Clinical Trials

NCT05054439 | ACTIVE_NOT_RECRUITING | PHASE2

45 participants

A Clinical Study of SI-B001 in Combination With Paclitaxel/Docetaxel in the Treatment of Recurrent and Metastatic HNSCC

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2021-12-22

Completion:

2026-12-31

Conditions

• Head and Neck Squamous Cell Carcinoma

Interventions

• DRUG

No Results Yet

NCT05050916 | COMPLETED | PHASE2

998 participants

The Investigation of Vitamin D and Menstrual Cycles Trial, the inVitD Trial: A Phase II Clinical Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2023-03-17

Completion:

2024-06-07

Conditions

• Reproductive Issues

Interventions

• DIETARY_SUPPLEMENT
• OTHER

No Results Yet

NCT05049993 | ACTIVE_NOT_RECRUITING

76 participants

Pyrocarbon Clinical Follow-up Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2021-10-27

Completion:

2027-05-31

Conditions

• Osteoarthritis of the Shoulder
• Avascular Necrosis
• Traumatic Arthritis

Interventions

• DEVICE

No Results Yet

NCT05047172 | ACTIVE_NOT_RECRUITING | PHASE3

1683 participants

Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2022-08-02

Completion:

2027-01-31

Conditions

• Intracranial Arteriosclerosis
• Stroke

Interventions

• DRUG
• OTHER

No Results Yet

NCT05032092 | COMPLETED | NA

235 participants

Evaluation of Efficacy of Comprehensive Genomic Tumour Profiling (CGP) From Liquid and/or Tissue Biopsy in Patients With Locally Advanced and/or Metastatic Solid Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2021-11-24

Completion:

2026-04-14

Conditions

• Locally Advanced Carcinoma
• Metastatic Cancer

Interventions

• DIAGNOSTIC_TEST
• GENETIC

No Results Yet

NCT05026723 | ACTIVE_NOT_RECRUITING | NA

200 participants

Food as Medicine for HIV and Diabetes

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2021-10-04

Completion:

2026-10-31

Conditions

• Diabetes Mellitus, Type 2
• HIV Infections
• PreDiabetes

Interventions

• BEHAVIORAL

No Results Yet

NCT04996797 | COMPLETED | PHASE2

178 participants

A Phase 2 Safety and Efficacy Study of Tulisokibart (MK-7240/PRA023) in Subjects With Moderately to Severely Active Ulcerative Colitis (MK-7240-005)

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2021-07-14

Completion:

2023-06-06

Conditions

• Ulcerative Colitis

Interventions

• DRUG
• DEVICE
• OTHER

Results Available

NCT04977986 | COMPLETED | PHASE3

257 participants

Clinical Study of Cannabidiol in Children, Adolescents, and Young Adults With Fragile X Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2021-09-13

Completion:

2025-08-29

Conditions

• Fragile X Syndrome
• Fragile X Syndrome (FXS)

Interventions

• DRUG

No Results Yet

NCT04946851 | ENROLLING_BY_INVITATION

1400 participants

Addictions Neuroclinical Assessment (ANA)

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2021-08-12

Completion:

2031-12-31

Conditions

• Normal Physiology
• Alcohol Use Disorder

No Results Yet

NCT04933539 | ACTIVE_NOT_RECRUITING | PHASE2

14 participants

Subcutaneous Daratumumab, Once Weekly Carfilzomib, and Dexamethasone (DKd) in Patients With High-Risk Smoldering Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2022-10-31

Completion:

2026-08-31

Conditions

• Multiple Myeloma

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT04928677 | RECRUITING | PHASE1

50 participants

A Study of Codrituzumab in Children and Young Adults With Solid Tumors and Have Not Responded to Treatment or Have Come Back After Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2021-06-09

Completion:

2027-06-30

Conditions

• Primary Extra-cranial Solid Tumor
• Recurrent or Refractory Glypican 3 (GPC3)

Interventions

• DRUG

No Results Yet

NCT04926922 | COMPLETED

200 participants

PREVAIL VIIIa: Evaluation of Latent Tuberculosis Infection Screening Methods in People Living With Retroviral Infection in Liberia

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2021-07-27

Completion:

2026-04-30

Conditions

• Tuberculosis
• HIV

No Results Yet

NCT04866680 | ACTIVE_NOT_RECRUITING | NA

136 participants

Personalized Circulating DNA Follow-up in Melanoma (PERCIMEL)

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2023-01-31

Completion:

2027-11-30

Conditions

• Melanoma

Interventions

• PROCEDURE

No Results Yet

NCT04864886 | RECRUITING

300 participants

Metabolic Profiling of Immune Responses in Immune-mediated Diseases

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2021-08-10

Completion:

2027-06-30

Conditions

• Primary Immunodeficiency
• Psoriasis
• Atopic Dermatitis
• Immune-mediated Diseases

No Results Yet

NCT04837586 | COMPLETED | NA

99 participants

Self-Weighing for Adolescents Seeking Obesity Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2023-09-15

Completion:

2024-06-26

Conditions

• Adolescent Obesity

Interventions

• OTHER
• DEVICE

No Results Yet

NCT04829136 | RECRUITING | NA

100 participants

Sustained Oral Fiber Supplementation for Patients Undergoing Treatment for Hematological Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2022-06-22

Completion:

2027-07-31

Conditions

• Hematopoietic and Lymphatic System Neoplasm

Interventions

• DIETARY_SUPPLEMENT
• OTHER
• PROCEDURE

No Results Yet

NCT04789330 | COMPLETED | PHASE4

3626 participants

Norepinephrine vs Phenylephrine During General Anesthesia

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2021-07-01

Completion:

2022-04-01

Conditions

• Anesthesia
• Surgery
• Hypotension

Interventions

• DRUG

Results Available

NCT04786262 | RECRUITING | PHASE3

57 participants

A Safety, Tolerability, and Efficacy Study of VX-880 and VX-017 in Participants With Type 1 Diabetes

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2021-03-29

Completion:

2027-12-31

Conditions

• Diabetes Mellitus, Type 1
• Impaired Hypoglycemic Awareness
• Severe Hypoglycemia

Interventions

• BIOLOGICAL

No Results Yet

NCT04776694 | AVAILABLE

Compassionate Use or Expanded Access of Dupilumab

Study Type:

EXPANDED_ACCESS

Last Updated:

2026-09-01

Conditions

• Type 2 Inflammatory Disorders

Interventions

• DRUG

No Results Yet

NCT04750928 | RECRUITING | PHASE1/PHASE2

55 participants

Cyclin-Dependent Kinase (CDK)4/6 Inhibitor Abemaciclib for Neurofibromatosis Type I (NF1) Related Atypical Neurofibromas

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2021-11-29

Completion:

2028-12-31

Conditions

• Neurofibromatosis 1

Interventions

• DRUG

No Results Yet

NCT04737720 | COMPLETED

1 participants

Intravenous ACP-501 for Familial LCAT Deficiency (rhLCAT)

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2013-01-24

Completion:

2013-12-12

Conditions

• Familial LCAT Deficiency

Interventions

• DRUG

No Results Yet

NCT04729283 | COMPLETED

94 participants

Comparison of Quality of Life and Functionnal Resultats After Sigmodectomy Between Diverticulitis and Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2021-04-12

Completion:

2025-04-28

Conditions

• Sigmoid Cancer
• Sigmoid Diverticulosis

Interventions

• PROCEDURE

No Results Yet

NCT04657081 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

101 participants

Pharmacokinetics, Safety, and Efficacy of ASTX727 in Combination With Venetoclax in Acute Myeloid Leukemia (AML)

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2021-02-09

Completion:

2024-09-30

Conditions

• Acute Myeloid Leukemia

Interventions

• DRUG

No Results Yet

NCT04651296 | COMPLETED | PHASE2

142 participants

Compassion Meditation vs. Health Education for Veterans

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2022-01-04

Completion:

2025-08-21

Conditions

• Chronic Pain
• Stress Disorders, Posttraumatic
• Depression

Interventions

• BEHAVIORAL

Results Available

NCT04645160 | RECRUITING | PHASE1/PHASE2

31 participants

Evaluating Efficacy of Tivozanib (AV-951) in Biliary Tract Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2022-03-04

Completion:

2028-12-31

Conditions

• Cholangiocarcinoma
• Bile Duct Neoplasm
• Biliary Tract Malignancy

Interventions

• DRUG

No Results Yet

NCT04637503 | NOT_YET_RECRUITING | PHASE1/PHASE2

100 participants

4SCAR-T Therapy Targeting GD2, PSMA and CD276 for Treating Neuroblastoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2026-12-31

Completion:

2029-12-31

Conditions

• Neuroblastoma

Interventions

• BIOLOGICAL

No Results Yet

NCT04633811 | ACTIVE_NOT_RECRUITING | NA

14 participants

Effect of Weight Loss on Urinary Oxalate Excretion in Obese Calcium Oxalate Kidney Stone Formers

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2021-12-03

Completion:

2025-12-31

Conditions

• Kidney Stone

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT04631042 | RECRUITING

1100 participants

Developing Brain, Impulsivity and Compulsivity

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2022-09-30

Completion:

2030-12-31

Conditions

• Typical Development
• Obsessive Compulsive Disorder
• Conduct Disorder
• Attention Deficit Hyperactivity Disorder
• Autism Spectrum Disorder

No Results Yet

NCT04619004 | ACTIVE_NOT_RECRUITING | PHASE2

277 participants

HERTHENA-Lung01: Patritumab Deruxtecan in Subjects With Metastatic or Locally Advanced EGFR-mutated Non-Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2021-02-02

Completion:

2022-11-21

Conditions

• Non-Small Cell Lung Cancer Metastatic
• Non-Small Cell Lung Cancer With Mutation in Epidermal Growth Factor Receptor

Interventions

• DRUG

Results Available

NCT04609046 | RECRUITING | PHASE1

47 participants

Testing the Addition of Lenalidomide and Nivolumab to the Usual Treatment for Primary CNS Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2021-05-24

Completion:

2027-04-01

Conditions

• Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL

No Results Yet

NCT04595760 | ACTIVE_NOT_RECRUITING

231 participants

Factors Influencing Fertility or Pregnancy Health

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2020-10-19

Completion:

2030-12-31

Conditions

• Menstrual Cycles
• Conception
• Early Pregnancy Loss
• Pregnancy Outcomes

No Results Yet

NCT04570956 | TERMINATED | PHASE2

65 participants

Oral Tamoxifen vs. TamGel vs. Control in Women With Atypical Hyperplasia, Lobular Carcinoma In Situ, or Increased Breast Cancer Risk

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2021-07-26

Completion:

2024-10-15

Conditions

• Breast Atypical Hyperplasia
• Breast Lobular Carcinoma in Situ
• Breast Atypical Lobular Hyperplasia
• Breast Carcinoma

Interventions

• DRUG
• OTHER

Results Available

NCT04570423 | RECRUITING | PHASE2

40 participants

A Study to Evaluate the Safety and Pharmacokinetics of Eflapegrastim in Pediatric Participants With Solid Tumors or Lymphomas and Treated With Myelosuppressive Chemotherapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2021-05-20

Completion:

2027-10-31

Conditions

• Solid Tumors
• Lymphoma

Interventions

• DRUG

No Results Yet

NCT04557956 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

16 participants

Testing the Addition of the Anti-cancer Drug, Tazemetostat, to (Dabrafenib and Trametinib) for Metastatic Melanoma That Has Progressed on the Usual Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2021-08-19

Completion:

2025-10-15

Conditions

• Clinical Stage IV Cutaneous Melanoma AJCC v8
• Metastatic Melanoma

Interventions

• PROCEDURE
• DRUG

Results Available

NCT04553211 | COMPLETED | NA

663 participants

Expedited Partner Therapy and the HIV Prevention Cascade

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2022-04-25

Completion:

2024-04-30

Conditions

• HIV-1-infection
• Gonorrhea Male
• Chlamydia
• Partner Communication

Interventions

• BEHAVIORAL

Results Available

NCT04546399 | RECRUITING | PHASE2

461 participants

A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2020-12-17

Completion:

2028-06-30

Conditions

• Down Syndrome
• Recurrent B Acute Lymphoblastic Leukemia

Interventions

• RADIATION
• DRUG
• PROCEDURE
• BIOLOGICAL

No Results Yet

NCT04526665 | ACTIVE_NOT_RECRUITING | PHASE3

161 participants

Study of Elafibranor in Patients With Primary Biliary Cholangitis (PBC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2020-09-24

Completion:

2023-06-01

Conditions

• Primary Biliary Cirrhosis

Interventions

• DRUG

Results Available

NCT04521803 | COMPLETED | PHASE2

52 participants

High vs. Standard Dose Rifampicin for Effusive Tuberculous Pericarditis

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2022-01-10

Completion:

2026-03-26

Conditions

• Tuberculous Pericarditis
• HIV Status

Interventions

• DRUG

No Results Yet

NCT04501861 | COMPLETED | PHASE3

164 participants

Hemodynamic Effect of Norepinephrine Versus Vasopressin on the Pulmonary Circulation in Cardiac Surgery Patients:

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2020-11-05

Completion:

2023-08-22

Conditions

• Cardiac Disease

Interventions

• DRUG

Results Available

NCT04484272 | COMPLETED | NA

239 participants

A Stress and Pain Self-management m-Health App for Adult Outpatients With Sickle Cell Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2021-04-29

Completion:

2026-03-02

Conditions

• Sickle Cell Disease

Interventions

• BEHAVIORAL

No Results Yet