Clinical Trials Updated in 2026

NCT06483646 | COMPLETED | NA

100 participants

Evaluation of the Stability of Sulfur Volatile Compounds From Exhaled Air for Halitosis Diagnosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2024-10-01
Completion:: 2026-08-01

Conditions

Halitosis

Interventions

OTHER

No Results Yet

NCT06481033 | COMPLETED | NA

16 participants

Suicide Specific Rumination in Veterans

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2024-08-01
Completion:: 2026-03-17

Conditions

Depression
Suicide
Mood Disorders

Interventions

BEHAVIORAL

No Results Yet

NCT06477653 | RECRUITING | PHASE2

30 participants

Dupilumab as Add-On Therapy for Hypereosinophilic Syndrome With Partial Clinical Response to Eosinophil-Depleting Biologic Agents

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-02-05
Completion:: 2026-12-30

Conditions

Hypereosinophilic Syndrome

Interventions

BIOLOGICAL

No Results Yet

NCT06467357 | RECRUITING | PHASE3

620 participants

Phase 3 Study of T-DXd and Rilvegostomig Versus SoC in Advanced HER2-expressing Biliary Tract Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2024-08-12
Completion:: 2028-06-12

Conditions

Biliary Tract Cancer

Interventions

DRUG

No Results Yet

NCT06467214 | RECRUITING | NA

264 participants

Increasing Veterans' Social Engagement and Connectedness

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2024-10-04
Completion:: 2028-06-30

Conditions

Social Isolation

Interventions

BEHAVIORAL

No Results Yet

NCT06465810 | RECRUITING

1850 participants

Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-19
Start Date:: 2024-06-25
Completion:: 2031-12-29

Conditions

Transthyretin Amyloidosis
ATTR-CM
ATTRv-PN
ATTR
ATTR-Mixed
hATTR

Interventions

DRUG

No Results Yet

NCT06445959 | RECRUITING | PHASE1/PHASE2

78 participants

Phase 1b/2 Study of Decitabine and Venetoclax in Combination With the Targeted Mutant IDH1 Inhibitor Olutasidenib

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2024-08-29
Completion:: 2027-06-30

Conditions

Mutant IDH1 Inhibitor Olutasidenib

Interventions

DRUG

No Results Yet

NCT06444347 | RECRUITING | NA

200 participants

Impact of Biosynthetic Mesh on Paraesophageal Hernia Repair

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2024-06-10
Completion:: 2027-07-31

Conditions

Hiatal Hernia

Interventions

DEVICE
PROCEDURE

No Results Yet

NCT06439082 | RECRUITING | PHASE3

354 participants

A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2024-10-24
Completion:: 2029-07-02

Conditions

Sickle Cell Disease

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06430684 | RECRUITING | EARLY_PHASE1

40 participants

Feasibility Trial of Sodium-GLucose coTransporter 2 INhibitors in Pediatric Chronic KIDney DiSease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2024-08-23
Completion:: 2026-09-01

Conditions

Chronic Kidney Diseases
Pediatric Kidney Disease

Interventions

DRUG

No Results Yet

NCT06425549 | ACTIVE_NOT_RECRUITING | PHASE3

176 participants

A Study to Evaluate the Efficacy and Safety of Bimekizumab Compared to Ustekinumab in Children and Adolescents From 6 Years to Less Than 18 Years of Age With Moderate to Severe Plaque Psoriasis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2024-06-25
Completion:: 2028-08-21

Conditions

Moderate to Severe Plaque Psoriasis

Interventions

DRUG

No Results Yet

NCT06402383 | ACTIVE_NOT_RECRUITING | NA

2000 participants

Supporting the National Expansion of HPV-based Cervical Cancer Screening in Tanzania Among Women Living With HIV

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2024-05-25
Completion:: 2027-01-31

Conditions

Cervical Cancer

Interventions

BIOLOGICAL

No Results Yet

NCT06399640 | RECRUITING | PHASE1

60 participants

Eltanexor and Venetoclax in Relapsed or Refractory Myelodysplastic Syndrome and Acute Myeloid Leukemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2024-08-14
Completion:: 2027-02-01

Conditions

Relapsed Myelodysplastic Syndrome
Refractory Myelodysplastic Syndrome
Acute Myeloid Leukemia
Recurrent Acute Myeloid Leukemia
Refractory Acute Myeloid Leukemia

Interventions

DRUG
PROCEDURE

No Results Yet

NCT06395883 | RECRUITING

160 participants

Dynamics in Bone Turnover Markers During and After Short-term Glucocorticoid Treatment in Patients With an Inflammatory Joint Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-01-01
Completion:: 2027-10-31

Conditions

Osteoporosis
Osteoporosis, Steroid Induced
Inflammatory Rheumatism

Interventions

DRUG

No Results Yet

NCT06392711 | RECRUITING | PHASE1

36 participants

Dose-Escalation Trial of Mesenchymal Stromal Cells in Patients With Medical Xerostomia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2024-10-04
Completion:: 2028-11-30

Conditions

Xerostomia
Graft-versus-host-disease
Sjogren's Disease

Interventions

BIOLOGICAL

No Results Yet

NCT06365645 | COMPLETED | NA

90 participants

Feasibility & Acceptability of App-based Cognitive Behavioral Therapy for Postpartum Depression Prevention

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2024-06-07
Completion:: 2025-06-14

Conditions

Postpartum Depression
Postpartum Anxiety
Stress

Interventions

BEHAVIORAL

No Results Yet

NCT06359249 | ACTIVE_NOT_RECRUITING | NA

45 participants

Do the Symptoms of Chronic Constipation Improve With a Primary Care Programme Based on Behavioural Re-education and Abdominal Massage?

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2024-03-01
Completion:: 2026-12-28

Conditions

Constipation Chronic Idiopathic

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT06329661 | COMPLETED | PHASE4

204 participants

A Clinical Trial to Evaluate the Corneal Endothelial Health of DED Subjects Treated With Cyclosporine

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2024-04-22
Completion:: 2025-07-30

Conditions

Dry Eye Disease
Endothelial Cell

Interventions

DRUG

Results Available

NCT06326645 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

6 participants

Open-Label Pilot Study With Crofelemer in Patients With Short Bowel Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-03-03
Completion:: 2026-10-01

Conditions

Short Bowel Syndrome

Interventions

DRUG

No Results Yet

NCT06309472 | COMPLETED | PHASE2

76 participants

Trial of Mirtazapine for Depression in IBD

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2024-05-07
Completion:: 2025-10-03

Conditions

Major Depressive Disorder
Inflammatory Bowel Diseases

Interventions

DRUG

No Results Yet

NCT06298734 | RECRUITING | NA

40 participants

High-Intensity Exercise and High-Fiber Diet for Immunotherapy Outcomes in Melanoma Patients: The DUO Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2024-07-01
Completion:: 2027-07-31

Conditions

Melanoma (Skin)
Skin Cancer
Advanced Melanoma

Interventions

BEHAVIORAL

No Results Yet

NCT06275126 | RECRUITING | NA

800 participants

Optimizing Surgical Decisions in Young Adults With Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2024-03-13
Completion:: 2027-05-01

Conditions

Breast Cancer Stage 0
Breast Cancer Stage I
Breast Cancer Stage II
Breast Cancer Stage III

Interventions

OTHER

No Results Yet

NCT06269900 | RECRUITING | PHASE3

450 participants

Dexamethasone for Treating Severe Hospital-acquired Pneumonia in Critically Ill Patients With a Proinflammatory Phenotype

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2024-03-26
Completion:: 2026-12-15

Conditions

Hospital Acquired Pneumonia

Interventions

DRUG

No Results Yet

NCT06264830 | COMPLETED | NA

40 participants

3D Visualization System in Highly Myopic Cataract Operation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2024-07-03
Completion:: 2025-12-31

Conditions

Cataract
High Myopia

Interventions

DEVICE
PROCEDURE

No Results Yet

NCT06257121 | NOT_YET_RECRUITING | NA

15 participants

Comparing Radiotherapy Immobilization Systems for Anxious HNC Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2026-10-15
Completion:: 2028-09-01

Conditions

Head and Neck Cancer
Claustrophobia
Anxiety

Interventions

DEVICE

No Results Yet

NCT06252532 | ENROLLING_BY_INVITATION | NA

50 participants

Causal Role of Top-Down Theta Oscillations in Prioritization

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2024-07-01
Completion:: 2027-01-31

Conditions

Working Memory
Epilepsy

Interventions

DEVICE

No Results Yet

NCT06246916 | RECRUITING | PHASE3

560 participants

A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2024-09-09
Completion:: 2027-03-22

Conditions

Melanoma

Interventions

DRUG

No Results Yet

NCT06238128 | COMPLETED | NA

773 participants

Opioid Rapid Response System: Naloxone Training in Communities

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2024-05-24
Completion:: 2025-12-29

Conditions

Opioid Overdose

Interventions

BEHAVIORAL

Results Available

NCT06237335 | ACTIVE_NOT_RECRUITING | PHASE2

128 participants

A Phase 2 Study Evaluating Safety and Tolerability of RCT2100 (CFTR mRNA) in Healthy Participants and in Participants With CF

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2024-02-01
Completion:: 2026-11-30

Conditions

Cystic Fibrosis

Interventions

DRUG
OTHER

No Results Yet

NCT06226051 | RECRUITING

120 participants

Growing Little PEAPODS Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-19
Start Date:: 2024-09-04
Completion:: 2028-01-31

Conditions

Premature Birth
Premature Infant
Premature
Intrauterine Growth Restriction
Small for Gestational Age at Delivery

Interventions

DEVICE

No Results Yet

NCT06216964 | COMPLETED | NA

140 participants

Time to Clearance of Chlamydia Trachomatis and Neisseria Gonorrhoeae RNA After Treatment: a Prospective Cohort Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2024-04-05
Completion:: 2026-06-01

Conditions

Chlamydia Trachomatis
Neisseria Gonorrhoeae
Uncomplicated Infections

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06207487 | COMPLETED

150 participants

Clinical and Economic Impact of Herpes Zoster in Cancer Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-19
Start Date:: 2019-09-01
Completion:: 2024-12-30

Conditions

Herpes Zoster

Interventions

OTHER

No Results Yet

NCT06202183 | RECRUITING | NA

84 participants

Exercise for Gut Microbiome in Patients With Young-Onset Colorectal Cancer Undergoing Chemotherapy: The COURAGE Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2024-07-22
Completion:: 2027-07-31

Conditions

Colorectal Cancer
Metastatic Colon Cancer
Metastatic Colorectal Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT06194448 | ACTIVE_NOT_RECRUITING | PHASE2

76 participants

To Evaluate the Efficacy/Safety of Osimertinib Prior to CRT and Maintenance of it With Stage III, Unresectable NSCLC With EGFR Mutations

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2024-04-21
Completion:: 2026-07-07

Conditions

Lung Cancer

Interventions

DRUG

No Results Yet

NCT06182293 | RECRUITING | NA

30 participants

Periodontal Microbiota in Systemic Sclerosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2024-10-24
Completion:: 2027-10-24

Conditions

Scleroderma Systemic

Interventions

OTHER

No Results Yet

NCT06169267 | ACTIVE_NOT_RECRUITING | PHASE3

113 participants

Passive Music Intervention for the Reduction of Anxiety in Patients Undergoing Bone Marrow Aspiration and/or Biopsy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2024-04-22
Completion:: 2026-10-01

Conditions

Hematopoietic and Lymphoid System Neoplasm

Interventions

PROCEDURE
OTHER

No Results Yet

NCT06165250 | COMPLETED | PHASE3

151 participants

A Study to Evaluate the Efficacy and Safety of Co-administrated BR1018B and BR1018C

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2024-04-17
Completion:: 2025-11-11

Conditions

Essential Hypertension
Primary Hypercholesterolemia

Interventions

DRUG

No Results Yet

NCT06162741 | RECRUITING | NA

300 participants

Type I Hybrid Effectiveness-Implementation Trial of Primary Care Brief Mindfulness Training for Veterans

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2024-08-19
Completion:: 2027-07-01

Conditions

Post Traumatic Stress Disorder (PTSD)
Depression
Anxiety

Interventions

BEHAVIORAL

No Results Yet

NCT06156254 | ACTIVE_NOT_RECRUITING | NA

800 participants

Community Care Intervention to Decrease COVID-19 Vaccination Inequities

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2023-09-21
Completion:: 2026-03-21

Conditions

COVID-19 Vaccination

Interventions

BEHAVIORAL

No Results Yet

NCT06153836 | RECRUITING | PHASE2

45 participants

Neurotization of the Nipple Areolar Complex to Restore Sensation for Patients With Breast Cancer Undergoing Nipple Sparing Mastectomy and Reconstruction

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2023-12-05
Completion:: 2026-11-10

Conditions

Anatomic Stage 0 Breast Cancer AJCC v8
Anatomic Stage I Breast Cancer AJCC v8
Anatomic Stage IIA Breast Cancer AJCC v8

Interventions

PROCEDURE
OTHER

No Results Yet