A Phase 1 Dose Escalation Study of Oral VX-708 in Healthy Participants
- Status
- COMPLETED
- Phase
- PHASE1
Clinical Trials Related to Vertex Pharmaceuticals Incorporated
Related studies linked through entity extraction aliases.
Study to Evaluate Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA) Long-term Safety and Efficacy in Subjects Without F508del
- Status
- ACTIVE_NOT_RECRUITING
- Phase
- PHASE3
Evaluation of Safety and Efficacy of CTX001 in Pediatric Participants With Severe Sickle Cell Disease (SCD)
- Status
- ACTIVE_NOT_RECRUITING
- Phase
- PHASE3
A Phase 1 Dose Escalation Study to Evaluate Safety and Pharmacokinetics (PK) of VX-840 in Healthy Participants
- Status
- COMPLETED
- Phase
- PHASE1
Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease
- Status
- RECRUITING
- Phase
- PHASE2/PHASE3
Evaluation of Efficacy and Safety of Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA) in Cystic Fibrosis Subjects Without an F508del Mutation
- Status
- COMPLETED
- Phase
- PHASE3
Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA in Cystic Fibrosis (CF) Participants 2 Years and Older
- Status
- COMPLETED
- Phase
- PHASE3
A Study Evaluating the Safety of Elexacaftor/Tezacaftor/Ivacaftor in Participants With Cystic Fibrosis (CF)
- Status
- COMPLETED
- Phase
- PHASE3
A Study of VX-121 Combination Therapy in Participants With Cystic Fibrosis (CF) Who Are Homozygous for F508del, Heterozygous for F508del and a Gating (F/G) or Residual Function (F/RF) Mutation, or Have At Least 1 Other Triple Combination Responsive (TCR) CFTR Mutation and No F508del Mutation
- Status
- COMPLETED
- Phase
- PHASE3
A Study Evaluating Efficacy and Safety of VX-548 for Acute Pain After an Abdominoplasty
- Status
- COMPLETED
- Phase
- PHASE2
A Phase 3 Study of VX-121 Combination Therapy in Participants With Cystic Fibrosis (CF) Heterozygous for F508del and a Minimal Function Mutation (F/MF)
- Status
- COMPLETED
- Phase
- PHASE3
A Study Evaluating Efficacy and Safety of VX-548 for Acute Pain After a Bunionectomy
- Status
- COMPLETED
- Phase
- PHASE2
A Study to Evaluate ELX/TEZ/IVA on Cough and Physical Activity in Participants With Cystic Fibrosis (CF)
- Status
- COMPLETED
- Phase
- PHASE3
A Decentralized Study to Evaluate Physical Activity and Cough Frequency Using Wearable Technology in Cystic Fibrosis
- Status
- COMPLETED
- Phase
- N/A
A Safety, Tolerability, and Efficacy Study of VX-880 in Participants With Type 1 Diabetes
- Status
- RECRUITING
- Phase
- PHASE3
ELX/TEZ/IVA Expanded Access Program for Cystic Fibrosis (CF) Patients With at Least One F508del Mutation
- Status
- APPROVED_FOR_MARKETING
- Phase
- N/A
Gut Imaging for Function & Transit in CF - GIFT-CF 3
- Status
- COMPLETED
- Phase
- N/A
A Study to Assess the Effect of ELX/TEZ/IVA on Glucose Tolerance in Participants With Cystic Fibrosis (CF)
- Status
- COMPLETED
- Phase
- PHASE3
A Study Evaluating the Long-term Safety and Efficacy of Elexacaftor/Tezacaftor/Ivacaftor in Cystic Fibrosis (CF) Particpants 6 Years and Older and F/MF Genotypes
- Status
- COMPLETED
- Phase
- PHASE3
Evaluation of ELX/TEZ/IVA in Cystic Fibrosis (CF) Subjects 2 Through 5 Years
- Status
- COMPLETED
- Phase
- PHASE3