Clinical Trials

NCT06741969 | ACTIVE_NOT_RECRUITING | PHASE3

655 participants

Nipocalimab in Moderate to Severe Sjogren's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-12-04

Completion:

2028-01-01

Conditions

• Sjogrens Syndrome

Interventions

• DRUG

No Results Yet

NCT06736574 | RECRUITING | PHASE3

1800 participants

Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-12-19

Completion:

2027-09-30

Conditions

• Heart Failure
• Heart Failure With Reduced Ejection Fraction

Interventions

• DRUG

No Results Yet

NCT06735833 | RECRUITING | NA

70 participants

MMA Embolization for Refractory Chronic Migraine

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2025-04-23

Completion:

2026-12-25

Conditions

• Migraine Disorders

Interventions

• DEVICE

No Results Yet

NCT06735534 | RECRUITING | NA

376 participants

Repeat Ablation of Persistent Atrial Fibrillation, Including Mitral Isthmus Catheter Ablation, With the FARAPULSE Pulsed Field Ablation System

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2025-06-03

Completion:

2027-04-30

Conditions

• Persistent Atrial Fibrillation

Interventions

• DEVICE

No Results Yet

NCT06730633 | COMPLETED | NA

173 participants

Collaborate and Leverage Evidence in African American Rural Network

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2025-02-22

Completion:

2026-08-14

Conditions

• Cardiovascular Diseases

Interventions

• BEHAVIORAL

No Results Yet

NCT06729164 | ACTIVE_NOT_RECRUITING | NA

150 participants

Strategic and Interactive Signing Instruction Experiment

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2025-04-01

Completion:

2026-09-30

Conditions

• Sign Language Skills
• Teacher Practice

Interventions

• BEHAVIORAL

No Results Yet

NCT06717789 | COMPLETED | NA

74 participants

Compex SP8.0 - Symptomatic Treatment of Musculoskeletal Pain

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2025-04-01

Completion:

2025-12-31

Conditions

• Musculoskeletal Conditions
• Musculoskeletal Pain

Interventions

• DEVICE

No Results Yet

NCT06717347 | RECRUITING | PHASE3

1046 participants

A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2025-01-27

Completion:

2029-07-02

Conditions

• Diffuse Large B-Cell Lymphoma

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT06714097 | RECRUITING | NA

20 participants

Application of Digital Twins' Technology in Patients Who Had a Stroke, With Moyamoya Disease and With Cerebral Amyloid Angiopathy (CAA) During the Secondary Prevention Phase: A Proof of Concept Using a Randomized Control Trial (Clinical Study 6, STRATIF-AI Project)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2026-10-31

Completion:

2027-10-31

Conditions

• Stroke
• Moyamoya Disease
• Cerebral Amyloid Angiopathy

Interventions

• DEVICE
• OTHER

No Results Yet

NCT06713382 | RECRUITING | PHASE2

96 participants

Evaluating the Efficacy and Safety of Saline Irrigation as an Add-On Therapy for Retained Pleural Infections [LYTICS +]

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2025-04-10

Completion:

2026-11-20

Conditions

• Pleural Effusion Associated With Pulmonary Infection
• Pleural Effusion Disorder
• Pleural Effusions

Interventions

• COMBINATION_PRODUCT

No Results Yet

NCT06712836 | COMPLETED | PHASE2

239 participants

A Phase 2b Study to Examine the Safety and Efficacy of Once-Weekly MET097 in Adults With Obesity or Overweight

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-10-09

Completion:

2025-07-03

Conditions

• Obesity
• Overweight or Obesity

Interventions

• DRUG

Results Available

NCT06706674 | RECRUITING | PHASE3

160 participants

Multicenter Study of Lumateperone for the Treatment of Irritability Associated With Autism Spectrum Disorder (ASD) in Pediatric Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-12-06

Completion:

2027-06-21

Conditions

• Irritability Associated With Autism Spectrum Disorder

Interventions

• DRUG

No Results Yet

NCT06704672 | RECRUITING | NA

270 participants

Clinical Study to Evaluate the Impact of the Accu-Chek SmartGuide CGM Solution on the Mean Change in Time in Range Compared With Self-Monitoring of Blood Glucose in Participants With Type 1 and Type 2 Diabetes Mellitus

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2025-04-14

Completion:

2026-11-15

Conditions

• Type 1 Diabetes Mellitus
• Type 2 Diabetes Mellitus

Interventions

• DEVICE

No Results Yet

NCT06700447 | ACTIVE_NOT_RECRUITING | NA

2163 participants

Protecting Against HIV Vaccine Misinformation With Adolescent Girls and Young Women in South Africa

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2025-07-24

Completion:

2025-10-16

Conditions

• Misinformation
• HIV Vaccine

Interventions

• BEHAVIORAL

Results Available

NCT06693271 | RECRUITING | NA

240 participants

Investigating the Combined Effects of Protein, Blueberries, and Exercise on Cardiovascular Health and Frailty in Older Nova Scotians

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2025-12-15

Completion:

2028-06-30

Conditions

• Cardiovascular Disease
• Frailty

Interventions

• DIETARY_SUPPLEMENT
• BEHAVIORAL

No Results Yet

NCT06690827 | RECRUITING | PHASE1

30 participants

Clinical Trial of CD123-targeted CAR-NK Therapy for Relapse/Refractory AML or BPDCN

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-12-12

Completion:

2027-06-30

Conditions

• AML (Acute Myeloid Leukemia)
• BPDCN (Blastic Plasmacytoid Dendritic Cell Neoplasm)

Interventions

• DRUG

No Results Yet

NCT06690398 | RECRUITING | PHASE3

160 participants

Multicenter Study of Lumateperone for the Treatment of Irritability Associated With Autism Spectrum Disorder in Pediatric Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-11-22

Completion:

2027-06-21

Conditions

• Irritability Associated With Autism Spectrum Disorder

Interventions

• DRUG

No Results Yet

NCT06687772 | RECRUITING | PHASE2

36 participants

CNS-Relapse Prevention in High-Risk Diffuse Large B-cell Lymphoma With Thiotepa-based Autologous Stem Cell Transplant

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2025-01-16

Completion:

2028-07-31

Conditions

• Diffuse Large B Cell Lymphoma

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT06684483 | RECRUITING

72 participants

The Impact of Heavy Alcohol Use on Saliva and Oral Health

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2025-01-09

Completion:

2026-12-01

Conditions

• Alcohol Use Disorder
• Alcohol Dependence

No Results Yet

NCT06683755 | RECRUITING | PHASE1/PHASE2

30 participants

Phase I/IIa Dose Finding Study of Triplet Regimen of Relatlimab Ipilimumab and NIvolumab in First Line Therapy of Metastatic Melanoma (TRINITY)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-12-31

Completion:

2030-08-16

Conditions

• Melanoma

Interventions

• DRUG

No Results Yet

NCT06682780 | RECRUITING | PHASE1/PHASE2

320 participants

A Phase I/II Study of LM-2417 in Subjects With Advanced Solid Tumours

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2025-09-17

Completion:

2028-12-25

Conditions

• Advanced Solid Tumor

Interventions

• DRUG

No Results Yet

NCT06680830 | RECRUITING | PHASE2

150 participants

A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2025-01-17

Completion:

2027-12-31

Conditions

• Parkinson Disease
• Parkinson
• Idiopathic Parkinson Disease
• Early Parkinson Disease (Early PD)
• Parkinson Disease, Idiopathic

Interventions

• DRUG
• OTHER

No Results Yet

NCT06667908 | RECRUITING | PHASE2

130 participants

A Study of JNJ-90301900 in Combination With Chemoradiation Followed by Consolidation Immunotherapy for Non-Small Cell Lung Cancer (NSCLC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-12-06

Completion:

2028-12-31

Conditions

• Carcinoma, Non-Small-Cell Lung

Interventions

• DRUG
• BIOLOGICAL
• RADIATION

No Results Yet

NCT06667700 | RECRUITING | PHASE3

3082 participants

A Clinical Study of Molnupiravir to Prevent Severe Illness From Coronavirus Disease 2019 (COVID-19) in People Who Are High Risk (MK-4482-023)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-12-02

Completion:

2031-01-26

Conditions

• Coronavirus Disease (COVID-19)

Interventions

• DRUG

No Results Yet

NCT06667076 | RECRUITING | PHASE2

480 participants

A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-12-16

Completion:

2029-05-23

Conditions

• Carcinoma, Non-Small-Cell Lung

Interventions

• DRUG

No Results Yet

NCT06666985 | RECRUITING | PHASE4

700 participants

Intrathecal Morphine for Postoperative Analgesia in Major Laparoscopic Abdominal Surgery, a IMPACT-Scope Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-12-16

Completion:

2026-09-30

Conditions

• Patients Undergoing Major Laparoscopic Abdominal Surgery

Interventions

• DRUG

No Results Yet

NCT06664788 | RECRUITING | NA

108 participants

A Study of ETHIZIA Versus SURGICEL Original in Controlling Soft Tissue Bleeding During Open Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2025-04-16

Completion:

2026-09-28

Conditions

• Hemostasis
• Hemostatic Techniques

Interventions

• DEVICE

No Results Yet

NCT06663332 | RECRUITING | PHASE3

196 participants

A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-10-29

Completion:

2031-12-12

Conditions

• Crohns Disease
• Colitis, Ulcerative
• Arthritis, Psoriatic
• Arthritis, Juvenile

Interventions

• DRUG

No Results Yet

NCT06663319 | RECRUITING | PHASE1

260 participants

A Study of JNJ-89402638 for Metastatic Colorectal and Gastric Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-10-15

Completion:

2028-02-25

Conditions

• Colorectal Neoplasms
• Gastrointestinal Neoplasms

Interventions

• DRUG

No Results Yet

NCT06662786 | RECRUITING | PHASE3

1000 participants

A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-10-18

Completion:

2028-12-15

Conditions

• Colorectal Neoplasms

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT06660563 | ACTIVE_NOT_RECRUITING | PHASE1

19 participants

A Study of JNJ-80948543 in Combination With Other CD3 T-Cell Engagers in Participants With Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma (R/R B-Cell NHL)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-10-22

Completion:

2026-01-19

Conditions

• Lymphoma, Non-Hodgkin

Interventions

• DRUG

No Results Yet

NCT06659536 | RECRUITING | NA

53 participants

Cefar URO - Symptomatic Treatment of Overactive Bladder

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2026-01-19

Completion:

2026-10-31

Conditions

• Overactive Bladder (OAB)
• Refractory Overactive Bladder
• Urinary Urgency and Frequency

Interventions

• DEVICE

No Results Yet

NCT06656884 | ACTIVE_NOT_RECRUITING

524 participants

FARAPULSE Workflow Assessment Registry

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2025-05-06

Completion:

2027-02-15

Conditions

• Atrial Fibrillation (AF)

No Results Yet

NCT06655883 | RECRUITING | PHASE3

300 participants

A Study of Suvorexant (MK-4305) for the Treatment of Insomnia Disorder in Participants With Opioid Use Disorder (MK-4305-098)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2025-10-09

Completion:

2027-06-24

Conditions

• Insomnia

Interventions

• DRUG

No Results Yet

NCT06651229 | RECRUITING | PHASE1

155 participants

A Study of JNJ-90189892 for Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Neoplasms

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2025-03-21

Completion:

2027-08-05

Conditions

• Leukemia, Myeloid, Acute
• Myelodysplastic Neoplasms

Interventions

• DRUG

No Results Yet

NCT06648889 | RECRUITING | PHASE2

28 participants

Isatuximab in Adult Patients With Cytologic or Molecular Relapsed/Refractory CD38 Positive T-cell Acute Lymphoblastic Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-10-22

Completion:

2029-06-30

Conditions

• T-ALL

Interventions

• DRUG

No Results Yet

NCT06646289 | ACTIVE_NOT_RECRUITING | PHASE2

24 participants

A Follow-on Study for Second-Eye Treatment for Participants Previously Treated With Gene Therapy for X-Linked Retinitis Pigmentosa (XLRP)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-10-10

Completion:

2030-10-24

Conditions

• X-Linked Retinitis Pigmentosa

Interventions

• BIOLOGICAL
• OTHER

No Results Yet

NCT06642246 | RECRUITING | NA

10 participants

Sleep Promotion and Pediatric Hypertension

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2026-02-16

Completion:

2026-11-30

Conditions

• Insufficient Sleep
• Hypertension

Interventions

• BEHAVIORAL

No Results Yet

NCT06638892 | RECRUITING | NA

1000 participants

Using PrEP, Doing It for Ourselves

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2026-02-13

Completion:

2029-06-30

Conditions

• HIV Prevention
• PrEP

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT06637423 | RECRUITING | PHASE1/PHASE2

32 participants

A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Patients With Bladder Cancer (MK-2870-027)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-12-20

Completion:

2029-03-14

Conditions

• Non-Muscle Invasive Bladder Cancer

Interventions

• DRUG

No Results Yet