Clinical Trials

NCT04417062 | ACTIVE_NOT_RECRUITING | PHASE2

49 participants

Olaparib With Ceralasertib in Recurrent Osteosarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2020-11-24

Completion:

2025-06-01

Conditions

• Osteosarcoma
• Osteosarcoma Recurrent

Interventions

• DRUG

Results Available

NCT04410302 | RECRUITING

500 participants

Patient-Derived Xenografts to Reduce Cancer Health Disparities

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-20

Start Date:

2019-11-12

Completion:

2026-12-31

Conditions

• Bladder Carcinoma
• Gastric Carcinoma
• Liver and Intrahepatic Bile Duct Carcinoma
• Lung Carcinoma
• Malignant Neoplasm

Interventions

• PROCEDURE

No Results Yet

NCT04408950 | COMPLETED

19 participants

Sample Collection for Systems Evaluation of Patients With Unknown or Incompletely Characterized Immune Defects

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-20

Start Date:

2020-11-12

Completion:

2025-01-27

Conditions

• Immunodeficiency

No Results Yet

NCT04404088 | ACTIVE_NOT_RECRUITING | PHASE2

60 participants

Acalabrutinib, Lenalidomide, and Rituximab for the Treatment of CD20 Positive Stage III-IV, Grade 1-3a Follicular Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2020-07-16

Completion:

2028-03-01

Conditions

• Ann Arbor Stage III Grade 1 Follicular Lymphoma
• Ann Arbor Stage III Grade 2 Follicular Lymphoma
• Ann Arbor Stage III Grade 3 Follicular Lymphoma
• Ann Arbor Stage IV Grade 1 Follicular Lymphoma
• Ann Arbor Stage IV Grade 2 Follicular Lymphoma
• Ann Arbor Stage IV Grade 3 Follicular Lymphoma
• Grade 3a Follicular Lymphoma

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT04388605 | ACTIVE_NOT_RECRUITING

7965 participants

Assessing the Safety of Pregnancy In the CoRonavirus (COVID-19) pandEmic

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-20

Start Date:

2020-04-21

Completion:

2026-12-31

Conditions

• Corona Virus Infection
• COVID
• Pregnancy Related
• Early Pregnancy

No Results Yet

NCT04355572 | RECRUITING | NA

60 participants

Evaluation of the Clinical and Psychological Impact of Vitamin D Replacement in Adolescent Females at Risk for Polycystic Ovarian Syndrome (PCOS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2026-09-30

Completion:

2028-08-31

Conditions

• Polycystic Ovarian Syndrome in Adolescent Females
• Vitamin D Deficiency

Interventions

• DRUG

No Results Yet

NCT04335994 | RECRUITING | NA

200 participants

ENhancing Outcomes in Cognitive Impairment Through Use of Home Sleep ApNea Testing

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2019-09-23

Completion:

2026-12-31

Conditions

• Obstructive Sleep Apnea
• Alzheimer Disease
• Vascular Dementia
• Mild Cognitive Impairment
• Parkinsons Disease With Dementia
• Dementia With Lewy Bodies
• Mixed Dementia

Interventions

• DEVICE

No Results Yet

NCT04318808 | COMPLETED | NA

40 participants

Effect of Laser Acupuncture on Constipation in Patients With Advanced Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2020-03-30

Completion:

2022-02-28

Conditions

• Constipation
• Advanced Cancer

Interventions

• PROCEDURE

No Results Yet

NCT04311437 | COMPLETED | NA

152 participants

Effect of Self-acupressure on Middle Ear Barotrauma Associated With Hyperbaric Oxygen Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2020-03-01

Completion:

2023-02-28

Conditions

• Hyperbaric Oxygen Therapy
• Middle Ear Barotrauma

Interventions

• PROCEDURE

No Results Yet

NCT04292574 | RECRUITING

800 participants

UK SMA Patient Registry

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-20

Start Date:

2008-07-13

Completion:

2040-01-01

Conditions

• Spinal Muscular Atrophy
• SMA

Interventions

• OTHER

No Results Yet

NCT04271956 | RECRUITING | PHASE2

83 participants

Efficacy and Safety of Zanubrutinib Plus Tislelizumab Treatment With or Without Sonrotoclax for Patients With Richter Transformation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2020-02-19

Completion:

2027-08-31

Conditions

• Richter Transformation

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT04222023 | COMPLETED | PHASE4

359 participants

Intravenous Immunoglobulins for Prevention of BKV Infection in Kidney Transplant Recipients According to BKV Genotype-specific Neutralizing Antibody Titers at the Day of Transplantation.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2022-08-21

Completion:

2026-08-01

Conditions

• Kidney Transplantation

Interventions

• DRUG

No Results Yet

NCT04220021 | ACTIVE_NOT_RECRUITING | PHASE2

41 participants

Safety and Therapeutic Potential of the FDA-approved Drug Metformin for C9orf72 ALS/FTD

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2020-01-10

Completion:

2024-08-26

Conditions

• C9orf72 Amyotrophic Lateral Sclerosis (ALS)
• Frontotemporal Dementia

Interventions

• DRUG

Results Available

NCT04205968 | RECRUITING | PHASE2

94 participants

Ramucirumab and Paclitaxel or FOLFIRI in Advanced Small Bowel Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2020-06-01

Completion:

2027-02-01

Conditions

• Metastatic Small Intestinal Adenocarcinoma
• Stage III Small Intestinal Adenocarcinoma AJCC v8
• Stage IIIA Small Intestinal Adenocarcinoma AJCC v8
• Stage IIIB Small Intestinal Adenocarcinoma AJCC v8
• Stage IV Small Intestinal Adenocarcinoma AJCC v8

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT04199780 | COMPLETED | NA

106 participants

Effects of tDCS Combined With CBI on Postsurgical Pain

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2021-01-11

Completion:

2026-01-01

Conditions

• Total Knee Arthroplasty (Postoperative Pain)
• Total Hip Arthroplasty (Postoperative Pain)

Interventions

• DEVICE
• BEHAVIORAL

No Results Yet

NCT04159597 | AVAILABLE

Expanded Access to Upadacitinib

Study Type:

EXPANDED_ACCESS

Last Updated:

2026-08-20

Conditions

• Crohn Disease
• Ulcerative Colitis
• Idiopathic Arthritis (Including sJIA, pJIA, or JPsA)
• Atopic Dermatitis
• Rheumatoid Arthritis
• Psoriatic Arthritis
• Axial Spondyloarthritis
• Non-radiographic Axial
• Spondyloarthritis
• Giant Cell Arteritis
• Systemic Lupus Erythematosus
• Alopecia Areata
• Non Segmental Vitiligo
• Hidradenitis Suppurativa

Interventions

• DRUG

No Results Yet

NCT04159298 | COMPLETED | NA

58 participants

Cervicogenic Concussion Rehabilitation With TopSpin360

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2022-05-06

Completion:

2023-12-12

Conditions

• Concussion, Mild

Interventions

• DEVICE

No Results Yet

NCT04151667 | COMPLETED | PHASE2

33 participants

Daratumumab Based Response Adapted Therapy for Older Adults With Newly Diagnosed Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2019-11-22

Completion:

2023-11-08

Conditions

• Multiple Myeloma

Interventions

• DRUG

Results Available

NCT04150198 | RECRUITING | NA

45 participants

MECHANISMS OF NEURONAL RESILIENCE IN ALZHEIMER'S DISEASE AND ITS FOCAL VARIANTS: A PET/MR STUDY

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2021-12-08

Completion:

2028-12-31

Conditions

• Alzheimer Disease, Early Onset
• Posterior Cortical Atrophy

Interventions

• DEVICE

No Results Yet

NCT04124965 | COMPLETED | PHASE3

71 participants

A Study to Investigate the Long-term Safety, Tolerability, and Efficacy of Rozanolixizumab in Adult Patients With Generalized Myasthenia Gravis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2019-10-29

Completion:

2021-09-01

Conditions

• Generalized Myasthenia Gravis

Interventions

• DRUG

Results Available

NCT04112641 | ACTIVE_NOT_RECRUITING | PHASE2

48 participants

NIAGEN and Persistent Chemotherapy-Induced Peripheral Neuropathy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2020-02-19

Completion:

2027-06-28

Conditions

• Chemotherapy-induced Peripheral Neuropathy

Interventions

• DRUG

No Results Yet

NCT04076462 | COMPLETED | PHASE3

72 participants

A Trial to Assess Efficacy and Safety of Octreotide Subcutaneous Depot in Patients With Acromegaly

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2019-08-19

Completion:

2023-05-02

Conditions

• Acromegaly

Interventions

• DRUG

Results Available

NCT04064593 | COMPLETED | NA

2007 participants

Sleep Disordered Breathing (SDB) Prevalence and Cardiovascular Outcomes of Myocardial Infarction (MI) Survivors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2019-04-09

Completion:

2023-12-03

Conditions

• Acute Myocardial Infarction
• Sleep Apnea

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04057833 | ACTIVE_NOT_RECRUITING | PHASE1

20 participants

E-CEL UVEC Cells as an Adjunct Cell Therapy for the Arthroscopic Rotator Cuff Repair in Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2019-11-20

Completion:

2026-10-31

Conditions

• Rotator Cuff Tears
• Muscle Atrophy or Weakness
• Tendon Rupture - Shoulder
• Safety Issues

Interventions

• DRUG

No Results Yet

NCT04034550 | ACTIVE_NOT_RECRUITING | NA

200 participants

Cohort of Hospitalized Patients Suspected of Leptospirosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2021-01-06

Completion:

2026-09-06

Conditions

• Leptospirosis

Interventions

• OTHER

No Results Yet

NCT04021355 | COMPLETED | NA

61 participants

Timing of Sodium Intake and Nocturnal Sodium Excretion and Blood Pressure in Obese African Americans

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2020-11-14

Completion:

2025-06-14

Conditions

• Obesity
• Hypertension
• Circadian Dysregulation
• Salt; Excess

Interventions

• OTHER

Results Available

NCT04018625 | COMPLETED | NA

63 participants

The Stony Brook University Calm-Mom Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2021-04-01

Completion:

2023-06-01

Conditions

• Pregnancy Related
• Stress, Psychological
• Anxiety
• Perinatal Depression

Interventions

• BEHAVIORAL

Results Available

NCT04008030 | ACTIVE_NOT_RECRUITING | PHASE3

839 participants

A Study of Nivolumab, Nivolumab Plus Ipilimumab, or Investigator's Choice Chemotherapy for the Treatment of Participants With Deficient Mismatch Repair (dMMR)/Microsatellite Instability High (MSI-H) Metastatic Colorectal Cancer (mCRC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2019-08-05

Completion:

2024-08-28

Conditions

• Metastatic Colorectal Cancer

Interventions

• BIOLOGICAL
• DRUG

Results Available

NCT04007029 | ACTIVE_NOT_RECRUITING | PHASE1

24 participants

Modified Immune Cells (CD19/CD20 CAR-T Cells) in Treating Patients With Recurrent or Refractory B-Cell Lymphoma or Chronic Lymphocytic Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2019-10-04

Completion:

2027-08-01

Conditions

• CD19 Positive
• CD20 Positive
• Recurrent Chronic Lymphocytic Leukemia
• Recurrent Diffuse Large B-Cell Lymphoma
• Recurrent Follicular Lymphoma
• Recurrent Mantle Cell Lymphoma
• Recurrent Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma
• Recurrent Small Lymphocytic Lymphoma
• Refractory Chronic Lymphocytic Leukemia
• Refractory Diffuse Large B-Cell Lymphoma
• Refractory Follicular Lymphoma
• Refractory Mantle Cell Lymphoma
• Refractory Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma
• Refractory Small Lymphocytic Lymphoma

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT04001582 | RECRUITING

1018 participants

The United Kingdom Facioscapulohumeral Muscular Dystrophy Patient Registry

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-20

Start Date:

2013-05-31

Completion:

2040-01-31

Conditions

• Facioscapulohumeral Muscular Dystrophy

Interventions

• OTHER

No Results Yet

NCT03971422 | COMPLETED | PHASE3

200 participants

A Study to Test Efficacy and Safety of Rozanolixizumab in Adult Patients With Generalized Myasthenia Gravis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2019-06-03

Completion:

2021-08-31

Conditions

• Generalized Myasthenia Gravis

Interventions

• DRUG
• OTHER

Results Available

NCT03964454 | COMPLETED | NA

168 participants

BOOST: Breastfeeding Onset and Onward With Support Tools

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2019-06-19

Completion:

2023-04-18

Conditions

• Breastfeeding Duration

Interventions

• BEHAVIORAL

Results Available

NCT03954678 | RECRUITING | NA

400 participants

Exercise in Patients Undergoing Urologic Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2019-07-30

Completion:

2028-07-31

Conditions

• Perioperative Complication

Interventions

• BEHAVIORAL
• DIETARY_SUPPLEMENT

No Results Yet

NCT03933904 | ACTIVE_NOT_RECRUITING | PHASE2

7 participants

Sirolimus in Previously Treated Idiopathic Multicentric Castleman Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2019-09-25

Completion:

2024-06-30

Conditions

• Castleman Disease
• Castleman's Disease, Multicentric

Interventions

• DRUG

Results Available

NCT03932773 | RECRUITING | NA

330 participants

Multi-site Confirmatory Efficacy Treatment Trial of Combat-related PTSD

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2019-05-01

Completion:

2028-01-01

Conditions

• Post Traumatic Stress Disorder

Interventions

• DEVICE
• BEHAVIORAL

No Results Yet

NCT03915899 | COMPLETED | NA

9080 participants

The Welcome Incoming Neighbor (WIN) Community Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2019-05-01

Completion:

2025-07-01

Conditions

• HIV

Interventions

• BEHAVIORAL

No Results Yet

NCT03911700 | ACTIVE_NOT_RECRUITING | NA

477 participants

Prophylactic Reinforcement of Ventral Abdominal Incisions Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2019-12-12

Completion:

2028-08-31

Conditions

• Open Midline Laparotomy

Interventions

• DEVICE

No Results Yet

NCT03898804 | RECRUITING | NA

12 participants

An Early Feasibility Study of the ReHAB System

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2019-04-09

Completion:

2029-08-01

Conditions

• Tetraplegia

Interventions

• DEVICE

No Results Yet

NCT03845218 | COMPLETED

49 participants

Retinitis Pigmentosa Clinical Measures and Repeatability Testing of Potential Outcome Measures

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-20

Start Date:

2019-09-27

Completion:

2023-07-19

Conditions

• Retinitis Pigmentosa

No Results Yet

NCT03811964 | RECRUITING | NA

726 participants

Photomotor Reflex to Evaluate the Role of the Non-visual Effects of Light in Neurological, Psychiatric and Ophthalmological Pathologies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2020-01-22

Completion:

2028-01-31

Conditions

• Sleep Disorders
• Neurological Pathologies
• Psychiatric Pathologies
• Ophthalmological Pathologies

Interventions

• OTHER

No Results Yet