Clinical Trials

NCT06467357 | RECRUITING | PHASE3

620 participants

Phase 3 Study of T-DXd and Rilvegostomig Versus SoC in Advanced HER2-expressing Biliary Tract Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2024-08-12

Completion:

2028-06-12

Conditions

• Biliary Tract Cancer

Interventions

• DRUG

No Results Yet

NCT06467214 | RECRUITING | NA

264 participants

Increasing Veterans' Social Engagement and Connectedness

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2024-10-04

Completion:

2028-06-30

Conditions

• Social Isolation

Interventions

• BEHAVIORAL

No Results Yet

NCT06465810 | RECRUITING

1850 participants

Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-19

Start Date:

2024-06-25

Completion:

2031-12-29

Conditions

• Transthyretin Amyloidosis
• ATTR-CM
• ATTRv-PN
• ATTR
• ATTR-Mixed
• hATTR

Interventions

• DRUG

No Results Yet

NCT06452277 | RECRUITING | PHASE3

444 participants

A Study to Learn More About How Well Sevabertinib Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2024-08-28

Completion:

2027-10-28

Conditions

• Advanced Non-small Cell Lung Cancer, HER2 Mutation

Interventions

• DRUG

No Results Yet

NCT06445959 | RECRUITING | PHASE1/PHASE2

78 participants

Phase 1b/2 Study of Decitabine and Venetoclax in Combination With the Targeted Mutant IDH1 Inhibitor Olutasidenib

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2024-08-29

Completion:

2027-06-30

Conditions

• Mutant IDH1 Inhibitor Olutasidenib

Interventions

• DRUG

No Results Yet

NCT06444347 | RECRUITING | NA

200 participants

Impact of Biosynthetic Mesh on Paraesophageal Hernia Repair

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2024-06-10

Completion:

2027-07-31

Conditions

• Hiatal Hernia

Interventions

• DEVICE
• PROCEDURE

No Results Yet

NCT06439082 | RECRUITING | PHASE3

354 participants

A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2024-10-24

Completion:

2029-07-02

Conditions

• Sickle Cell Disease

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT06430684 | RECRUITING | EARLY_PHASE1

40 participants

Feasibility Trial of Sodium-GLucose coTransporter 2 INhibitors in Pediatric Chronic KIDney DiSease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2024-08-23

Completion:

2026-09-01

Conditions

• Chronic Kidney Diseases
• Pediatric Kidney Disease

Interventions

• DRUG

No Results Yet

NCT06425549 | ACTIVE_NOT_RECRUITING | PHASE3

176 participants

A Study to Evaluate the Efficacy and Safety of Bimekizumab Compared to Ustekinumab in Children and Adolescents From 6 Years to Less Than 18 Years of Age With Moderate to Severe Plaque Psoriasis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2024-06-25

Completion:

2028-08-21

Conditions

• Moderate to Severe Plaque Psoriasis

Interventions

• DRUG

No Results Yet

NCT06402383 | ACTIVE_NOT_RECRUITING | NA

2000 participants

Supporting the National Expansion of HPV-based Cervical Cancer Screening in Tanzania Among Women Living With HIV

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2024-05-25

Completion:

2027-01-31

Conditions

• Cervical Cancer

Interventions

• BIOLOGICAL

No Results Yet

NCT06399640 | RECRUITING | PHASE1

60 participants

Eltanexor and Venetoclax in Relapsed or Refractory Myelodysplastic Syndrome and Acute Myeloid Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2024-08-14

Completion:

2027-02-01

Conditions

• Relapsed Myelodysplastic Syndrome
• Refractory Myelodysplastic Syndrome
• Acute Myeloid Leukemia
• Recurrent Acute Myeloid Leukemia
• Refractory Acute Myeloid Leukemia

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT06395883 | RECRUITING

160 participants

Dynamics in Bone Turnover Markers During and After Short-term Glucocorticoid Treatment in Patients With an Inflammatory Joint Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-19

Start Date:

2025-01-01

Completion:

2027-10-31

Conditions

• Osteoporosis
• Osteoporosis, Steroid Induced
• Inflammatory Rheumatism

Interventions

• DRUG

No Results Yet

NCT06392711 | RECRUITING | PHASE1

36 participants

Dose-Escalation Trial of Mesenchymal Stromal Cells in Patients With Medical Xerostomia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2024-10-04

Completion:

2028-11-30

Conditions

• Xerostomia
• Graft-versus-host-disease
• Sjogren's Disease

Interventions

• BIOLOGICAL

No Results Yet

NCT06365645 | COMPLETED | NA

90 participants

Feasibility & Acceptability of App-based Cognitive Behavioral Therapy for Postpartum Depression Prevention

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2024-06-07

Completion:

2025-06-14

Conditions

• Postpartum Depression
• Postpartum Anxiety
• Stress

Interventions

• BEHAVIORAL

No Results Yet

NCT06359249 | ACTIVE_NOT_RECRUITING | NA

45 participants

Do the Symptoms of Chronic Constipation Improve With a Primary Care Programme Based on Behavioural Re-education and Abdominal Massage?

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2024-03-01

Completion:

2026-12-28

Conditions

• Constipation Chronic Idiopathic

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT06329661 | COMPLETED | PHASE4

204 participants

A Clinical Trial to Evaluate the Corneal Endothelial Health of DED Subjects Treated With Cyclosporine

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2024-04-22

Completion:

2025-07-30

Conditions

• Dry Eye Disease
• Endothelial Cell

Interventions

• DRUG

Results Available

NCT06326645 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

6 participants

Open-Label Pilot Study With Crofelemer in Patients With Short Bowel Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2025-03-03

Completion:

2026-10-01

Conditions

• Short Bowel Syndrome

Interventions

• DRUG

No Results Yet

NCT06309472 | COMPLETED | PHASE2

76 participants

Trial of Mirtazapine for Depression in IBD

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2024-05-07

Completion:

2025-10-03

Conditions

• Major Depressive Disorder
• Inflammatory Bowel Diseases

Interventions

• DRUG

No Results Yet

NCT06298734 | RECRUITING | NA

40 participants

High-Intensity Exercise and High-Fiber Diet for Immunotherapy Outcomes in Melanoma Patients: The DUO Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2024-07-01

Completion:

2027-07-31

Conditions

• Melanoma (Skin)
• Skin Cancer
• Advanced Melanoma

Interventions

• BEHAVIORAL

No Results Yet

NCT06275126 | RECRUITING | NA

800 participants

Optimizing Surgical Decisions in Young Adults With Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2024-03-13

Completion:

2027-05-01

Conditions

• Breast Cancer Stage 0
• Breast Cancer Stage I
• Breast Cancer Stage II
• Breast Cancer Stage III

Interventions

• OTHER

No Results Yet

NCT06269900 | RECRUITING | PHASE3

450 participants

Dexamethasone for Treating Severe Hospital-acquired Pneumonia in Critically Ill Patients With a Proinflammatory Phenotype

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2024-03-26

Completion:

2026-12-15

Conditions

• Hospital Acquired Pneumonia

Interventions

• DRUG

No Results Yet

NCT06264830 | COMPLETED | NA

40 participants

3D Visualization System in Highly Myopic Cataract Operation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2024-07-03

Completion:

2025-12-31

Conditions

• Cataract
• High Myopia

Interventions

• DEVICE
• PROCEDURE

No Results Yet

NCT06257121 | NOT_YET_RECRUITING | NA

15 participants

Comparing Radiotherapy Immobilization Systems for Anxious HNC Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2026-10-15

Completion:

2028-09-01

Conditions

• Head and Neck Cancer
• Claustrophobia
• Anxiety

Interventions

• DEVICE

No Results Yet

NCT06252532 | ENROLLING_BY_INVITATION | NA

50 participants

Causal Role of Top-Down Theta Oscillations in Prioritization

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2024-07-01

Completion:

2027-01-31

Conditions

• Working Memory
• Epilepsy

Interventions

• DEVICE

No Results Yet

NCT06246916 | RECRUITING | PHASE3

560 participants

A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2024-09-09

Completion:

2027-03-22

Conditions

• Melanoma

Interventions

• DRUG

No Results Yet

NCT06238128 | COMPLETED | NA

773 participants

Opioid Rapid Response System: Naloxone Training in Communities

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2024-05-24

Completion:

2025-12-29

Conditions

• Opioid Overdose

Interventions

• BEHAVIORAL

Results Available

NCT06237335 | ACTIVE_NOT_RECRUITING | PHASE2

128 participants

A Phase 2 Study Evaluating Safety and Tolerability of RCT2100 (CFTR mRNA) in Healthy Participants and in Participants With CF

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2024-02-01

Completion:

2026-11-30

Conditions

• Cystic Fibrosis

Interventions

• DRUG
• OTHER

No Results Yet

NCT06226051 | RECRUITING

120 participants

Growing Little PEAPODS Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-19

Start Date:

2024-09-04

Completion:

2028-01-31

Conditions

• Premature Birth
• Premature Infant
• Premature
• Intrauterine Growth Restriction
• Small for Gestational Age at Delivery

Interventions

• DEVICE

No Results Yet

NCT06216964 | COMPLETED | NA

140 participants

Time to Clearance of Chlamydia Trachomatis and Neisseria Gonorrhoeae RNA After Treatment: a Prospective Cohort Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2024-04-05

Completion:

2026-06-01

Conditions

• Chlamydia Trachomatis
• Neisseria Gonorrhoeae
• Uncomplicated Infections

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT06207487 | COMPLETED

150 participants

Clinical and Economic Impact of Herpes Zoster in Cancer Patients

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-19

Start Date:

2019-09-01

Completion:

2024-12-30

Conditions

• Herpes Zoster

Interventions

• OTHER

No Results Yet

NCT06202183 | RECRUITING | NA

84 participants

Exercise for Gut Microbiome in Patients With Young-Onset Colorectal Cancer Undergoing Chemotherapy: The COURAGE Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2024-07-22

Completion:

2027-07-31

Conditions

• Colorectal Cancer
• Metastatic Colon Cancer
• Metastatic Colorectal Cancer

Interventions

• BEHAVIORAL

No Results Yet

NCT06194448 | ACTIVE_NOT_RECRUITING | PHASE2

76 participants

To Evaluate the Efficacy/Safety of Osimertinib Prior to CRT and Maintenance of it With Stage III, Unresectable NSCLC With EGFR Mutations

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2024-04-21

Completion:

2026-07-07

Conditions

• Lung Cancer

Interventions

• DRUG

No Results Yet

NCT06182293 | RECRUITING | NA

30 participants

Periodontal Microbiota in Systemic Sclerosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2024-10-24

Completion:

2027-10-24

Conditions

• Scleroderma Systemic

Interventions

• OTHER

No Results Yet

NCT06169267 | ACTIVE_NOT_RECRUITING | PHASE3

113 participants

Passive Music Intervention for the Reduction of Anxiety in Patients Undergoing Bone Marrow Aspiration and/or Biopsy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2024-04-22

Completion:

2026-10-01

Conditions

• Hematopoietic and Lymphoid System Neoplasm

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT06165250 | COMPLETED | PHASE3

151 participants

A Study to Evaluate the Efficacy and Safety of Co-administrated BR1018B and BR1018C

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2024-04-17

Completion:

2025-11-11

Conditions

• Essential Hypertension
• Primary Hypercholesterolemia

Interventions

• DRUG

No Results Yet

NCT06162741 | RECRUITING | NA

300 participants

Type I Hybrid Effectiveness-Implementation Trial of Primary Care Brief Mindfulness Training for Veterans

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2024-08-19

Completion:

2027-07-01

Conditions

• Post Traumatic Stress Disorder (PTSD)
• Depression
• Anxiety

Interventions

• BEHAVIORAL

No Results Yet

NCT06156254 | ACTIVE_NOT_RECRUITING | NA

800 participants

Community Care Intervention to Decrease COVID-19 Vaccination Inequities

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2023-09-21

Completion:

2026-03-21

Conditions

• COVID-19 Vaccination

Interventions

• BEHAVIORAL

No Results Yet

NCT06153836 | RECRUITING | PHASE2

45 participants

Neurotization of the Nipple Areolar Complex to Restore Sensation for Patients With Breast Cancer Undergoing Nipple Sparing Mastectomy and Reconstruction

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2023-12-05

Completion:

2026-11-10

Conditions

• Anatomic Stage 0 Breast Cancer AJCC v8
• Anatomic Stage I Breast Cancer AJCC v8
• Anatomic Stage IIA Breast Cancer AJCC v8

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT06150417 | RECRUITING | PHASE2

200 participants

MDRT in Prostate Cancer Treated With Long-term Androgen Deprivation Therapy in the STAMPEDE Trial (METANOVA)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2024-07-01

Completion:

2028-12-01

Conditions

• Prostate Cancer
• Malignant Neoplasm of Prostate
• Secondary Malignant Neoplasm of Prostate

Interventions

• DRUG
• OTHER
• RADIATION

No Results Yet

NCT06145763 | RECRUITING | NA

776 participants

A Digital Smoking Cessation Intervention for Helping American Indians and Alaska Natives Quit Smoking, IndigeQuit Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2025-07-03

Completion:

2027-11-30

Conditions

• Cigarette Smoking-Related Carcinoma

Interventions

• PROCEDURE
• BEHAVIORAL
• OTHER

No Results Yet