Monoclonal Antibody Therapy in Treating Patients With Leptomeningeal Cancer
NCT00003022 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL
Last updated 2013-07-03
Summary
RATIONALE: Monoclonal antibodies can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells.
PURPOSE: Phase I trial to study the effectiveness of monoclonal antibody therapy in treating patients who have leptomeningeal metastases.
Conditions
- Brain and Central Nervous System Tumors
- Intraocular Melanoma
- Lung Cancer
- Melanoma (Skin)
- Neuroblastoma
- Retinoblastoma
- Sarcoma
Interventions
- RADIATION
-
iodine I 131 monoclonal antibody 3F8
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Memorial Sloan Kettering Cancer Center
lead OTHER
Principal Investigators
-
Kim Kramer, MD · Memorial Sloan Kettering Cancer Center
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 3 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1997-04-30
- Primary Completion
- 2005-01-31
- Completion
- 2005-01-31
Countries
- United States
Study Locations
More Related Trials
-
Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Melanoma or Brain Tumors
NCT00002754 ·Status: COMPLETED ·Phase: PHASE1
-
LMB-7 Immunotoxin in Treating Patients With Leptomeningeal Metastases
NCT00003020 ·Status: COMPLETED ·Phase: PHASE1
-
Safety Study of 188Re-PTI-6D2 in Patients With Metastatic Melanoma
NCT00399113 ·Status: COMPLETED ·Phase: PHASE1
-
Lymphodepletion Plus Adoptive Cell Transfer With or Without Dendritic Cell Immunization in Patients With Metastatic Melanoma
NCT00338377 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Monoclonal Antibody Therapy in Treating Patients With Advanced Kidney Cancer
NCT00003102 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Biological Therapy in Treating Patients With Neuroblastoma That Has Not Responded to Previous Treatment
NCT00089258 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of GNC-039, a Tetra-specific Antibody, in Participants With Relapsed/Refractory or Metastatic Solid Tumors
NCT04794972 ·Status: RECRUITING ·Phase: PHASE1
-
Radiation, Chemotherapy, Vaccine and Anti-MART-1 and Anti-gp100 Cells for Patients With Metastatic Melanoma
NCT00923195 ·Status: COMPLETED ·Phase: PHASE2
-
Monoclonal Antibody and Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma That Has Been Removed During Surgery
NCT00025181 ·Status: COMPLETED ·Phase: PHASE1
-
Natural Killer Cell Therapy (UD TGFbetai NK Cells) and Temozolomide for the Treatment of Stage IV Melanoma Metastatic to the Brain
NCT05588453 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Monoclonal Antibody With or Without gp100 Peptides Plus Montanide ISA-51 in Treating Patients With Stage IV Melanoma
NCT00077532 ·Status: COMPLETED ·Phase: PHASE2
-
Vaccine Therapy in Treating Patients With Metastatic Melanoma
NCT00003792 ·Status: COMPLETED ·Phase: PHASE1
-
Monoclonal Antibody Therapy in Treating Patients With Refractory Advanced Solid Tumors or Lymphoma
NCT00049712 ·Status: COMPLETED ·Phase: PHASE1
-
SRS and Nivolumab in Treating Patients With Newly Diagnosed Melanoma Metastases in the Brain or Spine
NCT02716948 ·Status: COMPLETED ·Phase: PHASE1
-
Vaccine Therapy in Treating Patients With Metastatic Melanoma
NCT00334776 ·Status: COMPLETED ·Phase: PHASE2
-
Monoclonal Antibody 3F8 and Sargramostim in Treating Patients With Neuroblastoma
NCT00072358 ·Status: COMPLETED ·Phase: PHASE2
-
Monoclonal Antibody Therapy in Treating Patients With Advanced Solid Tumors
NCT00052403 ·Status: WITHDRAWN ·Phase: PHASE1
-
Vaccine Therapy in Treating Patients With Metastatic Melanoma of the Eye
NCT00020475 ·Status: COMPLETED ·Phase: PHASE2
-
Interleukin-7 and Vaccine Therapy in Treating Patients With Metastatic Melanoma
NCT00091338 ·Status: COMPLETED ·Phase: PHASE1
-
GD2-SADA:177Lu-DOTA Complex in Patients With Solid Tumors Known to Express GD2
NCT05130255 ·Status: RECRUITING ·Phase: PHASE1
-
Vaccine Therapy With or Without Interleukin-2 in Treating Patients With Metastatic Melanoma
NCT00019448 ·Status: COMPLETED ·Phase: PHASE2
-
Peptide Vaccination for Patients at High Risk for Recurrent Melanoma
NCT00059475 ·Status: COMPLETED ·Phase: PHASE2
-
Monoclonal Antibody Therapy and Interleukin-2 in Treating Patients With Metastatic Melanoma
NCT00058279 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
QUILT-3.046: NANT Melanoma Vaccine: Combination Immunotherapy in Subjects With Melanoma Who Have Progressed On or After Chemotherapy and PD-1/PD-L1 Therapy
NCT03167177 ·Status: WITHDRAWN ·Phase: PHASE1/PHASE2
-
Lymphocyte Re-infusion During Immune Suppression to Treat Metastatic Melanoma
NCT00001832 ·Status: COMPLETED ·Phase: PHASE2