Evaluate Efficacy and Safety of POS to Improve Distance-corrected Near Visual in Participants With Presbyopia

NCT06542497 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 569

Last updated 2026-03-12

No results posted yet for this study

Summary

Safety and efficacy of POS in participants with presbyopia

Conditions

Interventions

DRUG

0.75% phentolamine ophthalmic solution

Once daily dosing

DRUG

Placebo

Once daily dosing

Sponsors & Collaborators

  • Ocuphire Pharma, Inc.

    lead INDUSTRY

Principal Investigators

  • Jay V Pepose, MD · Ocuphire Pharma

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
45 Years
Max Age
64 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-08-15
Primary Completion
2025-04-03
Completion
2026-01-22
FDA Drug
Yes

Countries

  • United States

Study Locations

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Entities

Drugs
Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06542497 on ClinicalTrials.gov