News Related to Heart Failure

Related coverage linked through entity extraction aliases.

Novartis Q2 2026: Entresto Sales Plunge 50%, Pipeline Advances, and Plant Closure

Jul 21, 2026

Novartis posted Q2 2026 earnings above expectations but a 50% drop in Entresto sales from U.S. generics hurt performance. The company highlighted new EU and Japan approvals for Rhapsido and Itvisma, and a manufacturing restructuring including a German plant closure and investment in radioligand production. A $1.8 billion peptide drug pact with Unnatural Products was also announced.

Cardiol Therapeutics Publishes Phase II Recurrent Pericarditis Data in JAHA

Jul 14, 2026

Cardiol Therapeutics announced the publication of its Phase II MAvERIC study results in the Journal of the American Heart Association. The study showed CardiolRx led to rapid and sustained reductions in pericarditis pain and inflammation with a favorable safety profile. The findings support the ongoing Phase III MAVERIC trial.

Japan's Regenerative Cell Therapy Push Advances With Regulatory Review, Market Growth, and New Patents

Jun 11, 2026

Japan's health ministry panel is reviewing two regenerative cell therapies for Parkinson's disease and heart failure, testing the country's push to build a domestic cell-based treatment industry. Japan's cell culture market is projected to reach USD 2.34 billion by 2031, driven by government support and favorable regulatory pathways. Australian firm Cartherics secured a Japanese patent for its iPSC-based immune cell therapies.

CVRx enrolls first patient in BENEFIT-HF heart failure trial

May 05, 2026

CVRx announced first-patient enrollment in the BENEFIT-HF trial, a 2,500-patient heart failure study across about 150 U.S. and German centers. The trial will evaluate all-cause mortality and heart failure decompensation events through 2032.