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A Phase 1 Dose Escalation Study of VX-708 in Healthy Participants

NCT05518734 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 64

Last updated 2023-03-30

No results posted yet for this study

Summary

The purpose of this study is to evaluate the safety, pharmacokinetics, and pharmacodynamics of multiple ascending doses of VX-708 in healthy participants

Conditions

Interventions

DRUG

VX-708

Solution for intravenous (IV) administration.

DRUG

Itraconazole

Solution for oral administration.

DRUG

Midazolam

Solution for oral administration.

DRUG

Placebo

Placebo matched to VX-708 for IV administration.

Sponsors & Collaborators

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
SEQUENTIAL

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-09-17
Primary Completion
2023-03-07
Completion
2023-03-07
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs
Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05518734 on ClinicalTrials.gov