Clinical Trials

NCT05536141 | RECRUITING | PHASE1

362 participants

A Phase 1 Study of AB521 Monotherapy and Combination Therapies in Renal Cell Carcinoma and Other Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-10-26

Completion:

2029-03-31

Conditions

• Clear Cell Renal Cell Carcinoma
• Solid Tumors

Interventions

• DRUG

No Results Yet

NCT05523453 | COMPLETED | NA

70 participants

Examining Effects of a Therapeutic Focus on Positive Memories on Post-Trauma Health

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2023-03-23

Completion:

2025-02-19

Conditions

• Stress Disorders, Post-Traumatic
• Affect
• Memory

Interventions

• BEHAVIORAL

Results Available

NCT05497531 | RECRUITING | NA

15 participants

Pilot Comparing ctDNA IDV vs. SPV Sample in Pts Undergoing Biopsies for Hepatobiliary and Pancreatic Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-09-07

Completion:

2027-06-30

Conditions

• Hepatobiliary Cancer
• Pancreatic Cancer
• Hepatocellular Carcinoma
• Cholangiocarcinoma
• Ampullary Cancer
• Pancreatic Carcinoma

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05493215 | RECRUITING | PHASE2

28 participants

Imatinib TDM in GIST

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2024-03-26

Completion:

2027-12-31

Conditions

• Gastrointestinal Stromal Tumors

Interventions

• DRUG

No Results Yet

NCT05489783 | RECRUITING

50 participants

Glioma Developmental and HyperActive Ras Tumor (DHART) Board

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2022-07-29

Completion:

2027-07-31

Conditions

• Glioma

No Results Yet

NCT05489549 | RECRUITING

500 participants

Subclinical Transthyretin Cardiac Amyloidosis in V122I TTR Carriers

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2022-11-21

Completion:

2027-06-30

Conditions

• Amyloidosis, Hereditary
• Amyloidosis Cardiac
• Amyloidosis, Familial
• Transthyretin-Related (ATTR) Familial Amyloid Cardiomyopathy
• Transthyretin Gene Mutation

No Results Yet

NCT05473429 | RECRUITING | NA

215 participants

Characterization of Nociception Phenotype in Individuals With Intellectual Disability

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2026-03-27

Completion:

2026-10-06

Conditions

• Intellectual Disability

Interventions

• DEVICE

No Results Yet

NCT05466071 | RECRUITING

200 participants

Safety and Efficacy of TAF to Prevent MTCT of HBV in Middle/Late Pregnancies With High HBV DNA Load

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2021-06-01

Completion:

2024-05-30

Conditions

• Chronic Hepatitis b
• Pregnancy Related

No Results Yet

NCT05460273 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

119 participants

A Study of Dato-DXd in Chinese Patients With Advanced Non-Small Cell Lung Cancer, Triple-negative Breast Cancer and Other Solid Tumors (TROPION-PanTumor02)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-07-11

Completion:

2023-11-07

Conditions

• Carcinoma, Non-Small-Cell Lung
• Triple Negative Breast Cancer

Interventions

• DRUG

Results Available

NCT05458960 | TERMINATED | NA

3 participants

Impact of Basic Needs Assessment and Support to Improve Colposcopy Show Rate

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2025-03-28

Completion:

2025-08-28

Conditions

• Cervical Cancer

Interventions

• BEHAVIORAL

Results Available

NCT05440617 | RECRUITING

100 participants

Biorepository in Participants Who Undergo OTC for Gonadotoxic Therapy

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2022-07-22

Completion:

2041-09-21

Conditions

• Acute Ovarian Failure
• Infertility
• Early Menopause And Infertility In Females After Treatment For Childhood Cancer

No Results Yet

NCT05438849 | ACTIVE_NOT_RECRUITING

3214 participants

Improving Primary Care Access to Urinary Incontinence Treatment for Women Veterans

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2022-11-01

Completion:

2025-11-21

Conditions

• Urinary Incontinence

Interventions

• BEHAVIORAL
• COMBINATION_PRODUCT

No Results Yet

NCT05434130 | RECRUITING | PHASE1/PHASE2

178 participants

Modulating Exercise Dosage to Improve Concussion Recovery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-08-05

Completion:

2027-02-01

Conditions

• Concussion, Brain
• Treatment
• Aerobic Exercise
• Inflammation
• Depression, Anxiety

Interventions

• BEHAVIORAL

No Results Yet

NCT05426733 | ACTIVE_NOT_RECRUITING | PHASE3

180 participants

An Open-label Extension Study to Evaluate Long-term Efficacy and Safety of Odevixibat in Children With Biliary Atresia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-07-05

Completion:

2026-10-28

Conditions

• Biliary Atresia

Interventions

• DRUG

No Results Yet

NCT05424263 | COMPLETED | PHASE2

37 participants

Acetate and Age-associated Arterial Dysfunction

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-09-29

Completion:

2025-09-19

Conditions

• Aging
• Vascular Stiffness
• Vascular Dilation

Interventions

• DRUG

No Results Yet

NCT05422014 | COMPLETED | NA

117 participants

Upper Extremity Life Care Specialist (LCS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-10-17

Completion:

2025-05-23

Conditions

• Upper Extremity Trauma

Interventions

• BEHAVIORAL

No Results Yet

NCT05419024 | RECRUITING | PHASE2

50 participants

Imaging and Biopsy of People With HIV-1 Undergoing Analytic Treatment Interruption

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2023-01-09

Completion:

2029-08-01

Conditions

• HIV

Interventions

• OTHER

No Results Yet

NCT05418556 | RECRUITING | PHASE4

3944 participants

Tailored Versus Conventional AntiPlaTelet Strategy Intended After OPTIMIZEd Drug Eluting Stent

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-10-21

Completion:

2027-12-31

Conditions

• Coronary Artery Disease

Interventions

• DRUG

No Results Yet

NCT05417282 | COMPLETED | PHASE1

23 participants

MW151 and Whole-brain Radiotherapy in Patients With Intracranial Metastases

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-07-01

Completion:

2025-06-11

Conditions

• Cognitive Dysfunction, Cognitive Disorder

Interventions

• DRUG

Results Available

NCT05391321 | COMPLETED | NA

23 participants

Identification of the Most Suitable Questionnaire to Assess the Sexual Function of Women Living in France After Colorectal Cancer Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2023-05-12

Completion:

2024-05-20

Conditions

• Colorectal Cancer

Interventions

• OTHER

No Results Yet

NCT05388669 | ACTIVE_NOT_RECRUITING | PHASE3

418 participants

A Study of Lazertinib With Subcutaneous Amivantamab Compared With Intravenous Amivantamab in Participants With Epidermal Growth Factor Receptor (EGFR)-Mutated Advanced or Metastatic Non-small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-08-05

Completion:

2024-01-03

Conditions

• Advanced or Metastatic Non-small Cell Lung Cancer

Interventions

• DRUG

Results Available

NCT05379153 | RECRUITING | PHASE3

250 participants

Testing Laser Therapy for Treatment of Vaginal Dryness in Survivors of Breast Cancer, The Revitalize Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2026-04-21

Completion:

2026-09-30

Conditions

• Vaginal Atrophy
• Breast Carcinoma

Interventions

• DEVICE
• OTHER

No Results Yet

NCT05377281 | ACTIVE_NOT_RECRUITING | PHASE1

10 participants

Feasibility and Safety of autoloGous UncondItioneD pEripheral Nerve Tissue Delivery to the Substantia Nigra (GUIDE)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-07-07

Completion:

2026-12-30

Conditions

• Parkinson's Disease

Interventions

• PROCEDURE

No Results Yet

NCT05374460 | COMPLETED | NA

389 participants

Factors Affecting Sensory and Motor Learning

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-04-29

Completion:

2025-04-30

Conditions

• Basic Science

Interventions

• BEHAVIORAL

No Results Yet

NCT05329766 | ACTIVE_NOT_RECRUITING | PHASE2

332 participants

A Safety and Efficacy Study of Treatment Combinations With and Without Chemotherapy in Adult Participants With Advanced Upper Gastrointestinal Tract Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-06-10

Completion:

2027-01-31

Conditions

• Gastrointestinal Tract Malignancies

Interventions

• DRUG

No Results Yet

NCT05326932 | RECRUITING | NA

336 participants

Large Artery Occlusion Treated in Extended Time With Mechanical Thrombectomy Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-11-03

Completion:

2026-03-31

Conditions

• Acute Ischemic Stroke

Interventions

• PROCEDURE

No Results Yet

NCT05326412 | COMPLETED | PHASE2

49 participants

Mechanistic Study of the Effect of Itepekimab on Airway Inflammation in Patients With COPD

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-05-19

Completion:

2025-03-05

Conditions

• Chronic Obstructive Pulmonary Disease

Interventions

• DRUG

Results Available

NCT05307809 | RECRUITING | NA

40 participants

Cytokine Expression in Psoriasis Patients With and Without Joint Involvement

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-08-17

Completion:

2027-02-17

Conditions

• Psoriasis
• Psoriatic Arthritis

Interventions

• OTHER

No Results Yet

NCT05290701 | COMPLETED

235 participants

Evaluating Prenatal Exome Sequencing Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2022-02-21

Completion:

2025-12-12

Conditions

• Congenital Anomalies
• Mendelian Disorders
• Genetic Diseases, Inborn

No Results Yet

NCT05285748 | COMPLETED | PHASE2

258 participants

Comparing Self-paced Versus Moderate Intensity Physical Activity Recommendation for Midlife Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-03-15

Completion:

2026-06-18

Conditions

• Physical Inactivity

Interventions

• BEHAVIORAL

No Results Yet

NCT05281874 | COMPLETED | NA

1116 participants

Personalized Integrated Alcohol and Sexual Assault Prevention Among College Students

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-10-03

Completion:

2026-05-31

Conditions

• Alcohol Drinking
• Sexual Assault

Interventions

• BEHAVIORAL

No Results Yet

NCT05273957 | COMPLETED | NA

121 participants

A Model of Hospital-Territory Management Coordinated by a Case Manager to Improve the Care of Patients With Parkinsonism.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-03-29

Completion:

2025-01-30

Conditions

• Parkinson Disease
• Atypical Parkinsonism
• Secondary Parkinsonism
• Nurse-Patient Relations
• Nurse Physician Relations

Interventions

• OTHER

No Results Yet

NCT05272826 | RECRUITING | PHASE2

75 participants

Study of Iberdomide, Bortezomib, Dexamethasone With Isatuximab Added on Demand for ND-NTE MM Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2024-12-12

Completion:

2028-03-31

Conditions

• Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT05268913 | COMPLETED

30 participants

Towards Early Detection of Breast Cancer in High Risk Population

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2022-11-28

Completion:

2024-05-14

Conditions

• Breast Cancer

Interventions

• DIAGNOSTIC_TEST
• BIOLOGICAL

No Results Yet

NCT05250414 | COMPLETED | NA

18 participants

Single-Sided Deafness in the Medicare Population

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-06-27

Completion:

2025-08-11

Conditions

• Hearing Loss, Unilateral

Interventions

• DEVICE

Results Available

NCT05241860 | ACTIVE_NOT_RECRUITING | PHASE2

79 participants

Testing Interruption of Hormonal Medications in Patients Responding Exceptionally to Therapy for Metastatic Prostate Cancer, (A-DREAM)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-11-21

Completion:

2025-09-29

Conditions

• Castration-Sensitive Prostate Carcinoma
• Metastatic Prostate Carcinoma
• Stage IV Prostate Cancer AJCC v8
• Stage IVA Prostate Cancer AJCC v8
• Stage IVB Prostate Cancer AJCC v8

Interventions

• OTHER

Results Available

NCT05237986 | RECRUITING

60 participants

Cognitive Aftereffects of Neurotoxicity in Children and Young Adults With Relapsed/Refractory Hematologic Malignancies Who Receive CAR T-cell Therapy

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2025-06-23

Completion:

2028-09-01

Conditions

• Lymphoma
• Leukemia

No Results Yet

NCT05226494 | ACTIVE_NOT_RECRUITING | PHASE1

34 participants

Safety and Tolerability of Fb-PMT in Recurrent Glioblastoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-06-23

Completion:

2027-06-30

Conditions

• Glioma, Malignant

Interventions

• DRUG

No Results Yet

NCT05207670 | ACTIVE_NOT_RECRUITING | PHASE2

320 participants

A Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab Monotherapy in Participants With Select B-Cell Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-02-01

Completion:

2027-07-31

Conditions

• Non-Hodgkin Lymphoma

Interventions

• DRUG

No Results Yet

NCT05198323 | ACTIVE_NOT_RECRUITING | PHASE2

66 participants

A Study to Evaluate the Safety and Efficacy of LT3001 Drug Product in Subjects AIS Undergoing EVT

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-08-11

Completion:

2026-12-31

Conditions

• Acute Ischemic Stroke

Interventions

• DRUG

No Results Yet