Clinical Trials

NCT06850402 | RECRUITING | NA

400 participants

Evaluation of a Novel Optical Microscope With a Deep Depth of Field (DeepDOF) to Provide Histologic-quality Images on Cervical Biopsies and Loop Electrosurgical Excision Procedure (LEEP) Specimens at the Point-of-care

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-09-22

Completion:

2027-09-01

Conditions

• Cervical Cancer
• HIV

Interventions

• DEVICE

No Results Yet

NCT06846996 | RECRUITING

260 participants

Real-world Effectiveness and Safety of Trastuzumab Deruxtecan in Patients With Locally Advanced or Metastatic HER2-positive Gastric or Gastroesophageal Junction Adenocarcinoma in China

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2025-02-27

Completion:

2027-07-31

Conditions

• HER2-positive Gastric Cancer
• HER2-positive Gastroesophageal Junction

Interventions

• DRUG

No Results Yet

NCT06841796 | ACTIVE_NOT_RECRUITING | NA

84 participants

The YMCA Healthy Lifestyle Program for Prediabetes

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-02-17

Completion:

2026-10-31

Conditions

• PreDiabetes

Interventions

• DEVICE

No Results Yet

NCT06835829 | ACTIVE_NOT_RECRUITING | NA

480 participants

Comparing Advanced Hemostasis and Ultrasound-Guided Puncture to Conventional Approaches in Distal Radial Access

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-12-31

Completion:

2026-07-30

Conditions

• Coronary Catheterization

Interventions

• DEVICE
• PROCEDURE

No Results Yet

NCT06826079 | RECRUITING | PHASE2

86 participants

Safety and Efficacy Study of Sorbitol With Neoadjuvant Chemotherapy Combined With Tirellizumab (PD-1 Inhibitor) in Patients With Locally Advanced Gastric Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2024-11-01

Completion:

2028-08-01

Conditions

• Gastric Junction Adenocarcinoma
• Gastric Cancer
• Immunotherapy
• Neoadjuvant Therapies

Interventions

• DRUG

No Results Yet

NCT06822049 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

200 participants

Remote vs. In-Person Study Evaluation (RISE) Trials: RISE Above Smoking (Trial 1)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-03-10

Completion:

2026-08-31

Conditions

• Remote vs. In-Person
• Remote Visits
• In-person Visits

Interventions

• DRUG

No Results Yet

NCT06810934 | RECRUITING | PHASE1/PHASE2

80 participants

A Phase 1/2A, Randomized Study of a T Follicular Helper (TFH)-Targeting Genetic Vaccine Strategy Designed to Induce Broad, Durable Immune Responses

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-10-21

Completion:

2027-12-31

Conditions

• COVID-19
• SARS-CoV-2 Infection

Interventions

• BIOLOGICAL

No Results Yet

NCT06809764 | RECRUITING

150 participants

Clinical Effectiveness and Safety of Trastuzumab Deruxtecan (T-DXd) in Chinese Patients With HER2m NSCLC (RERUN)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2025-02-21

Completion:

2027-02-12

Conditions

• Non-small Cell Lung Cancer

Interventions

• OTHER

No Results Yet

NCT06804928 | COMPLETED | NA

70 participants

Effect of Virtual Reality Glasses on Pain, Anxiety, and Comfort During Extracorporeal Shock Wave Lithotripsy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-02-01

Completion:

2025-09-01

Conditions

• ESWL
• Anxiety
• Pain
• Comfort
• Virtual Reality

Interventions

• BEHAVIORAL

No Results Yet

NCT06804200 | ACTIVE_NOT_RECRUITING

800 participants

Prospective Validation of AKI Prediction

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2025-06-25

Completion:

2026-08-01

Conditions

• Acute Kidney Injury

No Results Yet

NCT06799065 | RECRUITING | PHASE1

90 participants

First-in-Human Study of ATX-295, an Oral Inhibitor of KIF18A, in Patients With Advanced or Metastatic Solid Tumors, Including Ovarian Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-03-21

Completion:

2027-04-30

Conditions

• Advanced Solid Tumors
• Breast Cancer Recurrent
• Ovarian Cancer
• High-grade Serous Ovarian Carcinoma
• Triple Negative Breast Cancer

Interventions

• DRUG

No Results Yet

NCT06798142 | ACTIVE_NOT_RECRUITING

193 participants

Risk Stratification and Heterogeneity for Organ Damage in Acute Diquat Poisoning

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2022-02-01

Completion:

2024-09-30

Conditions

• Toxic Encephalopathy
• Diquat Poisoning

Interventions

• PROCEDURE

No Results Yet

NCT06795581 | RECRUITING | PHASE1

30 participants

PET Imaging of Phosphodiesterase-4B (PDE4B) in Alcohol Use Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-03-20

Completion:

2028-12-11

Conditions

• Alcohol Use Disorder

Interventions

• DRUG

No Results Yet

NCT06792695 | RECRUITING | PHASE2

80 participants

A Study of Novel Study Interventions and Combinations in Participants With Colorectal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-03-12

Completion:

2027-06-30

Conditions

• Metastatic Colorectal Cancer

Interventions

• DRUG

No Results Yet

NCT06789653 | RECRUITING

80 participants

A Novel Approach Utilizing Organ Specific Age Proteomics

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2024-10-10

Completion:

2027-11-01

Conditions

• Breast Cancer

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT06769464 | RECRUITING | NA

28 participants

Electrophysiological Representations of Odor in the Human Brain Study 1

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2024-04-01

Completion:

2027-04-01

Conditions

• Odor Intensity Ratings

Interventions

• BEHAVIORAL

No Results Yet

NCT06765551 | COMPLETED

64 participants

AI Based Muscular Ultrasound to Assess Intensive Care Unit-acquired Weakness

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2024-10-01

Completion:

2026-07-31

Conditions

• Intensive Care Unit-acquired Weakness
• Artifical Intelligence
• Ultrasound

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT06764485 | RECRUITING | PHASE3

960 participants

A Study to Compare the Efficacy and Safety of BMS-986365 Versus the Investigator's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-03-13

Completion:

2027-09-12

Conditions

• Metastatic Castration-resistant Prostate Cancer

Interventions

• DRUG

No Results Yet

NCT06764316 | RECRUITING | PHASE1

148 participants

A First-in-human Study to Learn About the Safety of BAY 3547926 and How Well it Works in Participants With Advanced Liver Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-02-28

Completion:

2029-07-31

Conditions

• Hepatocellular Carcinoma

Interventions

• DRUG

No Results Yet

NCT06756607 | RECRUITING | NA

500 participants

The ECOG-ACRIN SUPPORT Trial: Multilevel Intervention to Improve Diverse Enrollment in Cancer Clinical Trials

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-04-25

Completion:

2027-08-01

Conditions

• Cancer

Interventions

• OTHER

No Results Yet

NCT06753097 | COMPLETED | NA

930 participants

Continuous Finger-cuff Arterial Pressure Monitoring and Intraoperative Hypotension During Non-cardiac Surgery: the Randomized DETECT II Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-01-06

Completion:

2026-02-19

Conditions

• Intraoperative Hypotension

Interventions

• DEVICE

No Results Yet

NCT06743958 | ACTIVE_NOT_RECRUITING | NA

16 participants

Prehabilitation in Childhood Soft Tissue or Bone Sarcomas

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-02-20

Completion:

2027-10-30

Conditions

• Soft Tissue Sarcoma of the Lower Extremity
• Bone Tumor of the Lower Extremity
• Childhood and Adolescent Cancer

Interventions

• OTHER

No Results Yet

NCT06743776 | NO_LONGER_AVAILABLE

Scalable Expanded Access With Analysis of Neurofilament and Other Biomarkers for Ibudilast in ALS

Study Type:

EXPANDED_ACCESS

Last Updated:

2026-08-18

Conditions

• ALS

Interventions

• DRUG

No Results Yet

NCT06743126 | RECRUITING | PHASE3

360 participants

SUPRAME-ACTengine® IMA203 vs. Investigator's Choice of Treatment in Previously Treated, Unresectable or Metastatic Cutaneous Melanoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-01-14

Completion:

2028-01-31

Conditions

• Melanoma, Cutaneous Malignant

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT06740981 | COMPLETED

126 participants

Nutritional Intake in Patients on Noninvasive Ventilation: a Prospective Observational Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2024-12-16

Completion:

2026-04-27

Conditions

• Malnutrition or Risk of Malnutrition
• Acute Respiratory Failure

Interventions

• OTHER

No Results Yet

NCT06737172 | ACTIVE_NOT_RECRUITING

18 participants

Functional and Structural Outcomes Following Childhood Bone or Soft Tissue Sarcomas of the Lower Extremity

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2025-04-01

Completion:

2026-10-31

Conditions

• Soft Tissue Sarcoma of the Lower Extremity
• Bone Sarcoma of the Lower Extremity
• Childhood and Adolescent Cancer

No Results Yet

NCT06733441 | ACTIVE_NOT_RECRUITING | PHASE1

50 participants

A Study of TLN-254 in Participants With Relapsed or Refractory T-cell Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2024-12-16

Completion:

2026-11-15

Conditions

• Lymphoma

Interventions

• DRUG

No Results Yet

NCT06731907 | RECRUITING | PHASE2

90 participants

A Study of Pembrolizumab With or Without Chemotherapy in Combination With Additional Treatments for Advanced Non-Small Cell Lung Cancer (NSCLC) (MK-3475-01G/KEYMAKER U01)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-03-30

Completion:

2032-03-12

Conditions

• Non-small Cell Lung Cancer

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT06728072 | RECRUITING | PHASE2

97 participants

Addition of Antibiotics to Upfront Treatment Regimen for Colorectal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-03-07

Completion:

2035-07-01

Conditions

• Colorectal Cancer
• CRC

Interventions

• DRUG

No Results Yet

NCT06720090 | RECRUITING | EARLY_PHASE1

40 participants

Light Therapy for Obsessive-compulsive Disorder (OCD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2024-12-16

Completion:

2029-03-31

Conditions

• OCD

Interventions

• BEHAVIORAL

No Results Yet

NCT06717178 | COMPLETED

360 participants

Cancer and Aging Research Group (CARG) Chemotherapy Toxicity Risk Scores in Older Adults With Cancer in China

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2024-12-24

Completion:

2025-12-31

Conditions

• Cancer
• Cancer-related Problem/Condition

Interventions

• DRUG

No Results Yet

NCT06702592 | NOT_YET_RECRUITING | NA

360 participants

Virtual Testis Cancer Lay Support and Survivorship Aim 2

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2026-09-30

Completion:

2028-06-30

Conditions

• Testicular Cancer
• Testis Cancer

Interventions

• BEHAVIORAL

No Results Yet

NCT06700538 | RECRUITING | PHASE1/PHASE2

180 participants

A First-In-Human Study of ARO-INHBE in Adults With Obesity With and Without Type 2 Diabetes Mellitus

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2024-12-04

Completion:

2027-09-17

Conditions

• Obesity

Interventions

• DRUG

No Results Yet

NCT06691035 | ACTIVE_NOT_RECRUITING | PHASE1

18 participants

Immunologic Targeting of ESR1 Receptor for Hormone Receptor Expressing Metastatic Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2024-11-04

Completion:

2026-11-30

Conditions

• Breast Cancer Metastatic Breast Cancer
• HER2-negative Breast Cancer

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT06685796 | COMPLETED | PHASE2

65 participants

A Study of BEBT-209 in Combination With Chemotherapy for the Treatment of Advanced Triple-Negative Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2023-04-12

Completion:

2026-04-20

Conditions

• Advanced Triple-Negative Breast Cancer

Interventions

• DRUG

No Results Yet

NCT06675903 | RECRUITING

54 participants

Continuous Glucose Monitoring (CGM) After Kidney Transplantation

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2024-11-12

Completion:

2027-01-01

Conditions

• Hyperglycaemia
• Kidney Transplantation

No Results Yet

NCT06667037 | ACTIVE_NOT_RECRUITING | NA

112 participants

Orthokeratology and 0.01% Atropine Sequential Treatment for Myopia Control

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2024-09-21

Completion:

2026-12-31

Conditions

• Myopia

Interventions

• DEVICE
• DRUG

No Results Yet

NCT06666673 | RECRUITING | EARLY_PHASE1

64 participants

Effect of Neural Constraints on Movement in Stroke

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2024-08-23

Completion:

2029-06-30

Conditions

• Stroke

Interventions

• DRUG

No Results Yet

NCT06660017 | NOT_YET_RECRUITING | PHASE2

62 participants

Head and Neck Cancer Patients With Oral Mucositis Treated With Ketamine Oral Rinse

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2026-09-30

Completion:

2027-06-30

Conditions

• Head and Neck Cancer

Interventions

• DRUG

No Results Yet

NCT06656494 | RECRUITING | PHASE1

266 participants

ICP-248 in Combination With Azacitidine for the Treatment in Patients With Myeloid Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2024-12-18

Completion:

2027-06-30

Conditions

• Acute Myelogenous Leukemia
• Myelodysplastic Syndromes (MDS)

Interventions

• DRUG

No Results Yet