSE: This phase I trial is studying the side effects and best dose of alanosine in treating patients with high-grade progressive or recurrent malignant gliomas.
Conditions
Interventions
- DRUG
-
L-alanosine
Sponsors & Collaborators
-
National Cancer Institute (NCI)
lead NIH
Principal Investigators
-
Surasak Phuphanich, MD, FAAN · Emory University
Study Design
- Purpose
- TREATMENT
- Masking
- NONE
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2004-03-31
Countries
- United States
Study Locations
More Related Trials
-
Procarbazine in Treating Patients With Recurrent Brain Tumor
NCT00004004 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Atrasentan in Treating Patients With Progressive or Recurrent Malignant Glioma
NCT00017264 ·Status: COMPLETED ·Phase: PHASE1
-
Phosphorus 32 in Treating Patients With Glioblastoma Multiforme
NCT00004129 ·Status: UNKNOWN ·Phase: PHASE1
-
Sorafenib in Treating Patients With Recurrent or Progressive Malignant Glioma
NCT00093613 ·Status: COMPLETED ·Phase: PHASE1
-
Expanded Access to ANG1005 for Individual Patients
NCT02755987 ·Status: NO_LONGER_AVAILABLE
-
TRC105 for Recurrent Glioblastoma
NCT01778530 ·Status: TERMINATED ·Phase: PHASE2
-
Pyrazoloacridine Plus Carboplatin in Treating Patients With Recurrent Glioma
NCT00005976 ·Status: COMPLETED ·Phase: PHASE2
-
Antineoplaston Therapy in Treating Patients With Primary Malignant Brain Tumors
NCT00003475 ·Status: COMPLETED ·Phase: PHASE2
-
Oxaliplatin in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
NCT00005856 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
CC-8490 in Treating Patients With Recurrent or Refractory High-Grade Gliomas
NCT00074243 ·Status: COMPLETED ·Phase: PHASE1
-
Antineoplaston Therapy in Treating Patients With Low-Grade Astrocytoma
NCT00003471 ·Status: TERMINATED ·Phase: PHASE2
-
Irinotecan in Treating Patients With Recurrent Glioma
NCT00003134 ·Status: COMPLETED ·Phase: PHASE2
-
Carmustine Plus O(6)-Benzylguanine in Treating Patients With Recurrent or Progressive Gliomas of the Brain
NCT00003348 ·Status: COMPLETED ·Phase: PHASE1
-
Antineoplaston Therapy in Treating Adults With Residual/Recurrent/Progressive Glioblastoma Multiforme
NCT00003474 ·Status: COMPLETED ·Phase: PHASE2
-
Safety Study of AP23573 in Patients With Progressive or Recurrent Glioma (8669-023)(COMPLETED)
NCT00087451 ·Status: COMPLETED ·Phase: PHASE1
-
Antineoplaston Therapy in Treating Adult Patients With Anaplastic Astrocytoma
NCT00003537 ·Status: COMPLETED ·Phase: PHASE2
-
Antineoplaston Therapy in Treating Patients With Recurrent or Refractory Oligodendroglioma
NCT00003472 ·Status: TERMINATED ·Phase: PHASE2
-
Antineoplaston Therapy in Treating Patients With Metastatic, Recurrent, or Refractory Primitive Neuroectodermal Tumors
NCT00003515 ·Status: TERMINATED ·Phase: PHASE2
-
A Phase I/II Trial of BMS-247550 for Treatment of Patients With Recurrent High-Grade Gliomas
NCT00045708 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma
NCT04166409 ·Status: RECRUITING ·Phase: PHASE3
-
Irinotecan Plus Carmustine in Treating Patients With Recurrent Primary Malignant Glioma
NCT00002988 ·Status: COMPLETED ·Phase: PHASE1
-
AMG 595 First-in-Human in Recurrent Gliomas
NCT01475006 ·Status: COMPLETED ·Phase: PHASE1
-
Antineoplaston Therapy in Treating Children With Recurrent or Refractory High-Grade Glioma
NCT00003535 ·Status: TERMINATED ·Phase: PHASE2
-
Irinotecan in Treating Patients With Progressive or Recurrent Malignant Glioma
NCT00003616 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Clinical and Molecular-Metabolic Phase II Trial of Perifosine for Recurrent/Progressive Malignant Gliomas
NCT00590954 ·Status: COMPLETED ·Phase: PHASE2