Clinical Trials

NCT05354778 | COMPLETED | NA

180 participants

HYDROcortisone Versus Placebo for Severe HospItal-acquired Pneumonia in Intensive Care Patients: the HYDRO-SHIP Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2022-10-16

Completion:

2026-07-31

Conditions

• Healthcare-Associated Pneumonia
• Ventilator Associated Pneumonia

Interventions

• DRUG

No Results Yet

NCT05350475 | ACTIVE_NOT_RECRUITING | NA

102 participants

Protons vs. Photons for High-risk Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2022-03-01

Completion:

2028-12-01

Conditions

• Prostate Cancer
• Radiotherapy Side Effect

Interventions

• RADIATION

No Results Yet

NCT05309668 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

36 participants

Pharmacokinetics, Safety and Efficacy of the Selumetinib Granule Formulation in Children Aged ≥1 to <7 Years With NF1-related Symptomatic, Inoperable PN

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2022-01-21

Completion:

2027-11-30

Conditions

• Neurofibromatosis Type 1

Interventions

• DRUG

Results Available

NCT05288205 | RECRUITING | PHASE1/PHASE2

240 participants

Phase 1/2a Study of JAB-21822 Plus JAB-3312 in Patients With Advanced Solid Tumors Harboring KRAS p.G12C Mutation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2022-04-14

Completion:

2027-03-31

Conditions

• KRAS P.G12C
• Non-small Cell Lung Cancer
• Colorectal Cancer
• Pancreatic Ductal Carcinoma

Interventions

• DRUG

No Results Yet

NCT05276726 | RECRUITING | PHASE1/PHASE2

104 participants

A Study of JAB-21822 in Advanced or Metastatic NSCLC With KRAS p.G12C and STK11 Co-mutation and Wild-type KEAP1

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2022-08-17

Completion:

2027-08-31

Conditions

• Non-small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT05259501 | COMPLETED | NA

15 participants

Remote Methadone Ingestion Surveillance Trial (RMIST)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2025-01-15

Completion:

2025-03-13

Conditions

• Opioid Use Disorder

Interventions

• OTHER

Results Available

NCT05223998 | ENROLLING_BY_INVITATION | NA

10 participants

Manual Implantation of Full-Thickness Skin Microcolumns

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2024-10-28

Completion:

2026-12-31

Conditions

• Wound of Skin
• Burns

Interventions

• PROCEDURE

No Results Yet

NCT05223192 | RECRUITING | NA

120 participants

The Effects of Entrainment on Respiratory Stability and Cerebral Oxygenation in Preterm Infants

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2022-04-01

Completion:

2026-12-31

Conditions

• Prematurity

Interventions

• BEHAVIORAL

No Results Yet

NCT05220917 | ACTIVE_NOT_RECRUITING

781430 participants

Comparative Effectiveness and Safety of Four Second Line Pharmacological Strategies in Type 2 Diabetes Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2021-08-01

Completion:

2026-05-31

Conditions

• Cardiovascular Events
• Type2 Diabetes
• Renal Disease

Interventions

• DRUG

No Results Yet

NCT05219695 | RECRUITING | PHASE1

82 participants

Medical Imaging and Focused Ultrasound Treatment for Breast Tumors Using Harmonic Motion Imaging (HMI)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2022-01-19

Completion:

2031-05-31

Conditions

• Fibroadenoma
• Breast Cancer Stage I

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT05211323 | ACTIVE_NOT_RECRUITING | PHASE2

4 participants

A Study to Determine Whether Chemotherapy and Atezolizumab is Better Than Chemotherapy, Bevacizumab and Atezolizumab in Patients With Advanced Liver Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2022-12-07

Completion:

2026-01-20

Conditions

• Combined Hepatocellular Carcinoma and Cholangiocarcinoma
• Stage III Liver Cancer
• Stage IV Liver Cancer

Interventions

• BIOLOGICAL
• PROCEDURE
• DRUG

No Results Yet

NCT05206955 | RECRUITING | PHASE3

42 participants

Study of Tadalafil vs. Placebo for Improving Hemodynamics and End-Organ Dysfunction in Fontan Physiology

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2022-09-16

Completion:

2026-11-30

Conditions

• Fontan Palliation

Interventions

• DRUG

No Results Yet

NCT05206422 | COMPLETED | NA

21 participants

DORAYA-HF Early Feasibility Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2022-10-05

Completion:

2026-01-31

Conditions

• Acute Decompensated Heart Failure

Interventions

• DEVICE

No Results Yet

NCT05205382 | COMPLETED | NA

116 participants

Assessing the Effect of Nicotine Reduction on ENDS User's Addiction and Exposures

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2022-04-01

Completion:

2025-04-15

Conditions

• Electronic Cigarette Use

Interventions

• OTHER

Results Available

NCT05203614 | COMPLETED | NA

60 participants

Positive Activities for Asian American Cancer Patients and Caregivers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2021-11-30

Completion:

2024-11-19

Conditions

• Cancer

Interventions

• BEHAVIORAL

Results Available

NCT05198284 | ACTIVE_NOT_RECRUITING

2000 participants

Prospective Decision Impact Clinical Utility Trial of KidneyIntelX

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2021-11-01

Completion:

2023-12-01

Conditions

• Diabetic Kidney Disease
• Chronic Kidney Diseases
• Chronic Kidney Disease Stage 1
• Chronic Kidney Disease Stage 2
• Chronic Kidney Disease Stage 3

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05178420 | COMPLETED | NA

1880 participants

STREAM Trial - Statins in Multimorbid Older Adults Without Cardiovascular Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2021-11-16

Completion:

2026-04-30

Conditions

• Statin Treatment for Primary Prevention

Interventions

• OTHER

No Results Yet

NCT05176639 | COMPLETED | PHASE3

113 participants

A Safety, Tolerability, and Efficacy Study of Veligrotug (VRDN 001) in Participants With Thyroid Eye Disease (TED)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2022-11-16

Completion:

2024-07-15

Conditions

• Thyroid Eye Disease

Interventions

• DRUG

Results Available

NCT05135559 | ACTIVE_NOT_RECRUITING | PHASE3

153 participants

A Research Study on How Well Concizumab Works for You if You Have Haemophilia A or B With or Without Inhibitors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2022-03-24

Completion:

2026-04-21

Conditions

• Haemophilia A and B With and Without Inhibitors

Interventions

• DRUG

No Results Yet

NCT05135533 | COMPLETED | NA

53 participants

Neuromodulation and Dynamic Balance in Stroke

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2023-08-28

Completion:

2025-07-24

Conditions

• Stroke

Interventions

• DEVICE
• OTHER

Results Available

NCT05124392 | RECRUITING

150 participants

OBSERVE: Biomarkers in Individuals at Risk for Prion Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2017-12-01

Completion:

2027-06-01

Conditions

• CJD (Creutzfeldt Jakob Disease)
• Prion Diseases
• GSS
• FFI
• Familial Fatal Insomnia

No Results Yet

NCT05115344 | WITHDRAWN | PHASE1

0 participants

Study of Flonoltinib Maleate Tablets in the Treatment of Proliferative Bone Marrow Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2021-11-12

Completion:

2022-12-29

Conditions

• Myeloproliferative Neoplasm (MPN)
• Myelofibrosis，MF

Interventions

• DRUG

No Results Yet

NCT05086250 | COMPLETED | EARLY_PHASE1

12 participants

Feasibility Study of Oral Ketamine Versus Placebo for the Treatment of Anxiety in Patients With Pancreatic Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2022-10-20

Completion:

2026-03-06

Conditions

• Anxiety
• Pancreatic Cancer

Interventions

• DRUG

No Results Yet

NCT05052216 | RECRUITING

120 participants

Development of a Wearable Point of Care Monitoring Device for Pediatric Obstructive Sleep Apnea

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2022-08-25

Completion:

2028-01-31

Conditions

• Pediatric Obstructive Sleep Apnea

No Results Yet

NCT05009329 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

315 participants

A Study of JAB-21822 in Adult Patients With Advanced Solid Tumors Harboring KRAS p.G12C Mutation in China

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2021-07-26

Completion:

2026-08-31

Conditions

• NSCLC
• Solid Tumor

Interventions

• DRUG

No Results Yet

NCT05001880 | RECRUITING | PHASE2

66 participants

Chemotherapy With or Without Immunotherapy for Peritoneal Mesothelioma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2022-03-22

Completion:

2027-08-01

Conditions

• Peritoneal Malignant Mesothelioma

Interventions

• BIOLOGICAL
• PROCEDURE
• DRUG

No Results Yet

NCT04960514 | ACTIVE_NOT_RECRUITING

2000 participants

Prospective Decision Impact Trial of KidneyIntelX

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2021-11-22

Completion:

2023-12-01

Conditions

• Diabetic Kidney Disease
• Chronic Kidney Disease Stage 1
• Chronic Kidney Disease Stage 2
• Chronic Kidney Disease, Stage 3 (Moderate)

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04944940 | RECRUITING

70 participants

Clinical, Molecular and Imaging Biomarkers in Spinal and Bulbar Muscular Atrophy (SBMA)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2021-10-25

Completion:

2026-12-30

Conditions

• Spinal and Bulbar Muscular Atrophy
• Kennedys Disease
• Motor Neuron Disease

No Results Yet

NCT04940507 | ACTIVE_NOT_RECRUITING | NA

50 participants

BRAINFUL (BRAIN Tumor Focused Ultrasound-enabled Liquid Biopsy) Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2021-06-10

Completion:

2026-12-31

Conditions

• Brain Neoplasms
• Liquid Biopsy

Interventions

• PROCEDURE

No Results Yet

NCT04924101 | COMPLETED | PHASE2

122 participants

Efficacy and Safety of Pembrolizumab Plus Investigational Agents in Combination With Chemotherapy as First-Line Treatment in Extensive-Stage Small Cell Lung Cancer (ES-SCLC) (MK-3475-B99/ KEYNOTE-B99)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2021-07-15

Completion:

2025-06-23

Conditions

• Small Cell Lung Cancer

Interventions

• BIOLOGICAL
• DRUG

Results Available

NCT04912739 | RECRUITING

18000 participants

Targeted Health Dialogues in Primary Care

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2020-10-01

Completion:

2030-12-31

Conditions

• Health Behaviors
• Risk Factors
• Cardiovascular Diseases
• Cancer
• Serious Diseases

Interventions

• BEHAVIORAL

No Results Yet

NCT04910269 | TERMINATED | PHASE3

741 participants

Outpatient Treatment With Anti-Coronavirus Immunoglobulin

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2021-08-06

Completion:

2026-05-24

Conditions

• COVID
• SARS-CoV2 Infection
• Covid19

Interventions

• BIOLOGICAL
• OTHER

No Results Yet

NCT04853342 | RECRUITING | PHASE3

318 participants

To Assess the Efficacy and Safety of Furmonertinib Versus Placebo, in Patients With Epidermal Growth Factor Receptor Mutation Positive Stage II-IIIA Non-small Cell Lung Carcinoma, Following Complete Tumour Resection With or Without Adjuvant Chemotherapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2021-06-07

Completion:

2026-12-31

Conditions

• Non-small Cell Lung Carcinoma

Interventions

• DRUG

No Results Yet

NCT04828096 | ACTIVE_NOT_RECRUITING | NA

324 participants

Retention With Three Different Bonded Retainers a Multicenter, Randomized Controlled Trial With 5-year Follow-up

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2021-03-25

Completion:

2030-09-30

Conditions

• Dental Malocclusion
• Stability

Interventions

• OTHER

No Results Yet

NCT04820400 | COMPLETED | NA

82 participants

Reducing Pain and Anxiety During Dressing Changes After Burn Surgery Using Virtual Reality

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2021-03-24

Completion:

2025-02-12

Conditions

• Pain, Postoperative
• Trauma
• Burns

Interventions

• OTHER

No Results Yet

NCT04802395 | RECRUITING

10000 participants

Real World Evidence Clinical Utility Study of KidneyIntelX

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2021-03-02

Completion:

2026-12-01

Conditions

• Chronic Kidney Diseases
• Diabetic Kidney Disease

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04796493 | ACTIVE_NOT_RECRUITING

98 participants

Objective Grading of MTS With LSCI and Thermography

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2021-03-16

Completion:

2023-06-30

Conditions

• Mesenteric Traction Syndrome

No Results Yet

NCT04791358 | ACTIVE_NOT_RECRUITING

1500 participants

Decision Impact Trial of KidneyIntelX

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2021-11-01

Completion:

2026-11-01

Conditions

• Diabetic Kidney Disease

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04780568 | ACTIVE_NOT_RECRUITING | PHASE1

24 participants

Osimertinib and Tegavivint as First-Line Therapy for the Treatment of Metastatic EGFR-Mutant Non-small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2022-01-18

Completion:

2026-12-31

Conditions

• Metastatic Lung Non-Small Cell Carcinoma
• Stage IV Lung Cancer AJCC v8
• Stage IVA Lung Cancer AJCC v8
• Stage IVB Lung Cancer AJCC v8

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT04772131 | ACTIVE_NOT_RECRUITING | NA

300 participants

Desara ® One Single Incision Sling 522 Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2021-11-01

Completion:

2026-08-07

Conditions

• Stress Urinary Incontinence

Interventions

• DEVICE

No Results Yet