Patient Derived Vascularized MicroTumor Model of Gastrointestinal Peritoneal Carcinomatosis
NCT05844865 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2025-07-29
Summary
This is a pilot study gathering and using samples and data from patients with gastrointestinal peritoneal carcinomatosis. Participants will be asked for permission to provide blood and ascites/peritoneal wash fluid, tumor samples during their planned surgical procedure.
Conditions
- Peritoneal Carcinomatosis
- Gastrointestinal Peritoneal Carcinomatosis
Interventions
- OTHER
-
Biospecimen Collection (Blood, Ascites/Peritoneal Wash Fluid and/or Tumor Samples)
Subjects with a known diagnosis of GI primary tumor with or without PC, with a planned standard of care surgery.
Sponsors & Collaborators
-
University of California, Irvine
lead OTHER
Principal Investigators
-
Maheswari Senthil, MD FACS · Chao Family Comprehensive Cancer Center
Study Design
- Allocation
- NA
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-05-04
- Primary Completion
- 2026-12-31
- Completion
- 2026-12-31
Countries
- United States
Study Locations
More Related Trials
-
Complete Cytoreduction Followed by IP and Systemic Chemotherapies for Gastric Cancer With Peritoneal Carcinomatosis
NCT04547725 ·Status: RECRUITING ·Phase: NA
-
Effect of Peritoneal Lavage on Surgery-induced Positive Peritoneal Cytology in Gastric Cancer Patients
NCT02287168 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Intra-peritoneal Environmental Changes Following Surgery
NCT02102074 ·Status: UNKNOWN
-
Venous Thromboembolism and Haemostatic Disturbances in Patients With Upper Gastrointestinal Cancer
NCT00660205 ·Status: COMPLETED
-
Plasma 5hmC Signatures as a Marker of Colorectal / Appendiceal Peritoneal Metastasis
NCT04157322 ·Status: ACTIVE_NOT_RECRUITING
-
The Role of Pre-operative and Post-operative Circulating Tumor Cells in Gastric Cancer.
NCT05752357 ·Status: UNKNOWN
-
Development of a Clinical and Biological Database in Peritoneal Carcinosis (BCB CARCINOSE)
NCT04221464 ·Status: RECRUITING ·Phase: NA
-
Elimination of Peritoneal Tumor Cells With Extensive Peritoneal Lavage During Surgery in Patients With Gastric Cancer
NCT01476553 ·Status: TERMINATED ·Phase: NA
-
Evaluation of NETs in Patients With Solid Cancers Associated With a High Risk of Venous Thromboembolic Events
NCT04294589 ·Status: UNKNOWN
-
Role of the Peritoneal Microenvironment in the Pathogenesis and Spread of Colorectal Carcinomatosis
NCT03777943 ·Status: COMPLETED
-
Solid Tumor Cancer Surgery With or Without Intraoperative Imaging: A Registry
NCT02852252 ·Status: COMPLETED
-
Total/Subtotal Colectomy in Ovarian Cancer
NCT02595021 ·Status: UNKNOWN ·Phase: PHASE2
-
Quality of Life and Function of Patients With Pelvic Tumors After Undergoing Hemipelvectomy
NCT05134142 ·Status: RECRUITING
-
Study of Plasma Tumor-promoting Factors and Immune Function After Laparotomy, Cytoreductive Surgery and HIPEC vs. PIPAC in Patients With Peritoneal Metastasis
NCT04122885 ·Status: UNKNOWN
-
Generation of Organoids of Neuroendocrine Neoplasms of the Gastro-Entero-Pancreatic Tract Obtained From Patients Undergoing Surgery
NCT06519500 ·Status: RECRUITING
-
Locally Advanced Rectal Cancer - Exfoliated Peritoneal Tumor Cells
NCT02113384 ·Status: ACTIVE_NOT_RECRUITING
-
Efficacy of HIPEC in Patients With Colorectal Cancer at High Risk of Peritoneal Carcinomatosis
NCT04370925 ·Status: RECRUITING ·Phase: PHASE3
-
Identify the Clinical Significance and Potential Implications of Peritoneal Washing Cytology (PWC) in Patients With Pancreatic Cancer
NCT01127815 ·Status: UNKNOWN
-
The Role of Vascular Reconstruction in the Setting of Pelvic Exenteration
NCT04948879 ·Status: UNKNOWN
-
Portal Vein Thrombosis Associated With Unresectable Pancreatic Cancers : a Prospective Multicentric Cohort Study
NCT04814251 ·Status: UNKNOWN
-
Treatment Outcomes of Retroperitoneal Sarcoma
NCT06612671 ·Status: ACTIVE_NOT_RECRUITING
-
A Pilot Study of Perihepatic Phlebotomy During Hepatic Resections
NCT01749332 ·Status: COMPLETED ·Phase: NA
-
Research of Double-positive Circulating Cells (Tumor Marker / CD45+) in Several Types of Metastatic Cancers
NCT06967961 ·Status: RECRUITING ·Phase: NA
-
Micrometastasis in Gastrointestinal Cancer
NCT01919151 ·Status: UNKNOWN
-
Diagnostic Laparoscopy in the Preoperative Staging of Pancreatobiliary Cancer
NCT02479984 ·Status: UNKNOWN ·Phase: NA