Study of Safety, Pharmacokinetics, and Antitumor Activity of BGB-3245 in Participants With Advanced or Refractory Tumors
NCT04249843 · Status: TERMINATED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 109
Last updated 2025-09-11
Summary
The purpose of this study is to evaluate the safety, tolerability, and antitumor activity of BGB-3245 in participants with advanced or refractory solid tumors
Conditions
- Solid Tumor
- B-Raf Mutation-Related Tumors
Interventions
- DRUG
-
BGB-3245
administered orally (PO)
Sponsors & Collaborators
-
MapKure, LLC
lead INDUSTRY
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SEQUENTIAL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-02-17
- Primary Completion
- 2025-08-04
- Completion
- 2025-08-04
- FDA Drug
- Yes
Countries
- United States
- Australia
Study Locations
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