Clinical Trials

NCT04179175 | COMPLETED | PHASE3

702 participants

Extension Study to Assess Effects of Non-interrupted Versus Interrupted and Long Term Treatment of Two Dose Regimes of Secukinumab in Subjects With Hidradenitis Suppurativa

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2020-03-18

Completion:

2023-05-26

Conditions

• Hidradenitis Suppurativa

Interventions

• DRUG

Results Available

NCT04147494 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

29 participants

Experimental PET Imaging Scans Before Cancer Surgery to Study the Amount of PET Tracer Accumulated in Normal and Cancer Tissues

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2019-11-05

Completion:

2030-06-01

Conditions

• Breast Carcinoma
• Colon Carcinoma
• Esophageal Carcinoma
• Gastric Carcinoma
• Head and Neck Carcinoma
• Kidney Carcinoma
• Lung Carcinoma
• Ovarian Carcinoma
• Pancreatic Carcinoma
• Solid Neoplasm
• Uterine Corpus Cancer

Interventions

• PROCEDURE
• RADIATION

No Results Yet

NCT04133909 | COMPLETED | PHASE3

806 participants

Mepolizumab as Add-on Treatment IN Participants With COPD Characterized by Frequent Exacerbations and Eosinophil Level

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2019-10-30

Completion:

2024-08-08

Conditions

• Pulmonary Disease, Chronic Obstructive

Interventions

• BIOLOGICAL
• DRUG

Results Available

NCT04130997 | ACTIVE_NOT_RECRUITING | PHASE3

1100 participants

An Extension Study of Ublituximab in Participants With Relapsing Multiple Sclerosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2019-11-18

Completion:

2032-05-31

Conditions

• Relapsing Multiple Sclerosis (RMS)

Interventions

• BIOLOGICAL

No Results Yet

NCT04106219 | ACTIVE_NOT_RECRUITING | PHASE1

71 participants

A Study of LY3295668 Erbumine in Participants With Relapsed/Refractory Neuroblastoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2020-06-11

Completion:

2022-04-13

Conditions

• Neuroblastoma

Interventions

• DRUG

No Results Yet

NCT04102423 | RECRUITING

306 participants

CHIP/CCUS Natural History Protocol

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-21

Start Date:

2020-03-03

Completion:

2033-09-15

Conditions

• Clonal Hematopoiesis of Indeterminate Potential
• Clonal Cytopenia of Undetermined Significance

No Results Yet

NCT04070027 | ACTIVE_NOT_RECRUITING | NA

109 participants

Progressive Resistance Training Versus Total Hip Arthroplasty in Patients With Hip Osteoarthritis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2019-09-02

Completion:

2022-05-05

Conditions

• Hip Osteoarthritis

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT04069312 | COMPLETED | PHASE3

1032 participants

Roflumilast or Azithromycin to Prevent COPD Exacerbations Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2020-02-11

Completion:

2026-03-01

Conditions

• Chronic Obstructive Pulmonary Disease Severe
• Chronic Bronchitis

Interventions

• DRUG

No Results Yet

NCT04068194 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

103 participants

Testing the Combination of New Anti-cancer Drug Peposertib With Avelumab and Radiation Therapy for Advanced/Metastatic Solid Tumors and Hepatobiliary Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2020-04-07

Completion:

2027-07-01

Conditions

• Locally Advanced Malignant Solid Neoplasm
• Locally Advanced Unresectable Cholangiocarcinoma
• Locally Advanced Unresectable Gallbladder Carcinoma
• Locally Advanced Unresectable Malignant Solid Neoplasm
• Metastatic Cholangiocarcinoma
• Metastatic Gallbladder Carcinoma
• Metastatic Malignant Solid Neoplasm
• Stage III Gallbladder Cancer AJCC v8
• Stage IV Gallbladder Cancer AJCC v8
• Unresectable Malignant Solid Neoplasm

Interventions

• DRUG
• PROCEDURE
• RADIATION

No Results Yet

NCT04045210 | COMPLETED | NA

274 participants

Psychological Support Based on Positive Suggestions (PSBPS) on Mental Health Morbidity and Cognitive Function

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2019-08-30

Completion:

2025-01-31

Conditions

• Critical Illness

Interventions

• OTHER

Results Available

NCT04023487 | COMPLETED | NA

209 participants

Evaluation of an Intervention for Young Adults With Diabetes: Resilient, Empowered, Active Living-Telehealth (REAL-T)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2019-10-22

Completion:

2023-06-05

Conditions

• Diabetes Mellitus, Type 1

Interventions

• BEHAVIORAL

Results Available

NCT04021108 | ACTIVE_NOT_RECRUITING | PHASE2

80 participants

Phase II Study of Short Course FOLFOX Chemotherapy With Either Nivolumab or Nivolumab + Radiation in the First Line Treatment of Metastatic or Unresectable Gastroesophageal Cancers (BMS Protocol CA209-76L)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2019-07-22

Completion:

2025-06-11

Conditions

• Gastroesophageal Adenocarcinoma

Interventions

• DRUG

Results Available

NCT04002271 | WITHDRAWN | PHASE4

0 participants

Total Knee Replacement TIVA With Robotic Arm Assisted

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2020-07-22

Completion:

2023-12-31

Conditions

• Postoperative Pain

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT03992404 | ACTIVE_NOT_RECRUITING | PHASE3

603 participants

Study to Compare the Efficacy and Safety of NT 201 (Botulinum Toxin) With Placebo for the Treatment of Lower Limb Spasticity Caused by Stroke or Traumatic Brain Injury

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2019-09-16

Completion:

2025-06-19

Conditions

• Lower Limb or Combined Lower Limb and Upper Limb Spasticity Due to Stroke or Traumatic Brain Injury

Interventions

• DRUG

No Results Yet

NCT03969329 | RECRUITING | PHASE3

24 participants

A Phase 3 Study of Etelcalcetide in Children With Secondary Hyperparathyroidism Receiving Hemodialysis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2019-12-20

Completion:

2027-06-30

Conditions

• Secondary Hyperparathyroidism

Interventions

• DRUG

No Results Yet

NCT03965234 | RECRUITING | PHASE1/PHASE2

99 participants

Pulmonary Suffusion in Controlling Minimal Residual Disease in Patients With Sarcoma or Colorectal Metastases

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2020-07-16

Completion:

2029-05-25

Conditions

• Metastatic Bone Sarcoma
• Metastatic Malignant Neoplasm in the Lung
• Metastatic Soft Tissue Sarcoma
• Metastatic Unresectable Sarcoma
• Resectable Sarcoma
• Colorectal Cancer

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT03962569 | COMPLETED

25 participants

Early Activation of Artificial Urinary Sphincter

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-21

Start Date:

2019-08-01

Completion:

2023-10-31

Conditions

• Incontinence, Urinary

No Results Yet

NCT03940703 | COMPLETED | PHASE2

140 participants

A Study of Tepotinib Plus Osimertinib in Osimertinib Relapsed MET Amplified NSCLC (INSIGHT 2)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2019-09-19

Completion:

2023-05-11

Conditions

• Non-small Cell Lung Cancer

Interventions

• DRUG

Results Available

NCT03921541 | COMPLETED | PHASE3

32 participants

Efficacy and Safety of Pegzilarginase in Patients With Arginase 1 Deficiency

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2019-05-01

Completion:

2023-02-01

Conditions

• Arginase I Deficiency
• Hyperargininemia

Interventions

• DRUG

Results Available

NCT03899025 | COMPLETED | NA

91 participants

Diagnostics of Scaphoid Fractures With HRpQCT

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2017-12-12

Completion:

2019-11-28

Conditions

• Scaphoid Fracture
• Scafoïd; Fracture

Interventions

• RADIATION

No Results Yet

NCT03890601 | COMPLETED

74 participants

New Biological Tests in Patients With Antiphospholipid Antibodies

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-21

Start Date:

2019-03-13

Completion:

2023-05-22

Conditions

• Antiphospholipid Syndrome

Interventions

• BIOLOGICAL

No Results Yet

NCT03884998 | ACTIVE_NOT_RECRUITING | PHASE1

27 participants

Copanlisib and Nivolumab in Treating Patients With Richter's Transformation or Transformed Indolent Non-Hodgkin Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2019-07-10

Completion:

2026-11-04

Conditions

• Chronic Lymphocytic Leukemia
• Diffuse Large B-Cell Lymphoma
• Follicular Lymphoma
• Indolent Non-Hodgkin Lymphoma
• Lymphoplasmacytic Lymphoma
• Marginal Zone Lymphoma
• Richter Syndrome

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT03876314 | COMPLETED | NA

180 participants

Physical Activity, Alzheimer's Disease and Cognition Relative to APOE Genotype

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2019-05-23

Completion:

2024-12-21

Conditions

• Healthy
• Dementia
• Alzheimer Disease
• Physical Activity

Interventions

• BEHAVIORAL

Results Available

NCT03842007 | RECRUITING | NA

160 participants

Understanding Mechanisms of Normal and Disordered Defecation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2019-01-29

Completion:

2028-12-31

Conditions

• Constipation

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT03764553 | ACTIVE_NOT_RECRUITING | PHASE2

320 participants

Liposomal iRInotecan, Carboplatin or oXaliplatin for Esophagogastric Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2019-05-01

Completion:

2025-07-31

Conditions

• Esophageal Cancer

Interventions

• DRUG

No Results Yet

NCT03740334 | ACTIVE_NOT_RECRUITING | PHASE1

45 participants

Ribociclib in Combination With Everolimus and Dexamethasone in Relapsed ALL

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2019-01-30

Completion:

2023-03-04

Conditions

• Acute Lymphoblastic Leukemia ALL

Interventions

• DRUG

No Results Yet

NCT03728335 | SUSPENDED | PHASE2

35 participants

Enasidenib (AG-221) Maintenance Post Allogeneic HCT in Patients With IDH2 Mutation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2019-12-23

Completion:

2027-01-11

Conditions

• Acute Myeloid Leukemia

Interventions

• DRUG

No Results Yet

NCT03705416 | ACTIVE_NOT_RECRUITING

250 participants

Long Term Outcomes of Bariatric Patients Treated With Surgery or Endoscopy

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-21

Start Date:

2019-03-30

Completion:

2026-12-31

Conditions

• GERD
• Obesity

Interventions

• PROCEDURE

No Results Yet

NCT03663361 | COMPLETED | NA

43 participants

Addressing Neuromuscular Deficits for Improved Outcomes in Ankle Rehabilitation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2019-11-12

Completion:

2026-05-06

Conditions

• Ankle Sprains

Interventions

• OTHER

No Results Yet

NCT03655002 | ACTIVE_NOT_RECRUITING | PHASE1

8 participants

IRX-2, Cyclophosphamide, and Nivolumab in Treating Patients With Recurrent or Metastatic and Refractory Liver Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2019-05-17

Completion:

2027-03-02

Conditions

• Recurrent Hepatocellular Carcinoma
• Refractory Liver Carcinoma
• Stage IV Hepatocellular Carcinoma AJCC v8
• Stage IVA Hepatocellular Carcinoma AJCC v8
• Stage IVB Hepatocellular Carcinoma AJCC v8

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT03589846 | ENROLLING_BY_INVITATION | NA

60 participants

Muscle Stimulation During DISE

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2018-07-26

Completion:

2028-12-31

Conditions

• Obstructive Sleep Apnea

Interventions

• DEVICE

No Results Yet

NCT03567213 | RECRUITING | NA

3 participants

Investigation on the Cortical Communication (CortiCom) System

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2021-12-14

Completion:

2028-12-31

Conditions

• Tetraplegia
• Locked-in Syndrome
• Brainstem Stroke
• Amyotrophic Lateral Sclerosis

Interventions

• DEVICE

No Results Yet

NCT03538639 | RECRUITING

1000 participants

Vascular Disease Discovery Protocol

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-21

Start Date:

2018-07-30

Completion:

2027-11-30

Conditions

• Vascular Dysfunction
• Genetic Mutations
• Genetic Predisposition

No Results Yet

NCT03530397 | ACTIVE_NOT_RECRUITING | PHASE1

400 participants

A Study to Evaluate MEDI5752 in Subjects With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2018-04-24

Completion:

2025-07-14

Conditions

• Selected Advanced Solid Tumors

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT03504956 | RECRUITING | NA

150 participants

Coronary Atherosclerosis T1-Weighted Characterization (CATCH)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2018-07-30

Completion:

2027-06-30

Conditions

• Coronary Atherosclerosis

Interventions

• DEVICE
• DRUG

No Results Yet

NCT03492372 | ENROLLING_BY_INVITATION

300 participants

Molecular Characterization of Spinal Tissue

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-21

Start Date:

2015-03-31

Completion:

2027-07-31

Conditions

• Spinal Diseases

Interventions

• OTHER

No Results Yet

NCT03417544 | COMPLETED | PHASE2

19 participants

Atezolizumab + Pertuzumab + Trastuzumab In CNS Mets In BC

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2018-05-21

Completion:

2020-05-20

Conditions

• HER2-positive Metastatic Breast Cancer
• Central Nervous System Metastases

Interventions

• DRUG

Results Available

NCT03301792 | ACTIVE_NOT_RECRUITING | NA

117 participants

Group Versus Traditional Prenatal Care for Diabetes

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2017-09-14

Completion:

2025-11-17

Conditions

• Pregnancy
• Gestational Diabetes
• Type 2 Diabetes

Interventions

• BEHAVIORAL

No Results Yet

NCT03208868 | RECRUITING | NA

32 participants

Leucine Enriched Essential Amino Acid Mixture to Reverse Muscle Loss in Cirrhosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2013-08-05

Completion:

2028-12-31

Conditions

• Cirrhosis, Liver

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT03188432 | COMPLETED | PHASE2

50 participants

Hyperthermic Intraperitoneal Chemotherapy Trial Comparing Quality of Life in Patients With Stage IIIC-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2019-01-02

Completion:

2024-01-31

Conditions

• Stage IIIC Fallopian Tube Cancer
• Stage IIIC Ovarian Cancer
• Stage IIIC Primary Peritoneal Cancer
• Stage IV Fallopian Tube Cancer
• Stage IV Ovarian Cancer
• Stage IV Primary Peritoneal Cancer

Interventions

• DRUG
• OTHER
• PROCEDURE

Results Available