Combination Chemotherapy in Treating Patients With Advanced Non-small Cell Lung Cancer
NCT00003589 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 450
Last updated 2012-03-06
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known which combination chemotherapy regimen is more effective in treating advanced non-small cell lung cancer.
PURPOSE: Randomized phase III trial to compare the effectiveness of three different combination chemotherapy regimens in treating patients who have advanced non-small cell lung cancer.
Conditions
Interventions
- DRUG
- DRUG
-
gemcitabine hydrochloride
- DRUG
Sponsors & Collaborators
-
European Organisation for Research and Treatment of Cancer - EORTC
lead NETWORK
Principal Investigators
-
Egbert F. Smit, MD · Free University Medical Center
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1998-08-31
- Primary Completion
- 2000-07-31
Countries
- Belgium
- Czechia
- Egypt
- France
- Germany
- Greece
- Italy
- Netherlands
- Poland
- South Africa
- Spain
- Switzerland
Study Locations
More Related Trials
-
Gemcitabine Plus Radiation Therapy or Combination Chemotherapy in Treating Patients With Non-small Cell Lung Cancer
NCT00003202 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Chemotherapy in Treating Patients With Cancer of Unknown Primary Origin
NCT00003558 ·Status: UNKNOWN ·Phase: PHASE3
-
Oxaliplatin and Gemcitabine in Treating Patients With Advanced Cancer
NCT00004220 ·Status: COMPLETED ·Phase: PHASE1
-
Hospitalization Rates of Patients With Non-Small Cell Lung Cancer Treated With Gemcitabine and Either Cisplatin or Carboplatin
NCT00055965 ·Status: UNKNOWN ·Phase: PHASE3
-
Surgery, Gemcitabine, Cisplatin, and Radiation Therapy in Treating Patients With Stage II or Stage III Non-Small Cell Lung Cancer
NCT00530634 ·Status: TERMINATED ·Phase: PHASE2
-
Gemcitabine Hydrochloride or Pemetrexed Disodium and Carboplatin With or Without Celecoxib in Treating Patients With Advanced Non-Small Cell Lung Cancer
NCT01041781 ·Status: TERMINATED ·Phase: PHASE3
-
Combination Chemotherapy in Treating Patients With Advanced Solid Tumors
NCT00004913 ·Status: COMPLETED ·Phase: PHASE1
-
Carboplatin and Gemcitabine in Treating Patients With Advanced Solid Tumors
NCT00021346 ·Status: COMPLETED ·Phase: PHASE1
-
A Study With Gemcitabine, Cisplatin, and LY293111 in Non-Small Cell Lung Cancer
NCT00069875 ·Status: COMPLETED ·Phase: PHASE2
-
Multicenter Phase 2 Trial Evaluating Cisplatin-Gemcitabine With Concomitant Thoracic Radiotherapy for Treatment of Inoperable Stage III Non Small Cell Lung Cancer
NCT00192036 ·Status: COMPLETED ·Phase: PHASE2
-
Gemcitabine Plus Flavopiridol in Treating Patients With Advanced Solid Tumors
NCT00007917 ·Status: COMPLETED ·Phase: PHASE1
-
Combination Chemotherapy in Treating Patients With Locally Advanced or Metastatic Solid Tumors
NCT00003742 ·Status: COMPLETED ·Phase: PHASE1
-
Combination Chemotherapy in Treating Patients With Advanced Solid Tumors
NCT00005819 ·Status: COMPLETED ·Phase: PHASE1
-
Combination Chemotherapy in Treating Patients With Locally Advanced or Metastatic Solid Tumors
NCT00005791 ·Status: COMPLETED ·Phase: PHASE1
-
Gemcitabine in Treating Patients With Recurrent or Metastatic Adenoid Cystic Cancer of the Head and Neck
NCT00017498 ·Status: COMPLETED ·Phase: PHASE2
-
Gemcitabine Plus Carboplatin or Cisplatin in Treating Patients With Stage IIIB, Stage IV, or Recurrent Non-small Cell Lung Cancer
NCT00004201 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy in Treating Patients With Refractory or Recurrent Solid Tumors
NCT00003004 ·Status: COMPLETED ·Phase: PHASE1
-
Trial of Perioperative Chemotherapy (Gemcitabine and Cisplatin) and Adjuvant Chemoradiotherapy (With Weekly Low Dose Gemcitabine) in Patients With Lung Cancer With Positive Nodes
NCT00490659 ·Status: COMPLETED ·Phase: PHASE2
-
Cisplatin Plus Gemcitabine With or Without Paclitaxel in Treating Patients With Stage IV Urinary Tract Cancer
NCT00022191 ·Status: COMPLETED ·Phase: PHASE3
-
Evaluation of Carboplatin Plus Gemcitabine Followed by Concomitant Chemoradiation for Non-resectable Stage III NSCLC
NCT00463515 ·Status: COMPLETED ·Phase: PHASE2
-
Chemotherapy With Pemetrexed in Combination With Platinum for Advanced Non-Small Cell Lung Cancer (NSCLC)
NCT00402051 ·Status: COMPLETED ·Phase: PHASE2
-
Cilengitide and Cetuximab in Combination With Platinum-based Chemotherapy as First-line Treatment for Subjects With Advanced Non Small Cell Lung Cancer (NSCLC)
NCT00842712 ·Status: COMPLETED ·Phase: PHASE2
-
Carboplatin and Gemcitabine in Treating Patients With Locally Advanced or Metastatic Breast Cancer
NCT00470249 ·Status: TERMINATED ·Phase: PHASE2
-
Tanespimycin, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Advanced Solid Tumors
NCT00047047 ·Status: COMPLETED ·Phase: PHASE1
-
Bortezomib and Combination Chemotherapy in Treating Patients With Advanced Solid Tumors
NCT00027898 ·Status: COMPLETED ·Phase: PHASE1