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Prevention of Post-Operative Nausea and Vomiting With Propofol Infusion

NCT05759481 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 68

Last updated 2025-04-02

No results posted yet for this study

Summary

The purpose of this study is to clarify whether or not a low-dose propofol infusion can effectively prevent postoperative nausea and vomiting (PONV) in patients who have a documented history of PONV and/or motion sickness.

Conditions

  • Post-operative Nausea and Vomiting

Interventions

DRUG

Propofol

Propofol is administered starting at surgery induction and ending at skin closure

OTHER

Placebo

Placebo is administered starting at surgery induction and ending at skin closure

Sponsors & Collaborators

  • Milton S. Hershey Medical Center

    lead OTHER

Principal Investigators

  • Sonal Sharma, MD · Assistant Professor, Department of Anesthesiology and Perioperative Medicine

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-02-01
Primary Completion
2025-03-12
Completion
2025-03-12
FDA Drug
Yes

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05759481 on ClinicalTrials.gov