Clinical Trials Updated in 2026

NCT06400472 | RECRUITING | PHASE1

575 participants

A Study of Sofe-M in Participants With Selected Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2024-05-20
Completion:: 2029-06-30

Conditions

Ovarian Neoplasms
Endometrial Neoplasms
Uterine Cervical Neoplasms
Carcinoma, Non-Small-Cell Lung
Triple Negative Breast Neoplasms
Pancreatic Neoplasm
Colorectal Neoplasms

Interventions

DRUG

No Results Yet

NCT06399432 | RECRUITING | NA

36 participants

Mediterranean Diet vs no Dietary Intervention for Improving Signs and Symptoms of Psoriasis in Patients Treated With Anti-IL-17 or Anti-IL-23 Inhibitors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2022-10-18
Completion:: 2027-01-01

Conditions

Psoriasis

Interventions

BEHAVIORAL

No Results Yet

NCT06398418 | RECRUITING | PHASE1

33 participants

R-5780-01 In Combination With PD-1 Checkpoint Inhibitors (Checkpoint Protein on Immune Cells Called T Cells) in Patients With Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2025-08-01
Completion:: 2027-04-30

Conditions

Solid Tumor, Adult
Solid Tumor
Melanoma
Basal Cell Cancer
Squamous Cell Cancer
Adenoma

Interventions

DRUG

No Results Yet

NCT06393738 | RECRUITING | PHASE1

329 participants

A Study of ARV-393 in Relapsed/Refractory Non-Hodgkin Lymphoma.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2024-09-05
Completion:: 2028-03-31

Conditions

Relapsed/Refractory (R/R) Mature B Cell Non Hodgkin Lymphoma (NHL)
Relapsed/Refractory (R/R) Angioimmunoblastic T-cell Lymphoma (AITL)

Interventions

DRUG

No Results Yet

NCT06390059 | COMPLETED | PHASE2

84 participants

EF-39 PANOVA-4: Study of Tumor Treating Fields Concomitant With Atezolizumab, Gemcitabine and Nab-Paclitaxel as First-LineTreatment for Metastatic Pancreatic Ductal Adenocarcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2023-08-21
Completion:: 2025-11-18

Conditions

Metastatic Pancreatic Ductal Adenocarcinoma

Interventions

DEVICE
DRUG

No Results Yet

NCT06384898 | RECRUITING | NA

480 participants

Remote Tai Chi for Knee Osteoarthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2025-04-07
Completion:: 2027-03-05

Conditions

Knee Osteoarthritis

Interventions

OTHER

No Results Yet

NCT06384222 | ACTIVE_NOT_RECRUITING | PHASE2

32 participants

Hyperpolarized (HP) 13C Pyruvate Magnetic Resonance Imaging (MRI) for Response Monitoring to Neoadjuvant Abiraterone

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2024-12-09
Completion:: 2026-08-31

Conditions

High Risk Prostate Carcinoma
Prostate Cancer

Interventions

DRUG
PROCEDURE

No Results Yet

NCT06377852 | RECRUITING | PHASE3

500 participants

The CDK4/6 Inhibitor Dosing Knowledge (CDK) Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2024-10-29
Completion:: 2028-08-31

Conditions

Metastatic Breast Cancer

Interventions

DRUG

No Results Yet

NCT06375460 | NOT_YET_RECRUITING | NA

100 participants

Real-time Engagement for Learning to Effectively Control Type 2 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2026-09-30
Completion:: 2029-07-31

Conditions

Diabetes Mellitus, Type 2
Lifestyle
Hyperglycemia
Physical Inactivity

Interventions

BEHAVIORAL

No Results Yet

NCT06369259 | RECRUITING | PHASE2

33 participants

Open-label Phase 2 Study of Avutometinib (RAF/MEK Clamp) in Combination With Defactinib (FAK Inhibitor) and Cetuximab in Patients With Unresectable, Anti-EGFR-Refractory Advanced Colorectal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2025-02-24
Completion:: 2029-02-01

Conditions

Advanced Colorectal Cancer

Interventions

DRUG

No Results Yet

NCT06368648 | RECRUITING

581 participants

CoMind Early Feasibility Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-04
Start Date:: 2024-11-27
Completion:: 2026-11-30

Conditions

Intracranial Pressure
Intracranial Pressure Changes
Traumatic Brain Injury
Intracerebral Hemorrhage
Encephalitis
Encephalopathy
Hydrocephalus
Stroke
Autoregulation

No Results Yet

NCT06364410 | RECRUITING | PHASE1

48 participants

Testing the Combination of the Anticancer Drugs Trastuzumab Deruxtecan (DS-8201a) and Azenosertib (ZN-c3) in Patients With Stomach or Other Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2025-02-03
Completion:: 2027-07-08

Conditions

Clinical Stage III Gastric Cancer AJCC v8
Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
Clinical Stage IV Gastric Cancer AJCC v8
Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8
Locally Advanced Gastric Carcinoma
Locally Advanced Gastroesophageal Junction Adenocarcinoma
Locally Advanced Malignant Solid Neoplasm
Metastatic Gastric Carcinoma
Metastatic Gastroesophageal Junction Adenocarcinoma
Metastatic Malignant Solid Neoplasm
Unresectable Gastric Carcinoma
Unresectable Gastroesophageal Junction Adenocarcinoma
Unresectable Malignant Solid Neoplasm

Interventions

DRUG
PROCEDURE
BIOLOGICAL

No Results Yet

NCT06355414 | RECRUITING | PHASE1

40 participants

Psilocybin in Chronic Low Back Pain and Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2024-04-22
Completion:: 2026-12-30

Conditions

Chronic Low-back Pain
Depression

Interventions

DRUG

No Results Yet

NCT06353711 | RECRUITING | NA

180 participants

Caring Connections Youth Suicide Detection and Intervention Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2025-08-14
Completion:: 2027-05-31

Conditions

Suicide
Suicide Prevention
Suicide Ideation
Suicide Attempt

Interventions

BEHAVIORAL

No Results Yet

NCT06348082 | ACTIVE_NOT_RECRUITING | NA

29 participants

Project Women's Insomnia Sleep Health Equity Study (WISHES)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2026-01-06
Completion:: 2026-09-30

Conditions

Insomnia
Sleep Health
Cardiometabolic Health

Interventions

BEHAVIORAL

No Results Yet

NCT06333392 | RECRUITING | NA

1070 participants

Total Underwater Colonoscopy (TUC) for Improved Colorectal Cancer Screening: A Randomized Controlled Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2024-10-23
Completion:: 2026-12-31

Conditions

Colorectal Neoplasia
Screening Colonoscopy
Colorectal Cancer
Colorectal Cancer Screening
Vasovagal Reaction

Interventions

PROCEDURE

No Results Yet

NCT06327750 | RECRUITING | NA

23 participants

The Microcirculation, Dialysis Modality and Sequestered Salt

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2026-06-02
Completion:: 2028-05-31

Conditions

End-stage Renal Disease

Interventions

DEVICE

No Results Yet

NCT06323057 | COMPLETED | NA

36 participants

Modulating Reward Learning Using Transcranial Magnetic Stimulation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2024-02-14
Completion:: 2026-04-30

Conditions

Behavior

Interventions

DEVICE

No Results Yet

NCT06321302 | ACTIVE_NOT_RECRUITING | PHASE2

190 participants

A Study to Test Whether BI 764524 Helps People With an Eye Condition Called Diabetic Retinopathy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2024-05-15
Completion:: 2027-03-05

Conditions

Diabetic Retinopathy

Interventions

DRUG

No Results Yet

NCT06311214 | RECRUITING | PHASE2

500 participants

Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2025-03-18
Completion:: 2028-03-31

Conditions

Advanced Malignant Solid Neoplasm
Metastatic Malignant Solid Neoplasm

Interventions

PROCEDURE
OTHER
DRUG
BIOLOGICAL

No Results Yet

NCT06303193 | RECRUITING | PHASE1/PHASE2

160 participants

Pacritinib, a Kinase Inhibitor of CSF1R, IRAK1, JAK2, and FLT3, in Adults and Pediatric Participants 12 Years of Age or Older With Myelodysplastic Syndromes or Myelodysplastic/Myeloproliferative Neoplasms

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2026-09-09
Completion:: 2030-01-01

Conditions

Myelodysplastic Syndromes

Interventions

DRUG

No Results Yet

NCT06298084 | RECRUITING | PHASE1/PHASE2

152 participants

Dose-Expansion Modular Study To Explore the Safety, Tolerability, and Anti-tumor Activity of HER3- DXd Monotherapy and Combinations in Patients With Inoperable Advanced Breast Cancer (ABC) After Progression on T-DXd

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2024-03-21
Completion:: 2027-09-30

Conditions

Breast Cancer Metastatic
HER2-positive Metastatic Breast Cancer
HER2 Low Breast Carcinoma
Advanced Breast Cancer

Interventions

DRUG

No Results Yet

NCT06295679 | ACTIVE_NOT_RECRUITING

7000 participants

A Study Assessing Repatha® in Combination With Standard of Care (SOC) Compared With SOC on Major Cardiovascular Events in Chinese Participants With Atherosclerotic Cardiovascular Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-04
Start Date:: 2022-12-19
Completion:: 2028-12-19

Conditions

Major Cardiovascular Event
Established Atherosclerotic Cardiovascular Disease

No Results Yet

NCT06295367 | ACTIVE_NOT_RECRUITING | NA

760 participants

Cost Communication and Financial Navigation in Cancer Patients (COSTCOM)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2024-04-10
Completion:: 2027-11-01

Conditions

Malignant Solid Neoplasm

Interventions

OTHER

No Results Yet

NCT06283355 | ACTIVE_NOT_RECRUITING | PHASE1

78 participants

Comparing Single Versus Repeat NMT on the Diversity of the Neonatal Nasal Microbiome

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2024-09-03
Completion:: 2026-04-16

Conditions

Staphylococcus Aureus
Microbial Colonization
Neonatal Infection

Interventions

BIOLOGICAL

No Results Yet

NCT06280820 | ENROLLING_BY_INVITATION

2000 participants

Multi-Scale Analysis of Phenotypes in Heart Failure (MAP-HEART)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-04
Start Date:: 2026-09-09
Completion:: 2028-04-30

Conditions

Heart Failure

No Results Yet

NCT06280560 | RECRUITING

60 participants

Impact of IVF Hormonal Therapy on Endometrial Receptivity and Endometrial Senescent Cell Pathological Accumulation

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-04
Start Date:: 2024-02-01
Completion:: 2026-12-30

Conditions

Endometrial Receptivity

Interventions

PROCEDURE

No Results Yet

NCT06274749 | RECRUITING | NA

180 participants

Effects of Urolithin A Supplementation on Glucose Metabolism in Healthy Adults 55 >= Years Old: A Randomized Triple-Masked Controlled Clinical Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2026-09-09
Completion:: 2027-03-31

Conditions

Healthy Volunteer

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06274515 | RECRUITING | PHASE4

320 participants

A Study to Investigate Mechanisms of Resistance to Breast Cancer Therapies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2024-04-02
Completion:: 2027-12-31

Conditions

Breast Cancer

Interventions

PROCEDURE

No Results Yet

NCT06262789 | RECRUITING | NA

264 participants

RAT-HEMATO : Return to Work After Malignant Hemopathy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2024-09-27
Completion:: 2028-03-31

Conditions

Leukemia
Lymphoma
Multiple Myeloma

Interventions

OTHER

No Results Yet

NCT06254794 | RECRUITING | NA

19 participants

Effect of BFR Rehab After Achilles Tendon Rupture

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2018-11-13
Completion:: 2026-12-31

Conditions

Achilles Tendon Rupture

Interventions

DEVICE
OTHER

No Results Yet

NCT06250712 | RECRUITING | NA

588 participants

Hativ® ELectrocardiogram Monitoring on Patients With Suspected Arrhythmia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2024-02-22
Completion:: 2026-12-31

Conditions

Arrhythmia

Interventions

DEVICE

No Results Yet

NCT06247995 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

20 participants

A Phase I/II, Dose Finding and Optimization Study of [177Lu]Lu-NeoB in Combination With Capecitabine in Patients With GRPR+, ER+, HER2- Metastatic Breast Cancer After Progression on Previous Endocrine Therapy in Combination With a CDK4/6 Inhibitor.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2024-08-14
Completion:: 2027-04-14

Conditions

Breast Cancer

Interventions

DRUG

No Results Yet

NCT06236438 | RECRUITING | PHASE2/PHASE3

840 participants

Study to Evaluate Adverse Events, Optimal Dose, and Change in Disease Activity, With Livmoniplimab in Combination With Budigalimab Plus Chemotherapy Versus IV Infused Pembrolizumab Plus Chemotherapy in Adult Participants With Untreated Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2024-04-10
Completion:: 2031-10-31

Conditions

Non-Small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT06226883 | RECRUITING | PHASE2

385 participants

A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2024-07-18
Completion:: 2028-09-30

Conditions

Inflammatory Bowel Diseases
Crohn's Disease

Interventions

DRUG

No Results Yet

NCT06226181 | COMPLETED | NA

22 participants

Amniotic Membrane for Dacryocystorhinostomy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2024-01-01
Completion:: 2025-02-01

Conditions

Nasolacrimal Duct Obstruction
Dacryocystorhinostomy

Interventions

PROCEDURE

No Results Yet

NCT06221969 | COMPLETED | PHASE3

1024 participants

A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 Inhibitor

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2024-01-16
Completion:: 2026-03-04

Conditions

Type 2 Diabetes

Interventions

DRUG

No Results Yet

NCT06216665 | COMPLETED | NA

4 participants

Effect of Pulsatile Hormone Administration on Insulin Action

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2024-03-04
Completion:: 2024-05-09

Conditions

Insulin Sensitivity

Interventions

OTHER

No Results Yet

NCT06208189 | ACTIVE_NOT_RECRUITING | NA

15 participants

Is the Degree of Perceived Effort During Resistance Exercise Important for Improvements in Blood Glucose

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2024-06-12
Completion:: 2026-10-30

Conditions

PreDiabetes
Type 2 Diabetes Mellitus

Interventions

BEHAVIORAL

No Results Yet

NCT06203600 | RECRUITING | PHASE2/PHASE3

224 participants

Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2024-06-24
Completion:: 2027-10-31

Conditions

Advanced Esophageal Adenocarcinoma
Advanced Gastric Adenocarcinoma
Advanced Gastroesophageal Junction Adenocarcinoma
Clinical Stage II Esophageal Adenocarcinoma AJCC v8
Clinical Stage III Esophageal Adenocarcinoma AJCC v8
Clinical Stage III Gastric Cancer AJCC v8
Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
Clinical Stage IV Esophageal Adenocarcinoma AJCC v8
Clinical Stage IV Gastric Cancer AJCC v8
Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8
Metastatic Esophageal Adenocarcinoma
Metastatic Gastric Adenocarcinoma
Metastatic Gastroesophageal Junction Adenocarcinoma
Unresectable Esophageal Adenocarcinoma
Unresectable Gastric Adenocarcinoma
Unresectable Gastroesophageal Junction Adenocarcinoma

Interventions

PROCEDURE
BIOLOGICAL
DRUG
OTHER

No Results Yet