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Clinical Trials

Showing trials with last updates posted in 2026.

NCT07516444 | RECRUITING | NA
730 participants

VDyne Transcatheter Tricuspid Valve Replacement Study to Evaluate Safety and Clinical Efficacy in Patients With Symptomatic Severe Tricuspid Valve Regurgitation (TRIVITA Pivotal Trial)

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-17
Start Date:
2026-07-28
Completion:
2029-06-30
Conditions
  • Tricuspid Valve Regurgitation
  • Tricuspid Valve Disease
  • Cardiovascular Diseases (CVD)
  • Heart Valve Diseases
  • Tricuspid Valve Insufficiency
  • Severe Heart Valve Disease
  • Randomized Controlled Trial (RCT)
  • Symptomatic Tricuspid Regurgitation
Interventions
  • DEVICE
No Results Yet
NCT07489066 | RECRUITING | PHASE2
120 participants

Symbiotic-Lung-10: A Study to Learn About PF-08634404 Alone or in Combination in Early-stage or Locally Advanced NSCLC

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-17
Start Date:
2026-06-30
Completion:
2028-07-29
Conditions
  • Carcinoma
  • Non-Small-Cell Lung
  • Lung Cancer (NSCLC)
  • Lung Neoplasms
  • Carcinoma, Non-Small-Cell Lung (NSCLC)
  • Lung Disease
  • Non-Small Cell Lung Cancer
  • Non-small Cell Lung Cancer, Non-squamous
  • Non-small Cell Lung Cancer, Squamous
Interventions
  • BIOLOGICAL
  • DRUG
No Results Yet
NCT07488559 | RECRUITING | NA
120 participants

Engage Coaching (R33 Phase)

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-17
Start Date:
2026-06-30
Completion:
2028-12-31
Conditions
  • Social Connection
  • Loneliness
  • Suicide Ideation
  • Social-emotional Quality of Life
Interventions
  • BEHAVIORAL
No Results Yet
NCT07476287 | RECRUITING | PHASE2
40 participants

Symbiotic-Lung-14: A Study to Learn About the Study Medicine Called PF08634404 in Combination With Chemotherapy in Adult Participants With Transformed Small Cell Lung Cancer

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-17
Start Date:
2026-07-02
Completion:
2028-03-19
Conditions
  • Small Cell Lung Cancer
  • Small Cell Lung Cancer ( SCLC )
  • Transformed Small Cell Lung Cancer
  • Lung Neoplasms
  • Carcinoma, Small Cell Lung
  • Small Cell Cancer Of The Lung
Interventions
  • DRUG
No Results Yet
NCT07448597 | RECRUITING | PHASE4
642 participants

Progesterone Preeclampsia

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-17
Start Date:
2026-08-13
Completion:
2028-08-01
Conditions
  • Preeclampsia
  • Hypertensive Disorder of Pregnancy
Interventions
  • DRUG
No Results Yet
NCT07441681 | RECRUITING | PHASE3
454 participants

Comparing Radiation Plus Cetuximab to Radiation Plus Chemotherapy in People With Head and Neck Cancer Who Cannot Receive Cisplatin

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-17
Start Date:
2026-07-31
Completion:
2035-11-30
Conditions
  • Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
  • Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
  • Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
  • Head and Neck Squamous Cell Carcinoma
  • Stage III Hypopharyngeal Carcinoma AJCC v8
  • Stage III Laryngeal Cancer AJCC v8
  • Stage III Lip and Oral Cavity Cancer AJCC v8
  • Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8
  • Stage IVA Hypopharyngeal Carcinoma AJCC v8
  • Stage IVA Laryngeal Cancer AJCC v8
  • Stage IVA Lip and Oral Cavity Cancer AJCC v8
  • Stage IVA Oropharyngeal (p16-Negative) Carcinoma AJCC v8
  • Stage IVB Hypopharyngeal Carcinoma AJCC v8
  • Stage IVB Laryngeal Cancer AJCC v8
  • Stage IVB Lip and Oral Cavity Cancer AJCC v8
  • Stage IVB Oropharyngeal (p16-Negative) Carcinoma AJCC v8
Interventions
  • PROCEDURE
  • DRUG
  • BIOLOGICAL
  • RADIATION
  • OTHER
No Results Yet
NCT07440290 | RECRUITING | PHASE2/PHASE3
30 participants

DETERMINE Trial Treatment Arm 07: Dabrafenib in Combination With Trametinib in Adult, Paediatric and Teenage/Young Adult Patients With BRAF V600 Mutation-Positive Cancers.

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-17
Start Date:
2026-04-01
Completion:
2029-10-31
Conditions
  • Haematological Malignancy
  • Malignant Neoplasm
  • Lymphoproliferative Disorders
  • Neoplasms by Histologic Type
  • Neoplasms by Site
  • Gastrointestinal Cancer
  • Non-Melanoma Skin Cancer (NMSC)
  • Langerhans Cell Histiocytosis (LCH)
  • Cancer
  • Erdheim-Chester Disease
  • Thyroid Carcinoma, Papillary
  • Ovarian Neoplasms
  • Colorectal Neoplasms
  • Laryngeal Neoplasms
  • Carcinoma, Non-Small Cell-Lung
  • Glioma
  • Multiple Myeloma
  • Thyroid Carcinoma, Anaplastic
  • Solid Tumour
  • Pancreatic Diseases
Interventions
  • DRUG
No Results Yet
NCT07392892 | RECRUITING | PHASE2/PHASE3
840 participants

Symbiotic-GI-16: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Gastroesophageal Cancer

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-17
Start Date:
2026-05-14
Completion:
2031-07-22
Conditions
  • Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction , or Esophageal Adenocarcinoma
  • Metastatic Gastric Cancer
  • Gastroesophageal Junction Cancer
  • Esophageal Adenocarcinoma
Interventions
  • BIOLOGICAL
  • DRUG
No Results Yet
NCT07391605 | RECRUITING | PHASE2
60 participants

Descartes-08 in Autoantibody Myositis

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-17
Start Date:
2026-04-28
Completion:
2027-11-30
Conditions
  • Antisynthetase Syndrome
Interventions
  • DRUG
  • OTHER
No Results Yet
NCT07387354 | WITHDRAWN | PHASE1/PHASE2
0 participants

Pacritinib With Aza for Upfront Myelodysplastic Syndrome

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-17
Start Date:
2026-09-30
Completion:
2027-01-31
Conditions
  • Myelodysplastic Syndromes
  • MDS
  • Myelodysplastic Syndrome, Unclassifiable
  • Hematologic Diseases
  • Bone Marrow Disease
  • Myeloproliferative Neoplasm
Interventions
  • DRUG
  • PROCEDURE
  • DIAGNOSTIC_TEST
  • OTHER
No Results Yet
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