Clinical Trials

NCT05460767 | ACTIVE_NOT_RECRUITING | PHASE1

504 participants

Safety, Tolerability and Preliminary Efficacy of IBI363 in Subjects With Advanced Solid Tumors or Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2022-08-31

Completion:

2026-12-31

Conditions

• Solid Tumors or Lymphoma

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT05404594 | ACTIVE_NOT_RECRUITING | NA

80 participants

Multimodal Approach to the Ontogenesis of Nociception in Very Preterm and Term Infants

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2019-07-17

Completion:

2026-12-31

Conditions

• Procedural Pain
• Pre-Term
• Venipuncture

Interventions

• BEHAVIORAL

No Results Yet

NCT05389423 | RECRUITING | PHASE1

25 participants

Pomalidomide and Dose-Adjusted EPOCH +/- Rituximab for HIV-Associated Lymphomas

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2023-06-27

Completion:

2028-06-01

Conditions

• Diffuse Large Cell Lymphoma
• Non-Hodgkin Lymphoma
• Burkitt Lymphoma
• Plasmablastic Lymphoma
• B-Cell Neoplasm

Interventions

• DRUG

No Results Yet

NCT05382338 | RECRUITING | PHASE3

225 participants

A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2023-02-20

Completion:

2029-12-31

Conditions

• Childhood Medulloblastoma

Interventions

• PROCEDURE
• DRUG
• OTHER
• RADIATION

No Results Yet

NCT05373264 | RECRUITING | PHASE3

300 participants

HYDROchlorothiazide to PROTECT Polycystic Kidney Disease Patients and Improve Their Quality of Life

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2024-07-31

Completion:

2030-07-31

Conditions

• ADPKD

Interventions

• DRUG

No Results Yet

NCT05353647 | ACTIVE_NOT_RECRUITING | PHASE2

25 participants

A Gene Transfer Study Inducing Fetal Hemoglobin in Sickle Cell Disease (GRASP, BMT CTN 2001)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2022-07-12

Completion:

2027-10-31

Conditions

• Sickle Cell Disease

Interventions

• BIOLOGICAL

No Results Yet

NCT05348356 | COMPLETED | PHASE2

53 participants

Nirogacestat in Ovarian Granulosa Cell Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2022-08-30

Completion:

2025-07-08

Conditions

• Ovarian Granulosa-Stromal Tumor
• Ovarian Granulosa Cell Tumor
• Ovarian Cancer

Interventions

• DRUG

Results Available

NCT05338242 | COMPLETED | NA

30 participants

Monitoring Environmental Exposures and Behavioral Change

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2022-07-28

Completion:

2024-03-25

Conditions

• Risk Reduction
• Environmental Exposure
• Risk Behavior, Health

Interventions

• DEVICE

Results Available

NCT05324579 | COMPLETED | NA

20 participants

Studying the Neuronal Basis of Human Social Cognition

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2022-05-20

Completion:

2026-08-01

Conditions

• Neurosciences

Interventions

• BEHAVIORAL

No Results Yet

NCT05309694 | COMPLETED | PHASE4

119 participants

A Study to Assess the Safety of a New Inserter Device for Paragard® (Intrauterine Copper Contraceptive)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2022-03-04

Completion:

2022-12-08

Conditions

• Contraception

Interventions

• COMBINATION_PRODUCT

Results Available

NCT05304585 | RECRUITING | PHASE3

205 participants

Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2022-08-04

Completion:

2030-06-30

Conditions

• Embryonal Rhabdomyosarcoma
• Fusion-Negative Alveolar Rhabdomyosarcoma
• Spindle Cell/Sclerosing Rhabdomyosarcoma

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL
• RADIATION

No Results Yet

NCT05286112 | COMPLETED | NA

76 participants

Mindfulness for Pain and Suicide

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2023-03-06

Completion:

2026-02-28

Conditions

• Chronic Pain
• Suicidal Ideation
• Suicide, Attempted
• Opioid Use

Interventions

• BEHAVIORAL

Results Available

NCT05235165 | RECRUITING | PHASE3

62 participants

Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2022-04-01

Completion:

2031-03-31

Conditions

• Metastatic Malignant Neoplasm in the Lung
• Metastatic Osteosarcoma
• Osteosarcoma

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT05224102 | ACTIVE_NOT_RECRUITING | PHASE4

218 participants

A Study to Investigate Faricimab Treatment Response in Treatment-Naive, Underrepresented Patients With Diabetic Macular Edema

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2022-02-28

Completion:

2027-01-26

Conditions

• Diabetic Macular Edema

Interventions

• DRUG

No Results Yet

NCT05198245 | ACTIVE_NOT_RECRUITING

1 participants

Study of Pregnancy Outcomes in Women Exposed to Rimegepant During Pregnancy

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-25

Start Date:

2021-12-15

Completion:

2028-04-17

Conditions

• Migraine

Interventions

• DRUG
• OTHER

No Results Yet

NCT05129488 | COMPLETED | NA

33 participants

Biotrue ONEday Contact Lenses With EPG03 Packaging Solution Compared to Biotrue ONEday Contact Lenses

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2021-09-15

Completion:

2021-09-20

Conditions

• Contact Lens Wearer

Interventions

• DEVICE

Results Available

NCT05120869 | COMPLETED | NA

161 participants

Healthcare Provider Human Papillomavirus Education and Professional Skills Intervention

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2023-12-22

Completion:

2024-12-02

Conditions

• Health Personnel Attitude
• Health Knowledge, Attitudes, Practice

Interventions

• BEHAVIORAL

Results Available

NCT05120505 | COMPLETED | PHASE4

37 participants

Metformin in Children With Fragile X Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2021-12-29

Completion:

2025-01-30

Conditions

• Fragile X Syndrome
• Metformin

Interventions

• DRUG

No Results Yet

NCT05098236 | COMPLETED | NA

280 participants

Effect of Visual Retraining on Visual Loss Following Visual Cortical Damage

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2003-09-26

Completion:

2024-06-04

Conditions

• Vision Loss Partial
• Hemianopia
• Hemianopia Homonymous
• Quadrantanopia
• Stroke, Ischemic

Interventions

• OTHER

No Results Yet

NCT05054790 | NOT_YET_RECRUITING | PHASE2

10 participants

Augmentation Cystoplasty Using an Autologous Neo-Bladder Construct

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2027-12-31

Completion:

2028-12-31

Conditions

• Contracted Bladder

Interventions

• BIOLOGICAL

No Results Yet

NCT05050136 | ACTIVE_NOT_RECRUITING | PHASE2

333 participants

A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Biliary Cholangitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2021-09-22

Completion:

2027-01-31

Conditions

• Primary Biliary Cholangitis
• PBC

Interventions

• DRUG

No Results Yet

NCT05041140 | RECRUITING

25 participants

Hyperpolarized 129-Xenon Imaging in Adult Hematopoietic Cell Transplant Recipients With Pulmonary Impairment

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-25

Start Date:

2024-08-14

Completion:

2027-07-20

Conditions

• Pulmonary
• Pneumonia
• Hematopoietic System--Cancer

Interventions

• DEVICE

No Results Yet

NCT05039281 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

47 participants

Atezolizumab and Cabozantinib for the Treatment of Recurrent Glioblastoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2022-09-23

Completion:

2027-12-31

Conditions

• Recurrent Glioblastoma
• Recurrent Gliosarcoma

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT05030428 | ACTIVE_NOT_RECRUITING | PHASE3

17004 participants

Study of Inclisiran to Prevent Cardiovascular (CV) Events in Participants With Established Cardiovascular Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2021-11-23

Completion:

2027-05-10

Conditions

• Atherosclerotic Cardiovascular Disease

Interventions

• DRUG

No Results Yet

NCT05028738 | ACTIVE_NOT_RECRUITING | NA

100 participants

Patient-oriented Randomized Pragmatic Feasibility Trial With rTMS in Depression and Anxiety

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2021-10-11

Completion:

2026-08-01

Conditions

• Major Depressive Episode
• Major Depressive Disorder

Interventions

• DEVICE

No Results Yet

NCT05012982 | COMPLETED | NA

18 participants

Immunometabolic Mechanisms of Blood Flow Restriction (BFR) Training After Anterior Cruciate Ligament Reconstruction

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2023-02-16

Completion:

2026-05-15

Conditions

• Anterior Cruciate Ligament Reconstruction

Interventions

• DEVICE

No Results Yet

NCT04999553 | RECRUITING | NA

480 participants

Left vs. Right Non-Inferiority Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2021-11-08

Completion:

2027-06-01

Conditions

• Depression
• Major Depressive Disorder
• Major Depressive Episode

Interventions

• DEVICE

No Results Yet

NCT04943497 | COMPLETED

2390 participants

A Prospective Observational Study to Describe Clinical Outcomes, Treatment Patterns, Patients Characteristics Among Patients With HR+/HER2- Advanced BC Initiating Treatment With Risarg®, Piqray®, Endocrine Therapy or Chemotherapy in Routine Clinical Practice in Russia

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-25

Start Date:

2021-07-27

Completion:

2025-07-28

Conditions

• Breast Cancer

Interventions

• OTHER

No Results Yet

NCT04941274 | RECRUITING | PHASE1/PHASE2

111 participants

Abemaciclib in Patients With HIV-associated and HIV-negative Kaposi Sarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2021-09-29

Completion:

2028-03-01

Conditions

• Kaposi Sarcoma

Interventions

• DRUG

No Results Yet

NCT04902443 | RECRUITING | PHASE1

58 participants

Pomalidomide and Nivolumab in People With Virus-Associated Malignancies With or Without HIV

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2021-12-10

Completion:

2026-12-01

Conditions

• Viral Associated Malignancies
• Kaposi Sarcoma
• EBV/KSHV-associated Lymphomas

Interventions

• DRUG

No Results Yet

NCT04876248 | ACTIVE_NOT_RECRUITING | PHASE2

4 participants

Belantamab Mafodotin and Lenalidomide for the Treatment of Multiple Myeloma in Patients With Minimal Residual Disease Positive After Stem Cell Transplant

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2024-08-19

Completion:

2026-10-21

Conditions

• Plasma Cell Myeloma

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT04874480 | ACTIVE_NOT_RECRUITING | PHASE1

9 participants

Tegavivint for the Treatment of Relapsed or Refractory Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2021-09-27

Completion:

2027-02-02

Conditions

• Recurrent Leukemia
• Refractory Leukemia

Interventions

• DRUG

No Results Yet

NCT04870944 | SUSPENDED | PHASE1/PHASE2

63 participants

CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2022-01-28

Completion:

2026-12-31

Conditions

• Diffuse Midline Glioma, H3 K27-Altered
• Metastatic Malignant Neoplasm in the Central Nervous System
• Recurrent Diffuse Intrinsic Pontine Glioma
• Recurrent Diffuse Midline Glioma, H3 K27-Altered
• Recurrent Lymphoma
• Recurrent Malignant Solid Neoplasm
• Recurrent Primary Malignant Central Nervous System Neoplasm
• Refractory Lymphoma
• Refractory Malignant Solid Neoplasm
• Refractory Primary Malignant Central Nervous System Neoplasm

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT04852601 | COMPLETED | NA

35403 participants

ToolBox Detect: Low Cost Detection of Cognitive Decline in Primary Care Settings

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2022-08-25

Completion:

2026-02-28

Conditions

• Cognitive Dysfunction
• Dementia

Interventions

• OTHER

No Results Yet

NCT04851119 | RECRUITING | PHASE1/PHASE2

147 participants

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2021-11-08

Completion:

2028-06-30

Conditions

• Colorectal Carcinoma
• Endometrial Carcinoma
• Melanoma
• Neuroblastoma
• Ovarian Carcinoma
• Pancreatic Ductal Adenocarcinoma
• Recurrent Desmoid Fibromatosis
• Recurrent Ewing Sarcoma
• Recurrent Hepatoblastoma
• Recurrent Hepatocellular Carcinoma
• Recurrent Malignant Solid Neoplasm
• Recurrent Non-Hodgkin Lymphoma
• Recurrent Osteosarcoma
• Refractory Desmoid Fibromatosis
• Refractory Ewing Sarcoma
• Refractory Hepatoblastoma
• Refractory Hepatocellular Carcinoma
• Refractory Malignant Solid Neoplasm
• Refractory Non-Hodgkin Lymphoma
• Refractory Osteosarcoma
• Solid Pseudopapillary Neoplasm of the Pancreas
• Wilms Tumor

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT04847063 | RECRUITING | PHASE1

60 participants

Individual Response to Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Treatment of Peritoneal Carcinomatosis From Peritoneal Mesothelioma or Atypical Mesothelial Proliferation or From Ovarian, Colorectal, or Appendiceal Histologies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2021-10-19

Completion:

2033-12-30

Conditions

• Peritoneal Mesothelioma
• Peritoneal Carcinomatosis
• Ovarian Cancer
• Gastrointestinal Cancer
• Appendiceal Cancer
• Atypical Mesothelial Proliferation
• Colorectal Cancer

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT04838041 | RECRUITING | PHASE2

51 participants

Protocol Number: HJKC3-0003. Treatment Free Remission After Asciminib Based Therapy in Chronic Phase Chronic Myeloid Leukemia (CP-CML) Patients Who Relapsed After a Prior Attempt at TKI Discontinuation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2021-11-11

Completion:

2028-06-30

Conditions

• Chronic Phase Chronic Myelogenous Leukemia

Interventions

• DRUG

No Results Yet

NCT04808427 | SUSPENDED | NA

21 participants

Pilot Study to Investigate Magnetic Resonance (MR) Image Guided Focal Therapy in Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2023-11-20

Completion:

2027-05-01

Conditions

• Prostate Cancer

Interventions

• DEVICE

No Results Yet

NCT04801771 | ACTIVE_NOT_RECRUITING | NA

57 participants

Effects of Hypoglossal Nerve Stimulation on Cognition and Language in Down Syndrome and Obstructive Sleep Apnea

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2021-06-24

Completion:

2026-07-01

Conditions

• Down Syndrome
• Obstructive Sleep Apnea

Interventions

• DEVICE

No Results Yet

NCT04770896 | ACTIVE_NOT_RECRUITING | PHASE3

557 participants

A Study of Atezolizumab With Lenvatinib or Sorafenib Versus Lenvatinib or Sorafenib Alone in Hepatocellular Carcinoma Previously Treated With Atezolizumab and Bevacizumab

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2021-04-26

Completion:

2026-10-14

Conditions

• Unresectable Hepatocellular Carcinoma

Interventions

• DRUG

No Results Yet