Clinical Trials Updated in 2026

NCT06712654 | RECRUITING | PHASE2

168 participants

A Study to Evaluate Safety, Tolerability and Efficacy of AP306 at Fixed Doses in Dialysis Participants With Hyperphosphatemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-26
Start Date:: 2026-06-01
Completion:: 2027-02-28

Conditions

Hyperphosphatemia
Chronic Kidney Disease Requiring Chronic Dialysis
End Stage Renal Disease on Dialysis

Interventions

DRUG

No Results Yet

NCT06711978 | COMPLETED | NA

66 participants

Comparison of the Efficacy and Safety of Mirogabalin and Duloxetine in Chemotherapy-induced Peripheral Neuropathy in a Randomized Controlled Trial: a Quality of Life Study in Cancer Survivors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-26
Start Date:: 2024-12-01
Completion:: 2026-04-15

Conditions

CIPN
CIPN - Chemotherapy-Induced Peripheral Neuropathy
CIPN in Adjuvant Breast Cancer Patients
Duloxetine
Mirogabalin

Interventions

DRUG

No Results Yet

NCT06708286 | COMPLETED | PHASE2/PHASE3

1820 participants

A Clinical Trials of Adsorbed Cell-free DPT Vaccine (Five-component)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-26
Start Date:: 2024-12-20
Completion:: 2025-07-01

Conditions

Diphtheria
Tetanus
Pertussis

Interventions

BIOLOGICAL

No Results Yet

NCT06705218 | ACTIVE_NOT_RECRUITING | NA

440 participants

Exploring Mindsets, Beliefs and Resilience Across the Cancer Experience

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-26
Start Date:: 2025-03-20
Completion:: 2027-04-30

Conditions

Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT06701812 | RECRUITING | PHASE2

23 participants

Digoxin Medulloblastoma Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-26
Start Date:: 2026-01-15
Completion:: 2027-02-28

Conditions

Medulloblastoma
Medulloblastoma, Non-WNT/Non-SHH

Interventions

DRUG

No Results Yet

NCT06681181 | ACTIVE_NOT_RECRUITING | PHASE1

48 participants

A First-time in Human (FTIH) Study to Evaluate Safety, Tolerability, Pharmacokinetics and Target Engagement of GSK4528287 in Healthy Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-26
Start Date:: 2024-11-18
Completion:: 2026-04-23

Conditions

Colitis, Ulcerative

Interventions

DRUG

No Results Yet

NCT06662162 | RECRUITING | NA

100 participants

Microcurrent Stimulation Therapy for Intermediate to Advanced Nonexudative Age-related Macular Degeneration

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-26
Start Date:: 2025-05-07
Completion:: 2027-03-31

Conditions

Age-Related Macular Degeneration
Age-related Macular Degeneration (ARMD)
Intermediate AMD
Geographic Atrophy Secondary to Age-related Macular Degeneration

Interventions

DEVICE

No Results Yet

NCT06661239 | COMPLETED | NA

60 participants

Effect of Benson Relaxation Technique on Pain Level, Insomnia, Nausea, Vomiting, and Retching in Oncology Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-26
Start Date:: 2024-11-01
Completion:: 2025-08-01

Conditions

Oncology Patients
Relaxation Program

Interventions

BEHAVIORAL

No Results Yet

NCT06661122 | RECRUITING

100 participants

A Study to Learn About How Safe Darolutamide is and How Well it Works in Combination With Androgen Deprivation Therapy and Docetaxel in Routine Medical Care for Japanese Men With Low Volume Metastatic Hormone-Sensitive Prostate Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-26
Start Date:: 2024-11-18
Completion:: 2031-03-31

Conditions

Metastatic Hormone-sensitive Prostate Cancer (mHSPC)
Low-volume Metastasis

Interventions

DRUG

No Results Yet

NCT06659445 | RECRUITING | PHASE2

324 participants

Study to Evaluate Efficacy and Safety of ONL1204 in Patients With GA Associated With AMD

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-26
Start Date:: 2025-10-28
Completion:: 2028-11-30

Conditions

Geographic Atrophy (GA)
Age - Related Macular Degeneration (AMD)

Interventions

DRUG
OTHER

No Results Yet

NCT06659341 | RECRUITING | PHASE1

104 participants

A Phase I Study of BAY3498264 Given Together With Sotorasib in Participants Who Have Advanced Solid Cancers With Specific Genetic Changes Called KRASG12C Mutation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-26
Start Date:: 2024-11-08
Completion:: 2027-04-26

Conditions

Advanced Solid Tumors Harboring KRAS G12C Mutation

Interventions

DRUG

No Results Yet

NCT06656936 | NOT_YET_RECRUITING | NA

1500 participants

The PharmFIT Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-26
Start Date:: 2026-09-01
Completion:: 2027-12-31

Conditions

Colorectal Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT06654869 | COMPLETED | NA

60 participants

Effects of Laughter Yoga on Symptom Severity, Hope, and Life Engagement in Patients Undergoing Chemotherapy; A Randomized Controlled Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-26
Start Date:: 2025-01-30
Completion:: 2025-06-30

Conditions

Cancer
Nurse's Role
Quality of Life

Interventions

BEHAVIORAL

No Results Yet

NCT06652334 | COMPLETED

40 participants

Comparison of Spinal Anesthesia and Erector Spinae Plane Block in Critically Adult Patients Undergoing Femur Surgery

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-26
Start Date:: 2024-03-20
Completion:: 2025-03-15

Conditions

Femoral Fractures

Interventions

PROCEDURE

No Results Yet

NCT06651567 | RECRUITING | PHASE2

320 participants

A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Agitation Associated With Alzheimer's Dementia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-26
Start Date:: 2024-10-22
Completion:: 2027-12-28

Conditions

Agitation Associated With Alzheimer's Dementia

Interventions

DRUG

No Results Yet

NCT06651073 | ACTIVE_NOT_RECRUITING

350 participants

ATTR-CM: A Multi-country, Non-interventional Disease Registry

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-26
Start Date:: 2024-10-01
Completion:: 2028-04-28

Conditions

Transthyretin Amyloid Cardiopathy

Interventions

OTHER

No Results Yet

NCT06649539 | ACTIVE_NOT_RECRUITING | PHASE4

40 participants

Delayed Dose Collagenase Clostridium Histolyticum (CCH) Protocol for Men With Peyronie's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-26
Start Date:: 2024-10-11
Completion:: 2029-10-31

Conditions

Peyronie Disease

Interventions

DRUG
DEVICE

No Results Yet

NCT06649201 | RECRUITING

40 participants

Vulvovaginal Graft-versus-Host Disease: Diagnosis and Microbiome Evaluation

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-26
Start Date:: 2024-12-19
Completion:: 2026-11-30

Conditions

Graft Vs Host Disease
Vulvovaginal Signs and Symptoms

Interventions

OTHER
DIAGNOSTIC_TEST

No Results Yet

NCT06636669 | ENROLLING_BY_INVITATION | PHASE4

152 participants

Probiotics in the Prevention of Recurrent Prosthetic Joint Infection of the Hip and Knee

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-26
Start Date:: 2025-08-15
Completion:: 2027-06-30

Conditions

Prosthetic-joint Infection
Dysbiosis

Interventions

DRUG
OTHER

No Results Yet

NCT06636383 | RECRUITING

140 participants

Glycogen Storage Disease Type Ia (GSDIa) Disease Monitoring Program

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-26
Start Date:: 2024-11-04
Completion:: 2036-12-31

Conditions

Glycogen Storage Disease Type Ia

Interventions

OTHER

No Results Yet

NCT06628570 | RECRUITING | NA

500 participants

Screening Strategies Among High-risk Populations for Anal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-26
Start Date:: 2024-12-16
Completion:: 2027-09-30

Conditions

Neoplasms
HPV-Related Anal Squamous Cell Carcinoma

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06619574 | RECRUITING | NA

80 participants

Temporomandibular Joint (TMJ) Positioning Accuracy and Efficiency Using a Dental Compass.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-26
Start Date:: 2024-11-08
Completion:: 2027-06-01

Conditions

Temporomandibular Joint Syndrome

Interventions

DEVICE
OTHER

No Results Yet

NCT06618417 | RECRUITING | NA

936 participants

Evaluating the Impact of Home-Based Sleep Apnea Diagnostic on Well-Being, Health Behavior, and AF Load in Patients With Atrial Fibrillation Using a Decentralized Platform

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-26
Start Date:: 2024-12-05
Completion:: 2027-02-01

Conditions

Atrial Fibrillation (AF)
Sleep Apnea

Interventions

DEVICE

No Results Yet

NCT06607939 | RECRUITING | PHASE1

36 participants

ORB-021 In Patients With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-26
Start Date:: 2024-11-21
Completion:: 2027-01-29

Conditions

Advanced Solid Tumors Cancer

Interventions

DRUG

No Results Yet

NCT06607055 | RECRUITING

40 participants

Immunity Markers in Intensive Care Patients and Ventilator-associated Pneumonia

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-26
Start Date:: 2023-10-04
Completion:: 2026-12-31

Conditions

Pneumonia, Ventilator-Associated

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06605469 | RECRUITING

500 participants

Ejaculatory and Orgasmic Dysfunction Registry

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-26
Start Date:: 2024-05-30
Completion:: 2029-05-31

Conditions

Ejaculatory Dysfunction
Premature Ejaculation
Delayed Ejaculation
Anorgasmia
Anejaculation
Dysejaculation
Dysorgasmia

No Results Yet

NCT06600165 | RECRUITING

1000 participants

Intraoperative Confocal Laser Scanning Microscopy With Use of AI for Optimized Surgical Excision of Basal Cell Carcinoma

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-26
Start Date:: 2025-03-01
Completion:: 2026-12-31

Conditions

Basal Cell Carcinoma

Interventions

PROCEDURE

No Results Yet

NCT06598137 | ACTIVE_NOT_RECRUITING

645 participants

Study to Examine Lesions of the Skin Using Confocal Laser Microscopy

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-26
Start Date:: 2024-02-01
Completion:: 2027-12-31

Conditions

Benign Skin Tumor
Basal Cell Carcinoma
Melanoma
Squamous Cell Cancer

Interventions

PROCEDURE

No Results Yet

NCT06597149 | RECRUITING | NA

30 participants

Effect of Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) on Plasma Insulin Levels

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-26
Start Date:: 2025-04-16
Completion:: 2027-05-31

Conditions

Healthy

Interventions

DEVICE

No Results Yet

NCT06591741 | NOT_YET_RECRUITING | NA

100 participants

PCA Administration in Prosthetic Joint Infection

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-26
Start Date:: 2027-01-31
Completion:: 2028-07-31

Conditions

Prosthetic Joint Infection

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06590181 | COMPLETED | NA

60 participants

Comparing the Effects of Yoga Nidra to Yoga Nidra With Pain Acceptance Intention and Motor Imagery on Pain Outcomes

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-26
Start Date:: 2024-09-12
Completion:: 2025-07-29

Conditions

Chronic Pain

Interventions

OTHER

No Results Yet

NCT06585787 | RECRUITING | PHASE3

406 participants

A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-26
Start Date:: 2024-09-26
Completion:: 2026-11-24

Conditions

Alzheimer Disease

Interventions

DRUG

No Results Yet

NCT06584201 | COMPLETED | NA

70 participants

Effects of Erector Spinae Plane Block and Paravertebral Block on Early Postoperative Pulmonary Function Test Parameters

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-26
Start Date:: 2024-11-01
Completion:: 2025-09-30

Conditions

Respiratory Function Loss
Pain, Postoperative
Opioid Use

Interventions

PROCEDURE

No Results Yet

NCT06577987 | ACTIVE_NOT_RECRUITING | PHASE1

220 participants

Safety/Efficacy Study of CID-078 in Patients With Advanced Solid Tumor Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-26
Start Date:: 2024-08-14
Completion:: 2027-01-14

Conditions

Advanced Solid Tumor
Metastatic Solid Tumor
Refractory Solid Tumor
Cancer
Lung Cancer
Triple Negative Breast Cancer
Breast Neoplasms
Neuroendocrine Tumors
Neuroendocrine Carcinoma
RB1 Gene Mutation

Interventions

DRUG

No Results Yet

NCT06565455 | ACTIVE_NOT_RECRUITING | NA

64 participants

Growing Healthy Children and Families in Rural Arkansas

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-26
Start Date:: 2026-02-02
Completion:: 2026-05-31

Conditions

Pediatric Obesity
Health Behavior, Risky

Interventions

BEHAVIORAL

No Results Yet

NCT06557512 | RECRUITING | NA

23 participants

Adjuvant Hypofractionated Stereotactic Radiosurgery for Intermediate-risk Meningioma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-26
Start Date:: 2024-12-13
Completion:: 2029-09-30

Conditions

Meningioma
Meningioma, Malignant
Recurrent Meningioma

Interventions

RADIATION
PROCEDURE

No Results Yet

NCT06554886 | ACTIVE_NOT_RECRUITING | NA

12 participants

A Study Investigating Peripheral Cryoneurolysis in Adults With Chronic Migraine

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-26
Start Date:: 2024-08-29
Completion:: 2025-05-28

Conditions

Chronic Migraine

Interventions

DEVICE

No Results Yet

NCT06533969 | RECRUITING | NA

3 participants

Assessment of Neural Signals for the Control of Assistive Devices

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-26
Start Date:: 2024-09-06
Completion:: 2027-12-31

Conditions

Spinal Cord Injury (SCI), Initial Encounter

Interventions

PROCEDURE
DEVICE

No Results Yet

NCT06533826 | RECRUITING | PHASE2

357 participants

TReatment of ADC-Refractory Breast CancEr With Dato-DXd or T-DXd: TRADE DXd

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-26
Start Date:: 2024-10-29
Completion:: 2028-01-01

Conditions

Breast Cancer
HER2-low Breast Cancer
Metastatic Breast Cancer
HER2-negative Breast Cancer

Interventions

DRUG

No Results Yet

NCT06513936 | COMPLETED | NA

120 participants

Nursing Interventions on Prevention Medical Device Related Pressure Injury (MDRPI)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-26
Start Date:: 2024-10-01
Completion:: 2025-12-01

Conditions

Medical Device Site Erosion

Interventions

PROCEDURE

No Results Yet