Clinical Trials

NCT04881240 | RECRUITING | PHASE1

60 participants

Study of CD19 Allogeneic Memory T-cell Therapy for Relapsed/Refractory CD19+ Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2024-02-14

Completion:

2027-07-01

Conditions

• Acute Lymphoblastic Leukemia, in Relapse
• Acute Lymphoblastic Leukemia, Refractory
• Pediatric ALL

Interventions

• BIOLOGICAL
• DRUG
• DEVICE
• PROCEDURE

No Results Yet

NCT04877288 | RECRUITING | PHASE3

102 participants

A Study to Evaluate the Benefits and Risks of Conversion of Existing Adolescent Kidney Transplant Recipients Aged 12 to <18 Years to a Belatacept-based Immunosuppressive Regimen as Compared to Continuation of a Calcineurin Inhibitor-based Regimen, and Their Adherence to Immunosuppressive Medications

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-07-21

Completion:

2032-12-30

Conditions

• Renal Allograft Recipients

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT04868344 | COMPLETED | PHASE1

61 participants

A Study of MRG003 in Patients With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2018-05-09

Completion:

2021-03-29

Conditions

• Advanced Solid Tumors

Interventions

• DRUG

No Results Yet

NCT04839614 | RECRUITING | NA

30 participants

Concurrent Laparoscopic Hysterectomy and Weight Loss Surgery in Obese Patients With Endometrial Carcinoma or Endometrial Intraepithelial Neoplasia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-08-01

Completion:

2028-06-30

Conditions

• Endometrial Carcinoma
• Obesity
• EIN
• Endometrial Intraepithelial Neoplasia
• Endometrial Cancer Stage I

Interventions

• OTHER

No Results Yet

NCT04827368 | COMPLETED

292 participants

Volatile Organic Compounds (VOCs) in Active Inflammatory Bowel Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2021-03-22

Completion:

2026-06-30

Conditions

• IBD
• Crohn Disease
• Ulcerative Colitis

Interventions

• OTHER

No Results Yet

NCT04765696 | ACTIVE_NOT_RECRUITING

1964 participants

Prospective RELOC-AGE: How Do Housing Choices and Relocation Matter for Active Ageing?

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2021-03-01

Completion:

2028-12-31

Conditions

• Active Ageing

Interventions

• OTHER

No Results Yet

NCT04765683 | COMPLETED

220 participants

Video, Telephone or Face-to-face Surgical Consultations: a Survey of Patients' and Surgeons' Views

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2021-08-20

Completion:

2021-10-25

Conditions

• Surgery

Interventions

• OTHER

No Results Yet

NCT04751786 | ACTIVE_NOT_RECRUITING | PHASE1

15 participants

Dose Escalation Study of Immunomodulatory Nanoparticles

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-01-11

Completion:

2026-12-31

Conditions

• Advanced Solid Tumor

Interventions

• DRUG

No Results Yet

NCT04736173 | ACTIVE_NOT_RECRUITING | PHASE2

169 participants

Study Evaluating Effectiveness and Safety of Zimberelimab and Domvanalimab in Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-02-08

Completion:

2027-05-31

Conditions

• Non Small Cell Lung Cancer
• Nonsquamous Non Small Cell Lung Cancer
• Squamous Non Small Cell Lung Cancer
• Lung Cancer

Interventions

• DRUG

No Results Yet

NCT04708470 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

55 participants

A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-10-05

Completion:

2026-11-30

Conditions

• Oropharyngeal Cancer
• Neck Cancer
• Human Papillomavirus
• HPV
• Anal Cancer
• Cervical Cancer
• Penile Cancer
• Vulvar Cancer
• Vaginal Cancer
• Colon Cancer

Interventions

• DRUG

No Results Yet

NCT04700748 | COMPLETED | NA

150 participants

Diffusion-weighted MRI to Predict Treatment Response in Stereotactic Radiotherapy of Central Nervous System (CNS) Metastases

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2020-12-28

Completion:

2024-04-30

Conditions

• Radiotherapy
• Brain Metastases
• Sensitivity
• Radionecrosis

Interventions

• RADIATION

No Results Yet

NCT04685200 | RECRUITING

143 participants

Unraveling the Mechanisms Underlying Primary Sclerosing Cholangitis Through a Multidisciplinary, Integrative Research Approach

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2023-03-31

Completion:

2026-10-31

Conditions

• Primary Sclerosing Cholangitis

No Results Yet

NCT04673331 | COMPLETED

50 participants

Comparison of Physical Activity, Exercise Capacity, Quality of Life, Cognitive Function and Coronavirus Phobia Levels of Adult Cystic Fibrosis Patients With Healthy Individuals With Telerehabilitation

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2021-01-05

Completion:

2021-08-05

Conditions

• Cystic Fibrosis

Interventions

• OTHER

No Results Yet

NCT04663906 | COMPLETED

148 participants

Oral Isotretinoin and Covid-19 Infection

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2021-01-15

Completion:

2021-09-15

Conditions

• Isotretinoin Adverse Reaction
• Covid19

No Results Yet

NCT04641351 | ACTIVE_NOT_RECRUITING | PHASE4

150 participants

Corticosteroid Meniscectomy Randomized Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-05-27

Completion:

2026-08-01

Conditions

• Osteoarthritis, Knee
• Meniscus Tear
• Meniscus; Degeneration
• Synovitis

Interventions

• DRUG

No Results Yet

NCT04628481 | TERMINATED | PHASE2

289 participants

A Study of Oral Ladarixin in Recent Onset Type 1 Diabetes and a Low Residual β-cell Function

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-01-12

Completion:

2025-03-31

Conditions

• Recent Onset type1 Diabetes

Interventions

• DRUG

Results Available

NCT04544904 | COMPLETED | NA

356 participants

The Technology, Exercise Programming, and Activity Prescription for Enhanced Mobility (TEAM) Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-06-18

Completion:

2026-06-01

Conditions

• Osteo Arthritis Knee
• Osteoarthritis
• Hip Arthritis

Interventions

• DEVICE

No Results Yet

NCT04538664 | ACTIVE_NOT_RECRUITING | PHASE3

308 participants

A Study of Combination Amivantamab and Carboplatin-Pemetrexed Therapy, Compared With Carboplatin-Pemetrexed, in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Characterized by Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2020-10-13

Completion:

2023-05-03

Conditions

• Carcinoma, Non-Small-Cell Lung

Interventions

• DRUG

Results Available

NCT04505371 | COMPLETED | NA

235 participants

Improving the Reach & Effectiveness of Smoking Cessation Services Targeted to Veterans Living With HIV

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-06-04

Completion:

2025-03-31

Conditions

• HIV Infections
• Smoking
• Smoking Cessation

Interventions

• BEHAVIORAL

Results Available

NCT04495660 | RECRUITING | NA

80 participants

Restauration of the Auditory and Cognitive Functions in Cochlear Implanted Deaf Children in fNIRS

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2020-05-29

Completion:

2027-06-03

Conditions

• Deafness

Interventions

• DEVICE
• BEHAVIORAL

No Results Yet

NCT04488536 | ACTIVE_NOT_RECRUITING

10000 participants

Management and Outcomes of Patients Admitted to Coronary Care Units, Depending on Degree of Frailty and Comorbidities

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2020-07-29

Completion:

2021-12-31

Conditions

• Myocardial Infarction
• Frailty

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04455334 | COMPLETED | NA

54 participants

Error-augmented Walking on Gait Performance and Brain Activities in Stroke

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2020-07-13

Completion:

2022-12-01

Conditions

• Healthy
• Stroke

Interventions

• OTHER

No Results Yet

NCT04452344 | COMPLETED | PHASE3

1815 participants

Opioid Analgesic Reduction Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-01-04

Completion:

2023-07-07

Conditions

• Opioid Use

Interventions

• DRUG

Results Available

NCT04449549 | RECRUITING | PHASE2

82 participants

Rapid Analysis and Response Evaluation of Combination Anti-Neoplastic Agents in Rare Tumors (RARE CANCER) Trial: RARE 1 Nilotinib and Paclitaxel

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2020-08-24

Completion:

2027-04-02

Conditions

• Neoplasms

Interventions

• DRUG

No Results Yet

NCT04430426 | ENROLLING_BY_INVITATION | NA

4 participants

Heterozygous Individuals for AGXT and Kidney Stones

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2027-07-01

Completion:

2031-08-01

Conditions

• Kidney Stone
• Urolithiasis, Calcium Oxalate

Interventions

• OTHER

No Results Yet

NCT04416269 | TERMINATED | PHASE4

85 participants

Oral Anti Diabetic Agents in the Hospital

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2020-08-07

Completion:

2025-04-11

Conditions

• Diabetes Mellitus

Interventions

• DRUG
• DEVICE

Results Available

NCT04401449 | COMPLETED

202 participants

Cardiopulmonary Inflammation and Multi-System Imaging During the Clinical Course of COVID-19 Infection in Asymptomatic and Symptomatic Persons

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2020-05-21

Completion:

2023-08-31

Conditions

• Acute and Long Term Effects of COVID-19 on Systemic Inflammation
• Acute and Long Term Effects of COVID-19 on Lung Function
• Acute and Long Term Effects of COVID-19 on Cardiac Function
• Acute and Long Term Effects of COVID-19 on Kidney Function
• Acute and Long Term Effects of COVID-19 on Brain Function

No Results Yet

NCT04388332 | RECRUITING | NA

60 participants

ACDF Using Structural Allograft vs. Tritanium C

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2020-08-20

Completion:

2026-12-31

Conditions

• Degenerative Disc Disease

Interventions

• PROCEDURE
• DEVICE

No Results Yet

NCT04376489 | COMPLETED | NA

114 participants

Project MARS: Mobile-Assistance for Regulating Smoking

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2020-08-27

Completion:

2023-10-20

Conditions

• Current Smoker
• Tobacco Smoking

Interventions

• BEHAVIORAL

Results Available

NCT04370093 | COMPLETED | PHASE4

29 participants

Pathogenesis of Uric Acid Nephrolithiasis: Role of Pioglitazone/Weight Loss

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2019-10-17

Completion:

2025-05-28

Conditions

• Nephrolithiasis, Uric Acid

Interventions

• DRUG
• BEHAVIORAL
• OTHER

Results Available

NCT04355195 | RECRUITING

18100 participants

Quality Contract: Prevention of Postoperative Delirium in the Care of Older Patients (QV-POD-2)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2020-04-20

Completion:

2028-06-30

Conditions

• Delirium in Old Age

No Results Yet

NCT04354077 | RECRUITING | NA

3 participants

Deep Brain Stimulation Effects In Patients With Opioid Use Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-02-07

Completion:

2029-01-31

Conditions

• Opioid-use Disorder

Interventions

• DEVICE

No Results Yet

NCT04349475 | ACTIVE_NOT_RECRUITING | NA

40 participants

Therapeutic Omegas for Triglyceride Suppression

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-11-29

Completion:

2026-04-30

Conditions

• Pregnancy

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT04308278 | RECRUITING | PHASE4

88 participants

Study to Evaluate the Efficacy of 2LEBV® and 2LXFS® on Asthenia in Patients With an Epstein-Barr Virus Infection

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-01-22

Completion:

2028-08-22

Conditions

• EBV Infection

Interventions

• DRUG

No Results Yet

NCT04298541 | WITHDRAWN | PHASE2

0 participants

Direct Comparison of Ga-68-DOTATATE and Ga-68-DOTATOC

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2026-08-31

Completion:

2026-08-31

Conditions

• Meningioma

Interventions

• DRUG

No Results Yet

NCT04269213 | COMPLETED | PHASE2

21 participants

CPX-351 for the Treatment of Secondary Acute Myeloid Leukemia in Patients Younger Than 60 Years Old

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-07-29

Completion:

2025-05-27

Conditions

• Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome
• Acute Myeloid Leukemia With Myelodysplasia-Related Changes
• Secondary Acute Myeloid Leukemia
• Therapy-Related Acute Myeloid Leukemia

Interventions

• DRUG

Results Available

NCT04267861 | ACTIVE_NOT_RECRUITING

232 participants

M7824 Related Adverse Effects in Adults With Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2020-01-28

Completion:

2027-11-01

Conditions

• Neoplasms
• Skin Neoplasms

No Results Yet

NCT04249843 | TERMINATED | PHASE1

109 participants

Study of Safety, Pharmacokinetics, and Antitumor Activity of BGB-3245 in Participants With Advanced or Refractory Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2020-02-10

Completion:

2025-08-08

Conditions

• Solid Tumor
• B-Raf Mutation-Related Tumors

Interventions

• DRUG

Results Available

NCT04201873 | COMPLETED | PHASE1

46 participants

Pembrolizumab and a Vaccine (ATL-DC) for the Treatment of Surgically Accessible Recurrent Glioblastoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2020-01-08

Completion:

2026-08-13

Conditions

• Recurrent Glioblastoma

Interventions

• BIOLOGICAL
• OTHER
• DRUG

No Results Yet

NCT04190420 | ACTIVE_NOT_RECRUITING

310 participants

The Transition From Hypertension to Hypertensive Heart Disease and Heart Failure, the PREFERS Hypertension Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2018-10-01

Completion:

2030-09-30

Conditions

• Hypertension
• Heart Failure
• Hypertensive Heart Disease
• Diastolic Dysfunction

No Results Yet