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Carboplatin and Gemcitabine in Treating Patients With Locally Advanced or Metastatic Breast Cancer

NCT00470249 · Status: TERMINATED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 5

Last updated 2021-02-01

No results posted yet for this study

Summary

RATIONALE: Drugs used in chemotherapy, such as carboplatin and gemcitabine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells.

PURPOSE: This phase II trial is studying how well giving carboplatin together with gemcitabine works in treating patients with locally advanced or metastatic breast cancer.

Conditions

Interventions

DRUG

Carboplatin

At a dose equivalent to an area under the concentration-time curve of 4.5 mg/ml.min on day 1 of every 2-week cycle

DRUG

Gemcitabine Hydrochloride

1500 mg/m2 on day 2 of every 2-week cycle

Sponsors & Collaborators

  • University of Southampton

    lead OTHER

Principal Investigators

  • Nicholas Murray, MD · University Hospital Southampton NHS Foundation Trust

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
120 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2006-07-15
Primary Completion
2008-11-03
Completion
2008-11-03

Countries

  • United Kingdom

Study Locations

More Related Trials

Entities

Drugs
Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00470249 on ClinicalTrials.gov