Clinical Trials Updated in 2026

NCT05562518 | COMPLETED | PHASE4

31 participants

GRACE-trial: a Randomized Active-controlled Trial for vulvovaGinal atRophy in breAst Cancer Patients on Endocrine Therapy.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2022-03-21
Completion:: 2026-03-02

Conditions

Vulvovaginal Atrophy
Breast Cancer

Interventions

DRUG

No Results Yet

NCT05557409 | COMPLETED | PHASE3

408 participants

A Study to Assess the Efficacy and Safety of AXS-05 in Subjects With Alzheimer's Disease Agitation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2022-09-06
Completion:: 2024-11-21

Conditions

Agitation in Patients With Dementia of the Alzheimer's Type
Alzheimer Disease
Agitation

Interventions

DRUG

Results Available

NCT05543200 | RECRUITING

7500 participants

BPH Global Registry

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-13
Start Date:: 2023-03-13
Completion:: 2027-12-31

Conditions

Benign Prostatic Hyperplasia
Lower Urinary Tract Symptoms

No Results Yet

NCT05534386 | RECRUITING | NA

486 participants

A Self-management Based Survivorship Intervention for Chinese Cancer Survivors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2023-04-12
Completion:: 2026-12-31

Conditions

Physical Symptom Distress
Weight Management
Neoplasms

Interventions

BEHAVIORAL

No Results Yet

NCT05530317 | TERMINATED | NA

13 participants

CArdiac REhabilitation for Building Exertional heArt Rate for Chronotropic Incompetence in Long COVID-19

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2022-12-21
Completion:: 2026-07-31

Conditions

Long COVID
COVID-19

Interventions

BEHAVIORAL

No Results Yet

NCT05528380 | COMPLETED | NA

16 participants

Development of a Lifestyle Physical Activity Intervention to Reduce Risk for Perinatal Cannabis Use

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2022-01-30
Completion:: 2024-05-15

Conditions

Pregnancy
Cannabis

Interventions

BEHAVIORAL

Results Available

NCT05519449 | RECRUITING | PHASE1

272 participants

Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2022-09-15
Completion:: 2027-07-31

Conditions

Prostate Cancer
Metastatic Castration-resistant Prostate Cancer
Castration Resistant Prostatic Cancer

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT05489211 | RECRUITING | PHASE2

454 participants

Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2022-09-06
Completion:: 2027-10-01

Conditions

Endometrial Cancer
Gastric Cancer
Metastatic Castration-resistant Prostate Cancer
Ovarian Cancer
Colorectal Cancer
Urothelial Cancer
Biliary Tract Cancer

Interventions

DRUG

No Results Yet

NCT05486234 | RECRUITING | NA

52 participants

CARS: Cannabis and Alcohol Reduction Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2023-01-25
Completion:: 2026-09-30

Conditions

Cannabis Use
Alcohol Use, Unspecified
Substance Use
Substance Use Disorders

Interventions

BEHAVIORAL

No Results Yet

NCT05477927 | RECRUITING | PHASE1

40 participants

Dual-targeting VEGFR1 and PD-L1 CAR-T for Pleural, Peritoneal, or Leptomeningeal Metastases

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2023-02-15
Completion:: 2027-06-30

Conditions

Malignant Peritoneal Effusion
Malignant Ascites
Serous Cavity Metastatises
Leptomeningeal Metastases

Interventions

BIOLOGICAL

No Results Yet

NCT05477134 | COMPLETED | NA

30 participants

Arginine Metabolism in Youth With Type 2 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2023-02-06
Completion:: 2026-06-18

Conditions

Type 2 Diabetes

Interventions

OTHER

No Results Yet

NCT05476939 | RECRUITING | PHASE3

433 participants

Biological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) Eradication 2.0

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2022-09-29
Completion:: 2028-09-30

Conditions

Diffuse Intrinsic Pontine Glioma
Diffuse Midline Glioma, H3 K27M-Mutant
Diffuse Midline Glioma, H3K27-altered

Interventions

DRUG
RADIATION

No Results Yet

NCT05466955 | ACTIVE_NOT_RECRUITING | NA

158 participants

Slashing Two-wheeled Accidents by Leveraging Eyecare

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2024-09-22
Completion:: 2026-10-31

Conditions

Myopia

Interventions

DEVICE

No Results Yet

NCT05462860 | ACTIVE_NOT_RECRUITING | NA

21 participants

Suprathel® Use During Prolonged Field Care to Promote Healing and Reduce the Need for Grafting of Burn Wounds

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2024-09-18
Completion:: 2026-12-09

Conditions

Wound of Skin
Burns

Interventions

OTHER

No Results Yet

NCT05452356 | RECRUITING

2000 participants

Testing VIRTUES Patient Care Sets in Cardiac Patients (VIRTUES Cardiac Care)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-13
Start Date:: 2024-04-18
Completion:: 2027-09-30

Conditions

Heart Diseases
Arrhythmias, Cardiac
Atrial Fibrillation
Cardiovascular Diseases
Pathologic Processes

No Results Yet

NCT05452330 | COMPLETED | NA

30 participants

The Effect of Two Different Massages on Migraine

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2022-07-18
Completion:: 2022-12-09

Conditions

Headache, Migraine
Manuel Therapy

Interventions

OTHER

No Results Yet

NCT05450744 | ACTIVE_NOT_RECRUITING | PHASE1

12 participants

131I-TLX-101 for Treatment of Newly Diagnosed Glioblastoma (IPAX-2)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2023-04-01
Completion:: 2027-06-30

Conditions

Neoplastic Disease
Glioblastoma
Glioblastoma Multiforme

Interventions

DRUG

No Results Yet

NCT05442190 | COMPLETED | PHASE2

15 participants

Topical SGX302 for Mild-to-Moderate Psoriasis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2022-12-14
Completion:: 2025-10-22

Conditions

Psoriasis
Plaque Psoriasis
Psoriasis Vulgaris

Interventions

DRUG

No Results Yet

NCT05438095 | ACTIVE_NOT_RECRUITING

150 participants

Medication Adherence in Patients With Sarcoidosis

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-13
Start Date:: 2022-05-11
Completion:: 2027-12-01

Conditions

Medication Adherence
Sarcoidosis

No Results Yet

NCT05435157 | COMPLETED

592 participants

Residual Gastric Volume Measured by Ultrasound in Diabetic Surgical Population Versus Non-diabetic Surgical Population.

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-13
Start Date:: 2022-03-09
Completion:: 2024-12-31

Conditions

Diabetes Mellitus

Results Available

NCT05407675 | COMPLETED | PHASE1/PHASE2

68 participants

A Study to Evaluate the Safety and Tolerability of BMS-986408 Alone and in Combination With Nivolumab or Nivolumab and Ipilimumab in Participants With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2022-08-02
Completion:: 2024-08-22

Conditions

Advanced Solid Tumors

Interventions

DRUG
BIOLOGICAL

Results Available

NCT05357833 | COMPLETED | EARLY_PHASE1

11 participants

Novel Imaging Markers in SPMS

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2022-06-01
Completion:: 2023-09-01

Conditions

Secondary Progressive Multiple Sclerosis
Multiple Sclerosis, Secondary Progressive
Multiple Sclerosis

Interventions

DRUG
DIAGNOSTIC_TEST

No Results Yet

NCT05354778 | COMPLETED | NA

180 participants

HYDROcortisone Versus Placebo for Severe HospItal-acquired Pneumonia in Intensive Care Patients: the HYDRO-SHIP Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2022-10-16
Completion:: 2026-07-31

Conditions

Healthcare-Associated Pneumonia
Ventilator Associated Pneumonia

Interventions

DRUG

No Results Yet

NCT05350475 | ACTIVE_NOT_RECRUITING | NA

102 participants

Protons vs. Photons for High-risk Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2022-03-01
Completion:: 2028-12-01

Conditions

Prostate Cancer
Radiotherapy Side Effect

Interventions

RADIATION

No Results Yet

NCT05309668 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

36 participants

Pharmacokinetics, Safety and Efficacy of the Selumetinib Granule Formulation in Children Aged ≥1 to <7 Years With NF1-related Symptomatic, Inoperable PN

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2022-01-21
Completion:: 2027-11-30

Conditions

Neurofibromatosis Type 1

Interventions

DRUG

Results Available

NCT05288205 | RECRUITING | PHASE1/PHASE2

240 participants

Phase 1/2a Study of JAB-21822 Plus JAB-3312 in Patients With Advanced Solid Tumors Harboring KRAS p.G12C Mutation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2022-04-14
Completion:: 2027-03-31

Conditions

KRAS P.G12C
Non-small Cell Lung Cancer
Colorectal Cancer
Pancreatic Ductal Carcinoma

Interventions

DRUG

No Results Yet

NCT05276726 | RECRUITING | PHASE1/PHASE2

104 participants

A Study of JAB-21822 in Advanced or Metastatic NSCLC With KRAS p.G12C and STK11 Co-mutation and Wild-type KEAP1

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2022-08-17
Completion:: 2027-08-31

Conditions

Non-small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT05259501 | COMPLETED | NA

15 participants

Remote Methadone Ingestion Surveillance Trial (RMIST)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2025-01-15
Completion:: 2025-03-13

Conditions

Opioid Use Disorder

Interventions

OTHER

Results Available

NCT05223998 | ENROLLING_BY_INVITATION | NA

10 participants

Manual Implantation of Full-Thickness Skin Microcolumns

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2024-10-28
Completion:: 2026-12-31

Conditions

Wound of Skin
Burns

Interventions

PROCEDURE

No Results Yet

NCT05223192 | RECRUITING | NA

120 participants

The Effects of Entrainment on Respiratory Stability and Cerebral Oxygenation in Preterm Infants

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2022-04-01
Completion:: 2026-12-31

Conditions

Prematurity

Interventions

BEHAVIORAL

No Results Yet

NCT05220917 | ACTIVE_NOT_RECRUITING

781430 participants

Comparative Effectiveness and Safety of Four Second Line Pharmacological Strategies in Type 2 Diabetes Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-13
Start Date:: 2021-08-01
Completion:: 2026-05-31

Conditions

Cardiovascular Events
Type2 Diabetes
Renal Disease

Interventions

DRUG

No Results Yet

NCT05219695 | RECRUITING | PHASE1

82 participants

Medical Imaging and Focused Ultrasound Treatment for Breast Tumors Using Harmonic Motion Imaging (HMI)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2022-01-19
Completion:: 2031-05-31

Conditions

Fibroadenoma
Breast Cancer Stage I

Interventions

PROCEDURE
DRUG

No Results Yet

NCT05211323 | ACTIVE_NOT_RECRUITING | PHASE2

4 participants

A Study to Determine Whether Chemotherapy and Atezolizumab is Better Than Chemotherapy, Bevacizumab and Atezolizumab in Patients With Advanced Liver Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2022-12-07
Completion:: 2026-01-20

Conditions

Combined Hepatocellular Carcinoma and Cholangiocarcinoma
Stage III Liver Cancer
Stage IV Liver Cancer

Interventions

BIOLOGICAL
PROCEDURE
DRUG

No Results Yet

NCT05206955 | RECRUITING | PHASE3

42 participants

Study of Tadalafil vs. Placebo for Improving Hemodynamics and End-Organ Dysfunction in Fontan Physiology

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2022-09-16
Completion:: 2026-11-30

Conditions

Fontan Palliation

Interventions

DRUG

No Results Yet

NCT05206422 | COMPLETED | NA

21 participants

DORAYA-HF Early Feasibility Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2022-10-05
Completion:: 2026-01-31

Conditions

Acute Decompensated Heart Failure

Interventions

DEVICE

No Results Yet

NCT05205382 | COMPLETED | NA

116 participants

Assessing the Effect of Nicotine Reduction on ENDS User's Addiction and Exposures

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2022-04-01
Completion:: 2025-04-15

Conditions

Electronic Cigarette Use

Interventions

OTHER

Results Available

NCT05203614 | COMPLETED | NA

60 participants

Positive Activities for Asian American Cancer Patients and Caregivers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2021-11-30
Completion:: 2024-11-19

Conditions

Cancer

Interventions

BEHAVIORAL

Results Available

NCT05198284 | ACTIVE_NOT_RECRUITING

2000 participants

Prospective Decision Impact Clinical Utility Trial of KidneyIntelX

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-13
Start Date:: 2021-11-01
Completion:: 2023-12-01

Conditions

Diabetic Kidney Disease
Chronic Kidney Diseases
Chronic Kidney Disease Stage 1
Chronic Kidney Disease Stage 2
Chronic Kidney Disease Stage 3

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05178420 | COMPLETED | NA

1880 participants

STREAM Trial - Statins in Multimorbid Older Adults Without Cardiovascular Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2021-11-16
Completion:: 2026-04-30

Conditions

Statin Treatment for Primary Prevention

Interventions

OTHER

No Results Yet

NCT05176639 | COMPLETED | PHASE3

113 participants

A Safety, Tolerability, and Efficacy Study of Veligrotug (VRDN 001) in Participants With Thyroid Eye Disease (TED)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2022-11-16
Completion:: 2024-07-15

Conditions

Thyroid Eye Disease

Interventions

DRUG

Results Available