Clinical Trials

NCT05002660 | COMPLETED | NA

2420 participants

The Change Club Study: Evaluation of Civic Engagement for Built Environment Change and Health Improvement

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2023-05-03

Completion:

2026-04-23

Conditions

• Heart Diseases

Interventions

• BEHAVIORAL

No Results Yet

NCT04980222 | ACTIVE_NOT_RECRUITING | PHASE2

46 participants

A Study to Evaluate the Safety and Efficacy of Glofitamab in Combination With Rituximab (R) Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (CHOP) in Circulating Tumor (ct)DNA High-Risk Patients With Untreated Diffuse Large B-Cell Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2022-03-22

Completion:

2024-09-24

Conditions

• Lymphoma

Interventions

• DRUG

Results Available

NCT04957277 | ACTIVE_NOT_RECRUITING | NA

30 participants

Stepping to Understand Lower Limb Impairments in Bilateral Cerebral Palsy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2021-05-19

Completion:

2027-06-30

Conditions

• Cerebral Palsy
• Bilateral Cerebral Palsy
• Diplegic Cerebral Palsy

Interventions

• OTHER

No Results Yet

NCT04942834 | COMPLETED | NA

320 participants

Using Cryoballoon Ablation as Initial Treatment for Persistent Atrial Fibrillation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2021-10-01

Completion:

2025-08-23

Conditions

• Atrial Fibrillation, Persistent
• Arrhythmias, Cardiac

Interventions

• DRUG
• DEVICE

No Results Yet

NCT04929041 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

427 participants

Testing the Addition of Radiation Therapy to the Usual Treatment (Immunotherapy With or Without Chemotherapy) for Advanced Stage Non-small Cell Lung Cancer Patients Who Are PD-L1 Negative

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2022-10-07

Completion:

2030-12-12

Conditions

• Lung Adenocarcinoma
• Lung Adenosquamous Carcinoma
• Lung Non-Small Cell Carcinoma
• Stage IIIB Lung Cancer AJCC v8
• Stage IIIC Lung Cancer AJCC v8
• Stage IV Lung Cancer AJCC v8

Interventions

• PROCEDURE
• BIOLOGICAL
• OTHER
• RADIATION

No Results Yet

NCT04928508 | ACTIVE_NOT_RECRUITING | PHASE1

50 participants

Advanced or Recurrent Solid Tumors Treated With SHetA2

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2022-07-27

Completion:

2026-09-30

Conditions

• Solid Tumor, Adult

Interventions

• DRUG

No Results Yet

NCT04925492 | COMPLETED | PHASE1

15 participants

PET Imaging of Vaso-Occlusive Crisis (VOC) in SCD

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2022-11-11

Completion:

2026-03-11

Conditions

• Sickle Cell Disease

Interventions

• RADIATION
• DRUG

No Results Yet

NCT04903795 | RECRUITING | PHASE1

18 participants

BRiTE - Bispecific T Cell Engager for Patients With Glioblastoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2026-08-17

Completion:

2027-12-30

Conditions

• Newly Diagnosed Glioblastoma
• Recurrent Glioblastoma

Interventions

• DRUG

No Results Yet

NCT04880434 | COMPLETED | PHASE2

95 participants

Study of Brexucabtagene Autoleucel (KTE-X19) in Participants With Relapsed/Refractory Mantle Cell Lymphoma (Cohort 3)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2021-04-23

Completion:

2025-06-17

Conditions

• Relapsed/Refractory Mantle Cell Lymphoma

Interventions

• DRUG
• BIOLOGICAL

Results Available

NCT04859270 | RECRUITING

600 participants

The Holistic Health Care of Post-Cardiac Arrest Survivors: From Patient's Health to Family Resilience

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2021-04-12

Completion:

2027-01-31

Conditions

• Post-Cardiac Arrest Syndrome

No Results Yet

NCT04858724 | RECRUITING

2000 participants

The Chinese Registry of Prognostic Study of IgA Nephropathy (CRPIGA)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2020-12-01

Completion:

2027-12-30

Conditions

• IgA Nephropathy

No Results Yet

NCT04850287 | ACTIVE_NOT_RECRUITING | NA

2000000 participants

Improving Health Awareness Using Social Network Interventions

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2021-02-10

Completion:

2027-06-30

Conditions

• Health Knowledge, Attitudes, Practice

Interventions

• BEHAVIORAL

No Results Yet

NCT04841304 | COMPLETED

70 participants

Cardiac Arrhythmia in Patients With End-Stage Renal Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2021-06-01

Completion:

2024-04-01

Conditions

• End Stage Renal Disease on Dialysis
• Cardiac Arrhythmia
• Diabetes Mellitus
• Hypoglycemia

Interventions

• DEVICE

No Results Yet

NCT04815954 | ACTIVE_NOT_RECRUITING | NA

120 participants

Early vs Late Urinary Catheter Removal After Renal Transplantation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2019-03-26

Completion:

2027-03-26

Conditions

• Kidney Transplant; Complications
• Kidney Transplant Infection
• Urinary Fistula
• Urinary Tract Infections
• Urinary Catheter

Interventions

• PROCEDURE

No Results Yet

NCT04815564 | ACTIVE_NOT_RECRUITING | NA

57 participants

Clear Aligners for the Treatment of Dental Malocclusion in OI

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2022-08-01

Completion:

2027-08-01

Conditions

• Osteogenesis Imperfecta

Interventions

• DEVICE

No Results Yet

NCT04807764 | COMPLETED | NA

14 participants

Transspinal Stimulation Plus Locomotor Training for SCI

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2021-08-01

Completion:

2024-12-01

Conditions

• Spinal Cord Injuries
• Paraplegia, Spinal
• Tetraplegia/Tetraparesis
• Paraplegia, Spastic

Interventions

• COMBINATION_PRODUCT
• OTHER

Results Available

NCT04789746 | ENROLLING_BY_INVITATION | NA

25 participants

Ready, Set, Go! A Physical Fitness Intervention for Children With Mobility Challenges

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2019-02-20

Completion:

2027-12-31

Conditions

• Cerebral Palsy
• Myelomeningocele
• Arthrogryposis
• Motor Skills Disorders
• Gross Motor Development Delay

Interventions

• BEHAVIORAL

No Results Yet

NCT04772079 | RECRUITING | PHASE3

153 participants

A Study to Evaluate the Drug Levels, Efficacy and Safety of Deucravacitinib in Children and Adolescent Participants With Moderate to Severe Plaque Psoriasis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2021-03-23

Completion:

2029-01-01

Conditions

• Plaque Psoriasis

Interventions

• DRUG
• OTHER

No Results Yet

NCT04755634 | COMPLETED | NA

20 participants

Shafer Width and Girth: The Use of Injectable Fillers for Penile Enhancement

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2021-04-23

Completion:

2024-06-27

Conditions

• Micropenis

Interventions

• DEVICE

Results Available

NCT04744116 | RECRUITING | EARLY_PHASE1

24 participants

Addition of Cord Blood Tissue-Derived Mesenchymal Stromal Cells to Ruxolitinib for the Treatment of Steroid-Refractory Acute Graft Versus Host Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2021-02-17

Completion:

2032-03-31

Conditions

• Hematopoietic and Lymphoid Cell Neoplasm
• Steroid Refractory Graft Versus Host Disease

Interventions

• OTHER
• DRUG

No Results Yet

NCT04736238 | COMPLETED | NA

54 participants

Clinical Study on the Treatment of Chronic Instability of the Lateral Ankle Joint by Repairing the Anterior Talofibular Ligament Under Total Arthroscopy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2018-06-01

Completion:

2021-01-15

Conditions

• Anterior Talofibular Ligament Injury
• Ankle Sprains

Interventions

• PROCEDURE

No Results Yet

NCT04638647 | RECRUITING | PHASE4

1000 participants

Secukinumab Open Label Roll-over Extension Protocol

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2020-12-22

Completion:

2030-01-29

Conditions

• Autoimmunity, Inflammation

Interventions

• BIOLOGICAL

No Results Yet

NCT04606966 | COMPLETED | NA

236 participants

Physiological Mechanisms of Therapeutic Horseback Riding Intervention Effects in a Psychiatric Population of ASD Youth

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2020-12-22

Completion:

2025-02-22

Conditions

• Autism Spectrum Disorder
• Mental Disorders

Interventions

• OTHER

Results Available

NCT04605458 | COMPLETED | NA

282 participants

Contingency Management to Promote Smoking Abstinence in Cancer Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2020-11-25

Completion:

2025-07-10

Conditions

• Smoking Cessation

Interventions

• COMBINATION_PRODUCT

Results Available

NCT04598009 | RECRUITING | PHASE2

25 participants

Binimetinib and Imatinib for Unresectable Stage III-IV KIT-Mutant Melanoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2021-03-03

Completion:

2027-05-31

Conditions

• Melanoma Stage III
• Melanoma Stage IV

Interventions

• DRUG

No Results Yet

NCT04592029 | COMPLETED | PHASE1

36 participants

TACE Combined With Sintilimab and Bevacizumab for Unresectable HCC

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2020-10-21

Completion:

2023-02-07

Conditions

• Hepatocellular Carcinoma Non-resectable

Interventions

• DRUG

No Results Yet

NCT04590235 | ACTIVE_NOT_RECRUITING | PHASE1

32 participants

A Study of Selumetinib in Chinese Paediatric and Adult Subjects With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas (PN)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2020-12-16

Completion:

2022-08-16

Conditions

• Neurofibromatosis 1
• Neurofibroma Plexiform

Interventions

• DRUG

No Results Yet

NCT04589650 | ACTIVE_NOT_RECRUITING | PHASE2

206 participants

Study Assessing the Efficacy, Safety and PK of Alpelisib (BYL719) in Pediatric and Adult Patients With PIK3CA-related Overgrowth Spectrum

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2021-04-19

Completion:

2024-03-20

Conditions

• PIK3CA-related Overgrowth Spectrum (PROS)

Interventions

• DRUG

Results Available

NCT04582916 | RECRUITING | PHASE1

64 participants

PET Imaging of Cyclooxygenase in Participants With Major Depressive Disorder (MDD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2021-07-20

Completion:

2029-10-03

Conditions

• Depression

Interventions

• DRUG

No Results Yet

NCT04551560 | COMPLETED | NA

108 participants

Stress and Congestive Heart Failure

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2020-12-02

Completion:

2026-04-30

Conditions

• Congestive Heart Failure

Interventions

• OTHER

No Results Yet

NCT04547686 | COMPLETED | NA

916 participants

Efficacy of a Smoke-Free Homes Intervention

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2020-11-11

Completion:

2025-07-27

Conditions

• Cessation, Smoking

Interventions

• BEHAVIORAL

Results Available

NCT04485559 | RECRUITING | PHASE1

50 participants

Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2020-12-09

Completion:

2027-12-31

Conditions

• Recurrent World Health Organization (WHO) Grade II Glioma
• Low-grade Glioma
• High-Grade Glioma (HGG)

Interventions

• DRUG

No Results Yet

NCT04434092 | ACTIVE_NOT_RECRUITING | PHASE3

210 participants

A Study Evaluating the Efficacy and Safety of Crovalimab Versus Eculizumab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Not Previously Treated With Complement Inhibitors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2020-10-08

Completion:

2022-11-16

Conditions

• Paroxysmal Nocturnal Hemoglobinuria

Interventions

• DRUG

Results Available

NCT04432597 | COMPLETED | PHASE1/PHASE2

39 participants

HPV Vaccine PRGN-2009 Alone or in Combination With Anti-PDL1/TGF-Beta Trap (M7824) in Subjects With HPV Associated Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2020-08-11

Completion:

2022-11-22

Conditions

• HPV Positive Cancer
• Vulvar, Vaginal, Penile, Rectal Cancer
• Anal Cancer
• Oropharyngeal Cancer
• Cervical Cancer

Interventions

• BIOLOGICAL
• DIAGNOSTIC_TEST
• PROCEDURE

Results Available

NCT04353778 | COMPLETED | PHASE1/PHASE2

215 participants

Effects of Vagal Dysfunction on Gastrointestinal and Inflammatory Pathways in HIV

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2020-08-03

Completion:

2026-03-27

Conditions

• HIV
• Non-HIV
• Vagus Nerve Dysfunction

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT04312126 | RECRUITING

199 participants

The Beneficial Effects of Naps on Motor Learning

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2021-03-04

Completion:

2027-08-01

Conditions

• Stroke

Interventions

• DEVICE

No Results Yet

NCT04307108 | COMPLETED | NA

111 participants

Magic Glass Evaluation in People With Stroke

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2018-11-11

Completion:

2020-03-30

Conditions

• Stroke

Interventions

• DEVICE

No Results Yet

NCT04206215 | RECRUITING | NA

95 participants

Noninvasive Brain Stimulation for Treating Carpal Tunnel Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2021-04-16

Completion:

2027-07-02

Conditions

• Chronic Pain
• Carpal Tunnel Syndrome

Interventions

• DEVICE

No Results Yet

NCT04108455 | COMPLETED

47 participants

Biomarkers During Pregnancy

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2019-03-15

Completion:

2021-11-01

Conditions

• Diabetes Mellitus in Pregnancy
• Gestational Diabetes

Interventions

• OTHER

No Results Yet

NCT04050072 | ACTIVE_NOT_RECRUITING

837 participants

Patient-Reported Outcome Version of the Common Criteria for Adverse Events

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2019-12-16

Completion:

2026-12-31

Conditions

• Survivorship
• Cancer

Interventions

• OTHER

No Results Yet