Heart disease is an umbrella term for multiple heart conditions, most commonly coronary artery disease. It remains a leading cause of death and includes conditions that may present with heart attack, arrhythmia, or heart failure events. Major modifiable risks include hypertension, high cholesterol, and smoking.
New research advances canine heart disease care: a breath test could detect heart disease earlier in dogs, and the minimally invasive M-TEER procedure is being adapted from humans to treat mitral regurgitation in dogs.
Alnylam reported Q4 2025 adjusted EPS of $1.25, beating estimates, while revenue of $1.10 billion missed consensus despite 85% growth. Amvuttra sales surged 189% to $826.6 million. The stock fell 4.1% after the mixed results.
UK data links 150+ deaths to weight-loss jabs. A new study finds a vegan diet led to 5.9kg average loss in 4 months vs 6.9kg over 9 months for semaglutide.
A 64-year-old Australian man was diagnosed with stage 3 breast cancer after his wife noticed bloodstains on his shirt, a case doctors say highlights that men can and do get the disease. Meanwhile, advances in precision medicine now allow breast cancer treatment to be tailored to each tumour’s biology and the patient’s overall health.
AI is transforming cardiovascular medicine: $1.4B+ in investments, a new cardiac biomarker sensor, and stroke-imaging software in 2,500+ hospitals. FDA, EMA, and PMDA are opening clearer regulatory pathways.
Anthropic announced it will run its own preclinical drug-discovery programs for neglected and rare diseases and launched Claude Science, an AI workbench for researchers. The company has not named specific diseases or detailed how it would bring candidates to market.
NICE updates type 2 diabetes guidance in England, recommending earlier use of SGLT-2 inhibitors and GLP-1 receptor agonists. Separately, a study finds SGLT2 inhibitors improve survival in Takotsubo syndrome patients.
Alnylam Pharmaceuticals entered a $1.23 billion discovery collaboration with Tenaya Therapeutics to identify up to 15 novel genetic targets for heart disease. The agreement includes $10 million upfront and up to $1.13 billion in milestone payments.
More cancer survivors are living long enough to face lasting cardiovascular effects of treatment. Cardio-oncology clinics are managing heart failure, valvular disease and radiation-related heart disease.
Vermont insurers and employers are scaling back GLP-1 coverage as costs rise, leaving some patients without access. The drugs remain in high demand as studies point to benefits beyond weight loss.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07770269 |
Assessment of Cardiac Function and Anesthesia Depth in Patients Undergoing Cardiac Surgery |
RECRUITING | NA |
| NCT07747207 |
PULSTA TPV Observational Study |
NOT_YET_RECRUITING | |
| NCT07736066 |
Remote ECG Monitoring-Based Phase I Cardiac Rehabilitation After Heart Surgery |
COMPLETED | NA |
| NCT07591792 |
Outpatient Rehabilitation Programmes for Myocardial Ischemia, Heart Failure, and COPD: Satisfaction, Participation, Test Outcomes, and Factors Associated With Positive Changes in Test Results as Well as Level of Participation |
NOT_YET_RECRUITING | |
| NCT07558109 |
DigitHeart Echo Study |
RECRUITING | |
| NCT07502703 |
Validation of Remote Photoplethysmography (rPPG)-Derived Cardiovascular Parameters Against Standard Clinical Measurements and Risk Scores in a Community |
NOT_YET_RECRUITING | |
| NCT07485738 |
The Relationship Between Blood Flow Readings During Surgery and How Well the Graft Stays Open and How Patients Recover Afterward in Coronary Artery Bypass Graft Surgery |
RECRUITING | NA |
| NCT07416279 |
Can Tiny Bubbles Offer an Alternative to Catheters for Assessing Pressures Inside the Heart? Investigating Ultrasound Contrast Agents as Pressure Sensors Against Gold Standard Catheter Pressures in Cardiac Catheterisation Patients. |
RECRUITING | NA |
| NCT07407816 |
Feasibility Study of the Supira System in Patients Undergoing HRPCI With Support Beyond the PCI Procedure |
RECRUITING | NA |
| NCT07388355 |
A Usability Study of a Multi-channel ECG Monitoring Device |
RECRUITING | NA |
