Clinical Trials

NCT04663308 | ACTIVE_NOT_RECRUITING | PHASE2

182 participants

A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Sclerosing Cholangitis (PSC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2020-12-18

Completion:

2026-02-20

Conditions

• Primary Sclerosing Cholangitis

Interventions

• DRUG

No Results Yet

NCT04656652 | ACTIVE_NOT_RECRUITING | PHASE3

605 participants

Study of DS-1062a Versus Docetaxel in Previously Treated Advanced or Metastatic Non-small Cell Lung Cancer With or Without Actionable Genomic Alterations (TROPION-LUNG01)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2020-12-21

Completion:

2024-05-10

Conditions

• Non-small Cell Lung Cancer

Interventions

• DRUG

Results Available

NCT04654468 | ACTIVE_NOT_RECRUITING | PHASE3

51 participants

A Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Not Previously Treated With Complement Inhibition

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2021-03-17

Completion:

2022-02-10

Conditions

• Paroxysmal Nocturnal Hemoglobinuria

Interventions

• DRUG

Results Available

NCT04648969 | COMPLETED | PHASE2

18 participants

Prolonged Pulsatile Kisspeptin Administration in Hypogonadotropic Hypogonadism

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2019-05-03

Completion:

2025-08-31

Conditions

• Hypogonadotropic Hypogonadism

Interventions

• DRUG

Results Available

NCT04647253 | ACTIVE_NOT_RECRUITING | PHASE3

600 participants

A Clinical Trial to Assess the Agent Paclitaxel Coated PTCA Balloon Catheter for the Treatment of Subjects With In-Stent Restenosis (ISR)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2021-05-11

Completion:

2023-10-02

Conditions

• In-Stent Restenosis

Interventions

• DEVICE

Results Available

NCT04647240 | RECRUITING | PHASE2

80 participants

MTX-001 for the Treatment of Non-Healing Venous Stasis Ulcers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2022-02-26

Completion:

2027-03-31

Conditions

• Venous Stasis Ulcer
• Venous Leg Ulcer

Interventions

• BIOLOGICAL

No Results Yet

NCT04631601 | TERMINATED | PHASE1/PHASE2

55 participants

Safety and Efficacy of Therapies for Metastatic Castration-resistant Prostate Cancer (mCRPC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2021-01-15

Completion:

2023-10-23

Conditions

• Metastatic Castration-resistant Prostate Cancer

Interventions

• DRUG

Results Available

NCT04605081 | COMPLETED | PHASE2/PHASE3

24 participants

Pharmacological and Behavioral Treatments After Bariatric Surgery: Maintenance Treatment (Stage 2a)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2022-06-10

Completion:

2026-06-04

Conditions

• Loss-of-Control Eating
• Obesity/Overweight

Interventions

• DRUG
• OTHER

Results Available

NCT04599478 | COMPLETED | PHASE2/PHASE3

92 participants

Pharmacological and Behavioral Treatment After Bariatric Surgery: Acute (Stage 1)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2021-06-29

Completion:

2026-06-04

Conditions

• Loss-of-control Eating
• Obesity/Overweight

Interventions

• DRUG
• BEHAVIORAL
• OTHER

Results Available

NCT04584814 | COMPLETED | NA

10 participants

Analyze Changes in Respiratory Rate When Using the Scare Respirator

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2020-03-01

Completion:

2021-10-31

Conditions

• Apnea of Newborn
• Preterm Labor

Interventions

• DEVICE

No Results Yet

NCT04579107 | COMPLETED | NA

300 participants

KARMA Kontrast Evaluating Contrast Enhanced Mammography in Early Detection of Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2021-10-01

Completion:

2024-08-31

Conditions

• Breast Cancer

Interventions

• COMBINATION_PRODUCT

No Results Yet

NCT04544293 | ACTIVE_NOT_RECRUITING | PHASE3

164 participants

Clinical Trial of Inhaled Molgramostim Nebulizer Solution in Autoimmune Pulmonary Alveolar Proteinosis (aPAP)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2021-05-19

Completion:

2023-11-30

Conditions

• Autoimmune Pulmonary Alveolar Proteinosis

Interventions

• DRUG

Results Available

NCT04518228 | TERMINATED

205 participants

Pharmacokinetic Properties of Antiretroviral and Anti-Tuberculosis Drugs During Pregnancy and Postpartum

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-26

Start Date:

2021-09-01

Completion:

2025-04-24

Conditions

• HIV
• Tuberculosis

Interventions

• DRUG

Results Available

NCT04504955 | RECRUITING

10000 participants

CorEvitas Atopic Dermatitis Registry: A Study of Post Approval Drug Safety and Effectiveness

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-26

Start Date:

2020-07-14

Completion:

2100-12-31

Conditions

• Atopic Dermatitis

Interventions

• OTHER

No Results Yet

NCT04458532 | RECRUITING | NA

152 participants

Exercise Therapy to Improve Cardiovascular Health in Post-Menopausal Women After Treatment for Early Stage Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2020-10-08

Completion:

2027-03-31

Conditions

• Early Stage Breast Cancer

Interventions

• OTHER

No Results Yet

NCT04456322 | ACTIVE_NOT_RECRUITING | PHASE3

381 participants

Radiotherapy Plus Nimotuzumab or Cisplatin in Nasopharyngeal Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2020-08-17

Completion:

2024-05-11

Conditions

• Nasopharyngeal Carcinoma

Interventions

• DRUG

No Results Yet

NCT04452149 | COMPLETED | NA

826 participants

Algorithm Using LINQ Sensors for Evaluation And Treatment of Heart Failure

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2020-09-03

Completion:

2025-06-02

Conditions

• Heart Failure NYHA Class II
• Heart Failure NYHA Class III

Interventions

• DEVICE
• OTHER

Results Available

NCT04437511 | ACTIVE_NOT_RECRUITING | PHASE3

1736 participants

A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2020-06-19

Completion:

2023-04-14

Conditions

• Alzheimer Disease

Interventions

• DRUG

Results Available

NCT04433221 | NOT_YET_RECRUITING | PHASE1/PHASE2

20 participants

Combination Immunotherapy Targeting Sarcomas

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2027-07-01

Completion:

2029-05-31

Conditions

• Sarcoma
• Osteoid Sarcoma
• Ewing Sarcoma

Interventions

• BIOLOGICAL

No Results Yet

NCT04432649 | NOT_YET_RECRUITING | PHASE1/PHASE2

100 participants

Targeting CD276 (B7-H3) Positive Solid Tumors by 4SCAR-276

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2027-06-01

Completion:

2029-12-31

Conditions

• Solid Tumor

Interventions

• BIOLOGICAL

No Results Yet

NCT04430595 | NOT_YET_RECRUITING | PHASE1/PHASE2

100 participants

Multi-4SCAR-T Therapy Targeting Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2027-06-01

Completion:

2029-12-31

Conditions

• Breast Cancer

Interventions

• BIOLOGICAL

No Results Yet

NCT04429451 | NOT_YET_RECRUITING | PHASE1/PHASE2

100 participants

PSMA-specific CAR-T Cell Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2026-12-31

Completion:

2029-12-31

Conditions

• PSMA Positive Tumors or Tumor Tissues

Interventions

• BIOLOGICAL

No Results Yet

NCT04429438 | NOT_YET_RECRUITING | PHASE1/PHASE2

11 participants

Multi-CAR-T Cells Targeting B Cell Lymphomas

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2027-06-01

Completion:

2029-12-31

Conditions

• B Cell Lymphoma (BCL)

Interventions

• BIOLOGICAL

No Results Yet

NCT04387552 | COMPLETED | NA

2093 participants

Social Media and Risk Reduction Teaching-Enhanced Reach

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2022-01-20

Completion:

2025-06-07

Conditions

• Breastfeeding
• SUID
• SIDS

Interventions

• BEHAVIORAL

Results Available

NCT04340596 | ACTIVE_NOT_RECRUITING | PHASE1

118 participants

Safety, Tolerability, and Efficacy of IL-15 Superagonist (N-803) With and Without Combination Broadly Neutralizing Antibodies to Induce HIV-1 Control During Analytic Treatment Interruption

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2021-05-21

Completion:

2026-05-07

Conditions

• HIV Infection

Interventions

• BIOLOGICAL

No Results Yet

NCT04333745 | ACTIVE_NOT_RECRUITING | NA

22 participants

Influence of Obesity on Oxalate Metabolism and Handling in Calcium Oxalate Stone Formers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2021-09-01

Completion:

2026-12-01

Conditions

• Kidney Stone

Interventions

• OTHER
• DIETARY_SUPPLEMENT

No Results Yet

NCT04329494 | RECRUITING | PHASE1

49 participants

PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2020-08-21

Completion:

2028-01-05

Conditions

• Clinical Stage IV Gastric Cancer AJCC v8
• Clinical Stage IVA Gastric Cancer AJCC v8
• Clinical Stage IVB Gastric Cancer AJCC v8
• Malignant Uterine Neoplasm
• Metastatic Appendix Carcinoma
• Metastatic Colorectal Carcinoma
• Metastatic Gastric Carcinoma
• Metastatic Malignant Neoplasm in the Peritoneum
• Metastatic Malignant Solid Neoplasm
• Metastatic Ovarian Carcinoma
• Pathologic Stage IV Gastric Cancer AJCC v8
• Peritoneal Carcinomatosis
• Postneoadjuvant Therapy Stage IV Gastric Cancer AJCC v8
• Stage IV Appendix Carcinoma AJCC v8
• Stage IV Colorectal Cancer AJCC v8
• Stage IV Ovarian Cancer AJCC v8
• Stage IV Uterine Corpus Cancer AJCC v8
• Stage IVA Appendix Carcinoma AJCC v8
• Stage IVA Colorectal Cancer AJCC v8
• Stage IVA Ovarian Cancer AJCC v8
• Stage IVA Uterine Corpus Cancer AJCC v8
• Stage IVB Appendix Carcinoma AJCC v8
• Stage IVB Colorectal Cancer AJCC v8
• Stage IVB Ovarian Cancer AJCC v8
• Stage IVB Uterine Corpus Cancer AJCC v8
• Stage IVC Appendix Carcinoma AJCC v8
• Stage IVC Colorectal Cancer AJCC v8

Interventions

• PROCEDURE
• DRUG
• DEVICE
• OTHER

No Results Yet

NCT04297956 | COMPLETED

36 participants

Survey on Patients After Childbearth Following Bariatric Surgery

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-26

Start Date:

2020-02-05

Completion:

2023-02-15

Conditions

• Bariatric Surgery Status in Childbirth
• Puerperal Depression

No Results Yet

NCT04288726 | ACTIVE_NOT_RECRUITING | PHASE1

27 participants

Allogeneic CD30.CAR-EBVSTs in Patients With Relapsed or Refractory CD30-Positive Lymphomas

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2020-09-16

Completion:

2027-06-01

Conditions

• Extranodal Natural Killer/T-Cell Lymphoma, Nasal Type
• Classical Hodgkin Lymphoma

Interventions

• BIOLOGICAL

No Results Yet

NCT04261738 | TERMINATED | NA

6 participants

Effects of HBO on Glucose in Patients With DM

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2022-09-02

Completion:

2025-09-04

Conditions

• Diabetes Mellitus, Type 2
• Diabetes Mellitus, Type 1

Interventions

• DEVICE

No Results Yet

NCT04214288 | ACTIVE_NOT_RECRUITING | PHASE2

240 participants

A Study to Investigate Efficacy and Safety With Oral AZD9833 Compared With Intramuscular Fulvestrant in Post-menopausal Women at Least 18 Years of Age With Advanced ER-positive HER2 Negative Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2020-04-22

Completion:

2022-08-30

Conditions

• Advanced ER-Positive HER2-Negative Breast Cancer

Interventions

• DRUG

Results Available

NCT04212923 | COMPLETED | NA

20 participants

eHealth Based Self-management Intervention for Chronic Kidney Disease Care in China

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2024-10-09

Completion:

2026-06-30

Conditions

• Chronic Kidney Diseases

Interventions

• BEHAVIORAL

No Results Yet

NCT04209595 | COMPLETED | PHASE1/PHASE2

10 participants

PLX038 (PEGylated SN38) and Rucaparib in Solid Tumors and Small Cell Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2020-04-08

Completion:

2021-08-13

Conditions

• Small Cell Lung Cancer
• Extra-Pulmonary Small Cell Carcinomas

Interventions

• DRUG

Results Available

NCT04157127 | RECRUITING | PHASE1

18 participants

Th-1 Dendritic Cell Immunotherapy Plus Standard Chemotherapy for Pancreatic Adenocarcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2020-08-03

Completion:

2026-12-31

Conditions

• Pancreatic Adenocarcinoma
• Pancreatic Cancer
• Pancreatic Adenosquamous Carcinoma

Interventions

• BIOLOGICAL

No Results Yet

NCT04145141 | COMPLETED

132 participants

National Translational Science Network of Precision-based Immunotherapy for Primary Liver Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-26

Start Date:

2021-07-28

Completion:

2026-08-06

Conditions

• Hepatocellular Carcinoma
• Liver Cancer
• Cholangiocarcinoma

No Results Yet

NCT04090528 | ACTIVE_NOT_RECRUITING | PHASE2

60 participants

pTVG-HP DNA Vaccine With or Without pTVG-AR DNA Vaccine and Pembrolizumab in Patients With Castration-Resistant, Metastatic Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2019-10-21

Completion:

2024-11-24

Conditions

• Castration-resistant Prostate Cancer
• Metastatic Cancer
• Prostate Cancer

Interventions

• BIOLOGICAL
• DRUG

Results Available

NCT04082533 | ACTIVE_NOT_RECRUITING | PHASE4

65 participants

Intravenous (IV) Hydrocortisone for TKA (Total Knee Arthroplasty)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2019-07-24

Completion:

2027-07-31

Conditions

• Pain
• Arthrofibrosis
• Osteoarthritis, Knee

Interventions

• DRUG

No Results Yet

NCT04078334 | RECRUITING | NA

400 participants

Personalized Exercises Program Prescription to Prevent Functional Decline Throughout Older Adults Hospitalization

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2020-10-02

Completion:

2026-12-31

Conditions

• Aging
• Hospitalization

Interventions

• OTHER

No Results Yet

NCT04075162 | RECRUITING

77000 participants

Community Benefit of No-charge Calcium Score Screening Program

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-26

Start Date:

2014-01-31

Completion:

2030-12-31

Conditions

• Cardiovascular Risk Factor

No Results Yet

NCT04055207 | COMPLETED | NA

306 participants

VA Video Connect in HIV Care

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2021-07-01

Completion:

2024-10-31

Conditions

• HIV

Interventions

• OTHER

Results Available