Cholesterol Reduction in Seniors Program (CRISP)
NCT00000477 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2016-02-18
Summary
To conduct a pilot study to determine whether lowering elevated serum cholesterol levels with 3-hydroxy-3-methyl-glutaryl coenzyme A (HMG CoA) reductase inhibitors reduced mortality due to the sequelae of atherosclerotic cardiovascular disease in older men and women.
Conditions
- Atherosclerosis
- Cardiovascular Diseases
- Coronary Disease
- Heart Diseases
- Hypercholesterolemia
- Myocardial Ischemia
Interventions
- DRUG
-
lovastatin
Sponsors & Collaborators
-
National Heart, Lung, and Blood Institute (NHLBI)
lead NIH
Principal Investigators
-
William Applegate · University of Tennessee
-
John Crouse · Bowman Gray School of Medicine
-
Donald Hunninghake · University of Minnesota
-
Robert Knopp · University of Washington
-
John LaRosa · George Washington University
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
Eligibility
- Min Age
- 65 Years
- Max Age
- 100 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1990-07-31
- Completion
- 1992-06-30
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