Clinical Trials Updated in 2026

NCT05878769 | ACTIVE_NOT_RECRUITING | PHASE3

2000 participants

A Study to Evaluate the Long-Term Safety of Astegolimab in Participants With Chronic Obstructive Pulmonary Disease (COPD)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-06-28
Completion:: 2027-06-30

Conditions

Chronic Obstructive Pulmonary Disease

Interventions

DRUG

No Results Yet

NCT05878483 | RECRUITING | NA

44658 participants

Autonomous Blood Drawing Optimization and Performance Testing

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-07-21
Completion:: 2029-12-31

Conditions

Venipuncture
Phlebotomy

Interventions

DEVICE

No Results Yet

NCT05869903 | ACTIVE_NOT_RECRUITING | PHASE3

3127 participants

A Study of Orforglipron (LY3502970) in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-06-05
Completion:: 2025-07-25

Conditions

Obesity
Overweight
Overweight or Obesity

Interventions

DRUG

Results Available

NCT05864534 | RECRUITING | PHASE2

25 participants

Phase 2a Immune Modulation With Ultrasound for Newly Diagnosed Glioblastoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2024-01-19
Completion:: 2031-07-31

Conditions

Newly Diagnosed Glioblastoma
Glioblastoma, Isocitric Dehydrogenase (IDH)-Wildtype
Gliosarcoma
Glioblastoma Multiforme

Interventions

DRUG
DEVICE

No Results Yet

NCT05853575 | ACTIVE_NOT_RECRUITING | PHASE2

200 participants

Trial of Two Adagrasib Dosing Regimens in NSCLC With KRAS G12C Mutation (KRYSTAL 21)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2024-02-01
Completion:: 2026-10-30

Conditions

Advanced Cancer
Metastatic Cancer
Malignant Neoplasm of Lung

Interventions

DRUG

No Results Yet

NCT05852860 | ENROLLING_BY_INVITATION | NA

500 participants

A Patient-Oriented Research Mentoring Program in Tobacco Dependence and Implementation Science Research

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-12-01
Completion:: 2027-02-01

Conditions

HIV
Smoking
Tobacco Use
Nicotine Dependence

Interventions

OTHER

No Results Yet

NCT05846516 | ACTIVE_NOT_RECRUITING | PHASE1

59 participants

A Study to Evaluate ATP150/ATP152/ATP162, VSV-GP154 and Ezabenlimab in Patients With Pancreatic Ductal Adenocarcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-05-11
Completion:: 2027-03-08

Conditions

Pancreatic Ductal Adenocarcinoma

Interventions

DRUG

No Results Yet

NCT05844865 | RECRUITING | NA

20 participants

Patient Derived Vascularized MicroTumor Model of Gastrointestinal Peritoneal Carcinomatosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-05-04
Completion:: 2026-12-31

Conditions

Peritoneal Carcinomatosis
Gastrointestinal Peritoneal Carcinomatosis

Interventions

OTHER

No Results Yet

NCT05842031 | SUSPENDED

20 participants

Assessment of Patient Experience and Needs for Patients Undergoing Invasive Inguinal Lymph Node Procedures for Penile Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-04-14
Completion:: 2026-12-31

Conditions

Penile Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT05840367 | COMPLETED

22 participants

Mothers' Experience of Category 1 Cesarean Section

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-06-01
Completion:: 2025-03-01

Conditions

Cesarean Section Complications

Interventions

BEHAVIORAL

No Results Yet

NCT05840003 | COMPLETED | NA

116 participants

Image Quality: Ultra-Low Dose Scanner Versus Standard Dose Conventional Scanner for Thoraco-abdominopelvic Scans

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-09-15
Completion:: 2024-07-15

Conditions

Imaging, Diagnostic
Lung Diseases
Abdomen Disease
Pelvis Disease
Bone Diseases

Interventions

RADIATION

No Results Yet

NCT05835310 | RECRUITING | PHASE3

100 participants

An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2024-03-14
Completion:: 2028-10-05

Conditions

Systemic Lupus Erythematosus

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT05814627 | COMPLETED | PHASE3

487 participants

Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib Compared to Subcutaneous Adalimumab in Adult Participants With Moderate to Severe Rheumatoid Arthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-06-15
Completion:: 2026-07-15

Conditions

Rheumatoid Arthritis

Interventions

DRUG

No Results Yet

NCT05797610 | ACTIVE_NOT_RECRUITING | PHASE3

459 participants

A Study to Evaluate the Efficacy and Safety of Sefaxersen (RO7434656) in Participants With Primary Immunoglobulin A (IgA) Nephropathy at High Risk of Progression

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-08-08
Completion:: 2026-08-31

Conditions

Primary IgA Nephropathy

Interventions

DRUG

No Results Yet

NCT05793320 | COMPLETED | NA

250 participants

Carpal Tunnel Release With Risk Factors for Amyloidosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-08-03
Completion:: 2025-12-03

Conditions

Amyloidosis

Interventions

PROCEDURE

No Results Yet

NCT05792189 | RECRUITING | NA

100 participants

Distal Femur Fx: ORIF(Open Reduction and Internal Fixation) vs DFR (Distal Femur Replacement Total Knee Arthroplasty)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-04-12
Completion:: 2029-04-01

Conditions

Distal Femur Fracture

Interventions

OTHER

No Results Yet

NCT05776953 | COMPLETED | PHASE4

86 participants

Evaluation of the Effects of Ketorolac Dose on Duration of Analgesia in Emergency Department (ED) Renal Colic Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-12-21
Completion:: 2026-08-12

Conditions

Renal Colic
Flank Pain
Emergencies
Analgesia

Interventions

DRUG

No Results Yet

NCT05763537 | RECRUITING | NA

75 participants

Understanding the Role of Doulas in Supporting People With PMADs

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2024-11-26
Completion:: 2026-12-31

Conditions

Maternal Health
Pregnancy
Delivery, Obstetric
Self Efficacy
Social Support
Mental Health
Substance-Related Disorders
Postpartum Depression
Depression
Mental Health Services

Interventions

BEHAVIORAL

No Results Yet

NCT05759481 | COMPLETED | PHASE2

65 participants

Prevention of Post-Operative Nausea and Vomiting With Propofol Infusion

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2024-02-01
Completion:: 2025-03-12

Conditions

Post-operative Nausea and Vomiting

Interventions

DRUG

Results Available

NCT05758116 | COMPLETED | PHASE2

5 participants

Tislelizumab Consolidation Therapy After Radiotherapy or Sequential Chemoradiation in Locally Advanced NSCLC Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2022-07-07
Completion:: 2026-06-30

Conditions

Non-small Cell Lung Cancer
Consolidation Immunotherapy
Radiotherapy or Sequential Chemoradiation

Interventions

DRUG

No Results Yet

NCT05753176 | COMPLETED | NA

412 participants

Online 1-Day CBT-Based Workshops for Preventing Postpartum Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2022-11-10
Completion:: 2025-12-12

Conditions

Postpartum Depression
Postpartum Anxiety

Interventions

BEHAVIORAL

No Results Yet

NCT05750953 | COMPLETED | NA

204 participants

Nurse-assisted Intervention "eHealth@ Hospital -2-home"

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-05-05
Completion:: 2025-12-15

Conditions

Non Communicable Diseases
Heart Failure
Colon Rectal Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT05748171 | RECRUITING | PHASE2

100 participants

A Study to Learn More About the Study Medicine Called Inotuzumab Ozogamicin (InO) in Children (1 to <18 Years) With First Relapse ALL

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-05-17
Completion:: 2033-05-21

Conditions

ACUTE LYMPHOBLASTIC LEUKEMIA

Interventions

DRUG

No Results Yet

NCT05732870 | RECRUITING

2000 participants

OSTEOMICS: Identifying Regulators of Bone Homeostasis

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-01-12
Completion:: 2027-12-31

Conditions

Osteoporosis
Osteoarthritis
Bone Diseases
Bone Fracture
Bone Marrow Disease

Interventions

PROCEDURE

No Results Yet

NCT05725655 | ACTIVE_NOT_RECRUITING | NA

30 participants

Hot Water Immersion After Myocardial Infarction

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-10-26
Completion:: 2027-07-30

Conditions

Cardiac Disease
Cardiac Rehabilitation

Interventions

OTHER

No Results Yet

NCT05722327 | ACTIVE_NOT_RECRUITING | PHASE1

24 participants

Phase I Trial of Adagrasib (MRTX849) in Combination With Cetuximab and Irinotecan in Patients With Colorectal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-12-06
Completion:: 2027-09-30

Conditions

Colon Cancer
Colorectal Cancer

Interventions

DRUG

No Results Yet

NCT05713279 | TERMINATED | NA

13 participants

Study of Flonoltinib Maleate Tablets in the Treatment of Severe Novel Coronavirus (COVID-19) Infection

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-05-23
Completion:: 2023-12-01

Conditions

COVID-19

Interventions

DRUG

No Results Yet

NCT05705193 | COMPLETED | NA

39 participants

Brain-Training Treatment for Long COVID in Older Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-04-07
Completion:: 2025-12-13

Conditions

Post-Acute COVID-19 Syndrome

Interventions

OTHER

No Results Yet

NCT05685303 | RECRUITING | NA

700 participants

Alleviant ALLAY-HF Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-01-10
Completion:: 2027-12-01

Conditions

Heart Failure

Interventions

DEVICE
OTHER

No Results Yet

NCT05664516 | RECRUITING | PHASE2

60 participants

A Study of the Effects of Oxytocin in Adults With Binge-eating Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-03-07
Completion:: 2026-12-31

Conditions

Binge-eating Disorder

Interventions

DRUG

No Results Yet

NCT05650749 | ENROLLING_BY_INVITATION | PHASE1

45 participants

GPC2 CAR T Cells for Relapsed or Refractory Neuroblastoma and Metastatic Retinoblastoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-05-23
Completion:: 2028-01-30

Conditions

Refractory Neuroblastoma
Relapsed Neuroblastoma
High-risk Neuroblastoma
Retinoblastoma
Metastatic Retinoblastoma

Interventions

BIOLOGICAL

No Results Yet

NCT05630235 | COMPLETED | PHASE1/PHASE2

6 participants

Effects of CBD/CBD-A Oral Extract on Resting-state EEG and Neuropathic Pain Symptoms After SCI

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-06-16
Completion:: 2026-08-13

Conditions

SCI - Spinal Cord Injury
Neuropathic Pain

Interventions

DRUG
OTHER

No Results Yet

NCT05626114 | RECRUITING | PHASE2

60 participants

A Study to Optimize Subretinal Surgical Delivery and to Evaluate Safety and Activity of Opregen in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (GAlette); Adaptive Optics (AO) Retinal Imaging Substudy in Association With Study GR44251

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-03-23
Completion:: 2031-03-01

Conditions

Geographic Atrophy

Interventions

BIOLOGICAL

No Results Yet

NCT05609630 | RECRUITING | PHASE3

90 participants

Study of Oral Upadacitinib and Subcutaneous/Intravenous Tocilizumab to Evaluate Change in Disease Activity, Adverse Events and How Drug Moves Through the Body of Pediatric and Adolescent Participants With Active Systemic Juvenile Idiopathic Arthritis.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-10-02
Completion:: 2029-06-30

Conditions

Juvenile Idiopathic Arthritis

Interventions

DRUG

No Results Yet

NCT05602038 | COMPLETED | NA

100 participants

Comparative Study on the Effect of Quadratus Lumborum Block Versus Intrathecal Morphine on the Incidence of Chronic Pain Post Caesarean Section

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-02-01
Completion:: 2023-12-01

Conditions

Chronic Post Cesarean Pain

Interventions

PROCEDURE
DRUG

No Results Yet

NCT05592366 | RECRUITING | NA

128 participants

Dementia Care Partner Hospital Assessment Tool

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2024-04-02
Completion:: 2027-05-31

Conditions

Alzheimer Disease
Dementia

Interventions

BEHAVIORAL

No Results Yet

NCT05584241 | COMPLETED | NA

102 participants

Behavioral Change Following Alzheimer's Disease (AD) Biomarker Disclosure

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-02-20
Completion:: 2026-05-07

Conditions

Mild Cognitive Impairment
Alzheimer Disease
Amnestic Mild Cognitive Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT05565586 | ACTIVE_NOT_RECRUITING | NA

31 participants

Impact of High Dietary Fiber on Microbiome and Vaccine Responses

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2022-08-23
Completion:: 2029-01-02

Conditions

Influenza

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT05541250 | RECRUITING | PHASE1

30 participants

Safety and Efficacy of Autologous Human Schwann Cell (ahSC) Augmentation in Severe Peripheral Nerve Injury (PNI)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-05-04
Completion:: 2026-09-29

Conditions

Peripheral Nerve Injury

Interventions

BIOLOGICAL

No Results Yet

NCT05510908 | COMPLETED

460 participants

Use of a Screening Tool to Describe HIV-Related Cancer Burden and Patient Characteristics in the AMC

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-07-25
Completion:: 2025-02-28

Conditions

HIV-Associated Malignant Neoplasm
HIV Infections
Cancer
AIDS Related Lymphoma
AIDS-related Kaposi Sarcoma
AIDS-Related Malignancy
Anal Cancer
HPV-Related Malignancy

Interventions

OTHER

Results Available