Clinical Trials

NCT07061977 | RECRUITING | PHASE3

336 participants

Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2025-11-05

Completion:

2030-12-31

Conditions

• Locally Advanced Cervical Adenocarcinoma
• Locally Advanced Cervical Adenosquamous Carcinoma
• Locally Advanced Cervical Squamous Cell Carcinoma
• Stage IIIA Cervical Cancer FIGO 2018
• Stage IIIB Cervical Cancer FIGO 2018
• Stage IIIC1 Cervical Cancer FIGO 2018
• Stage IIIC2 Cervical Cancer FIGO 2018
• Stage IVA Cervical Cancer FIGO 2018

Interventions

• PROCEDURE
• RADIATION
• DRUG
• BIOLOGICAL

No Results Yet

NCT07059091 | RECRUITING | PHASE2

334 participants

Clinical Trial of Omalizumab for Allergen Sensitized and Exposed Individuals With COPD

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2026-02-12

Completion:

2031-01-31

Conditions

• Chronic Obstructive Pulmonary Disease (COPD)
• Allergies

Interventions

• DRUG

No Results Yet

NCT07057687 | ACTIVE_NOT_RECRUITING | NA

45 participants

Non-Specific Chronic Low Back Pain Treatment Methods

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2024-09-02

Completion:

2026-06-02

Conditions

• Non-Specific Chronic Low Back Pain

Interventions

• OTHER

No Results Yet

NCT07055282 | RECRUITING | EARLY_PHASE1

32 participants

SGLT2i in Kidney Stones

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2025-11-20

Completion:

2028-11-01

Conditions

• Kidney Stones

Interventions

• DRUG

No Results Yet

NCT07053787 | NOT_YET_RECRUITING | NA

176 participants

Durability of Yoga for Veterans With Low Back Pain

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2026-11-01

Completion:

2031-06-30

Conditions

• Chronic Low Back Pain

Interventions

• BEHAVIORAL

No Results Yet

NCT07048197 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

27 participants

A Study to Assess Safety, Cellular Kinetics and Exploratory Efficacy of Rapcabtagene Autoleucel in Rheumatoid Arthritis and Sjogren's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2025-06-20

Completion:

2028-11-01

Conditions

• Rheumatoid Arthritis (RA) and Sjögren's Disease (SjD)

Interventions

• BIOLOGICAL

No Results Yet

NCT07042009 | RECRUITING | NA

60 participants

Effectiveness of Nutritional Resources for Milk Donors

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2026-04-02

Completion:

2027-02-11

Conditions

• Docosahexaenoic Acid Content of the Participants
• Docosahexaenoic Acid Content of the Breast Milk

Interventions

• OTHER

No Results Yet

NCT07041242 | RECRUITING

164 participants

Outcomes and Complication Rates of Anterior Cruciate Ligament Reconstruction Using the "Over-the-top" Technique Combined With Lateral Extra-articular Tenodesis in Patients Over 50 Years Old, Compared With a Control Group of Patients Under 30

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-04

Start Date:

2025-07-13

Completion:

2027-06-30

Conditions

• ACL
• LET
• Hamstring Muscles

Interventions

• PROCEDURE

No Results Yet

NCT07040137 | ACTIVE_NOT_RECRUITING | PHASE3

142 participants

Confirmatory Study 3 of KPS-0373 in Patients With Spinocerebellar Degeneration

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2025-08-15

Completion:

2027-03-31

Conditions

• Spinocerebellar Degeneration

Interventions

• DRUG

No Results Yet

NCT07038343 | RECRUITING | PHASE1/PHASE2

480 participants

AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2025-06-04

Completion:

2030-06-30

Conditions

• Solid Tumor Cancer
• Locally Advanced
• Metastatic Solid Tumors
• Lung Cancers
• Epithelial Tumor
• Biliary Tract Cancer (BTC)
• Urothelial Cancer
• Nasopharyngeal Cancers

Interventions

• DRUG

No Results Yet

NCT07029698 | COMPLETED | PHASE4

46 participants

A Study to See if a Combination of Vitamins That is Injected Into a Muscle is as Good and Safe as a Vitamin That is Taken by Mouth

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2025-04-16

Completion:

2025-10-07

Conditions

• Vitamin B12 Deficiency

Interventions

• DRUG

No Results Yet

NCT07027826 | RECRUITING | NA

70 participants

The Esophageal String Test as a Diagnostic Screening Tool for Eosinophilic Esophagitis Among Africans With Dysphagia in Mali and the United States

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2026-09-09

Completion:

2027-08-31

Conditions

• Dysphagia
• Eosinophilic Esophagitis

Interventions

• DEVICE

No Results Yet

NCT07023354 | RECRUITING | PHASE1

32 participants

A Study to Test How BI 1291583 is Taken up in the Blood of People With and Without Liver Problems

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2025-07-17

Completion:

2026-12-23

Conditions

• Healthy
• Hepatic Impairment

Interventions

• DRUG

No Results Yet

NCT07022678 | RECRUITING | PHASE3

556 participants

Xylitol Dental Wipes for the Reduction of Bloodstream Infection Risk in Children With Acute Myeloid Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2026-08-14

Completion:

2032-01-15

Conditions

• Acute Myeloid Leukemia
• Recurrent Acute Myeloid Leukemia

Interventions

• OTHER
• PROCEDURE
• DRUG

No Results Yet

NCT07021183 | RECRUITING | NA

60 participants

The PSP Sleep Course: An Online Sleep Intervention for Public Safety Personnel With Self-reported Sleep Difficulties.

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2025-03-06

Completion:

2028-03-31

Conditions

• Insomnia

Interventions

• BEHAVIORAL

No Results Yet

NCT07012031 | RECRUITING | PHASE1/PHASE2

37 participants

Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2026-06-17

Completion:

2027-06-14

Conditions

• Locally Advanced Lung Non-Small Cell Carcinoma
• Metastatic Lung Non-Small Cell Carcinoma
• Stage III Lung Cancer AJCC v8
• Stage IV Lung Cancer AJCC v8

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL

No Results Yet

NCT07007065 | RECRUITING | PHASE3

561 participants

Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2025-11-05

Completion:

2033-03-31

Conditions

• Neovascular Age-related Macular Degeneration

Interventions

• DRUG

No Results Yet

NCT07005297 | NOT_YET_RECRUITING

1000 participants

Clinical Genetics Branch Eligibility Screening Survey

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-04

Start Date:

2026-09-09

Completion:

2035-01-01

Conditions

• Melanoma
• Li-Fraumeni Syndrome
• Pulmonary Blastoma
• Chordoma
• Congenital Bone Marrow Failure Syndromes
• Costello Syndrome
• Fanconi Anemia
• CFC Syndrome (CFCS)
• Legius Syndrome
• RASopathies

No Results Yet

NCT06997809 | RECRUITING | NA

187 participants

ENDometriosis: Evaluation of Detection and Need for ALGOlogic Care Before Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2026-08-05

Completion:

2030-12-31

Conditions

• Endometriosis, Pain

Interventions

• OTHER

No Results Yet

NCT06997588 | RECRUITING | PHASE2

104 participants

EPIK-P4: A Phase II Single-arm Study to Assess the Efficacy, Safety and Pharmacokinetics of Alpelisib (BYL719) in Pediatric and Adult Patients With PIK3CA-related Overgrowth Spectrum (PROS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2025-10-09

Completion:

2028-08-02

Conditions

• PIK3CA-related Overgrowth Spectrum (PROS)

Interventions

• DRUG

No Results Yet

NCT06995885 | ENROLLING_BY_INVITATION

30 participants

Development of an Interview-Informed Timeline Follow-Back (TLFB) for Opioid Use in the Era of Fentanyl

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-04

Start Date:

2026-09-09

Completion:

2027-05-31

Conditions

• Substance Use Disorders (SUDs)

No Results Yet

NCT06991751 | NOT_YET_RECRUITING

50 participants

A Natural History of Cardiometabolic Disease Among US Bhutanese: Developing the Cross-Sectional Bhutanese Community of Central Ohio Health Study to Understand Acculturation as Synergizing Socioenvironmental and Biobehavioral Risk Factors Propagating ...

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-04

Start Date:

2026-09-09

Completion:

2027-08-31

Conditions

• Cardiometabolic Risk Factors
• Mental Health

No Results Yet

NCT06991738 | NOT_YET_RECRUITING | PHASE1/PHASE2

18 participants

177Lu-DOTA-EB-TATE in Adult Patients With Metastatic, Radioactive Iodine Non-Responsive Oncocytic (Hurthle-Cell) Thyroid Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2026-09-09

Completion:

2032-07-01

Conditions

• Thyroid Cancer

Interventions

• DIAGNOSTIC_TEST
• OTHER
• DRUG

No Results Yet

NCT06989957 | RECRUITING | PHASE1

40 participants

Psilocybin and Methylenedioxymethamphetamine (MDMA) for Post-traumatic Stress Disorder (PTSD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2025-09-17

Completion:

2028-08-31

Conditions

• Posttraumatic Stress Disorder

Interventions

• DRUG

No Results Yet

NCT06980519 | TEMPORARILY_NOT_AVAILABLE

MNPR-101-PCTA-177Lu Expanded Access Program (EAP) for Patients With Solid Tumor Cancer

Study Type:

EXPANDED_ACCESS

Last Updated:

2026-09-04

Conditions

• Cancer
• Solid Tumor
• Solid Tumor Cancer
• Oncology
• uPAR-positive Solid Tumor
• Urokinase Plasminogen Activator Receptor-positive Solid Tumor

Interventions

• BIOLOGICAL

No Results Yet

NCT06980506 | TEMPORARILY_NOT_AVAILABLE

MNPR-101-DFO*-89Zr Expanded Access Program (EAP) for Patients With Solid Tumor Cancer

Study Type:

EXPANDED_ACCESS

Last Updated:

2026-09-04

Conditions

• Cancer
• Solid Tumor
• Solid Tumor, Adult

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT06973811 | RECRUITING | PHASE2

47 participants

ZR-MTX for PIOL Phase II Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2024-10-10

Completion:

2027-10-30

Conditions

• Primary Intraocular Lymphoma

Interventions

• DRUG

No Results Yet

NCT06968988 | SUSPENDED | PHASE1

18 participants

Zanzalintinib in Combination With Ipilimumab and Nivolumab in Patients With Metastatic Soft Tissue Sarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2026-01-05

Completion:

2029-02-12

Conditions

• Metastatic Soft-tissue Sarcoma

Interventions

• DRUG

No Results Yet

NCT06968845 | RECRUITING | PHASE2

120 participants

A Phase 2 Study of LTI-03 in Patients With Idiopathic Pulmonary Fibrosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2026-02-02

Completion:

2027-09-30

Conditions

• Idiopathic Pulmonary Fibrosis (IPF)

Interventions

• DRUG
• DEVICE

No Results Yet

NCT06965725 | RECRUITING

22 participants

Paired-Ring Mitral Annuloplasty Ring Sizing Device

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-04

Start Date:

2025-07-03

Completion:

2026-11-30

Conditions

• Heart Valve Diseases

Interventions

• DEVICE

No Results Yet

NCT06959511 | RECRUITING | PHASE2

45 participants

Zanzalintinib for the Treatment of Advanced Thyroid Cancer Before Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2025-07-22

Completion:

2028-03-01

Conditions

• Neoadjuvant Treatment
• Thyroid Cancer

Interventions

• DRUG

No Results Yet

NCT06957418 | RECRUITING | PHASE2

900 participants

Alzheimer's Tau Platform: Master Protocol

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2026-07-06

Completion:

2028-08-31

Conditions

• Preclinical Alzheimer's Disease
• Alzheimer Disease
• Prodromal Alzheimer's Disease

Interventions

• DRUG

No Results Yet

NCT06952660 | RECRUITING | PHASE4

100 participants

Ocular Assessments in Patients Treated With Tivdak® in Recurrent or Metastatic Cervical Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2025-05-07

Completion:

2028-12-13

Conditions

• Cervical Cancer

Interventions

• DRUG

No Results Yet

NCT06951711 | RECRUITING | PHASE3

274 participants

A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-2)

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2025-06-13

Completion:

2026-11-02

Conditions

• Bipolar Disorder Type I With Mania or Mania With Mixed Features

Interventions

• DRUG
• OTHER

No Results Yet

NCT06951698 | RECRUITING | PHASE3

274 participants

A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2025-06-11

Completion:

2026-11-01

Conditions

• Bipolar-I Disorder With Mania or Mania With Mixed Features

Interventions

• DRUG
• OTHER

No Results Yet

NCT06948214 | RECRUITING | PHASE3

150 participants

Phase 3 Study of LUM-201 in Children With Growth Hormone Deficiency

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2026-05-20

Completion:

2027-12-31

Conditions

• Growth Hormone Deficiency (GHD)

Interventions

• DRUG
• OTHER

No Results Yet

NCT06948110 | RECRUITING

300 participants

Deciphering the Genetic Architecture of Autoimmune Diseases

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-04

Start Date:

2026-09-09

Completion:

2030-04-22

Conditions

• Autoimmune Diseases

No Results Yet

NCT06948097 | RECRUITING | PHASE1

30 participants

Syk Inhibition in MItigating Lung Allograft Rejection (SIMILAR): A Trial to Evaluate the Safety and Tolerability of Fostamatinib in Lung Transplant Patients With Donor-Specific Antibodies

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2026-09-09

Completion:

2028-07-14

Conditions

• Lung Transplantation

Interventions

• DRUG

No Results Yet

NCT06942455 | RECRUITING | NA

300 participants

A Sleep Hygiene Intervention to Improve Sleep Health in Urban, Latino Middle School Children

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2025-06-25

Completion:

2029-03-31

Conditions

• Sleep
• Sleep Quality
• Intervention Study
• Ethnic Minority

Interventions

• BEHAVIORAL

No Results Yet

NCT06940752 | ENROLLING_BY_INVITATION | NA

30 participants

VINTAGE (Ventricular Intramyocardial Navigation for Tachycardia Ablation Guided by Electrograms) Using Commercial Off-The-Shelf (COTS) Catheters

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2026-09-09

Completion:

2026-12-01

Conditions

• Ventricular Arrhythmia

Interventions

• DEVICE

No Results Yet