Clinical Trials Updated in 2026

NCT05814627 | COMPLETED | PHASE3

487 participants

Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib Compared to Subcutaneous Adalimumab in Adult Participants With Moderate to Severe Rheumatoid Arthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-06-15
Completion:: 2026-07-15

Conditions

Rheumatoid Arthritis

Interventions

DRUG

No Results Yet

NCT05797610 | ACTIVE_NOT_RECRUITING | PHASE3

459 participants

A Study to Evaluate the Efficacy and Safety of Sefaxersen (RO7434656) in Participants With Primary Immunoglobulin A (IgA) Nephropathy at High Risk of Progression

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-08-08
Completion:: 2026-08-31

Conditions

Primary IgA Nephropathy

Interventions

DRUG

No Results Yet

NCT05793320 | COMPLETED | NA

250 participants

Carpal Tunnel Release With Risk Factors for Amyloidosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-08-03
Completion:: 2025-12-03

Conditions

Amyloidosis

Interventions

PROCEDURE

No Results Yet

NCT05792189 | RECRUITING | NA

100 participants

Distal Femur Fx: ORIF(Open Reduction and Internal Fixation) vs DFR (Distal Femur Replacement Total Knee Arthroplasty)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-04-12
Completion:: 2029-04-01

Conditions

Distal Femur Fracture

Interventions

OTHER

No Results Yet

NCT05776953 | COMPLETED | PHASE4

86 participants

Evaluation of the Effects of Ketorolac Dose on Duration of Analgesia in Emergency Department (ED) Renal Colic Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-12-21
Completion:: 2026-08-12

Conditions

Renal Colic
Flank Pain
Emergencies
Analgesia

Interventions

DRUG

No Results Yet

NCT05763537 | RECRUITING | NA

75 participants

Understanding the Role of Doulas in Supporting People With PMADs

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2024-11-26
Completion:: 2026-12-31

Conditions

Maternal Health
Pregnancy
Delivery, Obstetric
Self Efficacy
Social Support
Mental Health
Substance-Related Disorders
Postpartum Depression
Depression
Mental Health Services

Interventions

BEHAVIORAL

No Results Yet

NCT05759481 | COMPLETED | PHASE2

65 participants

Prevention of Post-Operative Nausea and Vomiting With Propofol Infusion

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2024-02-01
Completion:: 2025-03-12

Conditions

Post-operative Nausea and Vomiting

Interventions

DRUG

Results Available

NCT05758116 | COMPLETED | PHASE2

5 participants

Tislelizumab Consolidation Therapy After Radiotherapy or Sequential Chemoradiation in Locally Advanced NSCLC Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2022-07-07
Completion:: 2026-06-30

Conditions

Non-small Cell Lung Cancer
Consolidation Immunotherapy
Radiotherapy or Sequential Chemoradiation

Interventions

DRUG

No Results Yet

NCT05753176 | COMPLETED | NA

412 participants

Online 1-Day CBT-Based Workshops for Preventing Postpartum Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2022-11-10
Completion:: 2025-12-12

Conditions

Postpartum Depression
Postpartum Anxiety

Interventions

BEHAVIORAL

No Results Yet

NCT05750953 | COMPLETED | NA

204 participants

Nurse-assisted Intervention "eHealth@ Hospital -2-home"

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-05-05
Completion:: 2025-12-15

Conditions

Non Communicable Diseases
Heart Failure
Colon Rectal Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT05748171 | RECRUITING | PHASE2

100 participants

A Study to Learn More About the Study Medicine Called Inotuzumab Ozogamicin (InO) in Children (1 to <18 Years) With First Relapse ALL

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-05-17
Completion:: 2033-05-21

Conditions

ACUTE LYMPHOBLASTIC LEUKEMIA

Interventions

DRUG

No Results Yet

NCT05732870 | RECRUITING

2000 participants

OSTEOMICS: Identifying Regulators of Bone Homeostasis

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-01-12
Completion:: 2027-12-31

Conditions

Osteoporosis
Osteoarthritis
Bone Diseases
Bone Fracture
Bone Marrow Disease

Interventions

PROCEDURE

No Results Yet

NCT05725655 | ACTIVE_NOT_RECRUITING | NA

30 participants

Hot Water Immersion After Myocardial Infarction

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-10-26
Completion:: 2027-07-30

Conditions

Cardiac Disease
Cardiac Rehabilitation

Interventions

OTHER

No Results Yet

NCT05722327 | ACTIVE_NOT_RECRUITING | PHASE1

24 participants

Phase I Trial of Adagrasib (MRTX849) in Combination With Cetuximab and Irinotecan in Patients With Colorectal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-12-06
Completion:: 2027-09-30

Conditions

Colon Cancer
Colorectal Cancer

Interventions

DRUG

No Results Yet

NCT05713279 | TERMINATED | NA

13 participants

Study of Flonoltinib Maleate Tablets in the Treatment of Severe Novel Coronavirus (COVID-19) Infection

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-05-23
Completion:: 2023-12-01

Conditions

COVID-19

Interventions

DRUG

No Results Yet

NCT05705193 | COMPLETED | NA

39 participants

Brain-Training Treatment for Long COVID in Older Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-04-07
Completion:: 2025-12-13

Conditions

Post-Acute COVID-19 Syndrome

Interventions

OTHER

No Results Yet

NCT05685303 | RECRUITING | NA

700 participants

Alleviant ALLAY-HF Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-01-10
Completion:: 2027-12-01

Conditions

Heart Failure

Interventions

DEVICE
OTHER

No Results Yet

NCT05664516 | RECRUITING | PHASE2

60 participants

A Study of the Effects of Oxytocin in Adults With Binge-eating Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-03-07
Completion:: 2026-12-31

Conditions

Binge-eating Disorder

Interventions

DRUG

No Results Yet

NCT05650749 | ENROLLING_BY_INVITATION | PHASE1

45 participants

GPC2 CAR T Cells for Relapsed or Refractory Neuroblastoma and Metastatic Retinoblastoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-05-23
Completion:: 2028-01-30

Conditions

Refractory Neuroblastoma
Relapsed Neuroblastoma
High-risk Neuroblastoma
Retinoblastoma
Metastatic Retinoblastoma

Interventions

BIOLOGICAL

No Results Yet

NCT05630235 | COMPLETED | PHASE1/PHASE2

6 participants

Effects of CBD/CBD-A Oral Extract on Resting-state EEG and Neuropathic Pain Symptoms After SCI

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-06-16
Completion:: 2026-08-13

Conditions

SCI - Spinal Cord Injury
Neuropathic Pain

Interventions

DRUG
OTHER

No Results Yet

NCT05626114 | RECRUITING | PHASE2

60 participants

A Study to Optimize Subretinal Surgical Delivery and to Evaluate Safety and Activity of Opregen in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (GAlette); Adaptive Optics (AO) Retinal Imaging Substudy in Association With Study GR44251

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-03-23
Completion:: 2031-03-01

Conditions

Geographic Atrophy

Interventions

BIOLOGICAL

No Results Yet

NCT05609630 | RECRUITING | PHASE3

90 participants

Study of Oral Upadacitinib and Subcutaneous/Intravenous Tocilizumab to Evaluate Change in Disease Activity, Adverse Events and How Drug Moves Through the Body of Pediatric and Adolescent Participants With Active Systemic Juvenile Idiopathic Arthritis.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-10-02
Completion:: 2029-06-30

Conditions

Juvenile Idiopathic Arthritis

Interventions

DRUG

No Results Yet

NCT05602038 | COMPLETED | NA

100 participants

Comparative Study on the Effect of Quadratus Lumborum Block Versus Intrathecal Morphine on the Incidence of Chronic Pain Post Caesarean Section

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-02-01
Completion:: 2023-12-01

Conditions

Chronic Post Cesarean Pain

Interventions

PROCEDURE
DRUG

No Results Yet

NCT05592366 | RECRUITING | NA

128 participants

Dementia Care Partner Hospital Assessment Tool

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2024-04-02
Completion:: 2027-05-31

Conditions

Alzheimer Disease
Dementia

Interventions

BEHAVIORAL

No Results Yet

NCT05584241 | COMPLETED | NA

102 participants

Behavioral Change Following Alzheimer's Disease (AD) Biomarker Disclosure

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-02-20
Completion:: 2026-05-07

Conditions

Mild Cognitive Impairment
Alzheimer Disease
Amnestic Mild Cognitive Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT05565586 | ACTIVE_NOT_RECRUITING | NA

31 participants

Impact of High Dietary Fiber on Microbiome and Vaccine Responses

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2022-08-23
Completion:: 2029-01-02

Conditions

Influenza

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT05541250 | RECRUITING | PHASE1

30 participants

Safety and Efficacy of Autologous Human Schwann Cell (ahSC) Augmentation in Severe Peripheral Nerve Injury (PNI)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-05-04
Completion:: 2026-09-29

Conditions

Peripheral Nerve Injury

Interventions

BIOLOGICAL

No Results Yet

NCT05510908 | COMPLETED

460 participants

Use of a Screening Tool to Describe HIV-Related Cancer Burden and Patient Characteristics in the AMC

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-07-25
Completion:: 2025-02-28

Conditions

HIV-Associated Malignant Neoplasm
HIV Infections
Cancer
AIDS Related Lymphoma
AIDS-related Kaposi Sarcoma
AIDS-Related Malignancy
Anal Cancer
HPV-Related Malignancy

Interventions

OTHER

Results Available

NCT05506085 | RECRUITING

12 participants

Deep Brain Stimulation for Laryngeal Dystonia: From Mechanism to Optimal Application

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2022-10-01
Completion:: 2030-08-01

Conditions

Laryngeal Dystonia
Adductor Spastic Dysphonia of Dystonia

Interventions

DEVICE

No Results Yet

NCT05472987 | RECRUITING | NA

200 participants

Robotic Versus Open Ventral Hernia Repair

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2022-07-25
Completion:: 2027-08-01

Conditions

Ventral Hernia

Interventions

PROCEDURE

No Results Yet

NCT05466149 | ACTIVE_NOT_RECRUITING | PHASE2

100 participants

Efficacy and Safety of Furmonertinib in Patients With Locally Advanced or Metastatic NSCLC With EGFR Exon 20 Insertion

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2022-09-27
Completion:: 2025-06-27

Conditions

NSCLC

Interventions

DRUG

No Results Yet

NCT05464823 | ACTIVE_NOT_RECRUITING | NA

111 participants

Feasibility of Combined Genomics/Transcriptomics for Patients With Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2022-07-07
Completion:: 2027-05-12

Conditions

Lymphoma

Interventions

OTHER

No Results Yet

NCT05453799 | SUSPENDED | PHASE2

54 participants

Vudalimab for the Treatment of Locally Advanced or Metastatic Anaplastic Thyroid Cancer or Hurthle Cell Thyroid Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2022-07-21
Completion:: 2023-10-31

Conditions

Locally Advanced Thyroid Gland Anaplastic Carcinoma
Metastatic Thyroid Gland Anaplastic Carcinoma
Metastatic Thyroid Gland Oncocytic Carcinoma

Interventions

DRUG

No Results Yet

NCT05429411 | COMPLETED | NA

49 participants

Nonsilicone Gel Sheet for Burn Hypertrophic Scars

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2016-04-22
Completion:: 2025-06-20

Conditions

Burn Scar

Interventions

OTHER

No Results Yet

NCT05428176 | ACTIVE_NOT_RECRUITING | NA

332 participants

A High Intensity Electronic Health Intervention for the Reduction of Learning Disparities in Childhood Cancer Survivors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2022-09-10
Completion:: 2027-06-30

Conditions

Acute Leukemia
Acute Lymphoblastic Leukemia
Acute Myeloid Leukemia
Lymphoblastic Lymphoma

Interventions

OTHER

No Results Yet

NCT05412394 | RECRUITING | PHASE4

26 participants

Once Weekly Infant Corticosteroid Trial for DMD

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-04-30
Completion:: 2028-08-31

Conditions

Duchenne Muscular Dystrophy

Interventions

DRUG

No Results Yet

NCT05408143 | COMPLETED | NA

254 participants

An Enhanced Home-Based Telemedicine Program Using Remote Examination Devices for Children With Medical Complexity

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2022-07-12
Completion:: 2024-08-26

Conditions

Chronic Diseases in Children

Interventions

OTHER
DEVICE

Results Available

NCT05379530 | NOT_YET_RECRUITING | NA

60 participants

TEG Use in Children Undergoing Procedures With High Anticipated Blood Loss

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2027-01-01
Completion:: 2028-12-01

Conditions

Surgical Blood Loss
Surgical Hemorrhage
Post Operative Hemorrhage

Interventions

DIAGNOSTIC_TEST
OTHER

No Results Yet

NCT05373095 | COMPLETED | NA

692 participants

Rudi Kundini, Pamoja Kundini

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-10-23
Completion:: 2026-04-10

Conditions

HIV (Human Immunodeficiency Virus)

Interventions

BEHAVIORAL

No Results Yet

NCT05372159 | ACTIVE_NOT_RECRUITING

1000 participants

Vanderbilt Memory and Aging Project

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2012-09-17
Completion:: 2027-12-31

Conditions

Alzheimer Disease
Aging
Aged, 80 and Over
Biomarkers
Brain
Case-Control Studies
Cognitive Dysfunction
Neuropsychological Tests

Interventions

OTHER

No Results Yet