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The Impact of Familiarity and Emotional Attachment on the Visual Processing of Faces

NCT00001913 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 80

Last updated 2008-03-04

No results posted yet for this study

Summary

This study uses functional magnetic resonance imaging (fMRI) to look at brain activity while patients view pictures of people's faces that they are familiar with or have emotional attachment to.

The functional MRI (fMRI) procedure allows researchers to "see the brain at work." It uses the same powerful magnetic fields and weak electromagnetic radiation (radiowaves) as standard structural MRI. However, functional MRI can also show areas of increased blood flow, which relates to increased activity by brain cells.

This research study builds on previous studies that identified specific areas of the brain that are activated by visual stimuli showing faces. However, previous research used anonymous faces as stimuli. This study will use faces of individuals known to the patient.

There are three experiments that will be conducted in the study;

1. Experiment 1 will attempt to determine the effects of familiarity of the photographed face on brain activity patterns. Patients will view familiar faces, the faces of close friends and relatives, and the faces of famous people.
2. Experiment 2 will look at how maternal attachment affects the response to visual stimuli. Mothers will view pictures of their first born child, as well as those of familiar children to whom they are not related, unfamiliar children, and unfamiliar adults.
3. Experiment 3 will explore the effects of interpersonal attachment and loss on response to visual stimuli. In this experiment, bereaved spouses will view pictures of their deceased spouse, those of living family members, and those of unfamiliar people.

Conditions

  • Bereavement
  • Healthy

Sponsors & Collaborators

  • National Institute of Mental Health (NIMH)

    lead NIH

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
1998-10-31
Completion
2003-10-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00001913 on ClinicalTrials.gov