Clinical Trials

NCT04582916 | RECRUITING | PHASE1

64 participants

PET Imaging of Cyclooxygenase in Participants With Major Depressive Disorder (MDD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2021-07-20

Completion:

2029-10-03

Conditions

• Depression

Interventions

• DRUG

No Results Yet

NCT04551560 | COMPLETED | NA

108 participants

Stress and Congestive Heart Failure

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2020-12-02

Completion:

2026-04-30

Conditions

• Congestive Heart Failure

Interventions

• OTHER

No Results Yet

NCT04547686 | COMPLETED | NA

916 participants

Efficacy of a Smoke-Free Homes Intervention

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2020-11-11

Completion:

2025-07-27

Conditions

• Cessation, Smoking

Interventions

• BEHAVIORAL

Results Available

NCT04485559 | RECRUITING | PHASE1

50 participants

Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2020-12-09

Completion:

2027-12-31

Conditions

• Recurrent World Health Organization (WHO) Grade II Glioma
• Low-grade Glioma
• High-Grade Glioma (HGG)

Interventions

• DRUG

No Results Yet

NCT04434092 | ACTIVE_NOT_RECRUITING | PHASE3

210 participants

A Study Evaluating the Efficacy and Safety of Crovalimab Versus Eculizumab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Not Previously Treated With Complement Inhibitors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2020-10-08

Completion:

2022-11-16

Conditions

• Paroxysmal Nocturnal Hemoglobinuria

Interventions

• DRUG

Results Available

NCT04432597 | COMPLETED | PHASE1/PHASE2

39 participants

HPV Vaccine PRGN-2009 Alone or in Combination With Anti-PDL1/TGF-Beta Trap (M7824) in Subjects With HPV Associated Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2020-08-11

Completion:

2022-11-22

Conditions

• HPV Positive Cancer
• Vulvar, Vaginal, Penile, Rectal Cancer
• Anal Cancer
• Oropharyngeal Cancer
• Cervical Cancer

Interventions

• BIOLOGICAL
• DIAGNOSTIC_TEST
• PROCEDURE

Results Available

NCT04353778 | COMPLETED | PHASE1/PHASE2

215 participants

Effects of Vagal Dysfunction on Gastrointestinal and Inflammatory Pathways in HIV

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2020-08-03

Completion:

2026-03-27

Conditions

• HIV
• Non-HIV
• Vagus Nerve Dysfunction

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT04312126 | RECRUITING

199 participants

The Beneficial Effects of Naps on Motor Learning

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2021-03-04

Completion:

2027-08-01

Conditions

• Stroke

Interventions

• DEVICE

No Results Yet

NCT04307108 | COMPLETED | NA

111 participants

Magic Glass Evaluation in People With Stroke

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2018-11-11

Completion:

2020-03-30

Conditions

• Stroke

Interventions

• DEVICE

No Results Yet

NCT04206215 | RECRUITING | NA

95 participants

Noninvasive Brain Stimulation for Treating Carpal Tunnel Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2021-04-16

Completion:

2027-07-02

Conditions

• Chronic Pain
• Carpal Tunnel Syndrome

Interventions

• DEVICE

No Results Yet

NCT04108455 | COMPLETED

47 participants

Biomarkers During Pregnancy

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2019-03-15

Completion:

2021-11-01

Conditions

• Diabetes Mellitus in Pregnancy
• Gestational Diabetes

Interventions

• OTHER

No Results Yet

NCT04050072 | ACTIVE_NOT_RECRUITING

837 participants

Patient-Reported Outcome Version of the Common Criteria for Adverse Events

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2019-12-16

Completion:

2026-12-31

Conditions

• Survivorship
• Cancer

Interventions

• OTHER

No Results Yet

NCT04047264 | RECRUITING | NA

100 participants

Feasibility of Intra- and Post-operative Microdialysis During Neurosurgery for Central Nervous System Lesions

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2020-01-01

Completion:

2027-09-01

Conditions

• Glioma
• Glioblastoma
• Metastatic Malignant Neoplasm in the Brain

Interventions

• PROCEDURE

No Results Yet

NCT03906292 | ACTIVE_NOT_RECRUITING | PHASE2

125 participants

Frontline Asciminib Combination in Chronic Phase CML

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2019-08-19

Completion:

2027-03-31

Conditions

• Chronic Myeloid Leukemia

Interventions

• DRUG

No Results Yet

NCT03812913 | COMPLETED

70 participants

Neuropsychological Assessment of Children and Adolescents With Turner Syndrome

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2019-09-05

Completion:

2025-05-13

Conditions

• Turner Syndrome
• Isolated Growth Hormone Deficiency
• Cognitive Functions
• Social Cognition
• Pediatrics

Interventions

• BEHAVIORAL

No Results Yet

NCT03789604 | COMPLETED | PHASE3

479 participants

A Study of CS1001 in Subjects With Stage IV Non-Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2018-12-13

Completion:

2023-05-15

Conditions

• Non Small Cell Lung Cancer

Interventions

• BIOLOGICAL

No Results Yet

NCT03732820 | ACTIVE_NOT_RECRUITING | PHASE3

895 participants

Study on Olaparib Plus Abiraterone as First-line Therapy in Men With Metastatic Castration-resistant Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2018-10-31

Completion:

2021-07-30

Conditions

• Metastatic Castration-resistant Prostate Cancer

Interventions

• DRUG

Results Available

NCT03728361 | COMPLETED | PHASE2

55 participants

Nivolumab and Temozolomide in Treating Patients With Recurrent or Refractory Small-Cell Lung Cancer or Advanced Neuroendocrine Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2018-12-31

Completion:

2025-12-02

Conditions

• Grade I Neuroendocrine Carcinoma
• Grade II Neuroendocrine Carcinoma
• Grade III Neuroendocrine Carcinoma
• Metastatic Neuroendocrine Carcinoma
• Neuroendocrine Carcinoma
• Recurrent Small Cell Lung Carcinoma
• Refractory Small Cell Lung Carcinoma
• Lung Cancer Stage IV
• Large Cell Neuroendocrine Carcinoma
• Neuroendocrine Tumors
• Small Cell Lung Cancer Metastatic
• Small-cell Lung Cancer

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT03719105 | RECRUITING | EARLY_PHASE1

40 participants

Chemoimmunotherapy and Allogeneic Stem Cell Transplant for NK T-cell Leukemia/Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2019-03-01

Completion:

2027-12-31

Conditions

• NK-Cell Lymphoma
• NK-Cell Leukemia
• Peripheral T Cell Lymphoma

Interventions

• DRUG

No Results Yet

NCT03701334 | ACTIVE_NOT_RECRUITING | PHASE3

5101 participants

A Trial to Evaluate Efficacy and Safety of Ribociclib With Endocrine Therapy as Adjuvant Treatment in Patients With HR+/HER2- Early Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2018-12-07

Completion:

2030-05-29

Conditions

• Early Breast Cancer

Interventions

• DRUG
• OTHER

No Results Yet

NCT03673748 | RECRUITING | PHASE2

20 participants

Treatment of Lupus Nephritis With Allogeneic Mesenchymal Stem Cells

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2022-12-27

Completion:

2027-12-31

Conditions

• Lupus Nephritis
• Lupus Erythematosus

Interventions

• DRUG

No Results Yet

NCT03616587 | ACTIVE_NOT_RECRUITING | PHASE1

396 participants

Study of AZD9833 Alone or in Combination in Women With Advanced Breast Cancer.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2018-10-11

Completion:

2024-09-16

Conditions

• ER+ HER2- Advanced Breast Cancer

Interventions

• DRUG

No Results Yet

NCT03573791 | RECRUITING

152 participants

Biomarkers for Predicting Neoadjuvant Chemoradio-resistance for Middle-low Advanced Rectal Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2018-05-21

Completion:

2027-05-21

Conditions

• Rectal Cancer
• Cancer of Rectum
• Cancer of the Rectum
• Neoplasms, Rectal
• Rectal Tumors
• Rectum Cancer
• Rectum Neoplasms

No Results Yet

NCT03541889 | RECRUITING | PHASE1

50 participants

REVEAL Biomarkers of Engraftment After Alternative Donor HSCT

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2020-10-21

Completion:

2026-12-14

Conditions

• Primary Graft Failure

Interventions

• DRUG

No Results Yet

NCT03537742 | COMPLETED | PHASE2

114 participants

Cardiac Allograft Vasculopathy Inhibition With Alirocumab

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2019-05-13

Completion:

2025-07-11

Conditions

• Vasculopathy

Interventions

• BIOLOGICAL

Results Available

NCT03491592 | COMPLETED | NA

210 participants

Web-based Physical Activity Intervention for Latinas

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2018-06-01

Completion:

2022-04-01

Conditions

• Inactivity

Interventions

• BEHAVIORAL

Results Available

NCT03473795 | ACTIVE_NOT_RECRUITING

6990 participants

Developing Non-Communicable Disease Registries in Africa : A Step Towards Providing Quality Data for Improving Patient Outcomes

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2018-03-16

Completion:

2027-03-31

Conditions

• Non-Communicable Disease

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT03367741 | ACTIVE_NOT_RECRUITING | PHASE2

82 participants

Cabozantinib S-malate and Nivolumab in Treating Patients With Advanced, Recurrent, or Metastatic Endometrial Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2018-04-16

Completion:

2025-05-09

Conditions

• Advanced Endometrial Carcinoma
• Metastatic Endometrial Carcinoma
• Recurrent Endometrial Carcinoma
• Stage III Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8
• Stage IV Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL

Results Available

NCT03365908 | ENROLLING_BY_INVITATION | NA

60 participants

Pain Management of ACL Reconstruction

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2017-10-09

Completion:

2027-07-01

Conditions

• Anterior Cruciate Ligament Rupture

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT03260400 | RECRUITING | NA

10 participants

Short-term Implanted Electrodes Following Regenerative Peripheral Nerve Surgery for Improving Prosthetic Limb Control Signals

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2017-12-11

Completion:

2029-05-05

Conditions

• Amputation Neuroma
• Amputation

Interventions

• DEVICE

No Results Yet

NCT03235531 | TERMINATED | PHASE4

3 participants

Assessment of Valproate on Ethanol Withdrawal

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2017-07-11

Completion:

2019-06-25

Conditions

• Alcohol Dependence
• Alcohol Withdrawal Syndrome
• Trauma
• Heavy Drinking
• Alcohol Use Disorder

Interventions

• DRUG

No Results Yet

NCT03212274 | ACTIVE_NOT_RECRUITING | PHASE2

89 participants

Olaparib in Treating Patients With Advanced Glioma, Cholangiocarcinoma, or Solid Tumors With IDH1 or IDH2 Mutations

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2019-01-30

Completion:

2025-04-02

Conditions

• Advanced Malignant Solid Neoplasm
• Glioblastoma
• Recurrent Cholangiocarcinoma
• Recurrent Glioma
• Recurrent Malignant Solid Neoplasm
• WHO Grade 2 Glioma
• WHO Grade 3 Glioma

Interventions

• PROCEDURE
• DRUG

Results Available

NCT03198026 | ACTIVE_NOT_RECRUITING | PHASE2

29 participants

Obinutuzumab and Ibrutinib as Front Line Therapy in Treating Patients With Indolent Non-Hodgkin's Lymphomas

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2018-02-20

Completion:

2023-10-24

Conditions

• Non-Hodgkin's Lymphoma
• Ann Arbor Stage II Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue
• Ann Arbor Stage II Follicular Lymphoma
• Ann Arbor Stage II Nodal Marginal Zone Lymphoma
• Ann Abor Stage III B-Cell Non-Hodgkin Lymphoma
• Ann Arbor Stage III Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue
• Ann Arbor Stage III Follicular Lymphoma
• Ann Arbor Stage III Nodal Marginal Zone Lymphoma
• Ann Arbor Stage IV B-Cell Non-Hodgkin Lymphoma
• Ann Arbor Stage IV Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue
• Ann Arbor Stage IV Follicular Lymphoma
• Ann Arbor Stage IV Nodal Marginal Zone Lymphoma
• Grade 1 Follicular Lymphoma
• Grade 2 Follicular Lymphoma
• Grade 3a Follicular Lymphoma
• Indolent Non-hodgkin Lymphoma
• Stage II Splenic Marginal Zone Lymphoma
• Stage III Splenic Marginal Zone Lymphoma
• Stage IV Splenic Marginal Zone Lymphoma

Interventions

• DRUG
• BIOLOGICAL
• OTHER

Results Available

NCT03195777 | COMPLETED | NA

50 participants

Novel PET/CT and Treatment Strategies to Reduce PTS Following DVT

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2017-12-20

Completion:

2025-06-27

Conditions

• Deep Venous Thrombosis
• Post-thrombotic Syndrome

Interventions

• DEVICE

Results Available

NCT03192046 | COMPLETED | NA

10 participants

Bracing for Walking in Parkinson's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2016-09-30

Completion:

2020-12-31

Conditions

• Gait Disorders, Neurologic
• Parkinson Disease

Interventions

• DEVICE
• OTHER

Results Available

NCT03173950 | TERMINATED | PHASE2

136 participants

Immune Checkpoint Inhibitor Nivolumab in People With Recurrent Select Rare CNS Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2017-07-13

Completion:

2025-06-23

Conditions

• Medulloblastoma
• Ependymoma
• Pineal Region Tumors
• Choroid Plexus Tumors
• Atypical/Malignant Meningioma

Interventions

• DRUG
• DIAGNOSTIC_TEST
• OTHER

Results Available

NCT03122197 | RECRUITING | EARLY_PHASE1

39 participants

Study of Letrozole in Recurrent Gliomas

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2017-05-16

Completion:

2027-09-01

Conditions

• Brain Tumor

Interventions

• DRUG

No Results Yet

NCT03121209 | COMPLETED | PHASE3

392 participants

Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial - Hemodynamics (CREST-H)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2018-01-18

Completion:

2025-09-12

Conditions

• Internal Carotid Artery Stenosis
• Cognitive Impairment

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT03111745 | COMPLETED

730 participants

Retrospective Study of Viral Reactivation Across All Bone Marrow Transplant Protocols Since 2010

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2017-04-13

Completion:

2018-12-29

Conditions

• Viral Infections

No Results Yet

NCT03106779 | COMPLETED | PHASE3

233 participants

Study of Efficacy of CML-CP Patients Treated With ABL001 Versus Bosutinib, Previously Treated With 2 or More TKIs

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2017-10-26

Completion:

2020-05-25

Conditions

• Chronic Myelogenous Leukemia

Interventions

• DRUG

Results Available