Clinical Trials

NCT05736848 | ACTIVE_NOT_RECRUITING

200 participants

A Retrospective Assessment of OviTex PRS (OviTex)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2022-09-27

Completion:

2026-08-30

Conditions

• Reconstructive Surgical Procedures

Interventions

• DEVICE

No Results Yet

NCT05719441 | RECRUITING | PHASE2

48 participants

A Clinical Trial of Combination HIV-Specific Broadly Neutralizing Monoclonal Antibodies Combined With ART Initiation During Acute HIV Infection to Induce HIV Remission

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2024-08-19

Completion:

2028-04-06

Conditions

• Acute HIV Infection

Interventions

• BIOLOGICAL
• OTHER
• DRUG

No Results Yet

NCT05701215 | COMPLETED | PHASE2

10 participants

Venetoclax After TKI to Target Persisting Stem Cells in CML

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2023-08-31

Completion:

2026-05-31

Conditions

• Chronic Myeloid Leukemia

Interventions

• DRUG

No Results Yet

NCT05701176 | RECRUITING | NA

15 participants

A Clinical Imaging Study of the Changes in [18F]F-AraG Uptake Following Anti-PD-1 Therapy in Non-small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2022-11-03

Completion:

2027-01-31

Conditions

• Advanced Stage Non-small Cell Lung Cancer

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05690724 | COMPLETED | NA

100 participants

Exploratory Trial in Healthy Adults With Mild Cognitive Impairment,16-week Intervention With Mitocholine™

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2023-01-09

Completion:

2024-08-16

Conditions

• Mild Cognitive Impairment

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT05684796 | COMPLETED | NA

100 participants

Comparison of Two Pulmonary Embolism Treatments

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2023-11-27

Completion:

2025-06-12

Conditions

• Pulmonary Embolism Acute

Interventions

• DRUG
• DEVICE

Results Available

NCT05670496 | RECRUITING

600 participants

Collection of Clinical Data and Specimens for Research in Hearing, Balance, Taste, Smell, Voice, Speech, and Language Disorders.

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2023-03-08

Completion:

2027-08-01

Conditions

• Hearing Loss
• Deafness

No Results Yet

NCT05665595 | TERMINATED | PHASE3

1594 participants

A Study of Adjuvant Pembrolizumab/Vibostolimab (MK-7684A) Versus Pembrolizumab for Resected High-Risk Melanoma in Participants With High-Risk Stage II-IV Melanoma (MK-7684A-010/KEYVIBE-010)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2023-01-19

Completion:

2024-03-06

Conditions

• Melanoma

Interventions

• BIOLOGICAL

Results Available

NCT05657405 | RECRUITING

1250 participants

Observational Study of Advanced Data Analytics in Genetic Conditions

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2026-07-29

Completion:

2032-12-31

Conditions

• Genetic Conditions

No Results Yet

NCT05657106 | ACTIVE_NOT_RECRUITING | NA

752 participants

Kentucky Outreach Service Kiosk (KyOSK): Reducing HIV, HCV, and Overdose Risk

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2023-03-06

Completion:

2027-05-31

Conditions

• Opioid-Related Disorders
• Hepatitis C (HCV)
• Human Immunodeficiency Virus (HIV)
• Drug Overdose
• Substance Abuse
• Intravenous Drug Usage
• Opiate Substitution Treatment
• Sexually Transmitted Diseases

Interventions

• BEHAVIORAL

No Results Yet

NCT05653193 | ACTIVE_NOT_RECRUITING | PHASE2

50 participants

Interferon-gamma as Adjunctive Therapy in Chronic Pulmonary Aspergillosis: a Randomised Feasibility Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2024-05-17

Completion:

2026-11-30

Conditions

• Chronic Pulmonary Aspergillosis
• Aspergillosis

Interventions

• DRUG

No Results Yet

NCT05651932 | RECRUITING | PHASE1

165 participants

A Study of an MMSET Inhibitor in Patients With Relapsed and Refractory Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2023-02-22

Completion:

2027-12-31

Conditions

• Multiple Myeloma
• Myeloma
• Myeloma Multiple

Interventions

• DRUG

No Results Yet

NCT05645328 | ACTIVE_NOT_RECRUITING | NA

31 participants

Implementation of a Health System Intervention to Improve Quality of Cancer Care for Rural Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2023-01-20

Completion:

2026-12-31

Conditions

• Cancer

Interventions

• OTHER

No Results Yet

NCT05621668 | ACTIVE_NOT_RECRUITING | PHASE1

5 participants

A First-In-Human Phase 1 Trial of T-Cell Membrane-Anchored Tumor Targeted Il12 (Attil12)- T-Cell Therapy in Subjects With Advanced/Metastatic Soft Tissue and Bone Sarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2023-09-08

Completion:

2027-09-30

Conditions

• Soft Tissue Sarcoma
• Bone Sarcoma

Interventions

• DRUG

No Results Yet

NCT05604534 | RECRUITING

200 participants

Assessing and Improving Quantitative Magnetic Resonance Imaging Metrics in Human Subjects

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2023-02-02

Completion:

2041-03-31

Conditions

• Normal Physiology

No Results Yet

NCT05587023 | COMPLETED | NA

62 participants

Effect of Ultrasound-guided Left Stellate Ganglion Block on Rapid Recovery of Patients Undergoing Cardiac Valve Replacement and Its Mechanism

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2022-10-16

Completion:

2023-12-30

Conditions

• Stellate Ganglion Block
• Heart Valve Replacement (Mechanical or Biological With AF)

Interventions

• PROCEDURE

No Results Yet

NCT05586581 | RECRUITING | PHASE1/PHASE2

70 participants

SV2A & TSPO PET Imaging Measures to Reveal Mechanisms of HIV Neuropathogenesis During Antiretroviral Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2023-05-17

Completion:

2028-12-31

Conditions

• HIV Associated Neurocognitive Disorder
• HIV Dementia
• HIV Encephalitis
• Healthy

Interventions

• DRUG

No Results Yet

NCT05558514 | COMPLETED | NA

24 participants

Place-based Cochlear Implant Mapping

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2023-06-07

Completion:

2026-06-24

Conditions

• Hearing Loss, Sensorineural
• Cochlear Implants

Interventions

• OTHER

No Results Yet

NCT05541276 | RECRUITING | PHASE3

676 participants

MELAtonin for Prevention of Postoperative Agitation and Emergence Delirium in Children

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-01-21

Completion:

2027-03-01

Conditions

• Emergence Delirium

Interventions

• DRUG

No Results Yet

NCT05521854 | COMPLETED | NA

62 participants

Contingency Management for Drug Use: Does Age Matter?

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2023-05-01

Completion:

2026-05-26

Conditions

• Opioid Use Disorder
• Methamphetamine Abuse
• Cocaine Use Disorder

Interventions

• BEHAVIORAL

No Results Yet

NCT05471128 | ACTIVE_NOT_RECRUITING

29 participants

MRI Fusion Biopsy vs. Micro-Ultrasound Guided Biopsy

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2023-01-27

Completion:

2025-05-01

Conditions

• Prostate Cancer

Interventions

• PROCEDURE

No Results Yet

NCT05470504 | RECRUITING | PHASE2

25 participants

Study of Growth Hormone Inhibition Using Pegvisomant in Severe Insulin Resistance

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2023-01-23

Completion:

2028-01-30

Conditions

• Insulin Receptor Mutation
• Partial Lipodystrophy

Interventions

• DRUG

No Results Yet

NCT05435014 | TERMINATED | PHASE1/PHASE2

2 participants

T-ACE Oil by TAE/TACE in Patients With Hepatocellular Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2022-09-13

Completion:

2026-06-15

Conditions

• Hepatocellular Carcinoma

Interventions

• DRUG

No Results Yet

NCT05431088 | RECRUITING | PHASE2/PHASE3

389 participants

A Phase 2/3 Study of Osivelotor in Adult and Adolescent Participants With SCD

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2022-09-22

Completion:

2030-12-30

Conditions

• Sickle Cell Disease

Interventions

• DRUG

No Results Yet

NCT05426057 | RECRUITING | NA

468 participants

Mental Health in Primary Care

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2022-04-26

Completion:

2028-04-30

Conditions

• Depression, Anxiety
• Suicide
• Drug Use

Interventions

• BEHAVIORAL

No Results Yet

NCT05421741 | RECRUITING | PHASE4

242 participants

Prophylactic Antibiotic Coated Nail to Prevent Infection: A Clinical Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2023-05-15

Completion:

2026-12-31

Conditions

• Osteomyelitis Tibia
• Tibial Fractures
• Open Tibia Fracture

Interventions

• DRUG
• OTHER

No Results Yet

NCT05419037 | RECRUITING

90 participants

Natural History of Pregnancy and Pregnancy Outcomes in Metreleptin-Treated vs Untreated Subjects With Lipodystrophy

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2022-09-07

Completion:

2028-03-01

Conditions

• Lipodystrophy

No Results Yet

NCT05410977 | RECRUITING

950 participants

Collecting Blood and Stool Samples to Detect Colorectal Cancer or Advanced Neoplasia in Lynch Syndrome Patients

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2022-03-30

Completion:

2027-12-31

Conditions

• Colorectal Carcinoma
• Lynch Syndrome

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT05393154 | COMPLETED

55 participants

Pilot Study of Biopsy Scanner for Evaluation of Bronchoscopic Small Biopsy Specimens to Determine Adequacy

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2021-09-22

Completion:

2022-10-26

Conditions

• Lung Cancer

Interventions

• DEVICE

No Results Yet

NCT05307679 | TERMINATED | PHASE2

7 participants

A Study to Evaluate the Safety and Efficacy of Basmisanil Treatment in Children Aged 2-14 Years With Dup15q Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2022-12-16

Completion:

2024-03-04

Conditions

• Dup15q Syndrome

Interventions

• DRUG

Results Available

NCT05277688 | RECRUITING | PHASE3

340 participants

Adjuvant Concurrent Chemoradiotherapy Versus Radiotherapy in Early-stage Cervical Cancer Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2022-03-15

Completion:

2027-12-30

Conditions

• Cervical Cancer

Interventions

• DRUG
• RADIATION

No Results Yet

NCT05277116 | ACTIVE_NOT_RECRUITING | NA

26877 participants

The Electronic Medical Records and GEnomics (eMERGE) Network Genomic Risk Assessment

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2022-02-16

Completion:

2030-04-30

Conditions

• Genetic Disease

Interventions

• OTHER

No Results Yet

NCT05273567 | COMPLETED | PHASE2

22 participants

A Trial of Guanfacine-er for Cannabis Use Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2022-06-01

Completion:

2023-09-08

Conditions

• Cannabis Use

Interventions

• DRUG
• OTHER

Results Available

NCT05267951 | RECRUITING | NA

9 participants

Closed-loop Spinal Stimulation for Restoration of Upper Extremity Function After Spinal Cord Injury

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2022-10-12

Completion:

2027-12-31

Conditions

• Spinal Cord Injuries

Interventions

• DEVICE
• OTHER

No Results Yet

NCT05246514 | ACTIVE_NOT_RECRUITING | PHASE2

72 participants

A Single Arm Phase 2 Study to Evaluate Efficacy and Safety of Trastuzumab Deruxtecan for Patients With HER2 Mutant NSCLC

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2022-07-13

Completion:

2024-11-04

Conditions

• HER2-mutant Non-Small Cell Lung Cancer

Interventions

• DRUG

Results Available

NCT05227105 | ACTIVE_NOT_RECRUITING | NA

640 participants

PA Moves Trial - Patient Participants

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2023-05-23

Completion:

2027-08-31

Conditions

• Overweight or Obesity
• Diabetes Mellitus, Type 2
• Physical Inactivity

Interventions

• BEHAVIORAL

No Results Yet

NCT05215353 | RECRUITING | PHASE4

368 participants

A Study Comparing Music Therapy and Cognitive Behavioral Therapy for Anxiety in Cancer Survivors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2022-01-14

Completion:

2027-01-31

Conditions

• Survivorship

Interventions

• OTHER

No Results Yet

NCT05213676 | RECRUITING | PHASE4

600 participants

De-implementing Inhaled Nitric Oxide for Congenital Diaphragmatic Hernia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-11-01

Completion:

2030-10-31

Conditions

• Congenital Diaphragmatic Hernia

Interventions

• DRUG
• OTHER

No Results Yet

NCT05177510 | RECRUITING | PHASE2

400 participants

Mifepristone Outpatient Labour Induction

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2023-08-25

Completion:

2027-03-31

Conditions

• Labor, Induced

Interventions

• DRUG

No Results Yet

NCT05165940 | NOT_YET_RECRUITING | NA

40 participants

Facilitating Transition to Recommended PTSD Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2026-12-01

Completion:

2027-05-03

Conditions

• PTSD

Interventions

• BEHAVIORAL

No Results Yet