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Comparing Single Versus Repeat NMT on the Diversity of the Neonatal Nasal Microbiome

NCT06283355 · Status: RECRUITING · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 175

Last updated 2025-09-11

No results posted yet for this study

Summary

This study aims to determine whether a parent-to-child nasal microbiota transplant (NMT) can seed and engraft parental organisms into the neonatal microbiome and increase the neonatal microbiome diversity.

Conditions

  • Staphylococcus Aureus
  • Microbial Colonization
  • Neonatal Infection

Interventions

BIOLOGICAL

Nasal Microbiota Transplant (NMT)

nasal microbiota transplant

BIOLOGICAL

Placebo

Placebo sterile swab

Sponsors & Collaborators

Principal Investigators

  • Aaron Milstone, MD · Johns Hopkins University

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
0 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-09-03
Primary Completion
2026-06-01
Completion
2026-12-31
FDA Drug
Yes

Countries

  • United States

Study Locations

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Entities

Drugs
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06283355 on ClinicalTrials.gov