Clinical Trials Updated in 2026

NCT05537363 | COMPLETED | NA

83 participants

Agility Training and Its Relations in Elderly Adults With and Without MCI

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2022-09-28
Completion:: 2025-03-13

Conditions

Elderly Adults
Mild Cognitive Impairment
Healthy

Interventions

OTHER

No Results Yet

NCT05537116 | COMPLETED | NA

149 participants

Evaluation of an Interactive Mobile Phone-Based Brief Intervention to Reduce Substance-Impaired Driving

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2022-10-18
Completion:: 2025-09-08

Conditions

Driving Impaired

Interventions

BEHAVIORAL

Results Available

NCT05536141 | RECRUITING | PHASE1

362 participants

A Phase 1 Study of AB521 Monotherapy and Combination Therapies in Renal Cell Carcinoma and Other Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2022-10-26
Completion:: 2029-03-31

Conditions

Clear Cell Renal Cell Carcinoma
Solid Tumors

Interventions

DRUG

No Results Yet

NCT05523453 | COMPLETED | NA

70 participants

Examining Effects of a Therapeutic Focus on Positive Memories on Post-Trauma Health

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2023-03-23
Completion:: 2025-02-19

Conditions

Stress Disorders, Post-Traumatic
Affect
Memory

Interventions

BEHAVIORAL

Results Available

NCT05497531 | RECRUITING | NA

15 participants

Pilot Comparing ctDNA IDV vs. SPV Sample in Pts Undergoing Biopsies for Hepatobiliary and Pancreatic Cancers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2022-09-07
Completion:: 2027-06-30

Conditions

Hepatobiliary Cancer
Pancreatic Cancer
Hepatocellular Carcinoma
Cholangiocarcinoma
Ampullary Cancer
Pancreatic Carcinoma

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05493215 | RECRUITING | PHASE2

28 participants

Imatinib TDM in GIST

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2024-03-26
Completion:: 2027-12-31

Conditions

Gastrointestinal Stromal Tumors

Interventions

DRUG

No Results Yet

NCT05489783 | RECRUITING

50 participants

Glioma Developmental and HyperActive Ras Tumor (DHART) Board

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-31
Start Date:: 2022-07-29
Completion:: 2027-07-31

Conditions

Glioma

No Results Yet

NCT05489549 | RECRUITING

500 participants

Subclinical Transthyretin Cardiac Amyloidosis in V122I TTR Carriers

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-31
Start Date:: 2022-11-21
Completion:: 2027-06-30

Conditions

Amyloidosis, Hereditary
Amyloidosis Cardiac
Amyloidosis, Familial
Transthyretin-Related (ATTR) Familial Amyloid Cardiomyopathy
Transthyretin Gene Mutation

No Results Yet

NCT05473429 | RECRUITING | NA

215 participants

Characterization of Nociception Phenotype in Individuals With Intellectual Disability

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2026-03-27
Completion:: 2026-10-06

Conditions

Intellectual Disability

Interventions

DEVICE

No Results Yet

NCT05466071 | RECRUITING

200 participants

Safety and Efficacy of TAF to Prevent MTCT of HBV in Middle/Late Pregnancies With High HBV DNA Load

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-31
Start Date:: 2021-06-01
Completion:: 2024-05-30

Conditions

Chronic Hepatitis b
Pregnancy Related

No Results Yet

NCT05460273 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

119 participants

A Study of Dato-DXd in Chinese Patients With Advanced Non-Small Cell Lung Cancer, Triple-negative Breast Cancer and Other Solid Tumors (TROPION-PanTumor02)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2022-07-11
Completion:: 2023-11-07

Conditions

Carcinoma, Non-Small-Cell Lung
Triple Negative Breast Cancer

Interventions

DRUG

Results Available

NCT05458960 | TERMINATED | NA

3 participants

Impact of Basic Needs Assessment and Support to Improve Colposcopy Show Rate

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-03-28
Completion:: 2025-08-28

Conditions

Cervical Cancer

Interventions

BEHAVIORAL

Results Available

NCT05440617 | RECRUITING

100 participants

Biorepository in Participants Who Undergo OTC for Gonadotoxic Therapy

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-31
Start Date:: 2022-07-22
Completion:: 2041-09-21

Conditions

Acute Ovarian Failure
Infertility
Early Menopause And Infertility In Females After Treatment For Childhood Cancer

No Results Yet

NCT05438849 | ACTIVE_NOT_RECRUITING

3214 participants

Improving Primary Care Access to Urinary Incontinence Treatment for Women Veterans

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-31
Start Date:: 2022-11-01
Completion:: 2025-11-21

Conditions

Urinary Incontinence

Interventions

BEHAVIORAL
COMBINATION_PRODUCT

No Results Yet

NCT05434130 | RECRUITING | PHASE1/PHASE2

178 participants

Modulating Exercise Dosage to Improve Concussion Recovery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2022-08-05
Completion:: 2027-02-01

Conditions

Concussion, Brain
Treatment
Aerobic Exercise
Inflammation
Depression, Anxiety

Interventions

BEHAVIORAL

No Results Yet

NCT05426733 | ACTIVE_NOT_RECRUITING | PHASE3

180 participants

An Open-label Extension Study to Evaluate Long-term Efficacy and Safety of Odevixibat in Children With Biliary Atresia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2022-07-05
Completion:: 2026-10-28

Conditions

Biliary Atresia

Interventions

DRUG

No Results Yet

NCT05424263 | COMPLETED | PHASE2

37 participants

Acetate and Age-associated Arterial Dysfunction

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2022-09-29
Completion:: 2025-09-19

Conditions

Aging
Vascular Stiffness
Vascular Dilation

Interventions

DRUG

No Results Yet

NCT05422014 | COMPLETED | NA

117 participants

Upper Extremity Life Care Specialist (LCS)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2022-10-17
Completion:: 2025-05-23

Conditions

Upper Extremity Trauma

Interventions

BEHAVIORAL

No Results Yet

NCT05419024 | RECRUITING | PHASE2

50 participants

Imaging and Biopsy of People With HIV-1 Undergoing Analytic Treatment Interruption

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2023-01-09
Completion:: 2029-08-01

Conditions

HIV

Interventions

OTHER

No Results Yet

NCT05418556 | RECRUITING | PHASE4

3944 participants

Tailored Versus Conventional AntiPlaTelet Strategy Intended After OPTIMIZEd Drug Eluting Stent

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2022-10-21
Completion:: 2027-12-31

Conditions

Coronary Artery Disease

Interventions

DRUG

No Results Yet

NCT05417282 | COMPLETED | PHASE1

23 participants

MW151 and Whole-brain Radiotherapy in Patients With Intracranial Metastases

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2022-07-01
Completion:: 2025-06-11

Conditions

Cognitive Dysfunction, Cognitive Disorder

Interventions

DRUG

Results Available

NCT05391321 | COMPLETED | NA

23 participants

Identification of the Most Suitable Questionnaire to Assess the Sexual Function of Women Living in France After Colorectal Cancer Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2023-05-12
Completion:: 2024-05-20

Conditions

Colorectal Cancer

Interventions

OTHER

No Results Yet

NCT05388669 | ACTIVE_NOT_RECRUITING | PHASE3

418 participants

A Study of Lazertinib With Subcutaneous Amivantamab Compared With Intravenous Amivantamab in Participants With Epidermal Growth Factor Receptor (EGFR)-Mutated Advanced or Metastatic Non-small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2022-08-05
Completion:: 2024-01-03

Conditions

Advanced or Metastatic Non-small Cell Lung Cancer

Interventions

DRUG

Results Available

NCT05379153 | RECRUITING | PHASE3

250 participants

Testing Laser Therapy for Treatment of Vaginal Dryness in Survivors of Breast Cancer, The Revitalize Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2026-04-21
Completion:: 2026-09-30

Conditions

Vaginal Atrophy
Breast Carcinoma

Interventions

DEVICE
OTHER

No Results Yet

NCT05377281 | ACTIVE_NOT_RECRUITING | PHASE1

10 participants

Feasibility and Safety of autoloGous UncondItioneD pEripheral Nerve Tissue Delivery to the Substantia Nigra (GUIDE)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2022-07-07
Completion:: 2026-12-30

Conditions

Parkinson's Disease

Interventions

PROCEDURE

No Results Yet

NCT05375812 | RECRUITING

85 participants

NIH Investigative Deep Phenotyping Study of Gulf War Veteran Health (Project NIH IN-DEPTH)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-31
Start Date:: 2023-04-16
Completion:: 2030-12-31

Conditions

Gulf War Illness

No Results Yet

NCT05374460 | COMPLETED | NA

389 participants

Factors Affecting Sensory and Motor Learning

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2022-04-29
Completion:: 2025-04-30

Conditions

Basic Science

Interventions

BEHAVIORAL

No Results Yet

NCT05372627 | NOT_YET_RECRUITING

1000 participants

NHLBI-Emory Advanced Cardiac CT Reconstruction

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-31
Start Date:: 2026-09-03
Completion:: 2031-01-30

Conditions

Structural Heart Disease

No Results Yet

NCT05329766 | ACTIVE_NOT_RECRUITING | PHASE2

332 participants

A Safety and Efficacy Study of Treatment Combinations With and Without Chemotherapy in Adult Participants With Advanced Upper Gastrointestinal Tract Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2022-06-10
Completion:: 2027-01-31

Conditions

Gastrointestinal Tract Malignancies

Interventions

DRUG

No Results Yet

NCT05326932 | RECRUITING | NA

336 participants

Large Artery Occlusion Treated in Extended Time With Mechanical Thrombectomy Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2022-11-03
Completion:: 2026-03-31

Conditions

Acute Ischemic Stroke

Interventions

PROCEDURE

No Results Yet

NCT05326412 | COMPLETED | PHASE2

49 participants

Mechanistic Study of the Effect of Itepekimab on Airway Inflammation in Patients With COPD

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2022-05-19
Completion:: 2025-03-05

Conditions

Chronic Obstructive Pulmonary Disease

Interventions

DRUG

Results Available

NCT05307809 | RECRUITING | NA

40 participants

Cytokine Expression in Psoriasis Patients With and Without Joint Involvement

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2022-08-17
Completion:: 2027-02-17

Conditions

Psoriasis
Psoriatic Arthritis

Interventions

OTHER

No Results Yet

NCT05290701 | COMPLETED

235 participants

Evaluating Prenatal Exome Sequencing Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-31
Start Date:: 2022-02-21
Completion:: 2025-12-12

Conditions

Congenital Anomalies
Mendelian Disorders
Genetic Diseases, Inborn

No Results Yet

NCT05285748 | COMPLETED | PHASE2

258 participants

Comparing Self-paced Versus Moderate Intensity Physical Activity Recommendation for Midlife Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2022-03-15
Completion:: 2026-06-18

Conditions

Physical Inactivity

Interventions

BEHAVIORAL

No Results Yet

NCT05281874 | COMPLETED | NA

1116 participants

Personalized Integrated Alcohol and Sexual Assault Prevention Among College Students

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2022-10-03
Completion:: 2026-05-31

Conditions

Alcohol Drinking
Sexual Assault

Interventions

BEHAVIORAL

No Results Yet

NCT05273957 | COMPLETED | NA

121 participants

A Model of Hospital-Territory Management Coordinated by a Case Manager to Improve the Care of Patients With Parkinsonism.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2021-03-29
Completion:: 2025-01-30

Conditions

Parkinson Disease
Atypical Parkinsonism
Secondary Parkinsonism
Nurse-Patient Relations
Nurse Physician Relations

Interventions

OTHER

No Results Yet

NCT05272826 | RECRUITING | PHASE2

75 participants

Study of Iberdomide, Bortezomib, Dexamethasone With Isatuximab Added on Demand for ND-NTE MM Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2024-12-12
Completion:: 2028-03-31

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT05268913 | COMPLETED

30 participants

Towards Early Detection of Breast Cancer in High Risk Population

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-31
Start Date:: 2022-11-28
Completion:: 2024-05-14

Conditions

Breast Cancer

Interventions

DIAGNOSTIC_TEST
BIOLOGICAL

No Results Yet

NCT05250414 | COMPLETED | NA

18 participants

Single-Sided Deafness in the Medicare Population

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2022-06-27
Completion:: 2025-08-11

Conditions

Hearing Loss, Unilateral

Interventions

DEVICE

Results Available

NCT05241860 | ACTIVE_NOT_RECRUITING | PHASE2

79 participants

Testing Interruption of Hormonal Medications in Patients Responding Exceptionally to Therapy for Metastatic Prostate Cancer, (A-DREAM)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2022-11-21
Completion:: 2025-09-29

Conditions

Castration-Sensitive Prostate Carcinoma
Metastatic Prostate Carcinoma
Stage IV Prostate Cancer AJCC v8
Stage IVA Prostate Cancer AJCC v8
Stage IVB Prostate Cancer AJCC v8

Interventions

OTHER

Results Available