Clinical Trials

NCT04297956 | COMPLETED

36 participants

Survey on Patients After Childbearth Following Bariatric Surgery

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-26

Start Date:

2020-02-05

Completion:

2023-02-15

Conditions

• Bariatric Surgery Status in Childbirth
• Puerperal Depression

No Results Yet

NCT04288726 | ACTIVE_NOT_RECRUITING | PHASE1

27 participants

Allogeneic CD30.CAR-EBVSTs in Patients With Relapsed or Refractory CD30-Positive Lymphomas

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2020-09-16

Completion:

2027-06-01

Conditions

• Extranodal Natural Killer/T-Cell Lymphoma, Nasal Type
• Classical Hodgkin Lymphoma

Interventions

• BIOLOGICAL

No Results Yet

NCT04261738 | TERMINATED | NA

6 participants

Effects of HBO on Glucose in Patients With DM

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2022-09-02

Completion:

2025-09-04

Conditions

• Diabetes Mellitus, Type 2
• Diabetes Mellitus, Type 1

Interventions

• DEVICE

No Results Yet

NCT04214288 | ACTIVE_NOT_RECRUITING | PHASE2

240 participants

A Study to Investigate Efficacy and Safety With Oral AZD9833 Compared With Intramuscular Fulvestrant in Post-menopausal Women at Least 18 Years of Age With Advanced ER-positive HER2 Negative Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2020-04-22

Completion:

2022-08-30

Conditions

• Advanced ER-Positive HER2-Negative Breast Cancer

Interventions

• DRUG

Results Available

NCT04212923 | COMPLETED | NA

20 participants

eHealth Based Self-management Intervention for Chronic Kidney Disease Care in China

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2024-10-09

Completion:

2026-06-30

Conditions

• Chronic Kidney Diseases

Interventions

• BEHAVIORAL

No Results Yet

NCT04209595 | COMPLETED | PHASE1/PHASE2

10 participants

PLX038 (PEGylated SN38) and Rucaparib in Solid Tumors and Small Cell Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2020-04-08

Completion:

2021-08-13

Conditions

• Small Cell Lung Cancer
• Extra-Pulmonary Small Cell Carcinomas

Interventions

• DRUG

Results Available

NCT04157127 | RECRUITING | PHASE1

18 participants

Th-1 Dendritic Cell Immunotherapy Plus Standard Chemotherapy for Pancreatic Adenocarcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2020-08-03

Completion:

2026-12-31

Conditions

• Pancreatic Adenocarcinoma
• Pancreatic Cancer
• Pancreatic Adenosquamous Carcinoma

Interventions

• BIOLOGICAL

No Results Yet

NCT04145141 | COMPLETED

132 participants

National Translational Science Network of Precision-based Immunotherapy for Primary Liver Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-26

Start Date:

2021-07-28

Completion:

2026-08-06

Conditions

• Hepatocellular Carcinoma
• Liver Cancer
• Cholangiocarcinoma

No Results Yet

NCT04090528 | ACTIVE_NOT_RECRUITING | PHASE2

60 participants

pTVG-HP DNA Vaccine With or Without pTVG-AR DNA Vaccine and Pembrolizumab in Patients With Castration-Resistant, Metastatic Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2019-10-21

Completion:

2024-11-24

Conditions

• Castration-resistant Prostate Cancer
• Metastatic Cancer
• Prostate Cancer

Interventions

• BIOLOGICAL
• DRUG

Results Available

NCT04082533 | ACTIVE_NOT_RECRUITING | PHASE4

65 participants

Intravenous (IV) Hydrocortisone for TKA (Total Knee Arthroplasty)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2019-07-24

Completion:

2027-07-31

Conditions

• Pain
• Arthrofibrosis
• Osteoarthritis, Knee

Interventions

• DRUG

No Results Yet

NCT04078334 | RECRUITING | NA

400 participants

Personalized Exercises Program Prescription to Prevent Functional Decline Throughout Older Adults Hospitalization

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2020-10-02

Completion:

2026-12-31

Conditions

• Aging
• Hospitalization

Interventions

• OTHER

No Results Yet

NCT04075162 | RECRUITING

77000 participants

Community Benefit of No-charge Calcium Score Screening Program

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-26

Start Date:

2014-01-31

Completion:

2030-12-31

Conditions

• Cardiovascular Risk Factor

No Results Yet

NCT04055207 | COMPLETED | NA

306 participants

VA Video Connect in HIV Care

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2021-07-01

Completion:

2024-10-31

Conditions

• HIV

Interventions

• OTHER

Results Available

NCT04044768 | ACTIVE_NOT_RECRUITING | PHASE2

52 participants

Spearhead 1 Study in Subjects With Advanced Synovial Sarcoma or Myxoid/Round Cell Liposarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2019-08-13

Completion:

2021-08-29

Conditions

• Synovial Sarcoma
• Myxoid Liposarcoma

Interventions

• GENETIC

Results Available

NCT04034927 | ACTIVE_NOT_RECRUITING | PHASE2

61 participants

Testing the Addition of an Immunotherapy Drug, Tremelimumab, to the PARP Inhibition Drug, Olaparib, for Recurrent Ovarian, Fallopian Tube or Peritoneal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2019-12-04

Completion:

2021-07-31

Conditions

• Fallopian Tube Endometrioid Tumor
• Fallopian Tube High Grade Serous Adenocarcinoma
• Malignant Ovarian Endometrioid Tumor
• Ovarian High Grade Serous Adenocarcinoma
• Platinum-Sensitive Fallopian Tube Carcinoma
• Platinum-Sensitive Ovarian Carcinoma
• Platinum-Sensitive Primary Peritoneal Carcinoma
• Primary Peritoneal High Grade Serous Adenocarcinoma
• Recurrent Fallopian Tube Carcinoma
• Recurrent Fallopian Tube Endometrioid Adenocarcinoma
• Recurrent Ovarian Endometrioid Adenocarcinoma
• Recurrent Ovarian Serous Adenocarcinoma
• Recurrent Primary Peritoneal Carcinoma
• Recurrent Primary Peritoneal Endometrioid Adenocarcinoma

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL

Results Available

NCT04033302 | NOT_YET_RECRUITING | PHASE1/PHASE2

30 participants

Multi-CAR T Cell Therapy Targeting CD7-positive Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2026-12-31

Completion:

2029-12-31

Conditions

• T-cell Acute Lymphoblastic Leukemia
• T-cell Acute Lymphoblastic Lymphoma
• Acute Myeloid Leukemia
• NK Cell Lymphoma

Interventions

• BIOLOGICAL

No Results Yet

NCT04025879 | ACTIVE_NOT_RECRUITING | PHASE3

461 participants

A Study of Neoadjuvant Chemotherapy Plus Nivolumab Versus Neoadjuvant Chemotherapy Plus Placebo, Followed by Surgical Removal and Adjuvant Treatment With Nivolumab or Placebo for Participants With Surgically Removable Early Stage Non-small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2019-11-05

Completion:

2023-07-26

Conditions

• Carcinoma, Non-Small-Cell Lung

Interventions

• BIOLOGICAL
• DRUG

Results Available

NCT04019860 | COMPLETED | NA

131 participants

Time-restricted Eating and High Intensity Interval Training Among Women

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2019-08-12

Completion:

2021-03-16

Conditions

• Obesity; Endocrine

Interventions

• BEHAVIORAL

No Results Yet

NCT04016129 | NOT_YET_RECRUITING | PHASE1/PHASE2

100 participants

CAR-T Immunotherapy Targeting CD19- ALL

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2027-07-01

Completion:

2028-06-30

Conditions

• B-cell Leukemia

Interventions

• BIOLOGICAL

No Results Yet

NCT03995082 | ACTIVE_NOT_RECRUITING | NA

925 participants

Breast Cancer Patient Engagement With Patient Reported Outcome Measure Survey

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2019-10-30

Completion:

2028-12-31

Conditions

• Breast Cancer
• Patient Reported Outcomes

Interventions

• OTHER

No Results Yet

NCT03968445 | COMPLETED | PHASE1

6 participants

Neuroinflammation After Myocardial Infarction - Imaging Substudy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2019-10-17

Completion:

2026-08-17

Conditions

• Myocardial Infarction

Interventions

• DRUG

No Results Yet

NCT03961243 | NOT_YET_RECRUITING | PHASE1

10 participants

Lentiviral FIX Gene Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2027-06-01

Completion:

2028-05-31

Conditions

• Hemophilia B

Interventions

• BIOLOGICAL

No Results Yet

NCT03914768 | NOT_YET_RECRUITING | PHASE1

10 participants

Immune Modulatory DC Vaccine Against Brain Tumor

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2026-12-31

Completion:

2029-05-31

Conditions

• Diffuse Intrinsic Pontine Glioma or Glioblastoma

Interventions

• BIOLOGICAL

No Results Yet

NCT03876223 | RECRUITING

180 participants

Women's Ischemia Syndrome Evaluation (WISE) Pre-HFpEF

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-26

Start Date:

2019-07-24

Completion:

2027-02-28

Conditions

• Coronary Microvascular Dysfunction
• Heart Failure With Preserved Ejection Fraction (HFpEF)

No Results Yet

NCT03875235 | ACTIVE_NOT_RECRUITING | PHASE3

810 participants

Durvalumab or Placebo in Combination With Gemcitabine/Cisplatin in Patients With 1st Line Advanced Biliary Tract Cancer (TOPAZ-1)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2019-04-16

Completion:

2021-08-11

Conditions

• Biliary Tract Neoplasms

Interventions

• DRUG

Results Available

NCT03870672 | ACTIVE_NOT_RECRUITING | NA

72 participants

rTMS Plus CCFES-mediated Functional Task Practice for Severe Stroke

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2019-05-14

Completion:

2026-07-23

Conditions

• Stroke
• Hemiplegia
• Cerebrovascular Accident (CVA)
• Hemiparesis

Interventions

• DEVICE

No Results Yet

NCT03853772 | ENROLLING_BY_INVITATION

2000 participants

The Johns Hopkins Heartburn Center Registry

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-26

Start Date:

2019-04-27

Completion:

2027-12-31

Conditions

• Gastroesophageal Reflux Disease
• Barrett Esophagus
• Laryngopharyngeal Reflux
• Esophagitis

No Results Yet

NCT03850925 | COMPLETED | NA

25 participants

Comparison of Picosecond Pulsed Nd:YAG Laser and Fractional Laser for the Treatment of Acne Scars

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2019-05-01

Completion:

2020-04-22

Conditions

• Acne Scars

Interventions

• PROCEDURE

No Results Yet

NCT03835767 | RECRUITING | PHASE2

200 participants

Food-Specific and Component IgE Threshold Levels That Predict Food Allergy in People With Elevated Total Serum IgE Levels and Atopic Dermatitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2019-04-19

Completion:

2027-12-31

Conditions

• Milk and/or Peanut Allergy

Interventions

• OTHER

No Results Yet

NCT03830229 | RECRUITING

1000 participants

Long Term Follow-Up of Patients With Mesothelioma and Individuals With Germline Mutations in BAP1

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-26

Start Date:

2019-03-13

Completion:

2032-12-31

Conditions

• Mesothelioma
• Families

No Results Yet

NCT03799562 | COMPLETED | PHASE2

97 participants

Neurosteroids for Treatment of PTSD in Veterans

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2019-06-27

Completion:

2025-07-14

Conditions

• Posttraumatic Stress Disorder

Interventions

• DRUG

Results Available

NCT03672864 | COMPLETED | NA

18 participants

Parent Therapist Partnership to Provide Early, Intensive Exercise in Perinatal Stroke

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2019-02-15

Completion:

2026-04-22

Conditions

• Perinatal Stroke

Interventions

• BEHAVIORAL

No Results Yet

NCT03654066 | COMPLETED | PHASE4

9 participants

Botox or Botox With Esophageal Dilation in Patients With Achalasia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2019-05-13

Completion:

2026-06-01

Conditions

• Achalasia

Interventions

• DRUG
• DEVICE
• OTHER
• DIAGNOSTIC_TEST

No Results Yet

NCT03645486 | NOT_YET_RECRUITING | NA

10 participants

Lentiviral Gene Therapy for CGD

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2027-07-01

Completion:

2028-06-30

Conditions

• Chronic Granulomatous Disease

Interventions

• GENETIC

No Results Yet

NCT03645460 | NOT_YET_RECRUITING | NA

10 participants

Gene Therapy for ADA-SCID Using an Improved Lentiviral Vector (Ivlv-ADA)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2027-06-30

Completion:

2028-07-31

Conditions

• Adenosine DeAminase Severe Combined ImmunoDeficiency (ADA-SCID)

Interventions

• GENETIC

No Results Yet

NCT03644186 | COMPLETED | PHASE2

147 participants

To Reduce the Use of Chemotherapy in Postmenopausal Patients With ER-positive and HER2-positive Breast Cancer (TOUCH)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2019-04-16

Completion:

2023-01-03

Conditions

• Breast Cancer
• Estrogen Receptor Positive Tumor
• HER2-positive Breast Cancer

Interventions

• DRUG

Results Available

NCT03632239 | ENROLLING_BY_INVITATION

1000 participants

Reverse Phenotyping Core

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-26

Start Date:

2020-01-23

Completion:

2028-06-01

Conditions

• Harboring of Unexpected Genetic Variant

No Results Yet

NCT03615326 | COMPLETED | PHASE3

738 participants

Pembrolizumab/Placebo Plus Trastuzumab Plus Chemotherapy in Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Advanced Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (MK-3475-811/KEYNOTE-811)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2018-10-05

Completion:

2024-03-20

Conditions

• Gastric Neoplasms
• Gastroesophageal Junction Adenocarcinoma

Interventions

• BIOLOGICAL
• DRUG

Results Available

NCT03614650 | NOT_YET_RECRUITING | PHASE1/PHASE2

100 participants

Immunotherapy Treating GI Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2027-06-01

Completion:

2028-06-30

Conditions

• Cancer

Interventions

• BIOLOGICAL

No Results Yet

NCT03573089 | RECRUITING | NA

3600 participants

Pragmatic Randomised Trial of High Or Standard PHosphAte Targets in End-stage Kidney Disease (PHOSPHATE)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2019-12-10

Completion:

2027-12-31

Conditions

• Kidney Failure, Chronic
• Hyperphosphatemia

Interventions

• DRUG

No Results Yet