Clinical Trials Updated in 2026

NCT06574152 | RECRUITING | NA

90 participants

Effect of Photobiomodulation on Pain and Healing of the Vertical Releasing Incision After Endodontic Microsurgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2024-08-20
Completion:: 2028-05-04

Conditions

Apical Periodontitis
Endodontically Treated Teeth
Endodontic Disease
Apical Cyst
Apical Granuloma
Periradicular Disease
Previous Endodontic Treatment

Interventions

DEVICE

No Results Yet

NCT06570655 | COMPLETED | PHASE1

12 participants

The Study of Pharmacokinetics and Pharmacodynamics of Huperzine A Injection in Healthy Chinese Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2024-05-16
Completion:: 2024-06-20

Conditions

Healthy Subjects

Interventions

DRUG

No Results Yet

NCT06569082 | RECRUITING | NA

21 participants

CD34+ Selected Stem Cell for Poor Graft Function or Graft Failure

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2024-10-31
Completion:: 2034-08-31

Conditions

Graft Failure
Poor Graft Function

Interventions

DEVICE
PROCEDURE

No Results Yet

NCT06562270 | RECRUITING

1500 participants

CorEvitas International Adolescent Alopecia Areata (AA) Drug Safety and Effectiveness Registry

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-17
Start Date:: 2024-03-07
Completion:: 2099-12-31

Conditions

Alopecia Areata

No Results Yet

NCT06561386 | RECRUITING | PHASE3

1000 participants

A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2024-10-07
Completion:: 2030-07-30

Conditions

Non-small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT06560021 | ENROLLING_BY_INVITATION | NA

1642 participants

Utility of Random Biopsies in Patients With Inflammatory Bowel Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-01-03
Completion:: 2028-12-31

Conditions

Inflammatory Bowel Diseases
Crohn Disease
Ulcerative Colitis

Interventions

OTHER

No Results Yet

NCT06558201 | ENROLLING_BY_INVITATION | NA

50 participants

Open Label Extension Study of NCT06221852

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2024-08-28
Completion:: 2027-09-30

Conditions

Bipolar I Disorder
Schizoaffective Disorder
Psychosis

Interventions

OTHER

No Results Yet

NCT06550804 | ACTIVE_NOT_RECRUITING | PHASE3

126 participants

Testing a Real-time Electronic Antiretroviral Adherence Monitoring Intervention

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2024-10-01
Completion:: 2027-03-31

Conditions

HIV Infections
Adherence, Medication

Interventions

BEHAVIORAL

No Results Yet

NCT06542497 | COMPLETED | PHASE3

569 participants

Evaluate Efficacy and Safety of POS to Improve Distance-corrected Near Visual in Participants With Presbyopia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2024-08-15
Completion:: 2025-04-03

Conditions

Presbyopia

Interventions

DRUG

Results Available

NCT06535802 | COMPLETED

38 participants

iCCaRE Consortium Pilot Project 1: Feasibility of a Point of Prostate Cancer Diagnosis Intervention for Newly Diagnosed Black Men

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-17
Start Date:: 2023-11-20
Completion:: 2026-06-23

Conditions

Prostate Carcinoma

Interventions

OTHER

No Results Yet

NCT06532279 | RECRUITING | PHASE2

98 participants

Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-06-23
Completion:: 2027-01-01

Conditions

Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Head and Neck Squamous Cell Carcinoma
Hypopharyngeal Squamous Cell Carcinoma
Laryngeal Squamous Cell Carcinoma
Nasopharyngeal Squamous Cell Carcinoma
Oral Cavity Squamous Cell Carcinoma
Oropharyngeal Squamous Cell Carcinoma
Stage 0 Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8
Stage 0 Hypopharyngeal Carcinoma AJCC v8
Stage 0 Nasopharyngeal Carcinoma AJCC v8
Stage 0 Oropharyngeal (p16-Negative) Carcinoma AJCC v8
Stage I Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8
Stage I Hypopharyngeal Carcinoma AJCC v8
Stage I Laryngeal Cancer AJCC v8
Stage I Lip and Oral Cavity Cancer AJCC v8
Stage I Nasopharyngeal Carcinoma AJCC v8
Stage I Oropharyngeal (p16-Negative) Carcinoma AJCC v8
Stage II Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8
Stage II Hypopharyngeal Carcinoma AJCC v8
Stage II Laryngeal Cancer AJCC v8
Stage II Lip and Oral Cavity Cancer AJCC v8
Stage II Nasopharyngeal Carcinoma AJCC v8
Stage II Oropharyngeal (p16-Negative) Carcinoma AJCC v8
Stage III Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8
Stage III Hypopharyngeal Carcinoma AJCC v8
Stage III Laryngeal Cancer AJCC v8
Stage III Lip and Oral Cavity Cancer AJCC v8
Stage III Nasopharyngeal Carcinoma AJCC v8
Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8
Stage IVA Hypopharyngeal Carcinoma AJCC v8
Stage IVA Laryngeal Cancer AJCC v8
Stage IVA Lip and Oral Cavity Cancer AJCC v8
Stage IVA Nasopharyngeal Carcinoma AJCC v8
Stage IVA Oropharyngeal (p16-Negative) Carcinoma AJCC v8
Stage IVB Hypopharyngeal Carcinoma AJCC v8
Stage IVB Laryngeal Cancer AJCC v8
Stage IVB Lip and Oral Cavity Cancer AJCC v8
Stage IVB Oropharyngeal (p16-Negative) Carcinoma AJCC v8
Stomatitis

Interventions

OTHER
PROCEDURE
DRUG
RADIATION

No Results Yet

NCT06528301 | RECRUITING | PHASE1

106 participants

A Phase 1 Study of UB-VV111 With and Without Rapamycin in Relapsed/Refractory CD19+ B-cell Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-03-10
Completion:: 2029-03-31

Conditions

Lymphoma, B-Cell
Lymphoma, Non-Hodgkin (NHL)
Lymphoma, Large B-Cell, Diffuse (DLBCL)
Chronic Lymphocytic Leukemia (CLL)

Interventions

GENETIC
DRUG

No Results Yet

NCT06527157 | RECRUITING

4500 participants

Investigations of Reproductive Cancers in Women

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-17
Start Date:: 2024-07-30
Completion:: 2026-10-30

Conditions

Uterine Cancer

No Results Yet

NCT06525584 | RECRUITING | NA

196 participants

Ketamine Infusion as a Method of Cerebral Protection in Children

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2023-11-05
Completion:: 2028-12-30

Conditions

Brain Injuries

Interventions

DRUG
OTHER

No Results Yet

NCT06519422 | RECRUITING | PHASE3

4000 participants

Tranexamic Acid for Anaemia Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-08-10
Completion:: 2028-08-31

Conditions

Anaemia

Interventions

DRUG

No Results Yet

NCT06500481 | RECRUITING | PHASE3

115 participants

Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-03-04
Completion:: 2028-07-31

Conditions

Anatomic Stage IV Breast Cancer AJCC v8
Metastatic Breast Carcinoma
Metastatic Lung Non-Small Cell Carcinoma
Metastatic Malignant Neoplasm in the Leptomeninges
Stage IV Lung Cancer AJCC v8

Interventions

PROCEDURE
RADIATION
OTHER

No Results Yet

NCT06500455 | RECRUITING | PHASE3

269 participants

Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2024-12-12
Completion:: 2028-06-30

Conditions

Anatomic Stage IV Breast Cancer AJCC v8
Metastatic Breast Carcinoma
Metastatic Digestive System Carcinoma
Metastatic Lung Non-Small Cell Carcinoma
Metastatic Malignant Neoplasm in the Brain
Metastatic Malignant Solid Neoplasm
Metastatic Melanoma
Metastatic Renal Cell Carcinoma
Stage IV Lung Cancer AJCC v8
Stage IV Renal Cell Cancer AJCC v8

Interventions

PROCEDURE
RADIATION

No Results Yet

NCT06493006 | COMPLETED

367 participants

Promoting Sustainable and Active Mobility Among Employees and Students

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-17
Start Date:: 2024-08-01
Completion:: 2026-03-30

Conditions

Mobility on the Way to Work and Health-related Outcomes

No Results Yet

NCT06492616 | RECRUITING | PHASE3

4220 participants

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2024-09-27
Completion:: 2029-08-31

Conditions

Breast Cancer

Interventions

DRUG

No Results Yet

NCT06492486 | RECRUITING | PHASE2

60 participants

Glioma Adaptive Radiotherapy With Development of an Artificial Intelligence Workflow

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-07-27
Completion:: 2028-07-30

Conditions

Diffuse Glioma
Glioblastoma
Adaptive Radiotherapy
Artificial Intelligence

Interventions

RADIATION

No Results Yet

NCT06491446 | COMPLETED | PHASE1/PHASE2

141 participants

Evaluating Clearance of High-Risk HPV and Safety After Administration of ABI-2280 Vaginal Inserts

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2024-03-27
Completion:: 2025-10-17

Conditions

Human Papillomavirus Infection

Interventions

DRUG

No Results Yet

NCT06487559 | ACTIVE_NOT_RECRUITING | PHASE1

3 participants

A Study to Assess the Adverse Events and How Intravenously Infused Livmoniplimab in Combination With Budigalimab Moves Through the Bodies of Adult Chinese Participants With Locally Advanced or Metastatic Hepatocellular Carcinoma (HCC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2024-09-11
Completion:: 2027-02-28

Conditions

Hepatocellular Carcinoma (HCC)

Interventions

DRUG

No Results Yet

NCT06482268 | RECRUITING | PHASE1

7 participants

Transplantation of Human iPS Cell-derived Dopaminergic Progenitors (CT1-DAP001) for Parkinson's Disease (Phase I/II)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2024-06-01
Completion:: 2027-12-28

Conditions

PD - Parkinson's Disease

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT06477068 | COMPLETED | NA

361 participants

Effect of a Medication Reminder Mobile Application

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2024-06-01
Completion:: 2026-03-09

Conditions

Infertility

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT06458075 | RECRUITING | NA

480 participants

Intervention to Improve Communication and Medication Adherence in Lupus

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2024-07-01
Completion:: 2027-10-31

Conditions

Systemic Lupus Erythematosus

Interventions

BEHAVIORAL

No Results Yet

NCT06457152 | COMPLETED | NA

1136 participants

Multi-Center Project: Building Electronic Tools To Enhance and Reinforce CArdiovascular REcommendations - Heart Failure

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-04-04
Completion:: 2025-12-04

Conditions

Heart Failure

Interventions

OTHER

No Results Yet

NCT06454903 | RECRUITING | NA

75 participants

Developing a Smartphone Application to Support Veteran Opioid Use Disorder Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-04-02
Completion:: 2029-10-31

Conditions

Opioid-Related Disorders
Psychosocial Functioning
Quality of Life

Interventions

BEHAVIORAL

No Results Yet

NCT06439485 | RECRUITING | PHASE1/PHASE2

25 participants

Phase I/II Trial of Pemigatinib in Combination With Atezolizumab and Bevacizumab for Treatment of Advanced Cholangiocarcinoma With FGFR2 Fusion

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2024-11-19
Completion:: 2028-02-22

Conditions

Advanced Cholangiocarcinoma
FGFR2 Fusion

Interventions

DRUG

No Results Yet

NCT06420297 | TERMINATED | PHASE3

168 participants

OLE Study of Carbetocin Nasal Spray for the Treatment of Hyperphagia in Prader-Willi Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2024-03-11
Completion:: 2025-12-19

Conditions

Hyperphagia in Prader-Willi Syndrome

Interventions

DRUG

No Results Yet

NCT06395792 | WITHDRAWN

0 participants

A Study on Dravet Syndrome (DS) and Lennox-Gastaut Syndrome (LGS) in Children, Teenagers and Adults in Portugal

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-17
Start Date:: 2024-12-01
Completion:: 2025-07-01

Conditions

Dravet Syndrome (DS)
Lennox-Gastaut Syndrome (LGS)

Interventions

OTHER

No Results Yet

NCT06372145 | ACTIVE_NOT_RECRUITING | PHASE3

2500 participants

A Study to Investigate Long-term Safety and Tolerability of Tolebrutinib in Participants With Multiple Sclerosis.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2024-04-16
Completion:: 2029-04-30

Conditions

Relapsing Multiple Sclerosis
Secondary Progressive Multiple Sclerosis
Progressive Relapsing Multiple Sclerosis

Interventions

DRUG

No Results Yet

NCT06358872 | RECRUITING | PHASE4

3300000 participants

Azithromycin for Child Survival in Niger II

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2024-04-29
Completion:: 2028-04-29

Conditions

Mortality
Antimicrobial Resistance

Interventions

DRUG

No Results Yet

NCT06358573 | RECRUITING | PHASE2

61 participants

Intratumoral INT230-6 Followed by Neoadjuvant Immuno-chemotherapy in Patients With Early TNBC. INVINCIBLE-4-SAKK

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2024-10-24
Completion:: 2028-10-31

Conditions

Triple-negative Breast Cancer
TNBC - Triple-Negative Breast Cancer

Interventions

DRUG
OTHER

No Results Yet

NCT06349070 | ENROLLING_BY_INVITATION | NA

1050 participants

RESTORE - Phase II

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2024-01-26
Completion:: 2027-01-30

Conditions

Maternal Health

Interventions

BEHAVIORAL

No Results Yet

NCT06338150 | COMPLETED

100 participants

Precision Medicine Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-17
Start Date:: 2024-07-17
Completion:: 2026-04-09

Conditions

Multiple Myeloma

No Results Yet

NCT06328777 | RECRUITING | PHASE2/PHASE3

37 participants

RESET-SSc: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201, a CD19-CAR T Cell Therapy, in Subjects With Systemic Sclerosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2024-07-02
Completion:: 2029-07-31

Conditions

Systemic Sclerosis
Scleroderma
Interstitial Lung Diseases

Interventions

BIOLOGICAL

No Results Yet

NCT06315881 | RECRUITING | PHASE2

160 participants

Informing Oral Nicotine Pouch Regulations to Promote Public Health

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-01-13
Completion:: 2028-01-31

Conditions

Tobacco-Related Carcinoma

Interventions

PROCEDURE
DRUG
OTHER

No Results Yet

NCT06312579 | ACTIVE_NOT_RECRUITING | NA

26 participants

At-Home Exercise Study for Veterans With Healed Diabetic Foot Ulcers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2024-10-01
Completion:: 2026-06-30

Conditions

Diabetic Foot Ulcer

Interventions

BEHAVIORAL

No Results Yet

NCT06310031 | RECRUITING | NA

780 participants

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2024-10-28
Completion:: 2028-02-29

Conditions

Cardiovascular Diseases
Heart Diseases
Heart Failure

Interventions

DEVICE

No Results Yet

NCT06306300 | RECRUITING | PHASE4

30000 participants

Safety and Efficacy of Decentralized HCV Treatment vs Standard-of-Care in Rio de Janeiro (Brazil)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2022-07-04
Completion:: 2026-12-31

Conditions

Hepatitis C

Interventions

DRUG
DIAGNOSTIC_TEST

No Results Yet