Clinical Trials Updated in 2026

NCT05989802 | RECRUITING | NA

2100 participants

Rapid Research in Diagnostics Development for TB Network (R2D2 Kids) and Assessing Diagnostics At POC for TB in Children (ADAPT for Kids)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2024-01-26
Completion:: 2026-09-01

Conditions

Tuberculosis
Diagnostics
Global Health

Interventions

DIAGNOSTIC_TEST
OTHER

No Results Yet

NCT05981807 | COMPLETED

200 participants

HPV Infection, Sexually Transmitted Infections and Anal Dysplasia in the Transgender Population

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-02
Start Date:: 2024-10-15
Completion:: 2025-06-13

Conditions

Human Papillomavirus Infection
Human Immunodeficiency Virus Infection
Sexually Transmitted Diseases

No Results Yet

NCT05978167 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

20 participants

Targeting Drug Memories With Methylphenidate

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-06-23
Completion:: 2031-03-31

Conditions

Substance Use Disorder
Cocaine Use Disorder

Interventions

DRUG
BEHAVIORAL

No Results Yet

NCT05976763 | RECRUITING | PHASE3

421 participants

Testing Continuous Versus Intermittent Treatment With the Study Drug Zanubrutinib for Older Patients With Previously Untreated Mantle Cell Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-10-20
Completion:: 2038-08-31

Conditions

Mantle Cell Lymphoma

Interventions

DRUG
BIOLOGICAL
OTHER
PROCEDURE

No Results Yet

NCT05968846 | COMPLETED | PHASE2

19 participants

Repeat PET/CT Imaging of Patients With Amyloid 124I-AT-01 to Measure Changes in Organ-specific Amyloid Load

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2022-12-07
Completion:: 2023-08-01

Conditions

Systemic Amyloidosis

Interventions

DRUG

Results Available

NCT05968326 | RECRUITING | PHASE2

260 participants

A Study of the Efficacy and Safety of Adjuvant Autogene Cevumeran Plus Atezolizumab and mFOLFIRINOX Versus mFOLFIRINOX Alone in Participants With Resected PDAC

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-10-18
Completion:: 2031-01-01

Conditions

Adenocarcinoma, Pancreatic Ductal

Interventions

DRUG

No Results Yet

NCT05967468 | ACTIVE_NOT_RECRUITING | NA

100 participants

Evaluation of Family-Based Behavioral Treatments for Youth With Anxiety and Obsessive-Compulsive Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-09-14
Completion:: 2025-12-30

Conditions

Obsessive-Compulsive Disorder in Children
Anxiety Disorder of Childhood
Social Anxiety Disorder of Childhood
Obsessive-Compulsive Disorder in Adolescence
Generalized Anxiety Disorder
Separation Anxiety
Panic Disorder
Panic Disorder With Agoraphobia
Panic Attacks

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT05964504 | RECRUITING

150 participants

Improving Survival for Metastatic Lobular Breast Cancer (PLUMB Registry)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-12-20
Completion:: 2036-02-28

Conditions

Metastatic Breast Cancer
Lobular Breast Carcinoma

Interventions

PROCEDURE

No Results Yet

NCT05952648 | ACTIVE_NOT_RECRUITING | NA

126 participants

HAP/VAP Diagnosis in Critically Ill Septic Patients Using a Multiplex PCR Array

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2024-04-03
Completion:: 2026-08-20

Conditions

HAP - Hospital Acquired Pneumonia
VAP - Ventilator Associated Pneumonia

Interventions

PROCEDURE
DIAGNOSTIC_TEST

No Results Yet

NCT05951959 | ACTIVE_NOT_RECRUITING | PHASE2

108 participants

A Study of Acalabrutinib Plus Venetoclax and Rituximab in Participants With Treatment Naïve Mantle Cell Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-12-13
Completion:: 2028-10-31

Conditions

Mantle Cell Lymphoma (MCL)

Interventions

DRUG

No Results Yet

NCT05945199 | RECRUITING | NA

40 participants

Effectiveness of tDCS on Reducing Craving in Patients Practicing Chemsex: a Single-center, Double-blind, Randomized Controlled Pilot Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2024-07-29
Completion:: 2028-10-31

Conditions

Chemsex

Interventions

DEVICE
BEHAVIORAL
OTHER

No Results Yet

NCT05942794 | COMPLETED | NA

200 participants

Identification of Oral Lesions Through an Autofluorescence System

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-06-01
Completion:: 2024-03-01

Conditions

Oral Leukoplakia
Autofluorescence
Secondary Prevention
Keratosis
Oral Lichen Planus
Oral Cancer
Oral Disease

Interventions

DEVICE

No Results Yet

NCT05941052 | RECRUITING | NA

1350 participants

Assessing Diagnostics At Point-of-care for Tuberculosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-08-28
Completion:: 2028-09-30

Conditions

Tuberculosis

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05939180 | RECRUITING | PHASE2/PHASE3

116 participants

VA vs DA for Newly Diagnosed Hig-risk AML

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2024-04-01
Completion:: 2026-06-13

Conditions

Acute Myeloid Leukemia

Interventions

DRUG

No Results Yet

NCT05933083 | ACTIVE_NOT_RECRUITING | NA

516 participants

MCNAIR Study: coMparative effeCtiveness of iN-person and teleheAlth cardIac Rehabilitation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-10-27
Completion:: 2027-12-31

Conditions

Myocardial Infarction
Heart Failure, Systolic
Heart Valve Diseases
Angina, Stable
Coronary Artery Disease
Heart Transplant

Interventions

BEHAVIORAL

No Results Yet

NCT05930496 | TERMINATED | NA

10 participants

Evaluating the Effects of an Exercise Intervention on the Gut Microbiota in Stage II-III Colorectal Cancer Survivors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2025-07-08
Completion:: 2026-06-30

Conditions

Stage II Colorectal Cancer AJCC v8
Stage III Colorectal Cancer AJCC v8
Colorectal Carcinoma

Interventions

PROCEDURE
OTHER
BEHAVIORAL

No Results Yet

NCT05926557 | COMPLETED | NA

20 participants

Treatment of Peri-implant Mucositis by Application of a Spermidine-based Gel

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-07-01
Completion:: 2024-06-01

Conditions

Peri-implant Mucositis
Mucositis Oral

Interventions

PROCEDURE

No Results Yet

NCT05921487 | ACTIVE_NOT_RECRUITING | NA

15 participants

Time Restricted Eating to Mitigate Obesity in Veterans With Spinal Cord Injury

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-09-01
Completion:: 2026-07-01

Conditions

Spinal Cord Injury
Obesity

Interventions

BEHAVIORAL

No Results Yet

NCT05918640 | RECRUITING | PHASE1/PHASE2

63 participants

Lurbinectedin in FET-Fused Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-07-27
Completion:: 2028-07-30

Conditions

Ewing Sarcoma
Desmoplastic Small Round Cell Tumor
Pediatric Cancer
Undifferentiated Sarcoma

Interventions

DRUG

No Results Yet

NCT05911568 | RECRUITING

1060 participants

Treatment With Endovascular Intervention for STroke Patients With Existing Disability

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-11-16
Completion:: 2028-01-15

Conditions

Stroke
Stroke, Acute
Stroke, Ischemic

Interventions

PROCEDURE
OTHER

No Results Yet

NCT05907343 | RECRUITING | NA

180 participants

Closed-Loop Brain Stimulation as a Potential Intervention for Cognitive Decline

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-05-31
Completion:: 2027-10-31

Conditions

Mild Cognitive Impairment
Alzheimer Dementia (AD)

Interventions

DEVICE

No Results Yet

NCT05900882 | COMPLETED | PHASE2

29 participants

SVRd for the Treatment of Newly Diagnosed Multiple Myeloma Patients Presenting With Extramedullary Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2022-07-15
Completion:: 2026-08-30

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT05895162 | COMPLETED | NA

64 participants

Zinc-containing Vaginal Gel and Oral Fluconazole for Vulvovaginal Candidiasis.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-06-10
Completion:: 2026-04-20

Conditions

Vulvovaginal Candidiasis
Vaginal Yeast Infections

Interventions

DRUG

No Results Yet

NCT05889520 | COMPLETED

300 participants

The UFIM (Ultraprocessed Foods In Breast Milk) Project

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-05-23
Completion:: 2026-05-23

Conditions

Child Malnutrition
Child Allergy
Maternal Exposure

No Results Yet

NCT05883748 | ENROLLING_BY_INVITATION | PHASE2/PHASE3

230 participants

HELIOS: Open-Label, Long-Term Extension Study to Investigate the Safety, Tolerability, and Efficacy of DISC-1459 (Bitopertin) in Participants With EPP or XLP

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-08-31
Completion:: 2028-06-30

Conditions

Erythropoietic Protoporphyria

Interventions

DRUG

No Results Yet

NCT05879926 | RECRUITING | PHASE3

3960 participants

Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-10-18
Completion:: 2032-01-31

Conditions

Breast Cancer

Interventions

DRUG

No Results Yet

NCT05879822 | ACTIVE_NOT_RECRUITING | PHASE2

73 participants

A Study to Evaluate INCB099280 in Participants With Select Solid Tumors Who Are Immune Checkpoint Inhibitor Naive

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-10-30
Completion:: 2026-09-30

Conditions

Advanced Solid Tumor

Interventions

DRUG

No Results Yet

NCT05874271 | COMPLETED | NA

794 participants

Short Course Primaquine for the Radical Cure of P. Vivax - Papua New Guinea

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-08-07
Completion:: 2025-10-25

Conditions

Vivax Malaria
G6PD Deficiency

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT05868226 | RECRUITING | PHASE1/PHASE2

280 participants

PRE-ISPY Phase I/II Oncology Platform Program

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-02-15
Completion:: 2030-12-30

Conditions

HER2-positive Breast Cancer
Metastatic Cancer
Metastatic Breast Cancer
Metastatic
HER2-positive Metastatic Breast Cancer
HER2 Mutation-Related Tumors
HER-2 Protein Overexpression
HER2-negative Breast Cancer
Triple Negative Breast Cancer
HR Positive
Hormone Receptor-positive Breast Cancer
Estrogen Receptor Positive Tumor
Progesterone Receptor-positive Breast Cancer
Hormone Receptor Negative Breast Carcinoma
Solid Tumor
Solid Tumor, Adult
Solid Carcinoma
HER2 Low Breast Cancer
HER2 Low Breast Carcinoma
ER Positive Breast Cancer
PR-positive Breast Cancer
Minimal Residual Disease
Colo-rectal Cancer
Colon Cancer
Rectal Cancer
ctDNA Monitoring
Colorectal Neoplasms
Colonic Neoplasms
Rectal Neoplasms
Neoplasm, Residual
Adenocarcinoma of Colon
Adenocarcinoma

Interventions

DRUG

No Results Yet

NCT05866562 | RECRUITING | PHASE2

76 participants

Dupilumab in the Treatment of Pediatric Alopecia Areata

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2024-07-11
Completion:: 2029-03-31

Conditions

Alopecia Areata

Interventions

DRUG

No Results Yet

NCT05864144 | COMPLETED | PHASE1/PHASE2

98 participants

A Study of SNS-101 (Anti VISTA) Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-05-31
Completion:: 2026-06-02

Conditions

Solid Tumor, Adult
Advanced Solid Tumor
Head and Neck Cancer
Breast Cancer
Colon Cancer
Pancreatic Cancer
Gastric Cancer
Esophageal Cancer
Prostate Cancer
Uterine Cancer
Cervix Cancer
Ovarian Cancer
Kidney Cancer
Bladder Cancer
Thyroid Cancer
Melanoma
Sarcoma
Advanced Cancer
Metastatic Cancer
Refractory Cancer
Non Small Cell Lung Cancer
Merkel Cell Carcinoma

Interventions

DRUG

No Results Yet

NCT05862285 | RECRUITING | PHASE3

100 participants

A Rollover Study for Participants Previously Enrolled in a Genentech and/or F. Hoffman-La Roche Sponsored Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-06-01
Completion:: 2033-03-01

Conditions

Cancer

Interventions

DRUG

No Results Yet

NCT05860920 | TERMINATED

254 participants

Clinical Diagnostic Performance Evaluation of a Measles Rapid Test in Senegal

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-02
Start Date:: 2025-08-22
Completion:: 2026-06-16

Conditions

Measles

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05852509 | ACTIVE_NOT_RECRUITING | NA

32 participants

Digital Health Physical Activity Program for Older Family Care Partners of Patents With Heart Failure

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2024-07-01
Completion:: 2027-03-31

Conditions

Heart Failure
Caregiver Burden

Interventions

BEHAVIORAL

No Results Yet

NCT05851924 | RECRUITING | PHASE2

60 participants

A Study of NALIRIFOX in Combination With Radiation Therapy in People With Pancreatic Ductal Adenocarcinoma (PDAC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-05-12
Completion:: 2026-09-01

Conditions

Pancreatic Ductal Adenocarcinoma

Interventions

DRUG
COMBINATION_PRODUCT

No Results Yet

NCT05837767 | RECRUITING | NA

26 participants

A Study of Radiation Therapy to Treat Solid Tumor Cancer That Has Spread to Soft Tissue

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-07-24
Completion:: 2027-07-24

Conditions

Invasive Ductal Breast Carcinoma
Invasive Ductal Breast Carcinoma Stage IV
Lobular Breast Carcinoma
Lobular Breast Carcinoma Stage IV
Non Small Cell Lung Cancer
NSCLC
Gastrointestinal Cancer
Gastrointestinal Squamous Cell Cancer
Gastrointestinal Adenocarcinoma
Pancreatic Cancer
Bladder Cancer
Renal Cell Carcinoma
Melanoma
Sarcoma
Metastatic Solid Tumor

Interventions

RADIATION

No Results Yet

NCT05826054 | COMPLETED | PHASE1

15 participants

Montbretin Clinical Trial in Healthy Volunteers and Type 2 Diabetics

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-12-01
Completion:: 2025-11-25

Conditions

Type 2 Diabetes

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT05813964 | RECRUITING | PHASE3

524 participants

Efficacy, Acceptability and Safety of Event-driven HIV PrEP Using TAF/FTC in MSM in Thailand and France.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2024-06-05
Completion:: 2027-12-31

Conditions

HIV/AIDS

Interventions

DRUG

No Results Yet

NCT05796453 | COMPLETED | NA

470 participants

Post Market Clinical Follow-up (PMCF) Study of Clareon Vivity & Clareon PanOptix

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-09-19
Completion:: 2026-08-21

Conditions

Aphakia
Astigmatism
Presbyopia

Interventions

DEVICE

No Results Yet

NCT05785910 | COMPLETED | NA

14 participants

Adaptation of the Uniform Data Set for Telematic Administration

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2021-09-14
Completion:: 2022-01-31

Conditions

Dementia, Mild
Dementia of Alzheimer Type

Interventions

DIAGNOSTIC_TEST

No Results Yet