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Clinical Trials

Showing trials with last updates posted in 2026.

NCT04391049 | ACTIVE_NOT_RECRUITING | PHASE1
16 participants

Testing the Addition of the Anti-cancer Viral Therapy Telomelysin™ to Chemoradiation for Patients With Advanced Esophageal Cancer and Are Not Candidates for Surgery

Study Type:
INTERVENTIONAL
Last Updated:
2026-09-04
Start Date:
2021-12-02
Completion:
2024-10-06
Conditions
  • Advanced Esophageal Adenocarcinoma
  • Advanced Gastroesophageal Junction Adenocarcinoma
  • Clinical Stage II Esophageal Adenocarcinoma AJCC v8
  • Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8
  • Clinical Stage IIA Esophageal Adenocarcinoma AJCC v8
  • Clinical Stage IIA Gastroesophageal Junction Adenocarcinoma AJCC v8
  • Clinical Stage IIB Esophageal Adenocarcinoma AJCC v8
  • Clinical Stage IIB Gastroesophageal Junction Adenocarcinoma AJCC v8
  • Clinical Stage III Esophageal Adenocarcinoma AJCC v8
  • Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
  • Pathologic Stage II Esophageal Adenocarcinoma AJCC v8
  • Pathologic Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8
  • Pathologic Stage IIA Esophageal Adenocarcinoma AJCC v8
  • Pathologic Stage IIA Gastroesophageal Junction Adenocarcinoma AJCC v8
  • Pathologic Stage IIB Esophageal Adenocarcinoma AJCC v8
  • Pathologic Stage IIB Gastroesophageal Junction Adenocarcinoma AJCC v8
  • Pathologic Stage III Esophageal Adenocarcinoma AJCC v8
  • Pathologic Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
  • Pathologic Stage IIIA Esophageal Adenocarcinoma AJCC v8
  • Pathologic Stage IIIA Gastroesophageal Junction Adenocarcinoma AJCC v8
  • Pathologic Stage IIIB Esophageal Adenocarcinoma AJCC v8
  • Pathologic Stage IIIB Gastroesophageal Junction Adenocarcinoma AJCC v8
  • Postneoadjuvant Therapy Stage II Esophageal Adenocarcinoma AJCC v8
  • Postneoadjuvant Therapy Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8
  • Postneoadjuvant Therapy Stage III Esophageal Adenocarcinoma AJCC v8
  • Postneoadjuvant Therapy Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
  • Postneoadjuvant Therapy Stage IIIA Esophageal Adenocarcinoma AJCC v8
  • Postneoadjuvant Therapy Stage IIIA Gastroesophageal Junction Adenocarcinoma AJCC v8
  • Postneoadjuvant Therapy Stage IIIB Esophageal Adenocarcinoma AJCC v8
  • Postneoadjuvant Therapy Stage IIIB Gastroesophageal Junction Adenocarcinoma AJCC v8
  • Unresectable Gastroesophageal Junction Adenocarcinoma
  • Squamous Cell Carcinoma
  • Squamous Cell Cancer
Interventions
  • DRUG
  • RADIATION
  • BIOLOGICAL
Results Available
NCT04367246 | RECRUITING
300 participants

Li-Fraumeni Syndrome/TP53 Biobank

Study Type:
OBSERVATIONAL
Last Updated:
2026-09-04
Start Date:
2019-09-24
Completion:
2029-09-24
Conditions
  • Li-Fraumeni Syndrome
  • Li-Fraumeni-Like Syndrome
Interventions
  • OTHER
No Results Yet
NCT04267848 | RECRUITING | PHASE3
1210 participants

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

Study Type:
INTERVENTIONAL
Last Updated:
2026-09-04
Start Date:
2020-06-16
Completion:
2027-01-31
Conditions
  • Lung Non-Small Cell Carcinoma
  • Lung Non-Small Cell Squamous Carcinoma
  • Lung Non-Squamous Non-Small Cell Carcinoma
  • Stage II Lung Cancer AJCC v8
  • Stage IIIA Lung Cancer AJCC v8
  • Stage IIIB Lung Cancer AJCC v8
Interventions
  • PROCEDURE
  • DRUG
  • OTHER
  • BIOLOGICAL
No Results Yet
NCT04176172 | ACTIVE_NOT_RECRUITING | PHASE3
340 participants

Optimizing Tobacco Use Treatment for PLWHA

Study Type:
INTERVENTIONAL
Last Updated:
2026-09-04
Start Date:
2020-02-17
Completion:
2026-11-30
Conditions
  • HIV/AIDS
  • Nicotine Dependence
Interventions
  • DRUG
  • BEHAVIORAL
No Results Yet
NCT04005690 | RECRUITING | EARLY_PHASE1
90 participants

Targeted Pathway Inhibition in Patients With Pancreatic Cancer

Study Type:
INTERVENTIONAL
Last Updated:
2026-09-04
Start Date:
2019-08-01
Completion:
2027-06-01
Conditions
  • Locally Advanced Pancreatic Ductal Adenocarcinoma
  • Metastatic Pancreatic Ductal Adenocarcinoma
  • Stage II Pancreatic Cancer AJCC v8
  • Stage III Pancreatic Cancer AJCC v8
  • Stage IV Pancreatic Cancer AJCC v8
  • Unresectable Pancreatic Ductal Adenocarcinoma
  • Borderline Resectable Pancreatic Ductal Adenocarcinoma
  • Resectable Pancreatic Ductal Adenocarcinoma
Interventions
  • DRUG
  • BIOLOGICAL
No Results Yet
NCT03942081 | RECRUITING | NA
500 participants

Diabetic Foot Ulcer Imaging- Study 2

Study Type:
INTERVENTIONAL
Last Updated:
2026-09-04
Start Date:
2017-09-05
Completion:
2026-12-31
Conditions
  • Foot Ulcer
  • Foot Ulcer, Diabetic
Interventions
  • DEVICE
No Results Yet
NCT03911388 | RECRUITING | PHASE1
24 participants

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

Study Type:
INTERVENTIONAL
Last Updated:
2026-09-04
Start Date:
2019-09-12
Completion:
2026-09-01
Conditions
  • Neoplasms, Brain
  • Glioblastoma Multiforme
  • Glioblastoma of Cerebellum
  • Neoplasms
  • Astrocytoma
  • Astrocytoma, Cerebellar
  • Neuroectodermal Tumors
  • Neuroectodermal Tumors, Primitive
  • Cerebellar PNET, Childhood
  • Cerebellar Neoplasms
  • Cerebellar Neoplasms, Primary
  • Cerebellar Neoplasm, Malignant
  • Cerebellar Neoplasm Malignant Primary
  • Neoplasm Metastases
  • Neoplasm Malignant
  • Neoplasms, Neuroepithelial
  • Neoplasms, Germ Cell and Embryonal
  • Neoplasms by Histologic Type
  • Neoplasms, Glandular and Epithelial
  • Neoplasms, Nerve Tissue
  • Central Nervous System Neoplasms, Primary
  • Central Nervous System Neoplasms, Malignant
  • Nervous System Neoplasms
  • Neoplasms by Site
  • Brain Diseases
  • Central Nervous System Diseases
  • Nervous System Diseases
  • Medulloblastoma Recurrent
  • HSV
  • Virus
  • Pediatric Brain Tumor
  • Nervous System Cancer
  • Primitive Neuroectodermal Tumor (PNET) of Cerebellum
Interventions
  • BIOLOGICAL
No Results Yet
NCT03866382 | RECRUITING | PHASE2
314 participants

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

Study Type:
INTERVENTIONAL
Last Updated:
2026-09-04
Start Date:
2019-05-13
Completion:
2027-02-28
Conditions
  • Bladder Adenocarcinoma
  • Bladder Clear Cell Adenocarcinoma
  • Bladder Mixed Adenocarcinoma
  • Bladder Neuroendocrine Carcinoma
  • Bladder Small Cell Neuroendocrine Carcinoma
  • Bladder Squamous Cell Carcinoma
  • Chromophobe Renal Cell Carcinoma
  • Collecting Duct Carcinoma
  • Invasive Bladder Giant Cell Urothelial Carcinoma
  • Invasive Bladder Lymphoepithelioma-Like Carcinoma
  • Invasive Bladder Nested Urothelial Carcinoma
  • Invasive Bladder Plasmacytoid Urothelial Carcinoma
  • Invasive Bladder Sarcomatoid Urothelial Carcinoma
  • Invasive Bladder Urothelial Carcinoma
  • Kidney Medullary Carcinoma
  • Large Cell Neuroendocrine Carcinoma
  • Malignant Testicular Leydig Cell Tumor
  • Malignant Testicular Sertoli Cell Tumor
  • Metastatic Bladder Carcinoma
  • Metastatic Bladder Clear Cell (Glycogen-Rich) Urothelial Carcinoma
  • Metastatic Bladder Giant Cell Urothelial Carcinoma
  • Metastatic Bladder Large Cell Neuroendocrine Carcinoma
  • Metastatic Bladder Lipid-Rich Urothelial Carcinoma
  • Metastatic Bladder Micropapillary Urothelial Carcinoma
  • Metastatic Bladder Plasmacytoid Urothelial Carcinoma
  • Metastatic Bladder Sarcomatoid Urothelial Carcinoma
  • Metastatic Bladder Small Cell Neuroendocrine Carcinoma
  • Metastatic Bladder Squamous Cell Carcinoma
  • Metastatic Chromophobe Renal Cell Carcinoma
  • Metastatic Kidney Medullary Carcinoma
  • Metastatic Malignant Genitourinary System Neoplasm
  • Metastatic Papillary Renal Cell Carcinoma
  • Metastatic Penile Carcinoma
  • Metastatic Prostate Small Cell Neuroendocrine Carcinoma
  • Metastatic Sarcomatoid Renal Cell Carcinoma
  • Metastatic Urethral Carcinoma
  • Papillary Renal Cell Carcinoma
  • Sarcomatoid Renal Cell Carcinoma
  • Stage IV Bladder Cancer AJCC v8
  • Stage IV Penile Cancer AJCC v8
  • Stage IV Renal Cell Cancer AJCC v8
  • Stage IV Urethral Cancer AJCC v8
  • Stage IVB Prostate Cancer AJCC v8
  • Urachal Adenocarcinoma
  • Urethral Clear Cell Adenocarcinoma
Interventions
  • PROCEDURE
  • DRUG
  • BIOLOGICAL
No Results Yet
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