NCT05668741 A Phase 1/2 Study of VX-522 in Participants With Cystic Fibrosis (CF) Status ACTIVE_NOT_RECRUITING Phase PHASE1/PHASE2
NCT05661734 A Single-arm Study to Evaluate Safety and Effectiveness of VX-548 for Acute Pain Status COMPLETED Phase PHASE3
NCT05660538 Evaluation of Efficacy and Safety of VX-548 for Painful Diabetic Peripheral Neuropathy (DPN) Status COMPLETED Phase PHASE2
NCT05653323 A Phase 1 Dose Escalation Study of VX-993 in Healthy Participants Status COMPLETED Phase PHASE1
NCT05643495 A Study to Evaluate Efficacy and Safety of VX-864 in Participants With the PiZZ Genotype Status TERMINATED Phase PHASE2
NCT05635110 Evaluation of the Effects of Omeprazole and Rifampin on the Pharmacokinetics of VX-548 in Healthy Participants Status COMPLETED Phase PHASE1
NCT05560464 Evaluation of the Pharmacokinetics and Safety of VX-548 in Participants With Mild or Moderate Hepatic Impairment Status COMPLETED Phase PHASE1
NCT05558410 Evaluation of Efficacy and Safety of Suzetrigine for Acute Pain After an Abdominoplasty Status COMPLETED Phase PHASE3
NCT05553366 Evaluation of Efficacy and Safety of VX-548 for Acute Pain After a Bunionectomy Status COMPLETED Phase PHASE3
NCT05541471 A Study to Evaluate the Pharmacokinetic Drug-drug Interactions Between VX-548, Midazolam, and Digoxin Status COMPLETED Phase PHASE1
NCT05535959 A Study to Evaluate the Relative Bioavailability of a Fixed-dose Combination Tablet of VX-121/Tezacaftor/Deutivacaftor Status COMPLETED Phase PHASE1
NCT05518734 A Phase 1 Dose Escalation Study of VX-708 in Healthy Participants Status COMPLETED Phase PHASE1
NCT05477563 Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease Status RECRUITING Phase PHASE3
NCT05455502 A Study to Evaluate the Relative Bioavailability and Food Effect of a New Tablet Formulation of VX-548 Status COMPLETED Phase PHASE1
NCT05444257 A Study Evaluating the Long-term Safety and Efficacy of VX-121 Combination Therapy Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT05437120 Pharmacokinetics and Safety Assessment of VX-121/Tezacaftor/Deutivacaftor in Participants With Moderate Hepatic Impairment Status COMPLETED Phase PHASE1
NCT05422222 Evaluation of VX-121/Tezacaftor/Deutivacaftor in Cystic Fibrosis (CF) Participants 1 Through 11 Years of Age Status RECRUITING Phase PHASE3
NCT05418712 A Microneurography (MNG) Study of VX-150 in Healthy Participants Status COMPLETED Phase PHASE1
NCT05356195 Evaluation of Safety and Efficacy of CTX001 in Pediatric Participants With Transfusion-Dependent β-Thalassemia (TDT) Status ACTIVE_NOT_RECRUITING Phase PHASE3