Clinical and Economic Impact of Herpes Zoster in Cancer Patients
NCT06207487 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 150
Last updated 2026-08-19
Summary
Herpes zoster (HZ) is an important infectious complication among patients with cancer, particularly in the setting of treatment-related immunosuppression. This retrospective observational cohort study aimed to characterize the clinical profile of HZ episodes and estimate direct hospital costs associated with emergency department visits and hospitalizations in patients with active malignancy treated at a Brazilian tertiary cancer center. The study also explored associations between cancer characteristics, recent oncologic therapies, and clinical outcomes, including postherpetic neuralgia, recurrence, disease dissemination, and hospital costs. Findings are intended to support future budget impact and cost-effectiveness analyses of herpes zoster vaccination in oncology populations.
Conditions
Interventions
- OTHER
-
Herpes Zoster episode
Clinically confirmed herpes zoster episode (initial episode or recurrence) identified through electronic medical records.
Sponsors & Collaborators
-
AC Camargo Cancer Center
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-09-01
- Primary Completion
- 2024-12-30
- Completion
- 2024-12-30
Countries
- Brazil
Study Locations
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